{"id":758594,"date":"2023-05-12T17:30:12","date_gmt":"2023-05-12T21:30:12","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/"},"modified":"2023-05-12T17:30:12","modified_gmt":"2023-05-12T21:30:12","slug":"precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/","title":{"rendered":"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Precision BioSciences Announces Publication of its Preclinical <i>In Vivo<\/i> Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26<sup>th<\/sup> Annual Meeting<\/b><\/p>\n<p class=\"bwalignc\"><i>Late-Breaking Abstract Demonstrates Capabilities of ARCUS for Large Gene Excision In Vivo<\/i><\/p>\n<p>DURHAM, N.C.&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nPrecision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS\u00ae-based <i>ex vivo<\/i> allogeneic CAR T and <i>in vivo<\/i> gene editing therapies, today announced that its late-breaking abstract presenting preclinical <i>in vivo<\/i> gene editing data for its PBGENE-DMD program, being developed for the potential treatment of Duchenne muscular dystrophy (DMD), is available through the American Society of Gene &amp; Cell Therapy (ASGCT) 26<sup>th<\/sup> Annual Meeting website at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fannualmeeting.asgct.org%2Fabstracts%2Fabstract-details%3FabstractId%3D15227&amp;esheet=53399817&amp;newsitemid=20230512005427&amp;lan=en-US&amp;anchor=https%3A%2F%2Fannualmeeting.asgct.org%2Fabstracts%2Fabstract-details%3FabstractId%3D15227&amp;index=1&amp;md5=54780b352877d3b1538bdb7e8f71bcce\">https:\/\/annualmeeting.asgct.org\/abstracts\/abstract-details?abstractId=15227<\/a>.<\/p>\n<p>\nAn oral presentation, <i>ARCUS-Mediated Excision of the \u201cHot Spot\u201d Region of the Human Dystrophin Gene for the Treatment of Duchenne Muscular Dystrophy (DMD)<\/i>, will be presented as part of the Late-breaking Abstracts 2 Session on May 19, 2023.<\/p>\n<p><b>About ARCUS<br \/>\n<br \/><\/b>ARCUS is a proprietary genome editing technology discovered and developed by scientists at Precision BioSciences. It uses sequence-specific DNA-cutting enzymes, or nucleases, that are designed to either insert (knock-in), excise (knock-out), or repair DNA of living cells and organisms. ARCUS is based on a naturally occurring genome editing enzyme, I-CreI, that evolved in the algae Chlamydomonas reinhardtii to make highly specific cuts in cellular DNA and stimulate gene insertion at the cut site by homologous recombination. Precision&#8217;s platform and products are protected by a comprehensive portfolio including nearly 100 patents to date.<\/p>\n<p><b>About DMD<br \/>\n<br \/><\/b>DMD is a genetic disorder associated with mutations in the dystrophin gene that prevent production of the dystrophin protein. Dystrophin stabilizes the cell membrane during muscle contraction to prevent damage, and the absence of intact dystrophin protein leads to inflammation, fibrosis, and progressive loss of muscle function and mass. Over time, children with DMD will develop problems walking and breathing, eventually leading to death in the second or third decade of life due to progressive cardiomyopathy and respiratory insufficiency. DMD occurs in 1 in 3,500 to 5,000 male births, and currently there are limited approved therapies available for patients.<\/p>\n<p><b>About Precision BioSciences, Inc.<br \/>\n<br \/><\/b>Precision BioSciences, Inc. is a clinical stage biotechnology company dedicated to improving life (DTIL) with its novel and proprietary ARCUS\u00ae genome editing platform. ARCUS is a highly precise and versatile genome editing platform that was designed with therapeutic safety, delivery, and control in mind. Using ARCUS, the Company\u2019s pipeline consists of several <i>in vivo<\/i> gene editing candidates designed to cure genetic and infectious diseases where no adequate treatments exist and multiple <i>ex vivo<\/i> clinical candidates. For more information about Precision BioSciences, please visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.precisionbiosciences.com&amp;esheet=53399817&amp;newsitemid=20230512005427&amp;lan=en-US&amp;anchor=www.precisionbiosciences.com&amp;index=2&amp;md5=2919a11200892d6e2c10d817d894df86\">www.precisionbiosciences.com<\/a>.<\/p>\n<p><b>Forward-Looking Statements<br \/>\n<br \/><\/b>This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this press release that do not relate to matters of historical fact should be considered forward-looking statements, including, without limitation, statements regarding expected conference participation and disclosure of preclinical data, the clinical development, nomination, and goals of our PBGENE-DMD program, and therapeutic potential of an ARCUS gene editing approach for the treatment of DMD. In some cases, you can identify forward-looking statements by terms such as \u201caim,\u201d \u201canticipate,\u201d \u201capproach,\u201d \u201cbelieve,\u201d \u201ccontemplate,\u201d \u201ccould,\u201d \u201cestimate,\u201d \u201cexpect,\u201d \u201cgoal,\u201d \u201cintend,\u201d \u201clook,\u201d \u201cmay,\u201d \u201cmission,\u201d \u201cplan,\u201d \u201cpossible,\u201d \u201cpotential,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cpursue,\u201d \u201cshould,\u201d \u201ctarget,\u201d \u201cwill,\u201d \u201cwould,\u201d or the negative thereof and similar words and expressions.