{"id":518080,"date":"2021-07-27T08:04:46","date_gmt":"2021-07-27T12:04:46","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-acquires-affiris-specific-active-immunotherapy-sait-anti-alpha-synuclein-programs-targeting-neurodegenerative-diseases\/"},"modified":"2021-07-27T08:04:46","modified_gmt":"2021-07-27T12:04:46","slug":"ac-immune-acquires-affiris-specific-active-immunotherapy-sait-anti-alpha-synuclein-programs-targeting-neurodegenerative-diseases","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-acquires-affiris-specific-active-immunotherapy-sait-anti-alpha-synuclein-programs-targeting-neurodegenerative-diseases\/","title":{"rendered":"AC Immune acquires AFFiRiS\u2019 Specific Active Immunotherapy (SAIT) anti-alpha-synuclein programs targeting neurodegenerative diseases"},"content":{"rendered":"<div class=\"mw_release\">\n<ul type=\"disc\">\n<li style=\"margin-bottom:8pt;text-align:justify\">\n          <strong>AFFiRiS to receive AC Immune stock valued at USD 58.7 million in exchange for its portfolio of therapeutics targeting alpha-synuclein and USD 5 million in cash<\/strong>\n        <\/li>\n<li style=\"margin-bottom:8pt;text-align:justify\">\n          <strong>AFFiRiS to focus on partnering to further develop its SAIT and monoclonal antibody for cardiovascular disease and for Huntington\u2019s disease, respectively<\/strong>\n        <\/li>\n<\/ul>\n<p align=\"justify\">VIENNA, Austria, July  27, 2021  (GLOBE NEWSWIRE) &#8212; AFFiRiS AG, a clinical-stage biotechnology company that has been engaged in the development of novel disease-modifying Specific Active Immunotherapies (SAITs), today announced that AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, is acquiring AFFiRiS\u2019 anti-alpha-synuclein programs targeting neurodegenerative diseases caused by misfolded forms of human self-proteins. All acquired programs are based on AFFiRiS\u00b4 AFFITOME<sup>\u00ae<\/sup> technology.<\/p>\n<p align=\"justify\">The all-stock acquisition is valued at USD 58.7 million. Under the terms of the agreement, AC Immune is acquiring all of AFFiRiS\u00b4 assets and underlying intellectual property related to active vaccine candidates targeting alpha-synuclein and USD 5 million in cash for 7.1 million shares of AC Immune common stock based on a price of USD 8.26 per common share.<\/p>\n<p align=\"justify\">\u201cWe are delighted that AC Immune, a company with complementary active immunotherapies, will further advance our industry-leading anti-alpha-synuclein vaccine candidate, developed to slow the progression of disease and help to improve the lives of patients. On the back of our encouraging published data from Phase 1 clinical studies in Parkinson\u2019s disease and multiple system atrophy (MSA), and preclinical proof of principle data in dementia with Lewy bodies (DLB), now was the right time to generate value from these programs through an asset sale,\u201d commented <strong>Noel Barrett, PhD, CEO of AFFiRiS AG<\/strong>. \u201cThe acquisition of these programs by this pioneer in precision medicine and active vaccination for neurodegenerative diseases validates our AFFITOME<sup>\u00ae<\/sup> technology platform and the development projects based on it.\u201d He added: \u201cThe transaction also allows us to focus on the partnering for further development of AFFiRiS\u2019 other programs in cardiometabolic and neurodegenerative disease indications, such as candidates targeting PCSK9 in hypercholesterolemia and the monoclonal antibody C6-17 to treat Huntington\u2019s disease.