{"id":740172,"date":"2023-03-15T07:04:41","date_gmt":"2023-03-15T11:04:41","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/"},"modified":"2023-03-15T07:04:41","modified_gmt":"2023-03-15T11:04:41","slug":"hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/","title":{"rendered":"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook"},"content":{"rendered":"<div class=\"mw_release\">\n<ul>\n<li style=\"text-align:left\">Data from Phase\u00a02 study of HB-200 in combination with pembrolizumab in head and neck cancers expected in 2Q 2023<\/li>\n<\/ul>\n<ul>\n<li style=\"text-align:justify\">Phase\u00a01 HB-300 trial in metastatic castration-resistant prostate cancer open for enrollment<\/li>\n<\/ul>\n<ul>\n<li style=\"text-align:justify\">KRAS program (HB-700) achieved its first milestone payment in the Roche collaboration in February 2023; plan to submit IND in 1H 2024<\/li>\n<\/ul>\n<ul>\n<li style=\"text-align:justify\">Strengthened cash position of $113.4\u00a0million at year-end; additional $15.0\u00a0million cash inflow from collaboration milestones in early 2023<\/li>\n<\/ul>\n<p align=\"justify\">NEW YORK and VIENNA, March  15, 2023  (GLOBE NEWSWIRE) &#8212; HOOKIPA Pharma Inc. (NASDAQ: HOOK, \u2018HOOKIPA\u2019), a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform, today reported financial results and provided a corporate update for the fourth quarter and full year 2022, as well as the outlook for 2023.<\/p>\n<p align=\"justify\">\n        <em>\u201cWe made substantial progress in 2022 as we work to develop our novel arenaviral immunotherapies against a variety of cancers and infectious diseases. Our lead candidate, HB-200, advanced to Phase 2 in combination with pembrolizumab for head and neck cancers; our HB-300 program in prostate cancer advanced toward the clinic with IND acceptance; and we added a strategic collaboration with Roche to develop our HB-700 program for KRAS-mutated cancers,&#8221; <\/em>said Joern Aldag, Chief Executive Officer at HOOKIPA. <em>\u201cWe have started the year strongly with our HB-300 program now open for enrollment, and our HB-700 program achieving a key milestone as we move toward the clinic. We remain focused on driving our rich pipeline forward and generating clinical data that expands the evidence of our arenaviral platform technology to help address unmet needs in cancer.&#8221; <\/em><\/p>\n<p align=\"justify\">\n        <strong>Oncology Portfolio<\/strong><br \/>\n        <br \/>With a focus on its oncology portfolio, HOOKIPA advanced programs in each of the three pillars of its oncology strategy: targeting oncoviral antigens (HB-200); targeting self-antigens (HB-300); and targeting shared neoantigens (HB-700).<\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>HB-200, a novel immunotherapy to treat head and neck cancers, advanced to Phase 2 in combination with pembrolizumab in 1<\/strong><br \/>\n          <sup><br \/>\n            <strong>st<\/strong><br \/>\n          <\/sup><br \/>\n          <strong>&#8211; and 2<\/strong><br \/>\n          <sup><br \/>\n            <strong>nd<\/strong><br \/>\n          <\/sup><br \/>\n          <strong>+-line settings and alone as post-standard of care treatment. Enrollment is on track,<\/strong><br \/>\n          <strong> and HOOKIPA will provide a data update in 2Q 2023 via press release and an investor call. <\/strong><\/p>\n<ul type=\"circle\">\n<li style=\"text-align:justify\">In January 2022, the <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-first-patient-enrolled-phase-2-trial\" rel=\"nofollow noopener\" target=\"_blank\">first patient was dosed<\/a> in the Phase 2 trial evaluating HB-200 in combination with pembrolizumab, as a potential treatment of 1<sup>st<\/sup>&#8211; and 2<sup>nd<\/sup>+-line advanced metastatic Human Papillomavirus 16 Positive (HPV16-positive) squamous cell head and neck cancers (HNSCC).<\/li>\n<li style=\"text-align:justify\">In June 2022, HOOKIPA announced positive Phase 1 <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-positive-phase-1-data-and-phase-2-plans-hb-200\" rel=\"nofollow noopener\" target=\"_blank\">monotherapy<\/a> data for HB-200 for the treatment of advanced head and neck cancers at the American Society of Clinical Oncology (ASCO) Annual Meeting. Alternating 2-vector therapy showed superior antigen-specific T cell responses, more robust anti-tumor activity and similar tolerability vs. single-vector therapy.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Novel prostate cancer immunotherapy, HB-300, achieved a regulatory milestone with Investigational New Drug Application (IND) acceptance.