{"id":494789,"date":"2021-05-18T07:04:18","date_gmt":"2021-05-18T11:04:18","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/"},"modified":"2021-05-18T07:04:18","modified_gmt":"2021-05-18T11:04:18","slug":"cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/","title":{"rendered":"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder"},"content":{"rendered":"

<\/p>\n

Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder<\/b><\/p>\n

TORONTO–(BUSINESS WIRE<\/a>)–Cybin<\/a> Inc. (NEO:CYBN) (OTCQB:CLXPF), a biotechnology company focused on progressing psychedelic therapeutics, today announced that the Institutional Review Board (\u201cIRB\u201d) at the University of the West Indies Hospital, in Jamaica has granted approval to commence the study of its sublingual psilocybin formulation (\u201cCYB001\u201d) in a Phase II clinical trial for patients suffering with Major Depressive Disorder (\u201cMDD\u201d). Commencement of the clinical trial is subject to final confirmation of study material specifications by Jamaica\u2019s Ministry of Health.\n<\/p>\n

\nMDD is a disease that affected over 7.1% of the U.S. adult population in 2017 according to the National Institute of Mental Health. Globally, nearly 300 million people suffer from depression according to the World Health Organization.\n<\/p>\n

\nPsilocybin has been granted Breakthrough Therapy Designation by the U.S. Food and Drug Administration to multiple entities in the USA, and this specific trial will become the first of its kind comparing a 25mg psilocybin capsule with Cybin\u2019s proprietary sublingual film formulation.\n<\/p>\n

\nThe clinical trial will consist of a Phase IIa study of 40 patients to identify the bio-equivalent dose of Cybin\u2019s proprietary sublingual psilocybin formulation versus a 25mg oral capsule. Sublingual delivery is designed to enable rapid absorption of molecules into the bloodstream via the mouth, rather than utilizing the gastrointestinal tract. The goal of the trial is to demonstrate the potential benefits of Cybin\u2019s sublingual delivery method which seeks to deliver faster onset of action, shorter treatment duration, and a lower effective dose.\n<\/p>\n

\n“IRB approval for our study protocols is an important step forward to begin testing our proprietary psilocybin formulation delivered via absorption under the tongue in patients with Major Depressive Disorder. We are planning several additional studies to expand our clinical understanding of this potentially ground-breaking therapeutic. Cybin continues to expand on its 4 active drug programs targeting depression, addiction and other psychiatric conditions alongside its growing portfolio of 50+ proprietary psychedelic molecules. This latest IRB approval moves Cybin closer to unlocking the potential of more scalable therapeutics,\u201d stated Doug Drysdale, Chief Executive Officer.\n<\/p>\n

\nUpon successful completion of the Phase IIa study, Cybin plans to study the safety and efficacy of its CYB001 psilocybin drug candidate in a randomized, placebo-controlled Phase IIb study, in 120 patients with MDD. The primary endpoint of this study is expected to be a reduction in the Montgomery-Asberg Depression Rating Scale (\u201cMADRS\u201d) of depression symptoms at 30 days.\n<\/p>\n

\nThe clinical trial will adhere to ICH-GCP (\u201cThe International Conference on Harmonization-Good Clinical Practice\u201d) guidelines, with the aim to utilize clinical data across the world in jurisdictions such as the United States, Canada and Europe.\n<\/p>\n

About Cybin<\/b><\/p>\n

\nCybin is a leading biotechnology company focused on progressing psychedelic therapeutics for mental illness and addiction by utilizing proprietary drug discovery platforms, innovative drug delivery systems, novel formulation approaches and treatment regimens for psychiatric disorders.\n<\/p>\n

Cautionary Notes and Forward-Looking Statements<\/b><\/p>\n

\nCertain statements in this news release related to the Company are forward-looking statements and are prospective in nature. Forward-looking statements are not based on historical facts, but rather on current expectations and projections about future events and are therefore subject to risks and uncertainties which could cause actual results to differ materially from the future results expressed or implied by the forward-looking statements. These statements generally can be identified by the use of forward-looking words such as \u201cmay\u201d, \u201cshould\u201d, \u201ccould\u201d, \u201cintend\u201d, \u201cestimate\u201d, \u201cplan\u201d, \u201canticipate\u201d, \u201cexpect\u201d, \u201cbelieve\u201d or \u201ccontinue\u201d, or the negative thereof or similar variations. Forward-looking statements in this news release may include statements regarding enhanced liquidity, the value of additional capital markets exposure, access to institutional and retail investors, the Company\u2019s new strategic brand messaging campaign, and psychedelic drug development programs to potentially treat mental health disorders. There are numerous risks and uncertainties that could cause actual results and Cybin\u2019s plans and objectives to differ materially from those expressed in the forward-looking information. Actual results and future events could differ materially from those anticipated in such information. These and all subsequent written and oral forward-looking information are based on estimates and opinions of management on the dates they are made and are expressly qualified in their entirety by this notice. Except as required by law, the Company does not intend to update these forward-looking statements.\n<\/p>\n

