{"id":749101,"date":"2023-04-19T09:21:54","date_gmt":"2023-04-19T13:21:54","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/"},"modified":"2023-04-19T09:21:54","modified_gmt":"2023-04-19T13:21:54","slug":"data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/","title":{"rendered":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdisc { list-style-type: disc }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development<\/b><\/p>\n<p class=\"bwalignc\"><i>&#8211; <\/i><i>Includes recent advancements from precision designed compounds<\/i><i> &#8211;<\/i><\/p>\n<p class=\"bwalignc\"><i>&#8211; <\/i><i>Functional personalised medicine platform unveiling unique adenosine biomarker to enrich for patients more likely to respond to treatment <\/i><i>&#8211;<\/i><\/p>\n<p>OXFORD, England&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nExscientia plc (Nasdaq: EXAI) today announced four presentations at the American Association for Cancer Research (AACR) Annual Meeting 2023, being held from April 14-19, 2023 in Orlando, FL.<\/p>\n<p>\n\u201cWe\u2019re excited to further validate Exscientia\u2019s end-to-end approach of integrating outstanding science with cutting-edge AI-driven precision medicine and translational research capabilities,\u201d said Andrew Hopkins, D.Phil, founder and Chief Executive Officer of Exscientia. \u201cThe clinical and preclinical data showcased at AACR demonstrate how our approaches help not only efficiently design novel molecules, but also aim to differentiate them through superior properties and targeting the right patients to benefit from them. We look forward to continuing to develop our personalised medicine candidates with the goal of providing solutions to patients in need of effective treatment around the world.\u201d<\/p>\n<p><b>Poster Presentations<\/b><\/p>\n<p><b>Title: <\/b><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.exscientia.ai%2Fpresentations%3Futm_source%3DPR%26utm_medium%3Dtextlink%26utm_campaign%3DAACR23%26utm_term%3Dtransa2a%26utm_content%3Dposter&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=Identification+of+transcript+adenosine+fingerprint+to+enrich+for+A2AR+and+PD-1+inhibition+responders&amp;index=1&amp;md5=5a46a672a9f5f32a115b797e46df54ec\">Identification of transcript adenosine fingerprint to enrich for A<sub>2A<\/sub>R and PD-1 inhibition responders<br \/>\n<\/a><br \/><b>Session Title: <\/b>Biomarkers of Therapeutic Benefit 2<br \/>\n<br \/><b>Abstract Number: <\/b>#2151<br \/>\n<br \/><b>Date\/Time: <\/b>Monday, April 17 \/ 9:00 AM &#8211; 12:30 PM EDT<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nIn this poster, Exscientia reveals its internally and preclinically developed adenosine burden score (ABS; first revealed at the end of 2022) is based on B-cell biology and that EXS21546 (\u2018546), Exscientia\u2019s selective clinical stage A<sub>2A<\/sub>R antagonist, reverts effects of adenosine analogues <i>ex vivo<\/i> in patient tissue samples and other complex models<\/p>\n<\/li>\n<li>\nLeveraging proprietary data, it was determined that the ABS is inversely correlated with PD-1 expression pathways as well as published PD-1 enrichment scores. Analysis of public human and mouse data confirms an enrichment of ABS-high samples are among those less likely to respond to checkpoint inhibition<\/p>\n<\/li>\n<li>\nCurrent modelling in complex human blood samples shows that \u2018546 as well as an example dual A<sub>2A<\/sub>R and A<sub>2B<\/sub>R antagonist are both highly correlated in reversing effects of adenosine analogue <i>ex vivo<\/i><\/li>\n<\/ul>\n<p><b>Title: <\/b><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.exscientia.ai%2Fpresentations%3Futm_source%3DPR%26utm_medium%3Dtextlink%26utm_campaign%3DAACR23%26utm_term%3Dlsd1%26utm_content%3Dposter&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=Characterizing+antitumor+responses+to+EXS74539%2C+a+novel%2C+reversible+LSD1+inhibitor+with+potential+in+small-cell+lung+cancer&amp;index=2&amp;md5=dcd9444ef9e3d1f91a91ff37bc33f708\">Characterizing antitumor responses to EXS74539, a novel, reversible LSD1 inhibitor with potential in small-cell lung cancer<br \/>\n<\/a><br \/><b>Session Title: <\/b>Epigenetics<br \/>\n<br \/><b>Abstract Number: <\/b>#6290<br \/>\n<br \/><b>Date\/Time: <\/b>Wednesday, April 19 \/ 9:00 AM &#8211; 12:30 PM EDT<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nExscientia precision-designed EXS74539 (\u2018539), an LSD1 inhibitor with a differentiated profile combining reversibility and brain penetrance, to optimally target LSD1 in future oncology and haematology patient populations, including small-cell lung cancer (SCLC)<\/p>\n<\/li>\n<li>\nThe reversible mechanism-of-action combined with a shorter half-life may provide an opportunity to better manage on-target dose-limiting thrombocytopenia observed with other LSD1 inhibitors in development<\/p>\n<\/li>\n<li><i>In vitro<\/i> sensitivity analysis of small cell lung cancer (SCLC) cell line models to \u2018539 alone was shown to not sufficiently predict <i>in vivo<\/i> response; researchers believe that predicting<i> in vivo<\/i> tumour response to \u2018539 is critical to ensuring optimal use of the compound. Combining transcriptional and functional responses <i>in vitro, <\/i>however<i>,<\/i> may overcome this\n<\/li>\n<li>\nExscientia has identified genetic fingerprints which may function as markers of \u2018539 sensitivity, which are undergoing characterisation and validation in human SCLC patient samples<\/p>\n<\/li>\n<\/ul>\n<p><b>Title:<\/b><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.exscientia.ai%2Fpresentations%3Futm_source%3DPR%26utm_medium%3Dtextlink%26utm_campaign%3DAACR23%26utm_term%3DOVC%26utm_content%3Dposter&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=Discovering+novel+targetable+pathways+by+combining+functional+and+multi-omic+data+from+primary+ovarian+cancer+samples&amp;index=3&amp;md5=8cc7485c2288fdfbbdbb1fce4010119e\">Discovering novel targetable pathways by combining functional and multi-omic data from primary ovarian cancer samples<br \/>\n<\/a><br \/><b>Session Title:<\/b> Novel Targets and Pathways<br \/>\n<br \/><b>Abstract Number: <\/b>#4956<br \/>\n<br \/><b>Date\/Time: <\/b>Sunday, April 16 \/ 1:30 PM &#8211; 5:00 PM EDT<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nThis poster highlights the use of data generated with Exscientia\u2019s precision medicine platform in combination with its proprietary methodology for multi-omics and multi-modal dataset mapping. By better understanding disease function, these tools combined can be leveraged to improve patient outcomes by uncovering clinically relevant targets at the discovery stage<\/p>\n<\/li>\n<li>\nData collected from disease-relevant patient samples including single cell functional responses, transcriptomics, protein-protein interactions and known drug-to-target interaction landscapes are combined with the goal of understanding cancer targets in the context of known biology, thereby understanding the target&#8217;s function and relevance early on in development, instead of relying on single endpoints common in the industry<\/p>\n<\/li>\n<li>\nBy mapping single cell functional and multi-omics data at baseline and after perturbation of a complex primary model system, researchers uncovered the PI3K\/AKT\/mTOR pathway as a novel anticancer node in high grade serous ovarian cancer (HGSOC). The poster further defines tumour necrosis factor (TNF) induced apoptosis function of the nuclear factor kappa B (NF-\u043aB) pathway via TRAIL (TNF-related apoptosis-inducing ligand) as a promising focus area for HGSOC<\/p>\n<\/li>\n<\/ul>\n<p><b>Title: <\/b><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.exscientia.ai%2Fpatient-first-ai%3Futm_source%3DPR%26utm_medium%3Dtextlink%26utm_campaign%3DAACR23%26utm_term%3Dclina2a%26utm_content%3Dposter&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=Data+from+first-in-human+study+of+EXS21546%2C+an+A2A+receptor+antagonist%2C+now+progressing+into+Phase+1%2F2+in+RCC%2FNSCLC&amp;index=4&amp;md5=0c014d09c97604331c27bd78dedc01de\">Data from first-in-human study of EXS21546, an A<sub>2A<\/sub> receptor antagonist, now progressing into Phase 1\/2 in RCC\/NSCLC<br \/>\n<\/a><br \/><b>Session Title:<\/b> Phase I Clinical Trials in Progress<br \/>\n<br \/><b>Abstract Number: <\/b>#CT114<br \/>\n<br \/><b>Date\/Time: <\/b>Monday, April 17 \/ 1:30 PM &#8211; 5:00 PM EDT<\/p>\n<ul class=\"bwlistdisc\">\n<li>\n\u2018546 is the first AI-designed immuno-oncology candidate in the clinic. Phase 1 objectives were achieved in a healthy volunteer study, confirming pharmacokinetics, pharmacodynamics, safety, and tolerability of \u2018546, allowing selection of a starting dose for the ongoing IGNITE Phase 1\/2 study \u200b\u200bin combination with a PD-1 inhibitor in patients with relapsed\/refractory renal cell carcinoma (RCC) and non-small cell lung cancer (NSCLC)<\/p>\n<\/li>\n<li>\nThe poster highlights the IGNITE trial design, which is based on extensive simulations to enable the most efficient continuous reassessment method settings to predict and most accurately evaluate the anti-tumoural effect of \u2018546 in combination with checkpoint inhibition as well as any dose limiting toxicity<\/p>\n<\/li>\n<li>\nThe IGNITE trial will also provide clinical data to support Exscientia\u2019s patient enrichment biomarker strategy, using the ABS to identify patients with adenosine rich tumour microenvironments who may benefit from treatment. The first patient is expected to be enrolled in the first half of 2023<\/p>\n<\/li>\n<\/ul>\n<p><b>About Exscientia<br \/>\n<br \/><\/b>Exscientia is an AI-driven precision medicine company committed to discovering, designing and developing the best possible drugs in the fastest and most effective manner. Exscientia developed the first-ever functional precision oncology platform to successfully guide treatment selection and improve patient outcomes in a prospective interventional clinical study, as well as to progress AI-designed small molecules into the clinical setting. Our internal pipeline is focused on leveraging our precision medicine platform in oncology, while our partnered pipeline broadens our approach to other therapeutic areas. By pioneering a new approach to medicine creation, we believe the best ideas of science can rapidly become the best medicines for patients.