<\/strong> In July 2022, HOOKIPA announced that the <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/fda-accepts-hookipas-investigational-new-drug-application-hb-300\" rel=\"nofollow noopener\" target=\"_blank\">U.S. Food and Drug Administration (FDA) accepted<\/a> HOOKIPA\u2019s IND for HB-300 for the treatment of metastatic castration-resistant prostate cancer.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>HOOKIPA further expanded pipeline and strategic collaborations with the Roche\/HB-700 agreement for KRAS-mutated cancers. <\/strong>In October 2022, HOOKIPA announced a <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-strategic-collaboration-and-license-agreement\" rel=\"nofollow noopener\" target=\"_blank\">strategic collaboration and license agreement<\/a> to develop HB-700 for KRAS-mutated cancers and a second undisclosed novel immunotherapy candidate. The Roche collaboration represents the first oncology license agreement for HOOKIPA. Under the terms of the agreement, HOOKIPA received $25 million in upfront cash, with an additional $15 million payment if Roche exercises the option to add an additional product candidate, and potential future milestone payments up to approximately $930 million for both programs, plus tiered royalties. In February 2023, HOOKIPA achieved a <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-achieves-10-million-milestone-payment-development\" rel=\"nofollow noopener\" target=\"_blank\">$10 million non-dilutive milestone payment<\/a>, which reflected the start of the HB-700 manufacturing process to support a Phase 1 clinical trial.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Drug Master File (DMF) accepted to support future regulatory submissions in the US <\/strong>in July 2022<strong>. <\/strong>The information contained in the DMF may be used to support additional INDs and other submissions. The DMF acceptance is HOOKIPA\u2019s biggest step to date toward a \u201cplug &amp; play\u201d platform. The DMF shortens the future time interval between preclinical work and IND submission as HOOKIPA can forgo resubmission of the arenavirus backbone data with each new IND submission.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Potential of arenaviral immunotherapies in novel combinations and against tumor self-antigens highlighted at AACR. <\/strong>In April 2022, HOOKIPA presented positive data at the <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/new-data-show-hookipas-arenaviral-immunotherapies-induce-potent\" rel=\"nofollow noopener\" target=\"_blank\">2022 American Association for Cancer Research Annual Meeting<\/a> showing HOOKIPA\u2019s arenaviral immunotherapies induced potent T cell responses in novel combinations (such as co-stimulatory 4-1BB agonists or adoptive cell transfer) and against tumor self-antigens. The results highlighted the potential of HOOKIPA\u2019s novel arenaviral platform as a backbone of potential combination therapies, as well as expanded evidence reinforcing the scientific approach for the HB-300 program in prostate cancer. Of note, compelling pre-clinical data on the novel combination of arenaviral immunotherapy and PD-1 targeted IL-2 variant against a tumor self-antigen will be presented as an oral presentation at the 2023 AACR meeting in April.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Infectious Disease Portfolio<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Collaboration with Gilead Sciences continues to advance development of functional cures for Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV).<\/strong><\/p>\n<ul type=\"circle\">\n<li style=\"text-align:justify\">In February 2022, HOOKIPA and Gilead announced an <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-and-gilead-amend-collaboration-and-license-agreement\" rel=\"nofollow noopener\" target=\"_blank\">amended collaboration<\/a> and license agreement to develop HB-500, a novel arenaviral immunotherapy as a component of a potential functional curative regimen for HIV. HOOKIPA assumed development responsibility for advancing the HIV program through the completion of a Phase 1b clinical trial. Financial terms included a $4 million preclinical milestone, a $15 million non-refundable initiation fee, a $5 million equity investment at a premium to the then-current market price, and up to an additional $30 million of equity financing that can be drawn at HOOKIPA\u2019s discretion by December 31, 2023.