{"id":476053,"date":"2021-04-14T08:03:32","date_gmt":"2021-04-14T12:03:32","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/protokinetix-engages-multi-national-partner-for-formulation-of-topical-drug-to-treat-dry-eye-disease-ocular-inflammation-with-aagp\/"},"modified":"2021-04-14T08:03:32","modified_gmt":"2021-04-14T12:03:32","slug":"protokinetix-engages-multi-national-partner-for-formulation-of-topical-drug-to-treat-dry-eye-disease-ocular-inflammation-with-aagp","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/protokinetix-engages-multi-national-partner-for-formulation-of-topical-drug-to-treat-dry-eye-disease-ocular-inflammation-with-aagp\/","title":{"rendered":"ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwlistdecimal { list-style-type: decimal }\n.bwuline { text-decoration: underline }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae<\/b><\/p>\n<p>MARIETTA, Ohio&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nProtoKinetix, Incorporated (the &#8220;Company&#8221; or &#8220;ProtoKinetix&#8221;) (OTCQB: <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.otcmarkets.com%2Fstock%2FPKTX%2Fquote&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=PKTX&amp;index=1&amp;md5=36d0d3a6224bf741adddd93a1363782b\">PKTX<\/a>), a clinical-stage biomedical company, today announced that it has engaged a global pharmaceutical company to develop the formulation as a topical ocular drug for the treatment of dry eye disease (DED) and ocular inflammation using AAGP\u00ae.\n<\/p>\n<p>\nFor the development of this drug for DED to date the company has completed:\n<\/p>\n<ol class=\"bwlistdecimal\">\n<li>\nOcular irritation studies\n<\/li>\n<li>\nProof of concept pre-clinical DED trials for efficacy\n<\/li>\n<li>\nConfirmatory pre-clinical DED trials for efficacy\n<\/li>\n<li>\nPilot drug stability (ie. shelf-life) testing\n<\/li>\n<li>\nPilot tolerability and toxicology studies\n<\/li>\n<\/ol>\n<p>\nAll these studies were conducted by market-leading contract research organizations (CRO).\n<\/p>\n<p>\nIn order to progress to clinical trials, the Company intends to complete the following activities:\n<\/p>\n<ol class=\"bwlistdecimal\">\n<li>\nComplete topical application formulation(s)\n<\/li>\n<li>\nConfirmatory DED efficacy tests\n<\/li>\n<li>\nDrug product Good Lab Practice (GLP) IND-enabling safety toxicology\n<\/li>\n<li>\nCommunicate with Federal Drug Administration (FDA) on clinical trial design criteria\n<\/li>\n<\/ol>\n<p><strong>Dry Eye Disease Market Overview<\/strong><\/p>\n<p>\nAccording to <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.reportlinker.com%2Fp05790925%2FDry-Eye-Disease-Market-Growth-Trends-and-Forecast.html%3Futm_source%3DPRN&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=market+research+published+by+Mordor+Intelligence+LLP&amp;index=2&amp;md5=993e9b315165e03e2c498b35f1792fc9\">market research published by Mordor Intelligence LLP<\/a>, studies of the Dry Eye Disease market indicated a value of approximately USD 4.5 billion in 2018, and the market is expected to reach up to USD 6.2 billion by 2024, with an anticipated CAGR of 5.23%, during the forecast period (2019-2024). The growth of dry eye related diseases may include several factors, such as aging, a decrease in the supportive hormones (ex. menopause), systemic inflammatory diseases, ocular surfaces diseases or surgeries affecting the cholinergic nerves, which stimulate tear secretion.\n<\/p>\n<p><b><i>\u201cThis is a critical milestone in our application development and moves us forward to commercialization of ProtoKinetix\u2019s Dry Eye Disease program.\u201d<\/i><\/b> \u2013 Clarence Smith, CEO President\n<\/p>\n<p><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.protokinetix.com%2Fresearch%2F&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=See+the+promising+research+of+AAGP%26%23174%3B+and+results+to+date&amp;index=3&amp;md5=0307dd2bd973cab5c959467a1ee4affc\">See the promising research of AAGP\u00ae and results to date<\/a><\/p>\n<p>\nVisit our new website at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.protokinetix.com%2F&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=ProtoKinetix.com&amp;index=4&amp;md5=ce42709952bff423b0fa6f34403536df\">ProtoKinetix.com<\/a> for more information and to join our email list.