{"id":525494,"date":"2021-08-09T13:16:59","date_gmt":"2021-08-09T17:16:59","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/nrx-pharmaceuticals-announces-initiation-of-phase-2b-trial-of-brilife-vaccine-for-covid-19-in-nation-of-georgia\/"},"modified":"2021-08-09T13:16:59","modified_gmt":"2021-08-09T17:16:59","slug":"nrx-pharmaceuticals-announces-initiation-of-phase-2b-trial-of-brilife-vaccine-for-covid-19-in-nation-of-georgia","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/nrx-pharmaceuticals-announces-initiation-of-phase-2b-trial-of-brilife-vaccine-for-covid-19-in-nation-of-georgia\/","title":{"rendered":"NRx Pharmaceuticals Announces Initiation of Phase 2b Trial of BriLife\u2122 Vaccine for Covid-19 in Nation of Georgia"},"content":{"rendered":"
\n

-Dose-Confirmatory Trial Follows Successful Phase 2a Trial<\/h2>\n

-Preclinical and Early Human Data Indicate BriLife\u2122 May Confer Enhanced Immunity Against Delta variant<\/h2>\n

PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n RADNOR, Pa.<\/span>, Aug. 9, 2021<\/span> \/PRNewswire\/ —\u00a0NRx Pharmaceuticals (NRx) (Nasdaq: NRXP), a clinical stage, global biopharmaceutical company today announced\u00a0it is initiating a phase 2b<\/span> dose-confirmatory trial of the BriLife\u2122 vaccine against COVID-19 in the Nation of Georgia.\u00a0 The vaccine is developed by the Israel Institute for Biological Research (IIBR).\u00a0 The trial is being conducted with oversight from the Senator Richard Lugar Center for Public Health Research. The purpose of the study is to confirm the vaccine’s ability to generate an immune response against the COVID-19 Delta variant, prior to entering phase 3 trials in multiple nations. The phase 2b<\/span> program will also incorporate a potential intradermal vaccination option where a small quantity of vaccine is placed into the skin instead of a traditional needle injection into a muscle.<\/p>\n

\n

\n
\n \"(PRNewsfoto\/NeuroRx)\"
\n <\/a>\n <\/p>\n<\/p><\/div>\n

NRx Pharmaceuticals Announces Initiation of Phase 2b<\/span> Trial of BriLife\u2122 Vaccine for Covid-19 in Nation of Georgia<\/span><\/div>\n

The vaccine differs from other COVID-19 vaccines by presenting the entire COVID-19 spike protein to the body’s immune system. The spike protein complex from variants may be added to the BriLife vaccine as new variants are discovered.<\/p>\n

The BriLife\u2122 vaccine also differs from other COVID-19 vaccine approaches in that it is a self-propagating, live-virus vaccine that may be updated to address new variants of COVID-19 more rapidly than some other vaccine platforms. The clinical trials in Georgia<\/span> will take place at the same time as the completion of the second phase of clinical trials in Israel<\/span>. NRx is recruiting volunteers, and expanding the second phase of clinical trials abroad, in order to increase the statistical sample and prepare the regulatory file necessary for further trials. <\/p>\n

A spokesperson for Israel’s<\/span> Minister of Defense stated today that, “IIBR will accompany the process and will continue to provide scientific knowledge in order to complete the trials.”<\/p>\n

“We at NRx are honored to have been selected for this project and grateful for the trust placed in us by the Government of Israel<\/span>, the people of Georgia<\/span>, and its neighboring countries,” said Prof Jonathan Javitt<\/span>, MD, MPH, CEO and Chairman of NRx. “As the Delta and subsequent variants continue to threaten the immunity generated by first-generation vaccines, we hope that this new vector-based approach may offer enhanced immunity.” <\/p>\n

\n
\n About NRx Pharmaceuticals<\/u>
\n <\/b>
\n
NRx Pharmaceuticals (www.nrxpharma.com<\/a>) (NRx) draws upon more than 300 years of collective, scientific and drug-development experience to bring improved health to patients. Its investigational product, ZYESAMI\u2122 (aviptadil) for patients with COVID-19, has been granted Fast Track designation by the US Food and Drug Administration (FDA) and is currently undergoing phase 3 trials funded by the US National Institutes of Health, the Biomedical Advanced Research and Development Authority part of the US Department of Health and Human Services, and the Medical Countermeasures program, part of the US Department of Defense. The FDA has additionally granted Breakthrough Therapy Designation, a Special Protocol Agreement, and a Biomarker Letter of Support to NRx for NRX-101, an investigational medicine to treat suicidal bipolar depression. NRX-101 is currently in Phase 3 trials, with readouts expected in 2022. In July 2021<\/span>, the Government of Israel<\/span> awarded NRx the exclusive worldwide right to develop and market the BriLife\u2122 COVID vaccine developed by the Israel Institute for Biological Research.<\/p>\n

NRx is led by executives who have held senior roles at Allergan, J&J, Lilly, Novartis, Pfizer, and the US FDA. NRx is chaired by\u00a0Prof Jonathan Javitt, MD, MPH, who has held leadership roles in six biotechnology startup companies with public exits and been appointed to advisory roles in four US Presidential administrations. The NRx board includes Dr.\u00a0Sherry Glied, former US Assistant Secretary for Health (ASPE),\u00a0Daniel E. Troy, JD, former Chief Counsel of the US FDA,\u00a0Chaim Hurvitz, former director of Teva and President of the Teva International Group, and General\u00a0H.R. McMaster, Ph.D. (US Army, Ret.) the 26th United States National Security Advisor.<\/p>\n

