{"id":741177,"date":"2023-03-20T08:22:48","date_gmt":"2023-03-20T12:22:48","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/"},"modified":"2023-03-20T08:22:48","modified_gmt":"2023-03-20T12:22:48","slug":"tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/","title":{"rendered":"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"justify\">NEW YORK, March  20, 2023  (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences Ltd. (Nasdaq: TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company enabling breakthrough immunotherapies via novel routes of drug delivery, today announces that it has been notified that Gabriele Cerrone, its Chairman and Acting Chief Executive Officer, purchased 45,000 common shares at $0.66 per share, bringing his total holding to 38,685,737 common shares.<\/p>\n<p align=\"justify\">\n        <strong>About Foralumab<\/strong><br \/>\n        <br \/>Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor, dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets, an effect demonstrated in patients with COVID and with multiple sclerosis, as well as in healthy normal subjects. Intranasal foralumab Phase 2 trials are expected to start in Q3 2023 in patients with non-active SPMS. Immunomodulation by nasal anti-CD3 mAb represents a novel avenue for treatment of inflammatory human diseases.<sup>1<\/sup><\/p>\n<p align=\"justify\">\n        <strong>About\u00a0Tiziana Life Sciences<\/strong><br \/>\n        <br \/>Tiziana Life Sciences\u00a0is a clinical-stage biopharmaceutical company developing breakthrough therapies using transformational drug delivery technologies to enable alternative routes of immunotherapy. Tiziana\u2019s innovative nasal, oral and inhalation approaches in development have the potential to provide an improvement in efficacy as well as safety and tolerability compared to intravenous (IV) delivery. Tiziana\u2019s lead candidate, intranasal foralumab, the only fully human anti-CD3 mAb, has demonstrated a favorable safety profile and clinical response in patients in studies to date. Tiziana\u2019s technology for alternative routes of immunotherapy has been patented with several applications pending and is expected to allow for broad pipeline applications.<\/p>\n<p align=\"justify\">For further inquiries:<\/p>\n<p>\n        <strong>Tiziana Life Sciences Ltd<\/strong><br \/>\n        <br \/>Paul Spencer, Business Development and Investor Relations<br \/>+44 (0) 207 495 2379<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=yZWvlEx-nfodAdkyqZ_0SnfNh9XxZWpN_rl_tP5FWjZ14dz9ifbOTCN2adlKukTC8TPis-bg50wQ9NKH05nwELxv5OpOLgeyUGO_aFGwCpGmTy2m167qMtil4A137CMspPDxiBQyiMZvtu5hAz6wytDfeIYfuawpkNT9n4qeQN90QLuOIYMiP1i7aRxkEjR-_1ZaFtP9U5-4X50WApq6ITvXGjKozo-46-9yEpLjL4mlFN5pDv8XyNczud4trts_PTBYfvsA3Kv50yPWp4w0C95SWacl-mc1PGUPvgj2MWg=\" rel=\"nofollow noopener\" target=\"_blank\">info@tizianalifesciences.com<\/a><\/p>\n<p>\n        <strong>Investors:<\/strong><br \/>\n        <br \/>Irina Koffler<br \/>LifeSci Advisors, LLC<br \/>646.970.4681<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=3jRT097pvFj_1UzQVE8it1bUCcI-p43lM2Vu3VsO5HegL0vrN2tGNP8Yf4UJJKZgdLSjsJtD8_1umk40WS4h0PnEueDwPFo36-lVtv2DHjLw0RS2oZmY2o8XJHQiQ-NpfPGSk-gFnvmFzN0qPeWSHNlvPJI0hf2rrCXU9QVaWTltETe0fPN9dSmkfUnvej9HwAanjb7UwDakxDAjLxlDz4XsGetV48oIp7bhGbcJp2ZYasyX0Ra-xDW7wamicPa6QHeYBwL15H7Si7nAGEqj4N0DQIOCbfIBCBtLY_d4vs3pzrq3DcBp7oHTCo1WKCXW5lS9F5JU31QtssIOaR7L6Cv35YmR-xaHPOfQJ6QpTdcko99dXEUwtw-HeAIBW6BOECiBHn7jT56nRSMfV69BKaq_VRIzCVhvbg5gzzuNLLDrMHkDK0zqUiZH1yplG-Tw60BgQG8fHzXqBs33Nvk5sihwk0R4o_aefIFAyje4_oh8fhuQckEiH5x-ByieFvCxfbBOUxvZdPejrehlWHZbf_Ka3HnNVYVOwyZ8Yb-8f6uGQXJ8VUzHcXstAqc7ON4saV61OiTULRC_WPHPAX-9zmSqe1RQrA2D0JzhUsYrVSuAHi1R5c7Bf9Wz6x7YVpnrHyJ8S2OcbEv0Lf-7mp6tbPupUtIgak5Rc3oKnK_QwC9FulVLmMYSf8FolimS8A1YHz48XZQqVecbDiG1ZXV5_tyyA_oBHBHLN9yLnkqIvALOzzs7o58CIB2ol7a5-0nLY1YcyGZz3-RYtghn3jqqK_-MgriF60xSJg0fVy8zhwih3NnZJa5zB-Yw6OzZ2ycJiBsyMle-T-ubprxmZ9eEag==\" rel=\"nofollow noopener\" target=\"_blank\">ikoffler@lifesciadvisors.com<\/a>\u00a0<\/p>\n<p>______________________________<\/p>\n<p>\n        <sup>1<\/sup><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=l9Dv8EMbrftmWrnZe9km9vA4eaXJ5-OvXwRcRs2-dysCMjgWg6EFlLoaJfyb2G62r0mBhzuyKhzBzW2s4mCWS96PLago8MiNU5r1uJZnRcmZPSZsEm0xlyIjxMygt-cKiAo_69Wylfw024LKvTaws20ErTaPXjGfe2l--ToZ_zg=\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2220272120<\/a>\n      <\/p>\n<p>\u00a0<\/p>\n<p>      <img decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc5MTM4NiM1NDcwNTEzIzIxMjM4ODU=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" src=\"https:\/\/ml.globenewswire.com\/media\/Zjk2MWIyMmYtYjNhNy00YWM4LWEwMGUtMTE0MWFmMWE2ZDllLTExMzU0NTY=\/tiny\/Tiziana-Life-Sciences-Plc.