<\/p>\n<p>\nVisit us at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.exscientia.ai%2F&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.exscientia.ai&amp;index=5&amp;md5=4881fe6d79bc7183b28449b9a5541b92\">https:\/\/www.exscientia.ai<\/a> or follow us on Twitter <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2Fexscientiaai&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=%40exscientiaAI&amp;index=6&amp;md5=46cf82712d81d0e914f401753afba86a\">@exscientiaAI<\/a>.<\/p>\n<p><b>Exscientia Forward-Looking Statements<br \/>\n<br \/><\/b>This press release contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995, including with respect to Exscientia\u2019s plans to present at AACR, the progress of discovery and development of candidate molecules, and the timing and progress of, and data reported from, preclinical studies and clinical trials of Exscientia\u2019s product candidates, including with respect to the dosing of the first patient in the Phase 1\/2 IGNITE trial. Any statement describing Exscientia\u2019s goals, plans, expectations, financial or other projections, intentions or beliefs is a forward-looking statement and should be considered an at-risk statement. Such statements are subject to a number of risks, uncertainties and assumptions, including those related to: initiation, scope and progress of Exscientia\u2019s and its partners\u2019 planned and ongoing preclinical studies and clinical trials and ramifications for the cost thereof; clinical, scientific, regulatory and technical developments; the process of discovering, developing and commercialising product candidates that are safe and effective for use as human therapeutics; and other factors. In light of these risks and uncertainties, and other risks and uncertainties that are described in the Risk Factors section and other sections of Exscientia\u2019s Annual Report on Form 20-F, filed with the Securities and Exchange Commission (SEC) on March 23, 2022 (File No. 001-40850), and other filings that Exscientia makes with the SEC from time to time (which are available at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.sec.gov%2F&amp;esheet=53383647&amp;newsitemid=20230419005391&amp;lan=en-US&amp;anchor=https%3A%2F%2Fwww.sec.gov%2F&amp;index=7&amp;md5=81ae9c18c4a64990686882c21178b251\">https:\/\/www.sec.gov\/<\/a>), the events and circumstances discussed in such forward-looking statements may not occur, and Exscientia\u2019s actual results could differ materially and adversely from those anticipated or implied thereby. Although Exscientia\u2019s forward-looking statements reflect the good faith judgement of its management, these statements are based only on facts and factors currently known by the Company at the time of this press release. As a result, you are cautioned not to rely on these forward-looking statements.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20230419005391\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20230419005391\/en\/<\/a><\/span><\/p>\n<p><b>Investor Relations:<br \/>\n<\/b><br \/>Sara Sherman<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:investors@exscientia.ai\">investors@exscientia.ai<\/a><\/p>\n<p><b>Media:<br \/>\n<\/b><br \/>Oliver Stohlmann<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:media@exscientia.ai\">media@exscientia.ai<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Florida Europe United States United Kingdom North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Technology Research Clinical Trials Health Technology Biotechnology Health Science Artificial Intelligence Oncology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230419005391\/en\/1767906\/3\/Exscientia_Logo_for_BW.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development &#8211; Includes recent advancements from precision designed compounds &#8211; &#8211; Functional personalised medicine platform unveiling unique adenosine biomarker to enrich for patients more likely to respond to treatment &#8211; OXFORD, England&#8211;(BUSINESS WIRE)&#8211; Exscientia plc (Nasdaq: EXAI) today announced four presentations at the American Association for Cancer Research (AACR) Annual Meeting 2023, being held from April 14-19, 2023 in Orlando, FL. \u201cWe\u2019re excited to further validate Exscientia\u2019s end-to-end approach of integrating outstanding science with cutting-edge AI-driven precision medicine and translational research capabilities,\u201d said Andrew Hopkins, D.Phil, founder and Chief Executive Officer of Exscientia. \u201cThe clinical and preclinical data showcased at AACR demonstrate how our approaches help not only efficiently design &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-749101","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development &#8211; Includes recent advancements from precision designed compounds &#8211; &#8211; Functional personalised medicine platform unveiling unique adenosine biomarker to enrich for patients more likely to respond to treatment &#8211; OXFORD, England&#8211;(BUSINESS WIRE)&#8211; Exscientia