{"id":762895,"date":"2023-06-12T07:03:19","date_gmt":"2023-06-12T11:03:19","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/"},"modified":"2023-06-12T07:03:19","modified_gmt":"2023-06-12T11:03:19","slug":"castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/","title":{"rendered":"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx<sup>\u00ae<\/sup>-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging<\/b><\/p>\n<p class=\"bwalignc\"><i>Data shared during the 2023 Fall Clinical Dermatology Conference for PAs &amp; NPs<sup>\u00ae<\/sup><\/i><\/p>\n<p>FRIENDSWOOD, Texas&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nCastle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced new data demonstrating the ability of the DecisionDx<sup>\u00ae<\/sup>-SCC test to identify cutaneous squamous cell carcinoma (cSCC) tumors at a biologically high risk of metastasis in a subset of patients considered to be at a low risk of metastasis by traditional staging (i.e., patients with T1 tumors under the American Joint Committee on Cancer Eighth Edition (AJCC8) and Brigham and Women\u2019s Hospital (BWH) staging systems). The data was shared in a poster, titled \u201cThe 40-gene expression profile (40-GEP) test allows for an improved prognostication of the likelihood of metastasis in patients with T1 cutaneous squamous cell carcinoma (cSCC) with high-risk factors,\u201d during the recent 2023 Fall Clinical Dermatology Conference for PAs &amp; NPs<sup>\u00ae<\/sup>.<\/p>\n<p>\n\u201cTraditional staging, which includes solely tumor characteristics, only tells part of the story and leaves out a very critical piece of the plot, the biology of an individual patient\u2019s tumor, which can provide greater insight into each patient\u2019s unique metastatic propensity,\u201d said Ally-Khan Somani, M.D., Ph.D., board-certified dermatologist, Mohs micrographic surgeon and director of Dermatologic Surgery &amp; Cutaneous Oncology Division at the Indiana University School of Medicine in Indianapolis. \u201cBy estimating a cSCC patient\u2019s personal risk of metastasis, the DecisionDx-SCC test has proven to elevate the narrative, which can lead to more informed, pertinent risk-aligned treatment decisions that can help improve outcomes.\u201d<\/p>\n<p>\nIn the study, the DecisionDx-SCC test was able to significantly stratify three-year metastasis free survival rates within the AJCC8 and BWH T1 populations of the cSCC cohort. Approximately 70% of the AJCC8- and BWH-staged T1 tumors that metastasized were identified as being biologically high-risk by the DecisionDx-SCC test. This data supports the ability of the test to improve risk assessments based on staging alone, enabling clinicians and patients to make more risk-appropriate surveillance and treatment decisions.<\/p>\n<p>\nCastle\u2019s poster will be published in <i>SKIN, The Journal of Cutaneous Medicine<\/i><sup>\u00ae<\/sup> (<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.jofskin.org&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=www.jofskin.org&amp;index=1&amp;md5=1dc6a219c0bd0705e311d4fe755a24f9\">www.jofskin.org<\/a>), and may also be viewed <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fcastlebiosciences.com%2Fwp-content%2Fuploads%2F2023%2F06%2FSC_01_0100-Fall-Clinical-NPPA-2023-T1-subset_FINAL.pdf&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=here&amp;index=2&amp;md5=466da4c87f58db0d631d448e0ce7f6cb\">here<\/a>.<\/p>\n<p><b>About DecisionDx<sup>\u00ae<\/sup>-SCC<\/b><\/p>\n<p>\nDecisionDx-SCC is a 40-gene expression profile test that uses an individual patient\u2019s tumor biology to predict individual risk of cutaneous squamous cell carcinoma metastasis for patients with one or more risk factors. The test result, in which patients are stratified into a Class 1 (low), Class 2A (moderate) or Class 2B (high) risk category, predicts individual metastatic risk to inform risk-appropriate management.<\/p>\n<p>\nPeer-reviewed publications have demonstrated that DecisionDx-SCC is an independent predictor of metastatic risk and that integrating DecisionDx-SCC with current prognostic methods can add positive predictive value to clinician decisions regarding staging and management. More information about the disease and test can be found at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.castletestinfo.com%2F&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=www.CastleTestInfo.com.&amp;index=3&amp;md5=2da173cf30c92519a60748a56e8dca74\">www.CastleTestInfo.com.<\/a><\/p>\n<p><b>About Castle Biosciences<\/b><\/p>\n<p>\nCastle Biosciences (Nasdaq: CSTL) is a leading diagnostics company improving health through innovative tests that guide patient care. The Company aims to transform disease management by keeping people first: patients, clinicians, employees and investors.<\/p>\n<p>\nCastle\u2019s current portfolio consists of tests for skin cancers, uveal melanoma, Barrett\u2019s esophagus and mental health conditions. Additionally, the Company has active research and development programs for tests in other diseases with high clinical need, including its test in development to predict systemic therapy response in patients with moderate-to-severe psoriasis, atopic dermatitis and related conditions. To learn more, please visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.CastleBiosciences.com&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=www.CastleBiosciences.com&amp;index=4&amp;md5=44055603ef344f67b730fb0613ed1e44\">www.CastleBiosciences.com<\/a> and connect with us on <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fcompany%2Fcastle-biosciences-inc-%2F&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=5&amp;md5=8a38e634c079c5a61ca550e477ca8475\">LinkedIn<\/a>, <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.facebook.com%2Fcastlebiosciences%2F&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=Facebook&amp;index=6&amp;md5=e648d120091f8c66d14d1337f6ba3de2\">Facebook<\/a>, <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Fcastlebio%3Flang%3Den&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=Twitter&amp;index=7&amp;md5=06f57c626e11ea5820c0e7240c9acb17\">Twitter<\/a> and <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.instagram.com%2Fcastlebiosciences%2F&amp;esheet=53418344&amp;newsitemid=20230612035931&amp;lan=en-US&amp;anchor=Instagram&amp;index=8&amp;md5=e02a2abb3d6069f5136ef895d15b20a8\">Instagram<\/a>.