{"id":766682,"date":"2023-06-28T09:05:32","date_gmt":"2023-06-28T13:05:32","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/geovax-announces-gedeptin-presentation-at-the-aacr-ahns-head-and-neck-cancer-conference\/"},"modified":"2023-06-28T09:05:32","modified_gmt":"2023-06-28T13:05:32","slug":"geovax-announces-gedeptin-presentation-at-the-aacr-ahns-head-and-neck-cancer-conference","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/geovax-announces-gedeptin-presentation-at-the-aacr-ahns-head-and-neck-cancer-conference\/","title":{"rendered":"GeoVax Announces Gedeptin\u00ae Presentation at the AACR-AHNS Head and Neck Cancer Conference"},"content":{"rendered":"
\n

ATLANTA, GA, June 28, 2023 (GLOBE NEWSWIRE) — via NewMediaWire<\/a> \u2013 GeoVax Labs, Inc. (Nasdaq: GOVX), a biotechnology company developing immunotherapies and vaccines against cancers and infectious diseases, today announced that an abstract regarding GeoVax\u2019s gene therapy candidate, Gedeptin\u00ae<\/sup>, has been selected for poster presentation at the American Association for Cancer Research (AACR) and the American Head and Neck Society (AHNS) joint Head and Neck Cancer Conference, being held from July 7-8, 2023 at the Palais des congr\u00e8s de Montr\u00e9al in Montr\u00e9al, QC, Canada.<\/p>\n

Presentation Details:<\/p>\n\n\n\n\n\n\n
Abstract Title:<\/td>\nPhase 1\/ 2 study of Ad\/PNP with fludarabine for the treatment of head neck
squamous cell carcinoma (HNSCC)<\/p>\n

\u00a0<\/td>\n<\/tr>\n

Abstract Authors:<\/td>\nA. Dimitrios Colevas1<\/sup>, Eric J. Sorscher2<\/sup>, William Parker3<\/sup>, Roan Courtney Raymundo1<\/sup>, Jeong S. Hong2<\/sup>, Regina Rab2<\/sup>, Camilo Henao4<\/sup>, Nikki Schmitt2<\/sup>, Madison Stallings2<\/sup>, Kelly T. McKee, Jr.5<\/sup>, Eben Rosenthal6<\/sup>, Joseph Curry4 <\/sup><\/td>\n<\/tr>\n
\u00a0<\/td>\n\n
\n 1<\/sup>
\n <\/em>
\n Stanford Cancer Institute, Stanford University<\/em>
\n
\n
\n 2<\/sup>
\n <\/em>
\n Emory University School of Medicine<\/em>
\n
\n
\n 3<\/sup>
\n <\/em>
\n PNP Therapeutics, Inc.<\/em>
\n
\n
\n 4<\/sup>
\n <\/em>
\n Thomas Jefferson University<\/em>
\n
\n
\n 5<\/sup>
\n <\/em>
\n GeoVax Labs, Inc.<\/em>
\n
\n
\n 6<\/sup>
\n <\/em>
\n Vanderbilt University<\/em>\n <\/td>\n<\/tr>\n
Date and Time:<\/td>\nFriday, July 7, 4:30 p.m.-6:00 p.m. ET<\/td>\n<\/tr>\n
Presenting Author:<\/td>\nKelly T. McKee, Jr., M.D., MPH, Chief Medical Officer, GeoVax<\/td>\n<\/tr>\n<\/table>\n

\n About Gedeptin<\/strong>
\n
\n \u00ae<\/strong>
\n <\/sup>\n <\/p>\n

Gedeptin is a novel patented product\/technology for the treatment of solid tumors through a gene therapy strategy known as Gene-Directed Enzyme Prodrug Therapy (GDEPT). In GDEPT, a vector is used to selectively transduce tumor cells with a nonhuman gene, which expresses an enzyme that can convert a nontoxic prodrug into a very toxic antitumor compound in situ<\/em>.<\/p>\n

The ongoing Phase 1\/2 trial (ClinicalTrials.gov Identifier: NCT03754933<\/a>) is evaluating the safety and efficacy of repeat cycles of Gedeptin therapy in patients with recurrent head and neck squamous cell carcinoma (HNSCC), with tumor(s) accessible for injection and no curable treatment options. The protocol entails up to five treatment cycles, each consisting of three intra-tumoral injections of Gedeptin over two days followed by infusion of a prodrug, fludarabine phosphate, once a day for three days. A completed Phase 1 dose-ranging study demonstrated that treating a tumor with a single cycle of Gedeptin, followed by fludarabine infusions, was well tolerated, with evidence of a reduction in tumor size in patients with solid tumors.<\/p>\n

The current study is being funded in part by the FDA pursuant to its Orphan Products Clinical Trials Grants Program. The FDA has also granted Gedeptin orphan drug status for the intra-tumoral treatment of anatomically accessible oral and pharyngeal cancers, including cancers of the lip, tongue, gum, floor of mouth, salivary gland, and other oral cavities. GeoVax anticipates completion of the current trial by year-end 2023, after which expanded development of Gedeptin is anticipated, both as mono-therapy and as potential combination therapy in conjunction with Immune Checkpoint Inhibitors.<\/p>\n