<\/li>\n<li style=\"text-align:justify\">HOOKIPA\u2019s HB-400 program, in collaboration with Gilead as a curative regimen for HBV, advanced towards the clinic with the submission of the clinical trial application (IND equivalent) and HOOKIPA\u2019s completion of the regulatory support package for Gilead\u2019s Phase 1 clinical trial. This milestone earned HOOKIPA a <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-achieves-5-million-milestone-payment-gilead\" rel=\"nofollow noopener\" target=\"_blank\">$5 million non-dilutive payment<\/a> under its collaboration agreement in January 2023. Gilead is solely responsible for further development and commercialization of the HBV product candidate; the first participant in the Phase 1 clinical trial is expected to be dosed in 2023.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">\n          <strong>Final Phase 2 data on HB-101 for Cytomegalovirus (CMV) prevention in live donor kidney transplant recipients:<\/strong> Results of the Phase 2 clinical trial (NCT03629080), a prophylactic CMV vaccine candidate, show that HB-101 was immunogenic after at least two doses, inducing similar antibody responses to those observed in Phase 1. All participants who received three doses of HB-101, and for whom immunogenicity data were available, demonstrated a CMV-specific T cell immune response. In the efficacy analysis, participants who received three doses of HB-101 had a lower incidence of CMV viremia compared to the matched placebo group. Two doses of HB-101 did not reduce incidence of CMV infection, CMV disease, or use of antiviral treatment post-transplant compared to the placebo group. HOOKIPA has decided not to further invest in the HB-101 program, based on its corporate strategy to focus on oncology.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Corporate Updates<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">In March 2022, HOOKIPA completed a <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-announces-pricing-750-million-public-offering\" rel=\"nofollow noopener\" target=\"_blank\">$75 million public offering<\/a> of common stock and non-voting convertible preferred stock.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">The company added two new Board members: <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-appoints-tim-reilly-phd-its-board-directors\" rel=\"nofollow noopener\" target=\"_blank\">Tim Reilly, Ph.D.<\/a>, in April, and <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-appoints-katia-schlienger-md-phd-chief-medical\" rel=\"nofollow noopener\" target=\"_blank\">Malte Peters, M.D.<\/a>, appointed in December and effective January 1, 2023. In March 2023, the Company appointed <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-appoints-terry-coelho-its-board-directors\" rel=\"nofollow noopener\" target=\"_blank\">Terry Coelho<\/a> to the board, effective, April 3, 2023.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">Over the course of 2022, HOOKIPA announced several executive leadership changes. In March 2022, Klaus Orlinger, Ph.D. was promoted to <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-promotion-klaus-orlinger-phd-chief-scientific\" rel=\"nofollow noopener\" target=\"_blank\">Chief Scientific Officer<\/a>. Christine D. Baker was promoted to <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-promotion-christine-d-baker-chief-operating\" rel=\"nofollow noopener\" target=\"_blank\">Chief Operating Officer<\/a> in May 2022. In June 2022, Roman Necina was appointed to the newly created role of <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-announces-executive-leadership-changes\" rel=\"nofollow noopener\" target=\"_blank\">Chief Development Officer<\/a>. In December 2022, Katia Schlienger, M.D., Ph.D., was promoted to <a href=\"https:\/\/ir.hookipapharma.com\/news-releases\/news-release-details\/hookipa-pharma-appoints-katia-schlienger-md-phd-chief-medical\" rel=\"nofollow noopener\" target=\"_blank\">Chief Medical Officer<\/a>, effective January 1, 2023.