{"id":519769,"date":"2021-07-29T07:33:54","date_gmt":"2021-07-29T11:33:54","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/"},"modified":"2021-07-29T07:33:54","modified_gmt":"2021-07-29T11:33:54","slug":"ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/","title":{"rendered":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021"},"content":{"rendered":"
\n

\n ACI-24 generated an encouraging immune response that correlated with a signal of target engagement in patients with Down syndrome (DS)<\/em>
\n \n <\/p>\n

\n Full Phase 1b results support the continued clinical development of anti-Abeta vaccine approaches in DS-related Alzheimer\u2019s disease (AD)<\/em>\n <\/p>\n

LAUSANNE, Switzerland, July 29, 2021 (GLOBE NEWSWIRE) — AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today outlined two presentations being delivered at the Alzheimer\u2019s Association International Conference<\/a> (AAIC) 2021, taking place both in Denver, USA and virtually from July 26-30, 2021.<\/p>\n

The presentations highlight precision medicine approaches to enable the early detection and prevention of neurodegenerative diseases by targeting amyloid beta (Abeta) and alpha-synuclein (a-syn). The first virtual oral presentation includes the full results from a first-of-its-kind Phase 1b clinical trial evaluating the anti-Abeta vaccine ACI-24 in adults with DS. Previously announced topline data<\/a> from the trial showed that ACI-24 generated evidence of immunogenicity along with a positive pharmacodynamic response and a favorable safety and tolerability profile.<\/p>\n

The Phase 1b study results showed that ACI-24 was safe and well tolerated in adults with DS. No serious adverse events or evidence of central nervous system (CNS) inflammation, meningoencephalitis, or ARIA (amyloid-related imaging abnormalities), including ARIA-E (edema) and ARIA-H (hemorrhage), were reported. Data also showed that administration of ACI-24 resulted in encouraging immune responses that correlated with increases in plasma Abeta, which are indicative of target engagement.<\/p>\n

\n Dr. Michael Rafii, Medical Director of the Alzheimer\u2019s Therapeutic Research Institute and Associate Professor of Neurology at the Keck School of Medicine, Lead Investigator of the study, commented: <\/strong>\u201cIndividuals with DS represent a homogenous genetic population that are predisposed to AD, which highlights the value of this landmark Phase 1b study and the innovation in AC Immune\u2019s approach. Importantly, the results of this study show a signal of target engagement that correlates with immune response against Abeta and support the continued evaluation of anti-Abeta vaccine approaches in these patients. This may enable a shift towards earlier treatment and ultimately prevention of AD, and would be a critical advance as the damage neurons undergo in neurodegenerative diseases cannot be reversed by currently available therapies.\u201d<\/p>\n

\n Prof.\u00a0Andrea Pfeifer, CEO of\u00a0AC Immune SA, commented: <\/strong>\u201cThe full data set from our Phase 1b DS study are promising and highlight AC Immune\u2019s expertise in active vaccination approaches for neurodegenerative disease. Based on these results, we plan to advance an optimized formulation of ACI-24 into late-stage clinical testing to treat and prevent the progression of DS-related AD. This formulation has demonstrated enhanced immunogenicity against the two most toxic Abeta species in non-human primates, positioning it to be a potential breakthrough in Abeta vaccination. We look forward to the program\u2019s continued advancement, which we believe will be accelerated by the recent validation of Abeta as a surrogate trial endpoint in AD.\u201d<\/p>\n

\n Prof. Johannes Streffer, CMO of AC Immune SA, commented: <\/strong>\u201cThrough an active vaccination approach, we aim to prevent neurodegeneration rather than simply slow its progression. As almost all subjects with DS go on to develop AD-like symptoms, this is an ideal patient population in which to gain critical insights and expertise into the development of vaccines for a variety of neurodegenerative diseases. We thus expect the promising results and learnings from this trial to accelerate the advancement of not only our ACI-24 program, but our entire world-leading pipeline of active vaccines for neurodegeneration.\u201d \u00a0\u00a0\u00a0<\/p>\n

In addition, AC Immune is also presenting a poster on ACI-12589, a first-in-class positron emission tomography (PET) imaging tracer targeting a-syn that is being developed as a first-in-class diagnostic for Parkinson\u2019s disease (PD). Previously reported preclinical data confirm that the Morphomer\u00ae-derived candidate has a desirable brain-PET ligand pharmacokinetic profile in non-human primates. These and other prior data demonstrating ACI-12589\u2019s signal specificity on tissue samples from patients with alpha-synucleinopathies, including PD, multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) are being discussed in this poster presentation.<\/p>\n

