{"id":747749,"date":"2023-04-14T08:05:20","date_gmt":"2023-04-14T12:05:20","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/"},"modified":"2023-04-14T08:05:20","modified_gmt":"2023-04-14T12:05:20","slug":"natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/","title":{"rendered":"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdisc { list-style-type: disc }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting<\/b><\/p>\n<p class=\"bwalignc\"><i>Includes long-term follow-up data (&gt;5 years) in patients with muscle-invasive bladder cancer and additional studies in colorectal, gastroesophageal and hepatocellular carcinoma<\/i><\/p>\n<p>AUSTIN, Texas&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.natera.com%2F&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=Natera%2C+Inc.&amp;index=1&amp;md5=901336cf272f0631c00b0d47e0816e61\">Natera, Inc.<\/a> (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced new data on its Signatera molecular residual disease (MRD) test being presented at the annual meeting of the American Association for Cancer Research (AACR) taking place April 14 \u2013 19, 2023.<\/p>\n<p>\nNatera and its collaborators will present findings from five studies on Signatera in esophago-gastric adenocarcinoma, muscle-invasive bladder cancer (MIBC), colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Highlights include:<\/p>\n<ul class=\"bwlistdisc\">\n<li>\nctDNA prediction of tumor response and recurrence in patients with esophago-gastric carcinoma receiving FLOT + immunotherapy (avelumab) pre- and post-surgery<\/p>\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\nctDNA prediction of tumor response and recurrence in patients with MIBC, with and without neoadjuvant therapy, with long term follow-up (median 68 months) after radical cystectomy<\/p>\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\nGenomic profiling of &gt;13,000 patients with early (\u226450 years old) vs late (\u226560 years old) onset CRC<\/p>\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\nPotential of ctDNA to guide imaging-based surveillance strategies in patients after surgery for peritoneal metastases from CRC<\/p>\n<\/li>\n<\/ul>\n<ul class=\"bwlistdisc\">\n<li>\nctDNA as a pharmacodynamic and predictive biomarker in patients with resectable HCC treated with immunotherapy (cemiplimab) pre- and post-surgery<\/p>\n<\/li>\n<\/ul>\n<p>\n\u201cWe are pleased to share additional Signatera data at this year\u2019s AACR annual meeting that continues to highlight the important role of personalized MRD testing in assessing treatment response and predicting relapse across a broad range of indications,\u201d said Minetta Liu, M.D., chief medical officer of oncology at Natera. \u201cThese data presentations underscore Natera\u2019s commitment to generating novel insights on MRD testing and genomic testing to help advance cancer care.\u201d<\/p>\n<p>\nThe full list of Signatera poster presentations at AACR is below.<\/p>\n<p><b>Abstract #2178 | April 17, 9:00 AM &#8211; 12:30 PM<br \/>\n<br \/><\/b>Presenter: Thomas U. Marron, M.D., Ph.D. &#8211; Icahn School of Medicine at Mount Sinai<br \/>\n<br \/><i>Circulating tumor DNA (ctDNA) correlates closely with tumor necrosis and relapse-free survival (RFS) in hepatocellular carcinoma (HCC) patients treated with perioperative cemiplimab<\/i><\/p>\n<p><b>Abstract #5600 | April 18, 1:30 &#8211; 5:00 PM<br \/>\n<br \/><\/b>Presenter: Sia Viborg Lindskrog &#8211; Aarhus University Hospital<br \/>\n<br \/><i>Utility of circulating tumor DNA and transcriptomic profiling in predicting outcome in muscle invasive bladder cancer patients<\/i><\/p>\n<p><b>Abstract #5591 | April 18, 1:30 &#8211; 5:00 PM<br \/>\n<br \/><\/b>Presenter: Marco Gerlinger, M.D., FRCP &#8211; Barts Cancer Institute &amp; St Bartholomew&#8217;s Hospital<br \/>\n<br \/><i>Circulating tumor DNA for recurrence prediction and efficacy analysis in the ICONIC trial of peri-operative FLOT and avelumab (PD-L1) in localized esophago-gastric adenocarcinoma<\/i><\/p>\n<p><b>Abstract #5604 | April 18, 1:30 &#8211; 5:00 PM<br \/>\n<br \/><\/b>Presenter: Kevin Chang, M.S. &#8211; University of Iowa<br \/>\n<br \/><i>Circulating tumor DNA for predicting peritoneal only disease recurrence in colon cancer<\/i><\/p>\n<p><b>Abstract #6696 | April 19, 9:00 AM &#8211; 12:30 PM<br \/>\n<br \/><\/b>Presenter: Eric Lander, M.D. &#8211; Vanderbilt University Medical Center<br \/>\n<br \/><i>Genomic alterations associated with early-onset and late-onset colorectal cancer<\/i><\/p>\n<p>\nThe AACR abstracts are available <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.abstractsonline.com%2Fpp8%2F%23%21%2F10828%2F&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=here&amp;index=2&amp;md5=ddca9594fc15a2fcc3140f8c1589c2df\">here<\/a>.