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Upcoming Milestones<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">Phase 2 HB-200 in HPV16+ head and neck cancers\n<ul type=\"circle\">\n<li style=\"text-align:justify\">1<sup>st<\/sup>-line initial data in combination with pembrolizumab: 2Q 2023<\/li>\n<li style=\"text-align:justify\">2<sup>nd<\/sup>+-line initial data in combination with pembrolizumab: 2Q 2023<\/li>\n<li style=\"text-align:justify\">Post-standard of care monotherapy: 2Q 2023<\/li>\n<li style=\"text-align:justify\">Randomized Phase 2 in 1<sup>st<\/sup>-line with pembrolizumab: study kick-off 2023 (Fast Track designation)<\/li>\n<\/ul>\n<\/li>\n<li style=\"text-align:justify\">HB-300 in prostate cancer: initial data expected 1H 2024<\/li>\n<li style=\"text-align:justify\">HB-700 in KRAS-mutated cancers: submit IND 2024<\/li>\n<li style=\"text-align:justify\">HB-400 in hepatitis B: first participant dosed 2023 (Gilead-led)<\/li>\n<li style=\"text-align:justify\">HB-500 in HIV: submit IND 2023<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Fourth Quarter and Full Year 2022 Financial Results <\/strong><br \/>\n        <br \/>\n        <strong>Cash Position:<\/strong> HOOKIPA\u2019s cash, cash equivalents and restricted cash as of December\u00a031,\u00a02022 was $113.4\u00a0million compared to $66.9\u00a0million as of December\u00a031,\u00a02021. The increase was primarily attributable to funds resulting from the amended and restated Gilead collaboration agreement, the strategic collaboration and licensing agreement with Roche and the follow-on financing in March\u00a02022, partly offset by cash used in operating activities.<\/p>\n<p align=\"justify\">HOOKIPA\u2019s cash position as of December\u00a031,\u00a02022 does not include a $5\u00a0million milestone payment that the Company received under the amended and restated Gilead collaboration agreement and a $10\u00a0million milestone payment that HOOKIPA received under the strategic collaboration and licensing agreement with Roche.<\/p>\n<p align=\"justify\">HOOKIPA does not hold cash deposits or securities at Silicon Valley Bank.<\/p>\n<p align=\"justify\">\n        <strong>Revenue<\/strong>: Revenue was $7.8\u00a0million for the three months ended December\u00a031,\u00a02022, and $14.2\u00a0million for the year ended December\u00a031,\u00a02022 compared to $3.9\u00a0million for the three months ended December\u00a031,\u00a02021 and $18.4\u00a0million for the year ended December\u00a031,\u00a02021. The decrease in the full year revenues was primarily due to lower cost reimbursements received under the collaboration agreement with Gilead. This decrease was partially offset by the recognition of a milestone payment for supporting Gilead to progress with a Phase\u00a01 clinical trial for the HBV program. A substantial part of the $4.0\u00a0million milestone payment and the $15.0\u00a0million initiation fee that were received for the HIV program under the restated Gilead collaboration agreement in the three months ended March\u00a031,\u00a02022, and the main part of the $25.0\u00a0million upfront payment that was received under the strategic collaboration and licensing agreement with Roche in the three months ended December 31, 2022, remained recorded as deferred revenue to be recognized in future accounting periods.<\/p>\n<p align=\"justify\">\n        <strong>Research and Development Expenses:<\/strong> HOOKIPA\u2019s research and development expenses were $17.6\u00a0million for the three months ended December\u00a031,\u00a02022, and $68.6\u00a0million for the year ended December\u00a031,\u00a02022 compared to $22.4\u00a0million for the three months ended December\u00a031,\u00a02021, and $82.9\u00a0million for the year ended December\u00a031,\u00a02021. The primary drivers of the decrease in research and development expenses by $14.3\u00a0million compared to the year ended December\u00a031,\u00a02021 were lower manufacturing expenses for our HB-200, HB-300 and Gilead partnered programs and lower clinical study expenses due to the completion of patient enrollment of the Phase\u00a02 trial for our HB-101 program, a decrease in personnel related expenses including stock based compensation, and a decrease in laboratory consumables, partially offset by an increase in professional and consulting fees and an increase in training and recruitment expenses.<\/p>\n<p align=\"justify\">\n        <strong>General and Administrative Expenses:<\/strong> General and administrative expenses amounted to $3.8\u00a0million for the three months ended December\u00a031,\u00a02022 and $18.8\u00a0million for the year ended December\u00a031,\u00a02022 compared to $3.5\u00a0million for the three months ended December\u00a031,\u00a02021, and $17.3\u00a0million for the year ended December\u00a031,\u00a02021. The increase was primarily due to an increase in professional and consulting fees and an increase in training and recruitment expenses, partially offset by a decrease in personnel-related expenses and a decrease in other expenses.