{"id":762380,"date":"2023-06-08T07:04:36","date_gmt":"2023-06-08T11:04:36","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/"},"modified":"2023-06-08T07:04:36","modified_gmt":"2023-06-08T11:04:36","slug":"biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/","title":{"rendered":"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan"},"content":{"rendered":"<div class=\"mw_release\">\n<p>SUNNYVALE, Calif., June  08, 2023  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Edq5V6EhJpwugKn70ImMzsBHJzHX-agIUgtRNvJs1PprT-e65WFRrHfib4MuG14PChtb83uF2OffmwlxFU3wpO7RaRhsOIhYLwAIjjuNLTv_1JWYQegBQOr0KCwW0ntBaVz8-d9vL52Y-vBLOFPBmt-HQCtNHV8TnePHsaULXAXnhb3yCBFk1x_Q2T0wFSIRp465dNekcbS21J6581Xh0534MhNkxdlmyAcOdQFjfbEL4BXwvAPORiCMtIrVBV8KtwxG8RNIgCB-zyZ-Wtif9X-l1ECGGYE0ThkZXn04xHPaGxJUP-cN5Bm328w4dH-kcCVsMn6lq1VLvXHHDYjXtcAPN03uCXuLoql0tChXLBLLuxrxSB4sxzzah_-J3L0aHckvHcZvNC96Efq-Hj4aNi1XW9-bQKuXRU8UwTQLf4c=\" rel=\"nofollow noopener\" target=\"_blank\"><u>BioCardia\u00ae, Inc.<\/u><\/a>\u00a0[Nasdaq: BCDA], a company focused on cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases today announces that the Japan Patent Office has granted Patent No: JP7282649B2 titled \u201cRadial and Transendocardial Delivery Catheter\u201d with a patent term that will expire on September 30, 2034.\u00a0\u00a0<\/p>\n<p>This patent describes interventional biotherapeutic delivery catheters to deliver biologics to specific target sites from within the heart chamber. The allowed claims cover BioCardia\u2019s helical needle tipped catheter technology platform in existing products and in future products in active development with enhanced features.<\/p>\n<p>\u201cOur Helix\u2122 minimally invasive biotherapeutic delivery platform enables the successful development of cell and gene-based therapies for the heart,\u201d said Dr. Peter Altman, BioCardia CEO. \u201cThe Helix platform underlies BioCardia\u2019s cell therapy clinical programs and is actively enabling important therapeutic strategies for select partners. This recent patent issuance provides additional protection to our technology and product offerings in Japan. Developers of cardiac cell-based therapies, including BioCardia, are seeking first approvals to begin marketing for the treatment of heart failure in Japan. A cardiac cell therapy has already been approved in Japan, but it requires surgical open chest delivery, whereas the Helix catheter system delivers the cell therapies it enables in a minimally invasive fashion.\u201d<\/p>\n<p>The Helix transendocardial biotherapeutic delivery system has a small helical needle which engages the heart tissue and is stable within the dynamic beating heart. The platform is believed to be the safest, easiest, and most efficient way to locally deliver biotherapeutics to the heart. It has demonstrated increased effective dosing by three-fold over surgical access intramyocardial biotherapeutic delivery<sup>1<\/sup> and has demonstrated enhanced procedural safety in its clinical experience<sup>2<\/sup>.<\/p>\n<p>BioCardia\u2019s cardiac biotherapeutics under development include: BCDA-01, the pivotal CardiAMP<sup>\u00ae<\/sup> autologous cell therapy in ischemic heart failure with next DSMB scheduled for July 12, 2023, BCDA-02, the pivotal CardiAMP<sup>\u00ae<\/sup> autologous cell therapy in chronic myocardial ischemia expected to complete its roll in cohort this year, and BCDA-03, the CardiALLO\u2122 allogeneic mesenchymal cell therapy which is expected to treat first patients soon.<\/p>\n<p>\n        <strong>About BioCardia<sup>\u00ae<\/sup><\/strong>\n      <\/p>\n<p>BioCardia, Inc., headquartered in Sunnyvale, California, is a developer of two biotherapeutic platforms \u2013 the CardiAMP\u00a0autologous bone marrow derived mononuclear cell therapy for cardiovascular indications, and the NK1R+ allogeneic bone marrow derived mesenchymal stem cell therapies for cardiovascular and pulmonary diseases.\u00a0 These platforms underlie four product candidates, each with the potential to meaningfully benefit millions of patients. Three of these investigational therapies are enabled by the Company\u2019s proprietary biotherapeutic delivery platforms, which the Company also selectively licenses to other biotherapeutic development firms.<\/p>\n<p>\n        <strong>Forward Looking Statements:<\/strong>\n      <\/p>\n<p>This press release contains forward-looking statements that are subject to many risks and uncertainties. Forward-looking statements include, among other things, references to the Company\u2019s investigational product candidates, efforts in having cell therapies initially approved in Japan, the scheduled DSMB review for BCDA-01, the completion of the roll in cohort for BCDA-02, and the treatment of first patients with BCDA-03.\u00a0 These forward-looking statements are made as of the date of this press release, and BioCardia assumes no obligation to update the forward-looking statements.<\/p>\n<p>We may use terms such as \u201cbelieves,\u201d \u201cestimates,\u201d \u201canticipates,\u201d \u201cexpects,\u201d \u201cplans,\u201d \u201cintends,\u201d \u201cmay,\u201d \u201ccould,\u201d \u201cmight,\u201d \u201cwill,\u201d \u201cshould,\u201d \u201capproximately\u201d or other words that convey the uncertainty of future events or outcomes to identify these forward-looking statements. Although we believe that we have a reasonable basis for each forward-looking statement contained herein, we caution you that forward-looking statements are not guarantees of future performance and that our actual results may differ materially from the forward-looking statements contained in this press release. As a result of these factors, we cannot assure you that the forward-looking statements in this press release will prove to be accurate.