{"id":499824,"date":"2021-06-01T07:08:07","date_gmt":"2021-06-01T11:08:07","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\/"},"modified":"2021-06-01T07:08:07","modified_gmt":"2021-06-01T11:08:07","slug":"corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\/","title":{"rendered":"Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases"},"content":{"rendered":"<div class=\"mw_release\">\n<ul type=\"disc\">\n<li>Corbus diversifies pipeline with two new mAbs that target integrins that inhibit activation of TGF\u03b2<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li>High potency anti-\ufeff\u03b1\ufeffv\u03b28\u00a0mAb\u00a0licensed from University of California San Francisco\u00a0and <br \/>anti-\u03b1v\u03b26\/\u03b1v\u03b28 mAb licensed from Panorama Research Inc.<\/li>\n<\/ul>\n<ul type=\"disc\">\n<li style=\"margin-bottom:8pt\">Both mAbs expected to start Phase 1 testing in 2022<\/li>\n<li style=\"margin-bottom:8pt\">Capital and resources in place to advance multiple programs into clinical development<\/li>\n<li style=\"margin-bottom:8pt\">Company to host conference call and webcast today, Tuesday, June 1, 2021 at 8:30 a.m. ET<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Norwood, MA, June  01, 2021  (GLOBE NEWSWIRE) &#8212; <\/strong>Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (\u201cCorbus\u201d or the \u201cCompany\u201d), today announced licensing deals for two new monoclonal antibodies (mAbs), CRB-601 and CRB-602, that target integrins to inhibit activation of transforming growth factor \u03b2 (TGF\u03b2). This new integrin program, in addition to the existing endocannabinoid system program, strengthens and diversifies Corbus\u2019 immunology pipeline for inflammatory, fibrotic, and metabolic diseases, and cancer. With these additions, Corbus expects to have four compounds other than lenabasum in Phase 1 testing in 2022.<\/p>\n<p align=\"justify\">\n        <strong>Targeting integrins to inhibit TGF\u03b2\u00a0<\/strong><br \/>\n        <strong>activation <\/strong>\n      <\/p>\n<p align=\"justify\">TGF\u03b2 is a multifunctional cytokine involved in many cellular processes, including cell growth and differentiation, immune responses, wound healing, and tissue repair. TGF\u03b2 plays a key role in fibrosis and also promotes cancer growth and metastasis via its effects in the tumor microenvironment (TME). The integrins \u03b1v\u03b26 and \u03b1v\u03b28 are expressed by cancer cells, and \u03b1v\u03b26 is also expressed on epithelial cells in fibrotic diseases. These integrins enable TGF\u03b2 to exert its biologic effects by releasing it from its latent complex. The goal of blocking these integrins is to inhibit the deleterious effects of TGF\u03b2. A number of other preclinical and early clinical stage programs are testing this approach of inhibiting \u03b1v integrins.<\/p>\n<p align=\"justify\">\n        <strong>CRB-601 and CRB-602 are two novel and distinct anti-integrin <\/strong><br \/>\n        <strong>mAbs<\/strong><br \/>\n        <strong>: <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"text-align:justify\">CRB-601 is an anti-\ufeff\u03b1\ufeffv\u03b28\u00a0mAb rationally designed by Dr. Stephen Nishimura and his colleagues at the University of California San Francisco and is potent at picomolar concentrations in inhibiting activation of TGF\u03b2. C6D4, the parent mAb of CRB-601, has single agent activity as well as synergistic activity when combined with an anti-PD1 mAb in syngeneic mouse tumor models. Corbus plans to develop CRB-601 for treatment of solid tumors in combination with existing therapies, including checkpoint inhibitors. Phase 1 studies are expected to start in 2022.<\/li>\n<li style=\"text-align:justify\">CRB-602 was developed by Panorama Research Inc. to specifically inhibit both \u03b1v\u03b26 and \u03b1v\u03b28. Both \u03b1v\u03b26 and \u03b1v\u03b28 have been implicated in fibrotic diseases and in cancers of epithelial cell origin. Corbus believes targeting both integrins at once is a rational approach to treating fibrotic diseases and carcinomas. Phase 1 studies are expected to start in 2022.