<\/p>\n<p align=\"justify\">\n        <strong>Net Loss:<\/strong> HOOKIPA\u2019s net loss was $12.3\u00a0million for the three months ended December\u00a031,\u00a02022 and $64.9\u00a0million for the year ended December\u00a031,\u00a02022 compared to a net loss of $21.2\u00a0million for the three months ended December\u00a031,\u00a02021 and $75.7\u00a0million for the year ended December\u00a031,\u00a02021. This decrease was primarily due to a decrease in research and development expenses.<\/p>\n<p align=\"justify\">\n        <strong>Conference call: <\/strong>HOOKIPA will host a conference call and live webcast at 8:30 am EDT today to discuss its financial results and provide a corporate update.<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"max-width:20%;width:20%;min-width:20%\">Dial In:<\/td>\n<td style=\"max-width:80%;width:80%;min-width:80%\">+1 800-715-9871<\/td>\n<\/tr>\n<tr>\n<td>UK Dial In:<\/td>\n<td>0800 260-6466<\/td>\n<\/tr>\n<tr>\n<td>Austria Dial In:<\/td>\n<td>+43 800 070441<\/td>\n<\/tr>\n<tr>\n<td>Conference ID:<\/td>\n<td>7669853<\/td>\n<\/tr>\n<tr>\n<td>Webcast:<\/td>\n<td>\n            <a href=\"https:\/\/edge.media-server.com\/mmc\/p\/geawxvhj\" rel=\"nofollow noopener\" target=\"_blank\">Link<\/a>\n          <\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">The webcast and the presentation will be available within the Investors &amp; Media section of HOOKIPA\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=euZ3bvCNXD-9IoHUsmAsguy7Wtk0aeDxbkZVeWAK8f6hT--5s75kkf8rDq84LuUrZPEesHWugPZ9cxXvvndd-RHgJZdYzfAShv4-F-PIqG0aX9SQWZtuR4j7NL5-WGKP\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/ir.hookipapharma.com\/events<\/a>. An archived replay will be accessible for 30 days following the event.<\/p>\n<p align=\"justify\">\n        <strong>About HOOKIPA<br \/><\/strong>HOOKIPA Pharma Inc. (NASDAQ: HOOK) is a clinical-stage biopharmaceutical company focused on developing novel immunotherapies, based on its proprietary arenavirus platform, which are designed to mobilize and amplify targeted T cells and thereby fight or prevent serious disease. HOOKIPA\u2019s replicating and non-replicating technologies are engineered to induce robust and durable antigen-specific CD8+ T cell responses and pathogen-neutralizing antibodies. HOOKIPA\u2019s pipeline includes its wholly owned investigational arenaviral immunotherapies targeting Human Papillomavirus 16-positive cancers, prostate cancers, and other undisclosed oncology programs. HOOKIPA is collaborating with Roche on an arenaviral immunotherapeutic for KRAS-mutated cancers. In addition, HOOKIPA aims to develop functional cures of HBV and HIV in collaboration with Gilead.<\/p>\n<p align=\"justify\">Find out more about HOOKIPA online at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=V4rSrjORxWJaUKYbNi5YcTo9RFfteNTjJj_0yd3cwE7hRAV3p0vgGkIR-Aaxx3r92epmolNj2Vpl-0MkbdLEmAGo5coOcaggTy0I6Uao-Ds=\" rel=\"nofollow noopener\" target=\"_blank\">www.hookipapharma.com<\/a>.<\/p>\n<p align=\"justify\">\n        <strong>Forward Looking Statements<br \/><\/strong>Certain statements set forth in this press release constitute \u201cforward-looking\u201d statements within the meaning of the Private Securities Litigation Reform Act of 1995, as amended. Forward-looking statements can be identified by terms such as \u201cbelieves,\u201d \u201cexpects,\u201d \u201cplans,\u201d \u201cpotential,\u201d \u201cwould\u201d or similar expressions and the negative of those terms. Such forward-looking statements involve substantial risks and uncertainties that could cause HOOKIPA\u2019s research and clinical development programs, future results, performance or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others, the uncertainties inherent in the drug development process, including HOOKIPA\u2019s programs\u2019 early stage of development, the process of designing and conducting preclinical and clinical trials, the regulatory approval processes, the timing of regulatory filings, the challenges associated with manufacturing drug products, HOOKIPA\u2019s ability to successfully establish, protect and defend its intellectual property,<strong>\u00a0<\/strong>risks relating to business interruptions resulting from the coronavirus (COVID-19) disease outbreak or similar public health crises, the impact of COVID-19 on the enrollment of patients and timing of clinical results, and other matters that could affect the sufficiency of existing cash to fund\u00a0operations. HOOKIPA undertakes no obligation to update or revise any forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the company in general, see HOOKIPA\u2019s annual report on Form 10-K for the year ended December 31,\u00a02022, which is available on the Security and Exchange Commission\u2019s website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=7yPKIfYRgUc9ifvB0J5k4iHmpNHZhJ0AiPG0E-hdMw2nAjhaKfJfpX56xAl5U3U0uwAOTc9NfirLojme-4rbMg==\" rel=\"nofollow noopener\" target=\"_blank\">www.sec.gov<\/a> and HOOKIPA\u2019s website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=V4rSrjORxWJaUKYbNi5YcTo9RFfteNTjJj_0yd3cwE5smfNs5gIlKPBDsQQnyGYTSr3hqJm51vkpeSeha1TiAVJ5i_gBDGe_t6nDgF-PA94=\" rel=\"nofollow noopener\" target=\"_blank\">www.hookipapharma.com<\/a>.