\n
\n Cautionary Note Regarding Forward-Looking Statements<\/u>
\n <\/b>\n <\/p>\n

This announcement of NRx Pharmaceuticals, Inc. includes “forward-looking statements” within the meaning of the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995, which may include, but are not limited to, statements regarding our financial outlook, product development, business prospects, and market and industry trends and conditions, as well as the company’s strategies, plans,\u00a0objectives,\u00a0and goals. These forward-looking statements are based on current beliefs, expectations, estimates,\u00a0forecasts,\u00a0and projections of, as well as assumptions made by, and information currently available to, the company’s management.\u00a0\u00a0\u00a0<\/p>\n

The company assumes no obligation to revise any forward-looking statement, whether\u00a0as a result of\u00a0new information, future events or otherwise.\u00a0\u00a0Accordingly, you should not place reliance on any forward-looking statement, and all forward-looking statements are herein qualified by reference to the cautionary statements set forth above.\u00a0<\/p>\n

\n\n\n\n\n\n\n\n
\n

\n
\n CORPORATE CONTACT<\/u>
\n <\/span>\n <\/p>\n<\/td>\n

\n \n <\/td>\n\n \n <\/td>\n\n

\n \u00a0INVESTOR RELATIONS<\/u><\/span>\n <\/p>\n<\/td>\n<\/tr>\n

\n

\n John Mullaly<\/span>\n <\/p>\n<\/td>\n<\/tr>\n

\n

\n Jack Hirschfield<\/span>\n <\/p>\n<\/td>\n<\/tr>\n

\n

\n Head of External Affairs, NRx<\/span>\n <\/p>\n<\/td>\n

\n

\n LifeSci Advisors<\/span>\n <\/p>\n<\/td>\n<\/tr>\n

\n

\n
\n jhirschfield@nrxpharma.com<\/a>
\n <\/span>\n <\/p>\n<\/td>\n

\n

\n
\n jmullaly@lifesciadvisors.com<\/a>
\n <\/span>\n <\/p>\n<\/td>\n<\/tr>\n

\n

\n 512-674-5163\u00a0<\/span>\n <\/p>\n<\/td>\n

\n

\n 617-429-3548<\/span>\n <\/p>\n<\/td>\n<\/tr>\n<\/table><\/div>\n

\u00a0<\/p>\n

<\/div>\n

\n \"Cision\" View original content to download multimedia:https:\/\/www.prnewswire.com\/news-releases\/nrx-pharmaceuticals-announces-initiation-of-phase-2b-trial-of-brilife-vaccine-for-covid-19-in-nation-of-georgia-301351289.html<\/a><\/p>\n

SOURCE NRx Pharmaceuticals<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

-Dose-Confirmatory Trial Follows Successful Phase 2a Trial -Preclinical and Early Human Data Indicate BriLife\u2122 May Confer Enhanced Immunity Against Delta variant PR Newswire RADNOR, Pa., Aug. 9, 2021 \/PRNewswire\/ —\u00a0NRx Pharmaceuticals (NRx) (Nasdaq: NRXP), a clinical stage, global biopharmaceutical company today announced\u00a0it is initiating a phase 2b dose-confirmatory trial of the BriLife\u2122 vaccine against COVID-19 in the Nation of Georgia.\u00a0 The vaccine is developed by the Israel Institute for Biological Research (IIBR).\u00a0 The trial is being conducted with oversight from the Senator Richard Lugar Center for Public Health Research. The purpose of the study is to confirm the vaccine’s ability to generate an immune response against the COVID-19 Delta variant, prior to entering phase 3 trials in multiple nations. The … <\/p>\n

Continue reading “NRx Pharmaceuticals Announces Initiation of Phase 2b Trial of BriLife\u2122 Vaccine for Covid-19 in Nation of Georgia”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-525494","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nNRx Pharmaceuticals Announces Initiation of Phase 2b Trial of BriLife\u2122 Vaccine for Covid-19 in Nation of Georgia - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/nrx-pharmaceuticals-announces-initiation-of-phase-2b-trial-of-brilife-vaccine-for-covid-19-in-nation-of-georgia\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"NRx Pharmaceuticals Announces Initiation of Phase 2b Trial of BriLife\u2122 Vaccine for Covid-19 in Nation of Georgia - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"-Dose-Confirmatory Trial Follows Successful Phase 2a Trial -Preclinical and Early Human Data Indicate BriLife\u2122 May Confer Enhanced Immunity Against Delta variant PR Newswire RADNOR, Pa., Aug. 9, 2021 \/PRNewswire\/ —\u00a0NRx Pharmaceuticals (NRx) (Nasdaq: NRXP), a clinical stage, global biopharmaceutical company today announced\u00a0it is initiating a phase 2b dose-confirmatory trial of the BriLife\u2122 vaccine against COVID-19 in the Nation of Georgia.\u00a0 The vaccine is developed by the Israel Institute for Biological Research (IIBR).\u00a0 The trial is being conducted with oversight from the Senator Richard Lugar Center for Public Health Research. 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The purpose of the study is to confirm the vaccine’s ability to generate an immune response against the COVID-19 Delta variant, prior to entering phase 3 trials in multiple nations. 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