<\/li>\n<\/ul>\n<p align=\"justify\">\u201cWe look forward to a strong partnership with Corbus and hope to see our mAb make a positive impact on the lives of cancer patients all over the world,\u201d said Anthony Francis, Executive Director of Technology Management at UCSF Innovation Ventures.<\/p>\n<p align=\"justify\">\u201cCorbus is committed to developing new medicines to improve the lives of people who need them,\u201d stated Yuval Cohen, Ph.D., Chief Executive Officer.\u00a0\u201cWe believe these two new\u00a0integrin-targeting mAbs offer a promising approach to inhibiting TGF\u03b2, fit well with our expertise in immunology, and diversify and expand our pipeline.\u00a0We plan to advance up to four new programs into the clinic next year and have the capital and resources to do so.\u201d\u00a0<\/p>\n<p align=\"justify\">The\u00a0Company\u2019s $125\u00a0million\u00a0of cash\u00a0and investments\u00a0on hand, as of\u00a0March\u00a031, 2021, is expected to fund operations\u00a0into the\u00a0first\u00a0quarter of\u00a02024,\u00a0based on the current planned expenditures.\u00a0<\/p>\n<p align=\"justify\">\n        <strong>Transactions Terms and Conditions:<\/strong>\n      <\/p>\n<p align=\"justify\">Under the combined terms of the two exclusive licensing agreements, Corbus will pay $2,000,000 upfront and will make potential development and sales milestone payments totaling up to $206,000,000 and pay low single-digit royalties on sales.<\/p>\n<p>\n        <strong>Conference Call and Webcast Information:<\/strong>\n      <\/p>\n<p align=\"justify\">Corbus management will host a conference call and webcast presentation for investors, analysts, and other interested parties today, Tuesday, June 1, 2021, at 8:30 a.m. ET.<\/p>\n<p align=\"justify\">To participate on the call, please dial (877) 407-3978 (domestic) or (412) 902-0039 (international). The\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=XPYDaMfbQ6dtP4m0h-nwINH-53Am0yJSlcWi4_RKd3yVpWGArLNk3vzj_N4e7qOLSbvW5LX6KMk4QtLiMrpPoTk9fVFdP6LA-YhuZcAJLWdoaykRP7N0wjXqchiG5KLBNLQNue4MB84KP8dvC3U2uppCG7NfYLuq-ylzPiYic25ujIPPlhTr18ZK7Vg_z5Lpzm414Tf_NL9CyJQzOWM35GQhKUKRcAY50JCYWx4EC1q80YfFu2WBdJScvYImk4QG99R-m8hnGZ7riEK_w-iVns_lgErGFQ7KC8fi_tw540T_PPlZZ0bHGRz17WenJn7P-XhGWE1cbebzXM7J0K8aYAzjqMK9rOjJjec4ZaVy_mtFS3jF9aFpoWiHpPRDIIqDQ48STIgMQ7b71M368Hd8PA==\" rel=\"nofollow noopener\" target=\"_blank\">live webcast<\/a> will be accessible on the\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Spm06L61w2FKdB44hbtLPSbZOupwD6H3RrUuaiqI8YLe_93pD0ajsmlZ1LCeniOzvRgncNWhewSV66b3grZWTQ==\" rel=\"nofollow noopener\" target=\"_blank\">Events<\/a>\u00a0page of the\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=x0RvdLU3D-6Nf-yF3_zFoYAwnXgTksNJpXDs8LfSxu3IesgdsRf4RMRZWxFc8hO2GU0TYmeDoCf5-6u1XHRXtA==\" rel=\"nofollow noopener\" target=\"_blank\">Investors<\/a>\u00a0section of the Corbus website,\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=dXiC-H_NdVeFubcnohVLk2VOrrsnzFgodlGF_Le8DASCJKg8hgPWaGVE2SClqGUoeTZPtVoZ9-XIBkgj8YMxpuFktbPfrrb_YOu_nJe-IM0=\" rel=\"nofollow noopener\" target=\"_blank\">www.corbuspharma.com<\/a>, and will be archived for 90 days.<\/p>\n<p>\n        <strong>About UCSF<\/strong>\n      <\/p>\n<p align=\"justify\">The University of California, San Francisco (UCSF) is exclusively focused on the health sciences and is dedicated to promoting health worldwide\u00a0through advanced biomedical research, graduate-level education in the life sciences and health\u00a0professions, and excellence in patient care. It includes UCSF Health, which comprises three top-ranked hospitals, as well as affiliations throughout the Bay Area. Learn more at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=m0iN-Jv1WXDzkjuRxtPpOa9u7Jg-yhAsZWj17uXXi4EY8uYFMr_AQsDiJHPVEGIq33wN3xl-0RJTCo_EQp3Gfg==\" rel=\"nofollow noopener\" target=\"_blank\">ucsf.edu<\/a><em>,\u00a0<\/em>or see our\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=IMxTveF0iyc4IDXpMPsWVJ3T5W5SZBKmsOnJCHZOyM84-Viv_1sQpnOJ5fw-3NRdZ349Q8p-vAJIpd23COvraudsTQein7IeZ1sK4gSR7P3ChLVtGqy21zbSV_dEPgzA3KvqT3lOI7ZgUcxQhOVTSg==\" rel=\"nofollow noopener\" target=\"_blank\">Fact Sheet<\/a><em>.<\/em><\/p>\n<p>\n        <strong>About <\/strong><br \/>\n        <strong>Panorama Research Inc.