<\/p>\n<p align=\"justify\">Investors and others should note that we announce material financial information to our investors using our investor relations website (<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=euZ3bvCNXD-9IoHUsmAsguy7Wtk0aeDxbkZVeWAK8f7YnVD38-Kwn05BIIbaCBC0i7dfjuEhQWPjRCN22nnJ10BAftnOLV_k4EZhj9OnSBX5Eg5NvCKVLiet0mWiEs4G7CN76v3PjJ0hktVTGyCQDUkCTRY3Yap3v4ineByXAL4k3vvZc0IOqdHHrDGvMQQ1ViPnORUPRj5sSi-940G1Fzt8E4OeODLiFLTmhHgVRa0O7A5xN4xdGCsScq1sRL-I4d0U37iJnt4Jogzyecvw6HRBsYPWCHE4NF_YnSRSzjA=\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/ir.hookipapharma.com\/<\/a>), SEC filings, press releases, public conference calls and webcasts. We use these channels, as well as social media, to communicate with our members and the public about our company, our services and other issues. It is possible that the information we post on social media could be deemed to be material information. Therefore, we encourage investors, the media, and others interested in our company to review the information we post on the U.S. social media channels listed on our investor relations website.<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"17\" style=\"vertical-align: bottom\">\n            <strong>HOOKIPA Pharma Inc.<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\" style=\"vertical-align: bottom\">\n            <strong>Consolidated Statements of Operations (Unaudited)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\" style=\"vertical-align: bottom\">\n            <strong>(In thousands, except share and per share data)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"7\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Three months ended December\u00a031,<\/strong><br \/>\n            <br \/>\n            <strong>(unaudited)\u00a0<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"7\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Year ended December\u00a031,\u00a0<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2022<\/strong>\n          <\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2021<\/strong><br \/>\n            \n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2022<\/strong><br \/>\n            \n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2021<\/strong><br \/>\n            \n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:44%;width:44%;min-width:44%;vertical-align: bottom\">Revenue from collaboration and licensing<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">7,828<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">3,895<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">14,249<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;vertical-align: bottom\">$<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">18,448<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Operating expenses:<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">Research and development<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(17,592<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(22,419<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(68,645<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(82,853<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: bottom\">General and administrative<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(3,824<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(3,523<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(18,759<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(17,269<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Total operating expenses<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(21,416<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(25,942<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(87,404<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(100,122<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Loss from