\n<\/p>\n<p><span class=\"bwuline\"><b><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.protokinetix.com%2Fabout%2F&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=About+ProtoKinetix%2C+Incorporated&amp;index=5&amp;md5=37fbc2e9e77975381e3ba59d11f5e14e\">About ProtoKinetix, Incorporated<\/a><\/b><\/span><\/p>\n<p class=\"bwalignc\"><b>Cautionary Note Regarding Forward-Looking Statements<\/b><\/p>\n<p><i>The information discussed in this press release includes \u201cforward looking statements\u201d within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. All statements, other than statements of historical facts, included herein concerning, among other things, planned capital expenditures, future cash flows and borrowings, pursuit of potential acquisition opportunities, our financial position, business strategy and other plans and objectives for future operations, are forward looking statements. Although we believe that the expectations reflected in these forward-looking statements are reasonable, they do involve certain assumptions, risks and uncertainties and are not (and should not be considered to be) guarantees of future performance. Refer to our risk factors set forth in our reports filed on Edgar. ProtoKinetix disclaims any obligation to update any forward-looking statement made here.<\/i><\/p>\n<p><i>This press release does not constitute or form a part of any offer or solicitation to purchase or subscribe for securities in the United States.<\/i><\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20210414005060r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20210414005060\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20210414005060\/en\/<\/a><\/span><\/p>\n<p><b>Clarence E. Smith<br \/>\n<\/b><br \/><i>President and Chief Executive Officer<br \/>\n<\/i><br \/>Telephone: 740-434-5041<br \/>\n<br \/>Email: <a rel=\"nofollow\" href=\"mailto:csmith@protokinetix.com\">csmith@protokinetix.com<br \/>\n<\/a><br \/><a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Fwww.linkedin.com%2Fin%2Fclarence-smith-24932a74%2F&amp;esheet=52411168&amp;newsitemid=20210414005060&amp;lan=en-US&amp;anchor=LinkedIn&amp;index=6&amp;md5=d1b158a1795d8538f66f91ee42ccb31e\">LinkedIn<br \/>\n<\/a><br \/>Twitter: @ProtoKinetix\n<\/p>\n<p><b>KEYWORDS:<\/b> United States North America Ohio<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Health Stem Cells Clinical Trials Pharmaceutical Optical Biotechnology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\" \/>\n","protected":false},"excerpt":{"rendered":"<p>ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae MARIETTA, Ohio&#8211;(BUSINESS WIRE)&#8211; ProtoKinetix, Incorporated (the &#8220;Company&#8221; or &#8220;ProtoKinetix&#8221;) (OTCQB: PKTX), a clinical-stage biomedical company, today announced that it has engaged a global pharmaceutical company to develop the formulation as a topical ocular drug for the treatment of dry eye disease (DED) and ocular inflammation using AAGP\u00ae. For the development of this drug for DED to date the company has completed: Ocular irritation studies Proof of concept pre-clinical DED trials for efficacy Confirmatory pre-clinical DED trials for efficacy Pilot drug stability (ie. shelf-life) testing Pilot tolerability and toxicology studies All these studies were conducted by market-leading contract research organizations (CRO). In &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/protokinetix-engages-multi-national-partner-for-formulation-of-topical-drug-to-treat-dry-eye-disease-ocular-inflammation-with-aagp\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-476053","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/protokinetix-engages-multi-national-partner-for-formulation-of-topical-drug-to-treat-dry-eye-disease-ocular-inflammation-with-aagp\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"ProtoKinetix Engages Multi-National Partner for Formulation of Topical Drug to Treat Dry Eye Disease &amp; Ocular Inflammation with AAGP\u00ae MARIETTA, Ohio&#8211;(BUSINESS WIRE)&#8211; ProtoKinetix, Incorporated (the &#8220;Company&#8221; or &#8220;ProtoKinetix&#8221;) (OTCQB: PKTX), a clinical-stage biomedical company, today announced that it has engaged a global pharmaceutical company to develop the formulation as a topical ocular drug for the treatment of dry eye disease (DED) and ocular inflammation using AAGP\u00ae. For the development of this drug for DED to date the company has completed: Ocular irritation studies Proof of concept pre-clinical DED trials for efficacy Confirmatory pre-clinical DED trials for efficacy Pilot drug stability (ie. shelf-life) testing Pilot tolerability and toxicology studies All these studies were conducted by market-leading contract research organizations (CRO). 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For the development of this drug for DED to date the company has completed: Ocular irritation studies Proof of concept pre-clinical DED trials for efficacy Confirmatory pre-clinical DED trials for efficacy Pilot drug stability (ie. shelf-life) testing Pilot tolerability and toxicology studies All these studies were conducted by market-leading contract research organizations (CRO). 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