\n About GeoVax<\/strong>\n <\/p>\n

GeoVax Labs, Inc. is a clinical-stage biotechnology company developing novel therapies and vaccines for solid tumor cancers and many of the world\u2019s most threatening infectious diseases. The company\u2019s lead program in oncology is a novel oncolytic solid tumor gene-directed therapy, Gedeptin\u00ae<\/sup>, presently in a multicenter Phase 1\/2 clinical trial for advanced head and neck cancers. GeoVax\u2019s lead infectious disease candidate is GEO-CM04S1, a next-generation COVID-19 vaccine targeting high-risk immunocompromised patient populations. Currently in two Phase 2 clinical trials, GEO-CM04S1 is being evaluated as a COVID-19 vaccine for immunocompromised patients such as those suffering from hematologic cancers and other patient populations for whom the current authorized COVID-19 vaccines are insufficient. In addition, GEO-CM04S1 is in a Phase 2 clinical trial evaluating the vaccine as a more robust, durable COVID-19 booster among healthy patients who previously received the mRNA vaccines. GeoVax has a leadership team who have driven significant value creation across multiple life science companies over the past several decades. For more information, visit our website: www.geovax.com.<\/p>\n

\n Forward-Looking Statements<\/em>\n <\/p>\n

\n This release contains forward-looking statements regarding GeoVax\u2019s business plans. The words \u201cbelieve,\u201d \u201clook forward to,\u201d \u201cmay,\u201d \u201cestimate,\u201d \u201ccontinue,\u201d \u201canticipate,\u201d \u201cintend,\u201d \u201cshould,\u201d \u201cplan,\u201d \u201ccould,\u201d \u201ctarget,\u201d \u201cpotential,\u201d \u201cis likely,\u201d \u201cwill,\u201d \u201cexpect\u201d and similar expressions, as they relate to us, are intended to identify forward-looking statements. We have based these forward-looking statements largely on our current expectations and projections about future events and financial trends that we believe may affect our financial condition, results of operations, business strategy and financial needs. Actual results may differ materially from those included in these statements due to a variety of factors, including whether: GeoVax is able to obtain acceptable results from ongoing or future clinical trials of its investigational products, GeoVax\u2019s immuno-oncology products and preventative vaccines can provoke the desired responses, and those products or vaccines can be used effectively, GeoVax\u2019s viral vector technology adequately amplifies immune responses to cancer antigens, GeoVax can develop and manufacture its immuno-oncology products and preventative vaccines with the desired characteristics in a timely manner, GeoVax\u2019s immuno-oncology products and preventative vaccines will be safe for human use, GeoVax\u2019s vaccines will effectively prevent targeted infections in humans, GeoVax\u2019s immuno-oncology products and preventative vaccines will receive regulatory approvals necessary to be licensed and marketed, GeoVax raises required capital to complete development, there is development of competitive products that may be more effective or easier to use than GeoVax\u2019s products, GeoVax will be able to enter into favorable manufacturing and distribution agreements, and other factors, over which GeoVax has no control. <\/em>\n <\/p>\n

\n Further information on our risk factors is contained in our periodic reports on Form 10-Q and Form 10-K that we have filed and will file with the SEC. Any forward-looking statement made by us herein speaks only as of the date on which it is made. Factors or events that could cause our actual results to differ may emerge from time to time, and it is not possible for us to predict all of them. We undertake no obligation to publicly update any forward-looking statement, whether <\/em>
\n as a result of<\/em>
\n new information, future developments or otherwise, except as may be required by law.\u00a0<\/em>\n <\/p>\n

\n Investor Relations Contact:<\/strong>
\n
Rich Cockrell
CG Capital
404-736-3838
govx@cg.capital<\/u><\/a><\/p>\n

\n Media Contact:<\/strong>
\n
Susan Roberts
sr@roberts-communications.com<\/u><\/a>
202-779-0929<\/p>\n<\/p>\n


\n
\n \n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

ATLANTA, GA, June 28, 2023 (GLOBE NEWSWIRE) — via NewMediaWire \u2013 GeoVax Labs, Inc. (Nasdaq: GOVX), a biotechnology company developing immunotherapies and vaccines against cancers and infectious diseases, today announced that an abstract regarding GeoVax\u2019s gene therapy candidate, Gedeptin\u00ae, has been selected for poster presentation at the American Association for Cancer Research (AACR) and the American Head and Neck Society (AHNS) joint Head and Neck Cancer Conference, being held from July 7-8, 2023 at the Palais des congr\u00e8s de Montr\u00e9al in Montr\u00e9al, QC, Canada. Presentation Details: Abstract Title: Phase 1\/ 2 study of Ad\/PNP with fludarabine for the treatment of head neck squamous cell carcinoma (HNSCC) \u00a0 Abstract Authors: A. Dimitrios Colevas1, Eric J. Sorscher2, William Parker3, Roan Courtney Raymundo1, … <\/p>\n

Continue reading “GeoVax Announces Gedeptin\u00ae Presentation at the AACR-AHNS Head and Neck Cancer Conference”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-766682","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nGeoVax Announces Gedeptin\u00ae Presentation at the AACR-AHNS Head and Neck Cancer Conference - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/geovax-announces-gedeptin-presentation-at-the-aacr-ahns-head-and-neck-cancer-conference\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"GeoVax Announces Gedeptin\u00ae Presentation at the AACR-AHNS Head and Neck Cancer Conference - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"ATLANTA, GA, June 28, 2023 (GLOBE NEWSWIRE) — via NewMediaWire \u2013 GeoVax Labs, Inc. 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(Nasdaq: GOVX), a biotechnology company developing immunotherapies and vaccines against cancers and infectious diseases, today announced that an abstract regarding GeoVax\u2019s gene therapy candidate, Gedeptin\u00ae, has been selected for poster presentation at the American Association for Cancer Research (AACR) and the American Head and Neck Society (AHNS) joint Head and Neck Cancer Conference, being held from July 7-8, 2023 at the Palais des congr\u00e8s de Montr\u00e9al in Montr\u00e9al, QC, Canada. Presentation Details: Abstract Title: Phase 1\/ 2 study of Ad\/PNP with fludarabine for the treatment of head neck squamous cell carcinoma (HNSCC) \u00a0 Abstract Authors: A. Dimitrios Colevas1, Eric J. 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