operations<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(13,588<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(22,047<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(73,155<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(81,674<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Total interest, other income and taxes, net<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">1,277<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">812<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">8,240<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">6,009<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Net loss<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(12,311<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(21,235<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(64,915<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: double 15px 3pt;vertical-align: bottom\">$<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(75,665<\/td>\n<td style=\"border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Net loss per share \u2014 basic and diluted<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.17<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.65<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.99<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(2.30<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"9\">\n            <strong>Condensed Balance Sheets<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td colspan=\"9\">\n            <strong>(In thousands)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:71%;width:71%;min-width:71%\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%\">\u00a0<\/td>\n<td colspan=\"3\" style=\"max-width:12%;width:12%;min-width:12%\">\u00a0<\/td>\n<td style=\"max-width:2%;width:2%;min-width:2%\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%\">\u00a0<\/td>\n<td style=\"max-width:12%;width:12%;min-width:12%\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"3\" style=\"text-align: center;vertical-align: middle\">\n            <strong>As\u00a0of<\/strong>\n          <\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"text-align: center;vertical-align: middle\">\n            <strong>As\u00a0of<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"3\" style=\"text-align: center;vertical-align: middle\">\n            <strong>December\u00a031,\u00a0<\/strong>\n          <\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"text-align: center;vertical-align: middle\">\n            <strong>December\u00a031,\u00a0<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle\">\n            <strong>2022<\/strong>\n          <\/td>\n<td>\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle\">\n            <strong>2021<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td>Cash, cash equivalents and restricted cash<\/td>\n<td>\u00a0<\/td>\n<td>$<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle\">113,444<\/td>\n<td>\u00a0<\/td>\n<td>$<\/td>\n<td style=\"text-align: right;vertical-align: middle\">66,912<\/td>\n<\/tr>\n<tr>\n<td>Total assets<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle\">170,454<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle\">126,045<\/td>\n<\/tr>\n<tr>\n<td>Total liabilities<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle\">67,937<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle\">36,453<\/td>\n<\/tr>\n<tr>\n<td>Total stockholders\u2019 equity<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td colspan=\"3\" style=\"text-align: right;vertical-align: middle\">102,517<\/td>\n<td>\u00a0<\/td>\n<td>\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle\">89,592<\/td>\n<\/tr>\n<\/table>\n<p>\n        \n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td colspan=\"2\">For further information, please contact:<\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:50%;width:50%;min-width:50%\">\n            <strong>Media<\/strong>\n          <\/td>\n<td style=\"max-width:50%;width:50%;min-width:50%\">\n            <strong>Investors<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td>Instinctif Partners<\/td>\n<td>Matt Beck<\/td>\n<\/tr>\n<tr>\n<td>\n            <a href=\"mailto:hookipa@instinctif.com\" rel=\"nofollow noopener\" target=\"_blank\">hookipa@instinctif.com<\/a>\n          <\/td>\n<td>Executive Director &#8211; Investor Relations<\/td>\n<\/tr>\n<tr>\n<td>+44 (0) 7457 2020<\/td>\n<td>\n            <a href=\"mailto:matthew.beck@hookipapharma.com\" rel=\"nofollow noopener\" target=\"_blank\">matthew.beck@hookipapharma.com<\/a>\n          <\/td>\n<\/tr>\n<tr>\n<td>\u00a0<\/td>\n<td>+1 917 209 6886<\/td>\n<\/tr>\n<\/table>\n<p>      <img decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc4ODUzMiM1NDYyNTI4IzIxNTY5MjI=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" src=\"https:\/\/ml.globenewswire.com\/media\/YzFjYTdlYjItNWEzZC00OTZkLWIyYWItNmUyYzNmMGFhZjg0LTExNjg0OTM=\/tiny\/HOOKIPA-Pharma-Inc.