\n Prof.\u00a0Pfeifer continued,<\/strong> \u201cThrough the development of companion diagnostics such as ACI-12589 in PD, we are working to better enable the advancement of the neurodegenerative disease treatment paradigm towards earlier treatment and prevention. We expect the continued development of this program, alongside the advancement of our recently acquired industry-leading anti-a-syn vaccine, to solidify our position at the forefront of PD drug development. We are pleased to have the opportunity to discuss ACI-12589 with the scientific community at AAIC ahead of the anticipated readout from its first-in-human study later this quarter.\u201d<\/p>\n

\n Scientific updates at AAIC, July 26\u201330, 2021<\/strong>\n <\/p>\n\n\n\n\n\n\n\n\n
Title:<\/td>\nACI-24 in adults with Down syndrome: Results of a Phase 1b, randomized, placebo-controlled study (3 Star Trial)<\/td>\n<\/tr>\n
Date:<\/td>\nThursday, July 29, 2021 | 10:00 am – 11:15 pm MT<\/td>\n<\/tr>\n
Presenter:<\/td>\nOral presentation by Dr. Michael S. Rafii, Alzheimer\u2019s Therapeutic Research Institute, Keck School of Medicine of University of Southern California<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
Title:<\/td>\n[18F]ACI-12589, a novel alpha-synuclein radiotracer as a biomarker in patients with Parkinson\u2019s disease and other synucleinopathies<\/td>\n<\/tr>\n
Date:<\/td>\nJuly 26\u201330, 2021\u00a0\u00a0<\/td>\n<\/tr>\n
Presenter:<\/td>\nPoster presentation by Dr. Francesca Capotosti, AC Immune SA<\/td>\n<\/tr>\n<\/table>\n

\n About AC Immune SA
<\/strong>AC Immune SA is clinical-stage biopharmaceutical company that aims to become a global leader in precision medicine for neurodegenerative diseases, including Alzheimer\u2019s disease, Parkinson\u2019s disease, and NeuroOrphan indications driven by misfolded proteins. The Company\u2019s two clinically validated technology platforms, SupraAntigen\u00ae\u00a0and Morphomer\u00ae, fuel its broad and diversified pipeline of first- and best-in-class assets, which currently features ten therapeutic and three diagnostic candidates, six of which are currently in clinical trials. AC Immune has a strong track record of securing strategic partnerships with leading global pharmaceutical companies including Genentech, a member of the Roche Group, Eli Lilly and Company, and Janssen Pharmaceuticals, Inc., resulting in substantial non-dilutive funding to advance its proprietary programs and >$3 billion in potential milestone payments.<\/p>\n

SupraAntigen\u00ae and Morphomer\u00ae are registered trademarks of AC Immune SA in the following territories: AU, CH, EU, JP, and GB. Morphomer\u00ae is also a registered trademark of AC Immune SA in CN and NO.<\/p>\n

\n For further information, please contact:<\/strong>\n <\/p>\n\n\n\n
\n Media Relations<\/strong>
\n
Saoyuth Nidh
AC Immune
Phone: +41 21 345 91 34
Email: saoyuth.nidh@acimmune.com<\/a><\/p>\n<\/td>\n		\n Investor Relations<\/strong>
\n
Yves Kremer, Ph.D.
AC Immune
Phone: +41 21 345 91 90
Email: yves.kremer@acimmune.com<\/a><\/p>\n<\/td>\n<\/tr>\n
\n U.S. Media<\/strong>
\n
Katie Gallagher
LaVoie Health Science
Phone: +1 617 792 3937
Email: kgallagher@lavoiehealthscience.com<\/a><\/td>\n		\n U.S. Investors<\/strong>
\n
Chris Maggos
LifeSci Advisors
Phone: +1 917 809 0814
Email: chris@lifesciadvisors.com<\/a><\/p>\n<\/td>\n<\/tr>\n<\/table>\n

\n Forward-looking statements<\/strong>
\n
This press release contains statements that constitute \u201cforward-looking statements\u201d within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Forward-looking statements are statements other than historical fact and may include statements that address future operating, financial or business performance or AC Immune\u2019s strategies or expectations. In some cases, you can identify these statements by forward-looking words such as \u201cmay,\u201d \u201cmight,\u201d \u201cwill,\u201d \u201cshould,\u201d \u201cexpects,\u201d \u201cplans,\u201d \u201canticipates,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cpredicts,\u201d \u201cprojects,\u201d \u201cpotential,\u201d \u201coutlook\u201d or \u201ccontinue,\u201d and other comparable terminology. Forward-looking statements are based on management\u2019s current expectations and beliefs and involve significant risks and uncertainties that could cause actual results, developments and business decisions to differ materially from those contemplated by these statements. These risks and uncertainties include those described under the captions \u201cItem 3. Key Information \u2013 Risk Factors\u201d and \u201cItem 5. Operating and Financial Review and Prospects\u201d in AC Immune\u2019s Annual Report on Form 20-F and other filings with the Securities and Exchange Commission. These include: the impact of Covid-19 on our business, suppliers, patients and employees and any other impact of Covid-19. Forward-looking statements speak only as of the date they are made, and AC Immune does not undertake any obligation to update them in light of new information, future developments or otherwise, except as may be required under applicable law. All forward-looking statements are qualified in their entirety by this cautionary statement.<\/p>\n