<\/strong>\n      <\/p>\n<p align=\"justify\">Panorama Research Inc. is a translational research lab and incubator with deep domain expertise in antibody engineering and preclinical drug development. Panorama focuses on identifying promising therapeutic targets and incubates novel, proprietary technologies from in-house research or through collaboration with leading academic institutions. Panorama is headquartered in Sunnyvale, CA.<\/p>\n<p>\n        <strong>About Corbus<\/strong>\n      <\/p>\n<p align=\"justify\">Corbus is committed to leveraging our expertise in immunology to fulfill our purpose of developing innovative new medicines that improve the lives of people living with inflammatory, fibrotic, and metabolic diseases, and cancer. Corbus\u2019 current pipeline includes small molecules that activate or inhibit the endocannabinoid system and anti-integrin monoclonal antibodies that block activation of TGF\u03b2. Corbus is headquartered in Norwood, Massachusetts. For more information on Corbus, visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Xza0NUKaCzHwzh_ECF1bZADPj1-IqMgea26Cxu36MsFQAqHU6-hHsYoitNf5bEYjwq3qaY5KSMKYnBhfF26IFfcNEtzn9fhWpBtpWOQFrEE=\" rel=\"nofollow noopener\" target=\"_blank\">corbuspharma.com<\/a>. Connect with us on\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=sMrApay_36qKU1u3YY56TuFp4L0HFCOaVTEFQHbvT9x-Ozhoq_gEZpmIKO-f-BYORxuIJjFH0WpLaLoOQh7DSw==\" rel=\"nofollow noopener\" target=\"_blank\">Twitter<\/a>,\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TWmSZxIsMn1J2X78NOfS-p78MnmZyk4ec9D4keguAJsQUyzNjK13n7Uhya-AmjX6xrmAkMtwxSebeiRMeNMi2opfCL2WMWLqkO2JFLYEu8mN05a7k1StIaY-lodS1n-x\" rel=\"nofollow noopener\" target=\"_blank\">LinkedIn<\/a> and\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=04iKGneyFzqrQhcqBBAGCXeOfASyx5yAp7Y__oLSpBooWoethJcvMw_QdnLNOAmuR7BTMVkEy_eqm55YmjSRwm_CQiTXfTUOTj0bPHP9grI=\" rel=\"nofollow noopener\" target=\"_blank\">Facebook<\/a>.<\/p>\n<p>\n        <strong>Forward-Looking Statements <\/strong>\n      <\/p>\n<p align=\"justify\">This press release contains certain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and Private Securities Litigation Reform Act, as amended, including those relating to the Company&#8217;s restructuring, trial results, product development, clinical and regulatory timelines, market opportunity, competitive position, possible or assumed future results of operations, business strategies, potential growth opportunities and other statement that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which we operate and management&#8217;s current beliefs and assumptions.<\/p>\n<p align=\"justify\">These statements may be identified by the use of forward-looking expressions, including, but not limited to, &#8220;expect,&#8221; &#8220;anticipate,&#8221; &#8220;intend,&#8221; &#8220;plan,&#8221; &#8220;believe,&#8221; &#8220;estimate,&#8221; &#8220;potential,\u201d &#8220;predict,&#8221; &#8220;project,&#8221; &#8220;should,&#8221; &#8220;would&#8221; and similar expressions and the negatives of those terms. These statements relate to future events or our financial performance and involve known and unknown risks, uncertainties, and other factors, including the potential impact of the recent COVID-19 pandemic and the potential impact of sustained social distancing efforts, on our operations, clinical development plans and timelines, which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include those set forth in the Company&#8217;s filings with the Securities and Exchange Commission. Prospective investors are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <u>UCSF Contact: <\/u><br \/>\n        <\/strong><br \/>\n        <br \/>Ellen Kats, Assistant Director, Business Development &amp; Licensing <br \/>Email: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=0PHXW454517Wn6hazwYUUYO-zuQhsZ7E-9AqFq9drxP_NPBxoMs0mZSwVFbHjTN2s_YAW2uG7rILiEH-MP6-Zn5qKSzt6R3zeI8_1RHqAXk=\" rel=\"nofollow noopener\" target=\"_blank\">ellen.kats@ucsf.edu<\/a><\/p>\n<p>\n        <strong><br \/>\n          <u>Corbus Pharmaceuticals Contacts: <\/u><br \/>\n        <\/strong><br \/>\n        <br \/>Ted Jenkins, Senior Director, Investor Relations and Corporate Communications <br \/>Phone: +1 (617) 415-7745 <br \/>Email: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=LGBJ7XOxT4PDGWfx21GYXWAOwEf4jYaQiZ3QwuKO4VCkjIfGcfi5E44_lvN9nsx6S0H0eFIFie9LjGZVLzwgO938oKhX_pkVkMMH63YLxqw=\" rel=\"nofollow noopener\" target=\"_blank\">ir@corbuspharma.com<\/a><\/p>\n<p>Lindsey Smith, Director, Investor Relations and Corporate Communications <br \/>Phone: +1 (617) 415-7749 <br \/>Email: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=5EbcQB37rjCPLRiWwTQKw3Awkv3NK7SSdRzT69gUTcppqOU83Rg-FDWm0dUCgYHX_arpzqkfddjABZ-b-ko4SAKq1LBZ-aYlmOEEWEF6_3qos9pYcolUWzWtA2R341jz\" rel=\"nofollow noopener\" target=\"_blank\">mediainfo@corbuspharma.com<\/a><\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI0NTMyNSM0MjA4MDM5IzUwMDA0ODIwOQ==\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/3ea25a91-3895-4245-9026-1099815f5484\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Corbus diversifies pipeline with two new mAbs that target integrins that inhibit activation of TGF\u03b2 High potency anti-\ufeff\u03b1\ufeffv\u03b28\u00a0mAb\u00a0licensed from University of California San Francisco\u00a0and anti-\u03b1v\u03b26\/\u03b1v\u03b28 mAb licensed from Panorama Research Inc. Both mAbs expected to start Phase 1 testing in 2022 Capital and resources in place to advance multiple programs into clinical development Company to host conference call and webcast today, Tuesday, June 1, 2021 at 8:30 a.m. ET Norwood, MA, June 01, 2021 (GLOBE NEWSWIRE) &#8212; Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (\u201cCorbus\u201d or the \u201cCompany\u201d), today announced licensing deals for two new monoclonal antibodies (mAbs), CRB-601 and CRB-602, that target integrins to inhibit activation of transforming growth factor \u03b2 (TGF\u03b2). This new integrin program, in addition to the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-499824","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Corbus diversifies pipeline with two new mAbs that target integrins that inhibit activation of TGF\u03b2 High potency anti-\ufeff\u03b1\ufeffv\u03b28\u00a0mAb\u00a0licensed from University of California San Francisco\u00a0and anti-\u03b1v\u03b26\/\u03b1v\u03b28 mAb licensed from Panorama Research Inc. Both mAbs expected to start Phase 1 testing in 2022 Capital and resources in place to advance multiple programs into clinical development Company to host conference call and webcast today, Tuesday, June 1, 2021 at 8:30 a.m. ET Norwood, MA, June 01, 2021 (GLOBE NEWSWIRE) &#8212; Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (\u201cCorbus\u201d or the \u201cCompany\u201d), today announced licensing deals for two new monoclonal antibodies (mAbs), CRB-601 and CRB-602, that target integrins to inhibit activation of transforming growth factor \u03b2 (TGF\u03b2). This new integrin program, in addition to the &hellip; Continue reading &quot;Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-06-01T11:08:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODI0NTMyNSM0MjA4MDM5IzUwMDA0ODIwOQ==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases\",\"datePublished\":\"2021-06-01T11:08:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/\"},\"wordCount\":1206,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODI0NTMyNSM0MjA4MDM5IzUwMDA0ODIwOQ==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/corbus-pharmaceuticals-licenses-two-integrin-targeting-mabs-further-expanding-pipeline-into-cancer-and-fibrotic-diseases\\\/\",\"name\":\"Corbus Pharmaceuticals Licenses Two Integrin Targeting mAbs Further Expanding Pipeline into Cancer and Fibrotic Diseases - 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Both mAbs expected to start Phase 1 testing in 2022 Capital and resources in place to advance multiple programs into clinical development Company to host conference call and webcast today, Tuesday, June 1, 2021 at 8:30 a.m. ET Norwood, MA, June 01, 2021 (GLOBE NEWSWIRE) &#8212; Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) (\u201cCorbus\u201d or the \u201cCompany\u201d), today announced licensing deals for two new monoclonal antibodies (mAbs), CRB-601 and CRB-602, that target integrins to inhibit activation of transforming growth factor \u03b2 (TGF\u03b2). 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