plc (Nasdaq: EXAI) today announced four presentations at the American Association for Cancer Research (AACR) Annual Meeting 2023, being held from April 14-19, 2023 in Orlando, FL. \u201cWe\u2019re excited to further validate Exscientia\u2019s end-to-end approach of integrating outstanding science with cutting-edge AI-driven precision medicine and translational research capabilities,\u201d said Andrew Hopkins, D.Phil, founder and Chief Executive Officer of Exscientia. \u201cThe clinical and preclinical data showcased at AACR demonstrate how our approaches help not only efficiently design &hellip; Continue reading &quot;Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-19T13:21:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"7 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development\",\"datePublished\":\"2023-04-19T13:21:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/\"},\"wordCount\":1382,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/\",\"name\":\"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"datePublished\":\"2023-04-19T13:21:54+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#primaryimage\",\"url\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"contentUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\",\"name\":\"Market Newsdesk\",\"description\":\"Latest Business News in Real Time\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\",\"name\":\"Newsdesk\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"caption\":\"Newsdesk\"},\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/author\\\/newsdesk\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/","og_locale":"en_US","og_type":"article","og_title":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk","og_description":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development &#8211; Includes recent advancements from precision designed compounds &#8211; &#8211; Functional personalised medicine platform unveiling unique adenosine biomarker to enrich for patients more likely to respond to treatment &#8211; OXFORD, England&#8211;(BUSINESS WIRE)&#8211; Exscientia plc (Nasdaq: EXAI) today announced four presentations at the American Association for Cancer Research (AACR) Annual Meeting 2023, being held from April 14-19, 2023 in Orlando, FL. \u201cWe\u2019re excited to further validate Exscientia\u2019s end-to-end approach of integrating outstanding science with cutting-edge AI-driven precision medicine and translational research capabilities,\u201d said Andrew Hopkins, D.Phil, founder and Chief Executive Officer of Exscientia. \u201cThe clinical and preclinical data showcased at AACR demonstrate how our approaches help not only efficiently design &hellip; Continue reading \"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/","og_site_name":"Market Newsdesk","article_published_time":"2023-04-19T13:21:54+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"7 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development","datePublished":"2023-04-19T13:21:54+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/"},"wordCount":1382,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/","name":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development - Market Newsdesk","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#primaryimage"},"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","datePublished":"2023-04-19T13:21:54+00:00","author":{"@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"breadcrumb":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#primaryimage","url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","contentUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230419005391r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en"},{"@type":"BreadcrumbList","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/data-presented-at-aacr-2023-highlights-exscientias-clinical-and-preclinical-development\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.marketnewsdesk.com\/"},{"@type":"ListItem","position":2,"name":"Data Presented at AACR 2023 Highlights Exscientia\u2019s Clinical and Preclinical Development"}]},{"@type":"WebSite","@id":"https:\/\/www.marketnewsdesk.com\/#website","url":"https:\/\/www.marketnewsdesk.com\/","name":"Market Newsdesk","description":"Latest Business News in Real Time","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.marketnewsdesk.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979","name":"Newsdesk","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","caption":"Newsdesk"},"url":"https:\/\/www.marketnewsdesk.com\/index.php\/author\/newsdesk\/"}]}},"_links":{"self":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/749101","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/comments?post=749101"}],"version-history":[{"count":0,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/749101\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/media?parent=749101"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/categories?post=749101"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/tags?post=749101"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}