{"id":726198,"date":"2023-01-26T09:11:17","date_gmt":"2023-01-26T14:11:17","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/"},"modified":"2023-01-26T09:11:17","modified_gmt":"2023-01-26T14:11:17","slug":"centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/","title":{"rendered":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors"},"content":{"rendered":"<h2>\nLB101 is a conditionally tetravalent PD-L1xCD47\u00a0LockBody bispecific monoclonal antibody being developed for solid tumors<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"left\">BOSTON and LONDON, Jan.  26, 2023  (GLOBE NEWSWIRE) &#8212; <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ZX7eeGkruFhByHphJwWTPDeQ-tyGxansa2p_2Cvh5xPMv_xW7V0gKXbdxftkfUY-8Pzr57Jp78mpEwINhns_vblDKxpy24yUhcShS-XMfhc=\" rel=\"nofollow noopener\" target=\"_blank\">Centessa Pharmaceuticals plc<\/a> (Nasdaq: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, today announced that it has received clearance of its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1\/2a first-in-human, clinical trial of LB101 for the treatment of solid tumors. LB101, a conditionally tetravalent PD-L1xCD47\u00a0LockBody\u00ae bispecific monoclonal antibody targeting solid tumors, is the first product candidate developed using the Company\u2019s proprietary LockBody technology which is designed to selectively drive potent effector function activity, such as CD47, in the tumor microenvironment (TME) while avoiding systemic toxicity.\u00a0<\/p>\n<p>&#8220;We are very excited to be bringing our first LockBody candidate to the clinic and to be advancing a potentially transformative technology for patients with solid tumors,\u201d said Saurabh Saha MD PhD, Chief Executive Officer of Centessa. \u201cThe clearance of our IND for LB101 is an important milestone for our company as we have an ambitious strategy to advance multiple potential LockBody candidates in areas where there is a significant need for new cancer treatment options. We look forward to initiating the Phase 1\/2a trial of LB101 as soon as possible.\u201d<\/p>\n<p>\n        <strong>About LB101<\/strong><br \/>\n        <br \/>LB101 is a conditionally tetravalent PD-L1xCD47\u00a0LockBody bispecific monoclonal antibody which has two anti-CD47 domains blocked by two anti-PD-L1 domains, with proprietary human IgG-derived hinges linking the anti-CD47 and anti-PD-L1 domains. The cell-killing mechanism of action, CD47, is designed to be blocked by the PD-L1 tumor targeting domain until the IgG-derived hinges are naturally degraded in the TME, thus unlocking and activating the CD47 effector function activity in the tumor.<\/p>\n<p>\n        <strong>About Centessa Pharmaceuticals<\/strong><br \/>\n        <br \/>Centessa Pharmaceuticals plc is a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients. Our programs span discovery-stage to late-stage development and cover a range of high-value indications. We operate with the conviction that each one of our programs has the potential to change the current treatment paradigm and establish a new standard of care. For more information, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=vzWwf3ZnfpwtZ88ecpLANpzdx_pReKbrJu6z2ADFsELalrpKZp3WFmFbSn4B4Ye44RfhutyKcIbqVNF0fnEeURCdMUlWotVYEgP7OgrL_5M=\" rel=\"nofollow noopener\" target=\"_blank\">http:\/\/www.centessa.com\/<\/a>, which does not form part of this release.<\/p>\n<p>\n        <strong>Forward Looking Statements<\/strong><br \/>\n        <br \/>This press release contains forward-looking statements. These statements may be identified by words such as \u201cmay,\u201d \u201cmight,\u201d \u201cwill,\u201d \u201ccould,\u201d \u201cwould,\u201d \u201cshould,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cplan,\u201d \u201cobjective,\u201d \u201canticipate,\u201d \u201cbelieve,\u201d \u201cestimate,\u201d \u201cpredict,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201congoing,\u201d \u201caim,\u201d \u201cseek,\u201d and variations of these words or similar expressions that are intended to identify forward-looking statements. Any such statements in this press release that are not statements of historical fact may be deemed to be forward-looking statements, including statements related to the Company\u2019s ability to discover and develop transformational medicines for patients; the timing of commencement of new studies or clinical trials of LB101, the LockBody technology and other potential LockBody candidates; research and clinical development plans and the timing thereof; the Company\u2019s ability to differentiate LB101, the LockBody technology and\/or other potential LockBody candidates from other treatment options; the development and therapeutic potential of LB101, the LockBody technology and other potential LockBody candidates; and regulatory matters, including the timing and likelihood of success of obtaining authorizations to initiate or continue clinical trials. Any forward-looking statements in this press release are based on our current expectations, estimates and projections only as of the date of this release and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, risks related to the safety and tolerability profile of our product candidates; our ability to protect and maintain our intellectual property position; business (including commercial viability), regulatory, economic and competitive risks, uncertainties, contingencies and assumptions about the Company; risks inherent in developing product candidates and technologies; future results from our ongoing and planned clinical trials; our ability to obtain adequate financing, including through our financing facility with Oberland, to fund our planned clinical trials and other expenses; trends in the industry; the legal and regulatory framework for the industry, including the receipt and maintenance of clearances to conduct or continue clinical testing; future expenditures risks related to our asset-centric corporate model; the risk that any one or more of our product candidates will not be successfully developed and\/or commercialized; the risk that the results of preclinical studies or clinical studies will not be predictive of future results in connection with future studies; geo-political risks such as the Russia-Ukraine war and risks related to the ongoing COVID-19 pandemic including the effects of the Delta, Omicron and any other variants. These and other risks concerning our programs and operations are described in additional detail in our Annual Report on Form 10-K, Quarterly Reports on Form 10-Q, and our other reports, which are on file with the U.S. Securities and Exchange Commission (SEC). We explicitly disclaim any obligation to update any forward-looking statements except to the extent required by law.