{"id":692302,"date":"2022-10-05T08:04:23","date_gmt":"2022-10-05T12:04:23","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/"},"modified":"2022-10-05T08:04:23","modified_gmt":"2022-10-05T12:04:23","slug":"monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/","title":{"rendered":"Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis"},"content":{"rendered":"

\nInterim Analysis Planned for Q1 2023
\n<\/h2>\n
\n

WILMETTE, Ill., Oct. 05, 2022 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR),\u00a0a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients,\u00a0today\u00a0announced an update on its actively enrolling Validive Phase 2b\/3 VOICE clinical trial for the prevention of severe oral mucositis (SOM) in patients undergoing chemoradiotherapy (CRT) for oropharyngeal cancer. This is an indication for which there is currently no FDA-approved preventative or treatment.<\/p>\n

Monopar announced it has enrolled greater than 130 patients, has completed enrollment for the Phase 2b portion of the trial, has activated a total of 68 sites, has recently expanded the trial to include sites in Germany and Poland, and has commenced enrollment for the Phase 3 portion of the trial. The blinded interim analysis of clinical data from the Phase 2b patient cohort of the trial, to be performed by an independent data monitoring board, will be used to guide the Company as to whether or not to continue enrolling the Phase 3 portion of the trial. This analysis should be complete with interim results announced during Q1 2023.<\/p>\n

\u201cIn planning for success for a potential positive go\/no-go outcome from the upcoming Q1 2023 interim analysis, we have been actively enrolling patients and adding clinical sites to the VOICE trial and expect to continue doing so,\u201d said Chandler Robinson, MD, Monopar\u2019s Chief Executive Officer. \u201cExpanding to include additional sites outside of the U.S. will dramatically increase the number of patients available for enrollment in the study.\u201d<\/p>\n

\n About Monopar Therapeutics Inc.<\/strong>\n <\/p>\n

Monopar Therapeutics is a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients. Monopar’s pipeline consists of Validive\u00ae<\/sup> for the prevention of chemoradiotherapy-induced severe oral mucositis in oropharyngeal cancer patients; camsirubicin for the treatment of advanced soft tissue sarcoma; a late-stage preclinical antibody, MNPR-101, for advanced cancers and severe COVID-19; and an early-stage camsirubicin analog, MNPR-202, for various cancers. For more information, visit: www.monopartx.com<\/u><\/a>.<\/p>\n

\n Forward-Looking Statements<\/strong>\n <\/p>\n

Statements contained in this press release regarding matters that are not historical facts are “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. The words \u201cmay,\u201d \u201cwill,\u201d \u201ccould,\u201d \u201cwould,\u201d \u201cshould,\u201d \u201cexpect,\u201d \u201cplan,\u201d \u201canticipate,\u201d \u201cintend,\u201d \u201cbelieve,\u201d \u201cestimate,\u201d \u201cpredict,\u201d \u201cproject,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201ctarget\u201d and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Examples of these forward-looking statements include statements concerning: that the VOICE trial\u2019s interim analysis is currently anticipated to be reached in the first quarter of 2023; that Monopar will continue to enroll patients and add sites to the VOICE trial; and that Monopar will activate additional clinical sites outside of the U.S. The forward-looking statements involve risks and uncertainties including, but not limited to: not successfully recruiting additional patients and initiating additional clinical trial sites for the VOICE clinical trial within expected timeframes, if at all; that the VOICE clinical trial may not reach interim analysis by the first quarter of 2023, if at all; the Company\u2019s inability to raise sufficient funds or engage a partner to complete the Phase 3 portion of the VOICE clinical trial; and the significant general risks and uncertainties surrounding the research, development, regulatory approval, and commercialization of therapeutics. Actual results may differ materially from those expressed or implied by such forward-looking statements. Risks are described more fully in Monopar’s filings with the Securities and Exchange Commission. All forward-looking statements contained in this press release speak only as of the date on which they were made. Monopar undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made. Any forward-looking statements contained in this press release represent Monopar\u2019s views only as of the date hereof and should not be relied upon as representing its views as of any subsequent date.<\/p>\n

\n CONTACT:<\/strong>\u202f<\/p>\n

\n Monopar Therapeutics Inc.<\/strong>\u00a0
Investor Relations\u202f
Kim R. Tsuchimoto\u202f
Chief Financial Officer\u202f
kimtsu@monopartx.com<\/u><\/a>\u00a0<\/p>\n

Follow Monopar on social media for updates:
Twitter:\u00a0@MonoparTx<\/u><\/a>\u202f LinkedIn:\u00a0Monopar Therapeutics<\/u><\/a><\/p>\n


\n
\n \n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

Interim Analysis Planned for Q1 2023 WILMETTE, Ill., Oct. 05, 2022 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. (Nasdaq: MNPR),\u00a0a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients,\u00a0today\u00a0announced an update on its actively enrolling Validive Phase 2b\/3 VOICE clinical trial for the prevention of severe oral mucositis (SOM) in patients undergoing chemoradiotherapy (CRT) for oropharyngeal cancer. This is an indication for which there is currently no FDA-approved preventative or treatment. Monopar announced it has enrolled greater than 130 patients, has completed enrollment for the Phase 2b portion of the trial, has activated a total of 68 sites, has recently expanded the trial to include sites in Germany and … <\/p>\n

Continue reading “Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-692302","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nMonopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Interim Analysis Planned for Q1 2023 WILMETTE, Ill., Oct. 05, 2022 (GLOBE NEWSWIRE) — Monopar Therapeutics Inc. 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(Nasdaq: MNPR),\u00a0a clinical-stage biopharmaceutical company focused on developing proprietary therapeutics designed to extend life or improve the quality of life for cancer patients,\u00a0today\u00a0announced an update on its actively enrolling Validive Phase 2b\/3 VOICE clinical trial for the prevention of severe oral mucositis (SOM) in patients undergoing chemoradiotherapy (CRT) for oropharyngeal cancer. This is an indication for which there is currently no FDA-approved preventative or treatment. Monopar announced it has enrolled greater than 130 patients, has completed enrollment for the Phase 2b portion of the trial, has activated a total of 68 sites, has recently expanded the trial to include sites in Germany and … Continue reading \"Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/","og_site_name":"Market Newsdesk","article_published_time":"2022-10-05T12:04:23+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODY1OTIwMSM1MTg3OTk5IzIxOTM4NjM=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis","datePublished":"2022-10-05T12:04:23+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/"},"wordCount":699,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODY1OTIwMSM1MTg3OTk5IzIxOTM4NjM=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/monopar-announces-completion-of-phase-2b-enrollment-and-commencement-of-phase-3-enrollment-in-its-voice-trial-for-severe-oral-mucositis\/","name":"Monopar Announces Completion of Phase 2b Enrollment and Commencement of Phase 3 Enrollment in its VOICE Trial for Severe Oral Mucositis - 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