<\/p>\n<p><b>About Signatera<\/b><\/p>\n<p><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3732835-1%26h%3D1685092079%26u%3Dhttps%253A%252F%252Fwww.natera.com%252Foncology%252Fsignatera-advanced-cancer-detection%252F%26a%3DSignatera&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=Signatera&amp;index=3&amp;md5=8e1f54eff556e5cb9ec521bb86728f30\">Signatera<\/a> is a custom-built circulating tumor DNA (ctDNA) test for treatment monitoring and molecular residual disease (MRD) assessment in patients previously diagnosed with cancer. The test is available for both clinical and research use, and has been granted three Breakthrough Device Designations by the FDA for multiple cancer types and indications. The Signatera test is personalized and tumor-informed, providing each individual with a customized blood test tailored to fit the unique signature of clonal mutations found in that individual\u2019s tumor. Signatera is intended to detect and quantify cancer left in the body, at levels down to a single tumor molecule in a tube of blood, to identify recurrence earlier and to help optimize treatment decisions.<\/p>\n<p><b>About Natera<\/b><\/p>\n<p>\nNatera\u2122 is a global leader in cell-free DNA testing, dedicated to oncology, women\u2019s health, and organ health. We aim to make personalized genetic testing and diagnostics part of the standard of care to protect health, and inform earlier, more targeted interventions that help lead to longer, healthier lives. Natera\u2019s tests are validated by more than 100 peer-reviewed publications that demonstrate high accuracy. Natera operates ISO 13485-certified and CAP-accredited laboratories certified under the Clinical Laboratory Improvement Amendments (CLIA) in Austin, Texas and San Carlos, California. For more information, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3732835-1%26h%3D4126071259%26u%3Dhttp%253A%252F%252Fwww.natera.com%252F%26a%3Dwww.natera.com&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=www.natera.com&amp;index=4&amp;md5=eeb15cd536c9b85f6a0533a922243295\">www.natera.com<\/a>.<\/p>\n<p><b>Forward-Looking Statements<\/b><\/p>\n<p>\nAll statements other than statements of historical facts contained in this press release are forward-looking statements and are not a representation that Natera\u2019s plans, estimates, or expectations will be achieved. These forward-looking statements represent Natera\u2019s expectations as of the date of this press release, and Natera disclaims any obligation to update the forward-looking statements. These forward-looking statements are subject to known and unknown risks and uncertainties that may cause actual results to differ materially, including with respect to whether the results of clinical or other studies will support the use of our product offerings, the impact of results of such studies, our expectations of the reliability, accuracy and performance of our tests, or of the benefits of our tests and product offerings to patients, providers and payers. Additional risks and uncertainties are discussed in greater detail in &#8220;Risk Factors&#8221; in Natera\u2019s recent filings on Forms 10-K and 10-Q and in other filings Natera makes with the SEC from time to time. These documents are available at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3732835-1%26h%3D753994123%26u%3Dhttp%253A%252F%252Fwww.natera.com%252Finvestors%26a%3Dwww.natera.com%252Finvestors&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=www.natera.com%2Finvestors&amp;index=5&amp;md5=61d0f8ed24a6a00156fc680bdca9559e\">www.natera.com\/investors<\/a> and <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3732835-1%26h%3D3019794395%26u%3Dhttp%253A%252F%252Fwww.sec.gov%252F%26a%3Dwww.sec.gov&amp;esheet=53381133&amp;newsitemid=20230414005088&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=6&amp;md5=d311dc1839c4ef07e26f8e1ebb1ca072\">www.sec.gov<\/a>.<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230414005088r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20230414005088\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20230414005088\/en\/<\/a><\/span><\/p>\n<p>\nInvestor Relations: Mike Brophy, CFO, Natera, Inc., 510-826-2350, <a rel=\"nofollow\" href=\"mailto:investor@natera.com\">investor@natera.com<br \/>\n<\/a><br \/>Media: Lesley Bogdanow, VP of Corporate Communications, Natera, Inc., <a rel=\"nofollow\" href=\"mailto:pr@natera.com\">pr@natera.