\u201d<\/p>\n<p align=\"justify\">\u201cAs long-term investors in AFFiRiS, we are confident that AFFiRiS\u2019 active immunotherapy program will favourably contribute to AC Immune\u2019s portfolio of transformative medicines by delivering much needed patient-friendly, highly innovative disease-modifying therapies to patients suffering from neurodegenerative diseases,\u201d added <strong>Michael Motschmann<\/strong>, <strong>Chairman of AFFiRiS\u2019 Supervisory Board and General Partner of MIG AG<\/strong>, one of the founding investors of AFFiRiS.<\/p>\n<p align=\"justify\">The acquisition is subject to customary regulatory approval in Austria and expected to complete at the beginning of Q4 2021.<\/p>\n<p align=\"justify\">\n        <strong>About AFFiRiS AG:<\/strong>\n      <\/p>\n<p align=\"justify\">AFFiRiS is a clinical-stage biotechnology company located in Vienna, Austria, with a vision of using the immune system to identify and target human proteins central to the development and progression of neurodegenerative and cardiometabolic diseases, based on its proprietary patented AFFITOME<sup>\u00ae<\/sup> technology. The Company\u2019s ultimate goal is to improve the lives of patients suffering from these diseases by providing specific immunotherapies.<\/p>\n<p align=\"justify\">Following the sale of its SAIT anti-alpha-synuclein programs to AC Immune in an all-stock transaction, AFFiRiS will concentrate on partnering activities to facilitate the further development of its programs in cardiovascular and neurodegenerative disease indications. AFFiRiS published positive Phase 1 clinical results with active immunotherapies targeting PCSK9 to treat the cardiovascular condition hypercholesterolemia. In addition, AFFiRiS will focus on partnering activities to enable the further development of the monoclonal antibody mAB C6-17 targeting mutated huntingtin (mtHTT) protein, which causes Huntington\u2019s disease. This is a neurodegenerative, hereditary disease characterized by changes in personality, cognitive impairment and loss of motor function, leading to death over a period of 10 to 30 years.<\/p>\n<p align=\"justify\">For further information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ZLCqMEJ2xnmMDtFqh_7xFnxwth3PRpfeP2pOD5zZhz8ISsBOHX0o9OlWNd2cxxGFQ9fZUaHo-71PPqSRYSXjIA==\" rel=\"nofollow noopener\" target=\"_blank\">www.affiris.com<\/a> and follow us on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Z1C1B2VUb0e41GiXi6FiTka3quq7gE_aU0ea4_72uvu0K0S4nDQwWF3YDAkmWvT7DjAqfNtAUmMYgww0DRYVhuH_hThItjimRbcHt4XQcMs=\" rel=\"nofollow noopener\" target=\"_blank\">LinkedIn<\/a> and <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=dGVkaeDu9fl_PFrv0drSoY9o6rWLAor_QS1290ur9gJm5RMYAy3AK8OIH4PDzdo58a6yRxNp1Fcj92MHS4QCGQ==\" rel=\"nofollow noopener\" target=\"_blank\">Twitter<\/a>.<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"max-width:30%;width:30%;min-width:30%\">\n            <strong>Contact AFFiRiS AG:<\/strong>\n          <\/td>\n<td style=\"max-width:70%;width:70%;min-width:70%\">\n            <strong>Media contact:<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td>Dr. Cornelia Kutzer<\/td>\n<td>MC Services<\/td>\n<\/tr>\n<tr>\n<td>Communication and Business Development<\/td>\n<td>Julia Hofmann<\/td>\n<\/tr>\n<tr>\n<td>E <a href=\"mailto:cornelia.kutzer@affiris.com\" rel=\"nofollow noopener\" target=\"_blank\">cornelia.kutzer@affiris.com<\/a><\/td>\n<td>P +49 89 210228 0<\/td>\n<\/tr>\n<tr>\n<td>W <a href=\"http:\/\/www.affiris.com\" rel=\"nofollow noopener\" target=\"_blank\">www.affiris.com<\/a><\/td>\n<td>E <a href=\"mailto:affiris@mc-services.eu\" rel=\"nofollow noopener\" target=\"_blank\">affiris@mc-services.eu<\/a><\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <strong>About SAIT:<br \/><\/strong><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UeAK4HJDJNOBzcqjFdWex2PylJNlYsSXhVEqVT-s_OXAsBND6fkoIGwrAxv1nGQzAGvhJS5XKFqTFjTtZy-jihVVWMFYrKFIi8t_NM39FUtnuBQnIgLwN9pTEQBXxIctOcQEjdZ-zoXYTu4sUzfx7C_2FtjWjTZOti48KzAl1GU=\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/affiris.com\/approach\/#overview-of-sait<\/a>\n      <\/p>\n<p>\n        <strong>About neurodegenerative diseases:<\/strong><br \/>\n        <br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UeAK4HJDJNOBzcqjFdWex-k5jXnCFL2AVmrhNtHIJekJ8TWYUERdXd0WXw8Y-xpe-nD700FrcMb3SRdGssPEGzSliPBVkQXkOZFDWyDrygz--UYFAA-hF4bNgp-tDTlE74Per962CuntjP_xtq2Whom8A12nhJn7QWCcJJNDtG4=\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/affiris.com\/neurodegenerative-diseases<\/a>\n      <\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI4NzM5MSM0MzE2NTc4IzUwMDA3OTYxOA==\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/589018be-4f59-4d19-8aa0-14e5d0815243\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>AFFiRiS to receive AC Immune stock valued at USD 58.7 million in exchange for its portfolio of therapeutics targeting alpha-synuclein and USD 5 million in cash AFFiRiS to focus on partnering to further develop its SAIT and monoclonal antibody for cardiovascular disease and for Huntington\u2019s disease, respectively VIENNA, Austria, July 27, 2021 (GLOBE NEWSWIRE) &#8212; AFFiRiS AG, a clinical-stage biotechnology company that has been engaged in the development of novel disease-modifying Specific Active Immunotherapies (SAITs), today announced that AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, is acquiring AFFiRiS\u2019 anti-alpha-synuclein programs targeting neurodegenerative diseases caused by misfolded forms of human self-proteins. All acquired programs are based on AFFiRiS\u00b4 AFFITOME\u00ae technology. The all-stock acquisition &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-acquires-affiris-specific-active-immunotherapy-sait-anti-alpha-synuclein-programs-targeting-neurodegenerative-diseases\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;AC Immune acquires AFFiRiS\u2019 Specific Active Immunotherapy (SAIT) anti-alpha-synuclein programs targeting neurodegenerative diseases&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-518080","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>AC Immune acquires AFFiRiS\u2019 Specific Active Immunotherapy (SAIT) anti-alpha-synuclein programs targeting neurodegenerative diseases - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/ac-immune-acquires-affiris-specific-active-immunotherapy-sait-anti-alpha-synuclein-programs-targeting-neurodegenerative-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"AC Immune acquires AFFiRiS\u2019 Specific Active Immunotherapy (SAIT) anti-alpha-synuclein programs targeting neurodegenerative diseases - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"AFFiRiS to receive AC Immune stock valued at USD 58.7 million in exchange for its portfolio of therapeutics targeting alpha-synuclein and USD 5 million in cash AFFiRiS to focus on partnering to further develop its SAIT and monoclonal antibody for cardiovascular disease and for Huntington\u2019s disease, respectively VIENNA, Austria, July 27, 2021 (GLOBE NEWSWIRE) &#8212; AFFiRiS AG, a clinical-stage biotechnology company that has been engaged in the development of novel disease-modifying Specific Active Immunotherapies (SAITs), today announced that AC Immune SA (NASDAQ: ACIU), a clinical-stage biopharmaceutical company pioneering precision medicine for neurodegenerative diseases, is acquiring AFFiRiS\u2019 anti-alpha-synuclein programs targeting neurodegenerative diseases caused by misfolded forms of human self-proteins. All acquired programs are based on AFFiRiS\u00b4 AFFITOME\u00ae technology. 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All acquired programs are based on AFFiRiS\u00b4 AFFITOME\u00ae technology. 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