\nCybin makes no medical, treatment or health benefit claims about Cybin\u2019s proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psychedelic tryptamine, tryptamine derivatives or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by approved research. There is no assurance that the use of psilocybin, psychedelic tryptamine, tryptamine derivatives or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. Cybin has not conducted clinical trials for the use of its proposed products. Any references to quality, consistency, efficacy and safety of potential products do not imply that Cybin verified such in clinical trials or that Cybin will complete such trials. If Cybin cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on Cybin\u2019s performance and operations.\n<\/p>\n

The NEO Exchange has neither approved nor disapproved the contents of this news release and is not responsible for the adequacy and accuracy of the contents herein.<\/i><\/p>\n

\"\"<\/p>\n

View source version on businesswire.com: <\/span>https:\/\/www.businesswire.com\/news\/home\/20210518005402\/en\/<\/a><\/span><\/p>\n

Investor Contacts:
\n<\/b>
Tim Regan\/Scott Eckstein
\n
KCSA Strategic Communications
\n
Cybin@kcsa.com
\n<\/a><\/p>\n

Lisa M. Wilson
\n
In-Site Communications, Inc.
\n
lwilson@insitecony.com
\n<\/a><\/p>\n

Media Contacts<\/b>:
\n
John Kanakis
\n
Cybin Inc.
\n
John@cybin.com<\/a><\/p>\n

KEYWORDS:<\/b> North America Canada<\/p>\n

INDUSTRY KEYWORDS:<\/b> Biotechnology Mental Health Health Pharmaceutical Clinical Trials<\/p>\n

MEDIA:<\/b><\/p>\n\n\n\n\n
Logo<\/b><\/font><\/td>\n<\/tr>\n
\"Logo\"<\/td>\n<\/tr>\n
<\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder TORONTO–(BUSINESS WIRE)–Cybin Inc. (NEO:CYBN) (OTCQB:CLXPF), a biotechnology company focused on progressing psychedelic therapeutics, today announced that the Institutional Review Board (\u201cIRB\u201d) at the University of the West Indies Hospital, in Jamaica has granted approval to commence the study of its sublingual psilocybin formulation (\u201cCYB001\u201d) in a Phase II clinical trial for patients suffering with Major Depressive Disorder (\u201cMDD\u201d). Commencement of the clinical trial is subject to final confirmation of study material specifications by Jamaica\u2019s Ministry of Health. MDD is a disease that affected over 7.1% of the U.S. adult population in 2017 according to the National Institute of Mental … <\/p>\n

Continue reading “Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-494789","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nCybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder TORONTO–(BUSINESS WIRE)–Cybin Inc. (NEO:CYBN) (OTCQB:CLXPF), a biotechnology company focused on progressing psychedelic therapeutics, today announced that the Institutional Review Board (\u201cIRB\u201d) at the University of the West Indies Hospital, in Jamaica has granted approval to commence the study of its sublingual psilocybin formulation (\u201cCYB001\u201d) in a Phase II clinical trial for patients suffering with Major Depressive Disorder (\u201cMDD\u201d). Commencement of the clinical trial is subject to final confirmation of study material specifications by Jamaica\u2019s Ministry of Health. MDD is a disease that affected over 7.1% of the U.S. adult population in 2017 according to the National Institute of Mental … Continue reading "Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-05-18T11:04:18+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20210518005402r1&sid=flmnd&distro=nx&lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"5 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder\",\"datePublished\":\"2021-05-18T11:04:18+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/\"},\"wordCount\":986,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&sty=20210518005402r1&sid=flmnd&distro=nx&lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\\\/\",\"name\":\"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder - 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(NEO:CYBN) (OTCQB:CLXPF), a biotechnology company focused on progressing psychedelic therapeutics, today announced that the Institutional Review Board (\u201cIRB\u201d) at the University of the West Indies Hospital, in Jamaica has granted approval to commence the study of its sublingual psilocybin formulation (\u201cCYB001\u201d) in a Phase II clinical trial for patients suffering with Major Depressive Disorder (\u201cMDD\u201d). Commencement of the clinical trial is subject to final confirmation of study material specifications by Jamaica\u2019s Ministry of Health. MDD is a disease that affected over 7.1% of the U.S. adult population in 2017 according to the National Institute of Mental … Continue reading \"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/","og_site_name":"Market Newsdesk","article_published_time":"2021-05-18T11:04:18+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20210518005402r1&sid=flmnd&distro=nx&lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"5 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder","datePublished":"2021-05-18T11:04:18+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/"},"wordCount":986,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&sty=20210518005402r1&sid=flmnd&distro=nx&lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/cybin-granted-irb-approval-for-phase-ii-clinical-trials-of-its-sublingual-psilocybin-formulation-for-the-treatment-of-major-depressive-disorder\/","name":"Cybin Granted IRB Approval for Phase II Clinical Trials of its Sublingual Psilocybin Formulation for the Treatment of Major Depressive Disorder - 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