<\/p>\n<p>\nDecisionDx-Melanoma, DecisionDx-CM<i>Seq<\/i>, DecisionDx-SCC, MyPath Melanoma, DecisionDx-UM, DecisionDx-PRAME, DecisionDx-UM<i>Seq<\/i>, TissueCypher and IDgenetix are trademarks of Castle Biosciences, Inc.<\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p><i>This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to the \u201csafe harbor\u201d created by those sections. These forward-looking statements include, but are not limited to, statements concerning: the potential of DecisionDx-SCC to (i) provide greater insight into each patient\u2019s unique metastatic propensity and (ii) lead to more informed, pertinent risk-aligned treatment decisions that can help improve outcomes. The words \u201ccan,\u201d \u201cpotential\u201d and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. We may not actually achieve the plans, intentions or expectations disclosed in our forward-looking statements, and you should not place undue reliance on our forward-looking statements. Actual results or events could differ materially from the plans, intentions and expectations disclosed in the forward-looking statements that we make. These forward-looking statements involve risks and uncertainties that could cause our actual results to differ materially from those in the forward-looking statements, including, without limitation: subsequent study or trial results and findings may contradict earlier study or trial results and findings or may not support the results obtained in this study, including with respect to the discussion of DecisionDx-SCC in this press release; actual application of our tests may not provide the aforementioned benefits to patients; and the risks set forth under the heading \u201cRisk Factors\u201d in our Quarterly Report on Form 10-Q for the three months ended March 31, 2023, and in our other filings with the SEC. The forward-looking statements are applicable only as of the date on which they are made, and we do not assume any obligation to update any forward-looking statements, except as may be required by law.<\/i><\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230612035931r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20230612035931\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20230612035931\/en\/<\/a><\/span><\/p>\n<p><b>Investor Contact:<br \/>\n<\/b><br \/>Camilla Zuckero<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:czuckero@castlebiosciences.com\">czuckero@castlebiosciences.com<\/a><\/p>\n<p><b>Media Contact:<br \/>\n<\/b><br \/>Allison Marshall<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:amarshall@castlebiosciences.com\">amarshall@castlebiosciences.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> United States North America Texas<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Science Other Science Biotechnology Research Oncology Health Clinical Trials Other Health<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230612035931\/en\/1815936\/3\/CastleLogo2Color.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging Data shared during the 2023 Fall Clinical Dermatology Conference for PAs &amp; NPs\u00ae FRIENDSWOOD, Texas&#8211;(BUSINESS WIRE)&#8211; Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced new data demonstrating the ability of the DecisionDx\u00ae-SCC test to identify cutaneous squamous cell carcinoma (cSCC) tumors at a biologically high risk of metastasis in a subset of patients considered to be at a low risk of metastasis by traditional staging (i.e., patients with T1 tumors under the American Joint Committee on Cancer Eighth Edition (AJCC8) and &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-762895","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging Data shared during the 2023 Fall Clinical Dermatology Conference for PAs &amp; NPs\u00ae FRIENDSWOOD, Texas&#8211;(BUSINESS WIRE)&#8211; Castle Biosciences, Inc. (Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced new data demonstrating the ability of the DecisionDx\u00ae-SCC test to identify cutaneous squamous cell carcinoma (cSCC) tumors at a biologically high risk of metastasis in a subset of patients considered to be at a low risk of metastasis by traditional staging (i.e., patients with T1 tumors under the American Joint Committee on Cancer Eighth Edition (AJCC8) and &hellip; Continue reading &quot;Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-12T11:03:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230612035931r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging\",\"datePublished\":\"2023-06-12T11:03:19+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/\"},\"wordCount\":998,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230612035931r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\\\/\",\"name\":\"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging - 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(Nasdaq: CSTL), a company improving health through innovative tests that guide patient care, today announced new data demonstrating the ability of the DecisionDx\u00ae-SCC test to identify cutaneous squamous cell carcinoma (cSCC) tumors at a biologically high risk of metastasis in a subset of patients considered to be at a low risk of metastasis by traditional staging (i.e., patients with T1 tumors under the American Joint Committee on Cancer Eighth Edition (AJCC8) and &hellip; Continue reading \"Castle Biosciences Presents New Data Demonstrating the Ability of DecisionDx\u00ae-SCC to Identify Tumors Likely to Metastasize in Patients with Cutaneous Squamous Cell Carcinoma Deemed Low Risk by Traditional Staging\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/castle-biosciences-presents-new-data-demonstrating-the-ability-of-decisiondx-scc-to-identify-tumors-likely-to-metastasize-in-patients-with-cutaneous-squamous-cell-carcinoma-deemed-low-risk-by-tr\/","og_site_name":"Market 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