\u00a0 Additional factors that could materially affect actual results can be found in BioCardia\u2019s Form 10-K filed with the Securities and Exchange Commission on March 29, 2023, under the caption titled \u201cRisk Factors.\u201d BioCardia expressly disclaims any intent or obligation to update these forward-looking statements, except as required by law.<\/p>\n<p>(1)\u00a0\u00a0\u00a0Mitsutake Y, Pyum WB, Rouy D, Wong Po Foo C, Stertzer SH, Altman P, Ikeno F. Improvement of local cell delivery using Helix Transendocardial Delivery Catheter in a porcine heart, Int Heart J. 2017.\u00a0<\/p>\n<p>(2)\u00a0\u00a0\u00a0Raval AN and Pepine CJ. Clinical Safety Profile of Transendocardial Catheter Injection Systems: A Plea for Uniform Reporting, Cardiovasc Revasc Med, 2021.<\/p>\n<p>\n        <strong>Media Contact<\/strong>:<br \/>Anne Laluc, Marketing<br \/>Email:\u00a0info@biocardia.com<br \/>Phone: 650-226-0120<\/p>\n<p>\n        <strong>Investor Contact:<\/strong><br \/>\n        <br \/>David McClung, Chief Financial Officer<br \/>Email:\u00a0investors@biocardia.com<br \/>Phone: 650-226-0120<\/p>\n<p>      <img decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODg1NDU0NSM1NjM3MTU2IzIwMTk4MTk=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" src=\"https:\/\/ml.globenewswire.com\/media\/NGI5YzA5MDAtNmE1Mi00YjVmLWFlZDEtYjFiMDkwOTYzYWViLTEwMzEzOTE=\/tiny\/BioCardia-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>SUNNYVALE, Calif., June 08, 2023 (GLOBE NEWSWIRE) &#8212; BioCardia\u00ae, Inc.\u00a0[Nasdaq: BCDA], a company focused on cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases today announces that the Japan Patent Office has granted Patent No: JP7282649B2 titled \u201cRadial and Transendocardial Delivery Catheter\u201d with a patent term that will expire on September 30, 2034.\u00a0\u00a0 This patent describes interventional biotherapeutic delivery catheters to deliver biologics to specific target sites from within the heart chamber. The allowed claims cover BioCardia\u2019s helical needle tipped catheter technology platform in existing products and in future products in active development with enhanced features. \u201cOur Helix\u2122 minimally invasive biotherapeutic delivery platform enables the successful development of cell and gene-based therapies for the heart,\u201d said Dr. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-762380","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"SUNNYVALE, Calif., June 08, 2023 (GLOBE NEWSWIRE) &#8212; BioCardia\u00ae, Inc.\u00a0[Nasdaq: BCDA], a company focused on cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases today announces that the Japan Patent Office has granted Patent No: JP7282649B2 titled \u201cRadial and Transendocardial Delivery Catheter\u201d with a patent term that will expire on September 30, 2034.\u00a0\u00a0 This patent describes interventional biotherapeutic delivery catheters to deliver biologics to specific target sites from within the heart chamber. The allowed claims cover BioCardia\u2019s helical needle tipped catheter technology platform in existing products and in future products in active development with enhanced features. \u201cOur Helix\u2122 minimally invasive biotherapeutic delivery platform enables the successful development of cell and gene-based therapies for the heart,\u201d said Dr. &hellip; Continue reading &quot;BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-06-08T11:04:36+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODg1NDU0NSM1NjM3MTU2IzIwMTk4MTk=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan\",\"datePublished\":\"2023-06-08T11:04:36+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/\"},\"wordCount\":748,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODg1NDU0NSM1NjM3MTU2IzIwMTk4MTk=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\\\/\",\"name\":\"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/","og_locale":"en_US","og_type":"article","og_title":"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan - Market Newsdesk","og_description":"SUNNYVALE, Calif., June 08, 2023 (GLOBE NEWSWIRE) &#8212; BioCardia\u00ae, Inc.\u00a0[Nasdaq: BCDA], a company focused on cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases today announces that the Japan Patent Office has granted Patent No: JP7282649B2 titled \u201cRadial and Transendocardial Delivery Catheter\u201d with a patent term that will expire on September 30, 2034.\u00a0\u00a0 This patent describes interventional biotherapeutic delivery catheters to deliver biologics to specific target sites from within the heart chamber. The allowed claims cover BioCardia\u2019s helical needle tipped catheter technology platform in existing products and in future products in active development with enhanced features. \u201cOur Helix\u2122 minimally invasive biotherapeutic delivery platform enables the successful development of cell and gene-based therapies for the heart,\u201d said Dr. &hellip; Continue reading \"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/","og_site_name":"Market Newsdesk","article_published_time":"2023-06-08T11:04:36+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODg1NDU0NSM1NjM3MTU2IzIwMTk4MTk=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan","datePublished":"2023-06-08T11:04:36+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/"},"wordCount":748,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODg1NDU0NSM1NjM3MTU2IzIwMTk4MTk=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/biocardia-announces-helix-biotherapeutic-delivery-patent-issuance-in-japan\/","name":"BioCardia Announces Helix\u2122 Biotherapeutic Delivery Patent Issuance in Japan - 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