<\/p>\n<p>\nForward-looking statements are based on management\u2019s current expectations, beliefs and assumptions and on information currently available to us. Such statements are neither promises nor guarantees, but involve a number of known and unknown risks, uncertainties and assumptions, and actual results may differ materially from those expressed or implied in the forward-looking statements due to various important factors, including, but not limited to, the important factors discussed under the caption \u201cRisk Factors\u201d in our Quarterly Report on Form 10-Q for the quarterly period ended March 31, 2023, as any such factors may be updated from time to time in our other filings with the SEC, which are accessible on the SEC\u2019s website at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sec.gov&amp;esheet=53399817&amp;newsitemid=20230512005427&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=3&amp;md5=bdfdd33e2e35426ca9b1fdd8b987430e\">www.sec.gov<\/a> and the Investors page of our website under SEC Filings at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Finvestor.precisionbiosciences.com%2F&amp;esheet=53399817&amp;newsitemid=20230512005427&amp;lan=en-US&amp;anchor=investor.precisionbiosciences.com&amp;index=4&amp;md5=6f6fd2675e56d8c66a83439ce4578b06\">investor.precisionbiosciences.com<\/a>.<\/p>\n<p>\nAll forward-looking statements speak only as of the date of this press release and, except as required by applicable law, we have no obligation to update or revise any forward-looking statements contained herein, whether as a result of any new information, future events, changed circumstances or otherwise.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230512005427r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20230512005427\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20230512005427\/en\/<\/a><\/span><\/p>\n<p><b>Investor and Media Contact:<br \/>\n<\/b><br \/>Mei Burris<br \/>\n<br \/>Director, Investor Relations and Finance<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:Mei.Burris@precisionbiosciences.com\">Mei.Burris@precisionbiosciences.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> North Carolina United States North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Health General Health Pharmaceutical Oncology Other Science Research Infectious Diseases Genetics Science Clinical Trials<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230512005427\/en\/593587\/3\/Precision_BioSciences_logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting Late-Breaking Abstract Demonstrates Capabilities of ARCUS for Large Gene Excision In Vivo DURHAM, N.C.&#8211;(BUSINESS WIRE)&#8211; Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS\u00ae-based ex vivo allogeneic CAR T and in vivo gene editing therapies, today announced that its late-breaking abstract presenting preclinical in vivo gene editing data for its PBGENE-DMD program, being developed for the potential treatment of Duchenne muscular dystrophy (DMD), is available through the American Society of Gene &amp; Cell Therapy (ASGCT) 26th Annual Meeting website at https:\/\/annualmeeting.asgct.org\/abstracts\/abstract-details?abstractId=15227. An oral presentation, ARCUS-Mediated Excision of &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-758594","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting Late-Breaking Abstract Demonstrates Capabilities of ARCUS for Large Gene Excision In Vivo DURHAM, N.C.&#8211;(BUSINESS WIRE)&#8211; Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS\u00ae-based ex vivo allogeneic CAR T and in vivo gene editing therapies, today announced that its late-breaking abstract presenting preclinical in vivo gene editing data for its PBGENE-DMD program, being developed for the potential treatment of Duchenne muscular dystrophy (DMD), is available through the American Society of Gene &amp; Cell Therapy (ASGCT) 26th Annual Meeting website at https:\/\/annualmeeting.asgct.org\/abstracts\/abstract-details?abstractId=15227. An oral presentation, ARCUS-Mediated Excision of &hellip; Continue reading &quot;Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-05-12T21:30:12+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230512005427r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; 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Precision BioSciences, Inc. (Nasdaq: DTIL), a clinical stage gene editing company developing ARCUS\u00ae-based ex vivo allogeneic CAR T and in vivo gene editing therapies, today announced that its late-breaking abstract presenting preclinical in vivo gene editing data for its PBGENE-DMD program, being developed for the potential treatment of Duchenne muscular dystrophy (DMD), is available through the American Society of Gene &amp; Cell Therapy (ASGCT) 26th Annual Meeting website at https:\/\/annualmeeting.asgct.org\/abstracts\/abstract-details?abstractId=15227. An oral presentation, ARCUS-Mediated Excision of &hellip; Continue reading \"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; Cell Therapy 26th Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/","og_site_name":"Market Newsdesk","article_published_time":"2023-05-12T21:30:12+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230512005427r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/precision-biosciences-announces-publication-of-its-preclinical-in-vivo-gene-editing-abstract-on-duchenne-muscular-dystrophy-program-for-the-american-society-of-gene-cell-therapy-26th-annual-meet\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Precision BioSciences Announces Publication of its Preclinical In Vivo Gene Editing Abstract on Duchenne Muscular Dystrophy Program for the American Society of Gene &amp; 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