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> Texas United States North America<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Pharmaceutical Oncology Health Medical Devices Genetics Clinical Trials Other Health<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20230414005088\/en\/1736351\/3\/Natera_floret_Logo_%281%29.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting Includes long-term follow-up data (&gt;5 years) in patients with muscle-invasive bladder cancer and additional studies in colorectal, gastroesophageal and hepatocellular carcinoma AUSTIN, Texas&#8211;(BUSINESS WIRE)&#8211;Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced new data on its Signatera molecular residual disease (MRD) test being presented at the annual meeting of the American Association for Cancer Research (AACR) taking place April 14 \u2013 19, 2023. Natera and its collaborators will present findings from five studies on Signatera in esophago-gastric adenocarcinoma, muscle-invasive bladder cancer (MIBC), colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Highlights include: ctDNA prediction of tumor response and recurrence in patients with esophago-gastric carcinoma receiving FLOT &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-747749","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting Includes long-term follow-up data (&gt;5 years) in patients with muscle-invasive bladder cancer and additional studies in colorectal, gastroesophageal and hepatocellular carcinoma AUSTIN, Texas&#8211;(BUSINESS WIRE)&#8211;Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced new data on its Signatera molecular residual disease (MRD) test being presented at the annual meeting of the American Association for Cancer Research (AACR) taking place April 14 \u2013 19, 2023. Natera and its collaborators will present findings from five studies on Signatera in esophago-gastric adenocarcinoma, muscle-invasive bladder cancer (MIBC), colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Highlights include: ctDNA prediction of tumor response and recurrence in patients with esophago-gastric carcinoma receiving FLOT &hellip; Continue reading &quot;Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-04-14T12:05:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230414005088r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting\",\"datePublished\":\"2023-04-14T12:05:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/\"},\"wordCount\":909,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20230414005088r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\\\/\",\"name\":\"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/","og_locale":"en_US","og_type":"article","og_title":"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting - Market Newsdesk","og_description":"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting Includes long-term follow-up data (&gt;5 years) in patients with muscle-invasive bladder cancer and additional studies in colorectal, gastroesophageal and hepatocellular carcinoma AUSTIN, Texas&#8211;(BUSINESS WIRE)&#8211;Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced new data on its Signatera molecular residual disease (MRD) test being presented at the annual meeting of the American Association for Cancer Research (AACR) taking place April 14 \u2013 19, 2023. Natera and its collaborators will present findings from five studies on Signatera in esophago-gastric adenocarcinoma, muscle-invasive bladder cancer (MIBC), colorectal cancer (CRC) and hepatocellular carcinoma (HCC). Highlights include: ctDNA prediction of tumor response and recurrence in patients with esophago-gastric carcinoma receiving FLOT &hellip; Continue reading \"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/","og_site_name":"Market Newsdesk","article_published_time":"2023-04-14T12:05:20+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230414005088r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting","datePublished":"2023-04-14T12:05:20+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/"},"wordCount":909,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20230414005088r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/natera-announces-new-signatera-mrd-data-at-2023-aacr-annual-meeting\/","name":"Natera Announces New Signatera\u2122 MRD Data at 2023 AACR Annual Meeting - 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