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Data from Phase\u00a02 study of HB-200 in combination with pembrolizumab in head and neck cancers expected in 2Q 2023 Phase\u00a01 HB-300 trial in metastatic castration-resistant prostate cancer open for enrollment KRAS program (HB-700) achieved its first milestone payment in the Roche collaboration in February 2023; plan to submit IND in 1H 2024 Strengthened cash position of $113.4\u00a0million at year-end; additional $15.0\u00a0million cash inflow from collaboration milestones in early 2023 NEW YORK and VIENNA, March 15, 2023 (GLOBE NEWSWIRE) &#8212; HOOKIPA Pharma Inc. (NASDAQ: HOOK, \u2018HOOKIPA\u2019), a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform, today reported financial results and provided a corporate update for the fourth quarter and full year 2022, as well as the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-740172","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Data from Phase\u00a02 study of HB-200 in combination with pembrolizumab in head and neck cancers expected in 2Q 2023 Phase\u00a01 HB-300 trial in metastatic castration-resistant prostate cancer open for enrollment KRAS program (HB-700) achieved its first milestone payment in the Roche collaboration in February 2023; plan to submit IND in 1H 2024 Strengthened cash position of $113.4\u00a0million at year-end; additional $15.0\u00a0million cash inflow from collaboration milestones in early 2023 NEW YORK and VIENNA, March 15, 2023 (GLOBE NEWSWIRE) &#8212; HOOKIPA Pharma Inc. (NASDAQ: HOOK, \u2018HOOKIPA\u2019), a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform, today reported financial results and provided a corporate update for the fourth quarter and full year 2022, as well as the &hellip; Continue reading &quot;HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-03-15T11:04:41+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc4ODUzMiM1NDYyNTI4IzIxNTY5MjI=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"13 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook\",\"datePublished\":\"2023-03-15T11:04:41+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/\"},\"wordCount\":2523,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODc4ODUzMiM1NDYyNTI4IzIxNTY5MjI=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\\\/\",\"name\":\"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/","og_locale":"en_US","og_type":"article","og_title":"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook - Market Newsdesk","og_description":"Data from Phase\u00a02 study of HB-200 in combination with pembrolizumab in head and neck cancers expected in 2Q 2023 Phase\u00a01 HB-300 trial in metastatic castration-resistant prostate cancer open for enrollment KRAS program (HB-700) achieved its first milestone payment in the Roche collaboration in February 2023; plan to submit IND in 1H 2024 Strengthened cash position of $113.4\u00a0million at year-end; additional $15.0\u00a0million cash inflow from collaboration milestones in early 2023 NEW YORK and VIENNA, March 15, 2023 (GLOBE NEWSWIRE) &#8212; HOOKIPA Pharma Inc. (NASDAQ: HOOK, \u2018HOOKIPA\u2019), a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform, today reported financial results and provided a corporate update for the fourth quarter and full year 2022, as well as the &hellip; Continue reading \"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/","og_site_name":"Market Newsdesk","article_published_time":"2023-03-15T11:04:41+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc4ODUzMiM1NDYyNTI4IzIxNTY5MjI=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"13 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook","datePublished":"2023-03-15T11:04:41+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/"},"wordCount":2523,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODc4ODUzMiM1NDYyNTI4IzIxNTY5MjI=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/hookipa-reports-fourth-quarter-and-full-year-2022-financial-results-and-provides-2023-outlook\/","name":"HOOKIPA Reports Fourth Quarter and Full Year 2022 Financial Results\u00a0and Provides 2023 Outlook - 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