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>NEW YORK, March 20, 2023 (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences Ltd. (Nasdaq: TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company enabling breakthrough immunotherapies via novel routes of drug delivery, today announces that it has been notified that Gabriele Cerrone, its Chairman and Acting Chief Executive Officer, purchased 45,000 common shares at $0.66 per share, bringing his total holding to 38,685,737 common shares. About Foralumab Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor, dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets, an effect demonstrated in patients with COVID and with multiple sclerosis, as well &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-741177","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"NEW YORK, March 20, 2023 (GLOBE NEWSWIRE) &#8212; Tiziana Life Sciences Ltd. (Nasdaq: TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company enabling breakthrough immunotherapies via novel routes of drug delivery, today announces that it has been notified that Gabriele Cerrone, its Chairman and Acting Chief Executive Officer, purchased 45,000 common shares at $0.66 per share, bringing his total holding to 38,685,737 common shares. About Foralumab Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor, dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets, an effect demonstrated in patients with COVID and with multiple sclerosis, as well &hellip; Continue reading &quot;Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-20T12:22:48+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc5MTM4NiM1NDcwNTEzIzIxMjM4ODU=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO\",\"datePublished\":\"2023-03-20T12:22:48+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/\"},\"wordCount\":301,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODc5MTM4NiM1NDcwNTEzIzIxMjM4ODU=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\\\/\",\"name\":\"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO - 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(Nasdaq: TLSA) (\u201cTiziana\u201d or the \u201cCompany\u201d), a biotechnology company enabling breakthrough immunotherapies via novel routes of drug delivery, today announces that it has been notified that Gabriele Cerrone, its Chairman and Acting Chief Executive Officer, purchased 45,000 common shares at $0.66 per share, bringing his total holding to 38,685,737 common shares. About Foralumab Activated T cells play an important role in the inflammatory process. Foralumab, the only fully human anti-CD3 monoclonal antibody (mAb), binds to the T cell receptor, dampens inflammation by modulating T cell function, thereby suppressing effector features in multiple immune cell subsets, an effect demonstrated in patients with COVID and with multiple sclerosis, as well &hellip; Continue reading \"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/","og_site_name":"Market Newsdesk","article_published_time":"2023-03-20T12:22:48+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc5MTM4NiM1NDcwNTEzIzIxMjM4ODU=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO","datePublished":"2023-03-20T12:22:48+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/"},"wordCount":301,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc5MTM4NiM1NDcwNTEzIzIxMjM4ODU=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/tiziana-life-sciences-announces-purchase-of-common-shares-by-chairman-and-acting-ceo-2\/","name":"Tiziana Life Sciences Announces Purchase of Common Shares by Chairman and Acting CEO - 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