\n
\n
\n \n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

ACI-24 generated an encouraging immune response that correlated with a signal of target engagement in patients with Down syndrome (DS) Full Phase 1b results support the continued clinical development of anti-Abeta vaccine approaches in DS-related Alzheimer\u2019s disease (AD) LAUSANNE, Switzerland, July 29, 2021 (GLOBE NEWSWIRE) — AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today outlined two presentations being delivered at the Alzheimer\u2019s Association International Conference (AAIC) 2021, taking place both in Denver, USA and virtually from July 26-30, 2021. The presentations highlight precision medicine approaches to enable the early detection and prevention of neurodegenerative diseases by targeting amyloid beta (Abeta) and alpha-synuclein (a-syn). The first virtual oral presentation includes the full results … <\/p>\n

Continue reading “AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-519769","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nAC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"ACI-24 generated an encouraging immune response that correlated with a signal of target engagement in patients with Down syndrome (DS) Full Phase 1b results support the continued clinical development of anti-Abeta vaccine approaches in DS-related Alzheimer\u2019s disease (AD) LAUSANNE, Switzerland, July 29, 2021 (GLOBE NEWSWIRE) — AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today outlined two presentations being delivered at the Alzheimer\u2019s Association International Conference (AAIC) 2021, taking place both in Denver, USA and virtually from July 26-30, 2021. The presentations highlight precision medicine approaches to enable the early detection and prevention of neurodegenerative diseases by targeting amyloid beta (Abeta) and alpha-synuclein (a-syn). The first virtual oral presentation includes the full results … Continue reading "AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-07-29T11:33:54+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021\",\"datePublished\":\"2021-07-29T11:33:54+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/\"},\"wordCount\":1289,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/\",\"name\":\"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==\",\"datePublished\":\"2021-07-29T11:33:54+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==\",\"contentUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\",\"name\":\"Market Newsdesk\",\"description\":\"Latest Business News in Real Time\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\",\"name\":\"Newsdesk\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"caption\":\"Newsdesk\"},\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/author\\\/newsdesk\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/","og_locale":"en_US","og_type":"article","og_title":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk","og_description":"ACI-24 generated an encouraging immune response that correlated with a signal of target engagement in patients with Down syndrome (DS) Full Phase 1b results support the continued clinical development of anti-Abeta vaccine approaches in DS-related Alzheimer\u2019s disease (AD) LAUSANNE, Switzerland, July 29, 2021 (GLOBE NEWSWIRE) — AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, today outlined two presentations being delivered at the Alzheimer\u2019s Association International Conference (AAIC) 2021, taking place both in Denver, USA and virtually from July 26-30, 2021. The presentations highlight precision medicine approaches to enable the early detection and prevention of neurodegenerative diseases by targeting amyloid beta (Abeta) and alpha-synuclein (a-syn). The first virtual oral presentation includes the full results … Continue reading \"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/","og_site_name":"Market Newsdesk","article_published_time":"2021-07-29T11:33:54+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021","datePublished":"2021-07-29T11:33:54+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/"},"wordCount":1289,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/","name":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021 - Market Newsdesk","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#primaryimage"},"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==","datePublished":"2021-07-29T11:33:54+00:00","author":{"@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"breadcrumb":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#primaryimage","url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ==","contentUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4OTIxMyM0MzIwNzI4IzUwMDA2NDA0MQ=="},{"@type":"BreadcrumbList","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-presents-full-phase-1b-results-on-anti-abeta-vaccine-and-discusses-its-first-in-class-diagnostic-for-parkinsons-disease-at-aaic-2021\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.marketnewsdesk.com\/"},{"@type":"ListItem","position":2,"name":"AC Immune Presents Full Phase 1b Results on Anti-Abeta Vaccine and Discusses its First-in-Class Diagnostic for Parkinson\u2019s Disease at AAIC 2021"}]},{"@type":"WebSite","@id":"https:\/\/www.marketnewsdesk.com\/#website","url":"https:\/\/www.marketnewsdesk.com\/","name":"Market Newsdesk","description":"Latest Business News in Real Time","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.marketnewsdesk.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979","name":"Newsdesk","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","caption":"Newsdesk"},"url":"https:\/\/www.marketnewsdesk.com\/index.php\/author\/newsdesk\/"}]}},"_links":{"self":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/519769","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/comments?post=519769"}],"version-history":[{"count":0,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/519769\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/media?parent=519769"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/categories?post=519769"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/tags?post=519769"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}