<\/p>\n<p>\n        <strong>Contact:<\/strong><br \/>\n        <br \/>Kristen K. Sheppard, Esq.<br \/>SVP of Investor Relations<br \/>investors@centessa.com\u00a0<\/p>\n<p>      <img decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" src=\"https:\/\/ml.globenewswire.com\/media\/ODI2OGFiNjMtMjg3Zi00NTFiLWFjNzktOTA1YmFiOGU2ZjY1LTEyMjEwMjA=\/tiny\/Centessa-Pharmaceuticals-plc.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>LB101 is a conditionally tetravalent PD-L1xCD47\u00a0LockBody bispecific monoclonal antibody being developed for solid tumors BOSTON and LONDON, Jan. 26, 2023 (GLOBE NEWSWIRE) &#8212; Centessa Pharmaceuticals plc (Nasdaq: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, today announced that it has received clearance of its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1\/2a first-in-human, clinical trial of LB101 for the treatment of solid tumors. LB101, a conditionally tetravalent PD-L1xCD47\u00a0LockBody\u00ae bispecific monoclonal antibody targeting solid tumors, is the first product candidate developed using the Company\u2019s proprietary LockBody technology which is designed to selectively drive potent effector function activity, such as CD47, in the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-726198","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"LB101 is a conditionally tetravalent PD-L1xCD47\u00a0LockBody bispecific monoclonal antibody being developed for solid tumors BOSTON and LONDON, Jan. 26, 2023 (GLOBE NEWSWIRE) &#8212; Centessa Pharmaceuticals plc (Nasdaq: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, today announced that it has received clearance of its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1\/2a first-in-human, clinical trial of LB101 for the treatment of solid tumors. LB101, a conditionally tetravalent PD-L1xCD47\u00a0LockBody\u00ae bispecific monoclonal antibody targeting solid tumors, is the first product candidate developed using the Company\u2019s proprietary LockBody technology which is designed to selectively drive potent effector function activity, such as CD47, in the &hellip; Continue reading &quot;Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2023-01-26T14:11:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\\\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors\",\"datePublished\":\"2023-01-26T14:11:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/\"},\"wordCount\":883,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/\",\"name\":\"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\\\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\",\"datePublished\":\"2023-01-26T14:11:17+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\",\"contentUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\\\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\",\"name\":\"Market Newsdesk\",\"description\":\"Latest Business News in Real Time\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\",\"name\":\"Newsdesk\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"caption\":\"Newsdesk\"},\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/author\\\/newsdesk\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/","og_locale":"en_US","og_type":"article","og_title":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk","og_description":"LB101 is a conditionally tetravalent PD-L1xCD47\u00a0LockBody bispecific monoclonal antibody being developed for solid tumors BOSTON and LONDON, Jan. 26, 2023 (GLOBE NEWSWIRE) &#8212; Centessa Pharmaceuticals plc (Nasdaq: CNTA), a clinical-stage pharmaceutical company that aims to discover and develop medicines that are transformational for patients, today announced that it has received clearance of its Investigational New Drug (IND) application from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1\/2a first-in-human, clinical trial of LB101 for the treatment of solid tumors. LB101, a conditionally tetravalent PD-L1xCD47\u00a0LockBody\u00ae bispecific monoclonal antibody targeting solid tumors, is the first product candidate developed using the Company\u2019s proprietary LockBody technology which is designed to selectively drive potent effector function activity, such as CD47, in the &hellip; Continue reading \"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/","og_site_name":"Market Newsdesk","article_published_time":"2023-01-26T14:11:17+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors","datePublished":"2023-01-26T14:11:17+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/"},"wordCount":883,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/","name":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors - Market Newsdesk","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#primaryimage"},"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=","datePublished":"2023-01-26T14:11:17+00:00","author":{"@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"breadcrumb":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#primaryimage","url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc=","contentUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODczNzMyMyM1Mzc2NTQ3IzIyMDk0Njc="},{"@type":"BreadcrumbList","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/centessa-pharmaceuticals-announces-fda-clearance-of-ind-application-for-phase-1-2a-clinical-trial-of-lb101-first-lockbody-candidate-for-solid-tumors\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.marketnewsdesk.com\/"},{"@type":"ListItem","position":2,"name":"Centessa Pharmaceuticals Announces FDA Clearance of IND Application for Phase 1\/2a Clinical Trial of LB101, First LockBody\u00ae Candidate, for Solid Tumors"}]},{"@type":"WebSite","@id":"https:\/\/www.marketnewsdesk.com\/#website","url":"https:\/\/www.marketnewsdesk.com\/","name":"Market Newsdesk","description":"Latest Business News in Real Time","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.marketnewsdesk.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979","name":"Newsdesk","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","caption":"Newsdesk"},"url":"https:\/\/www.marketnewsdesk.com\/index.php\/author\/newsdesk\/"}]}},"_links":{"self":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/726198","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/comments?post=726198"}],"version-history":[{"count":0,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/726198\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/media?parent=726198"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/categories?post=726198"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/tags?post=726198"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}