{"id":471452,"date":"2021-04-06T07:30:50","date_gmt":"2021-04-06T11:30:50","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=471452"},"modified":"2021-04-06T07:30:50","modified_gmt":"2021-04-06T11:30:50","slug":"gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\/","title":{"rendered":"Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma"},"content":{"rendered":"
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PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n BEIJING<\/span> and BRIDGEWATER, N.J.<\/span>, April 6, 2021<\/span> \/PRNewswire\/ —\u00a0Gan & Lee Pharmaceuticals Co., Ltd. (hereinafter referred to as Gan & Lee, stock code: 603087.SH), a global biopharmaceutical company, today announced that the European Medicine Agency (EMA) Committee for Orphan Medicinal Products granted orphan drug designation for the investigational compound GLR2007, for the treatment of glioma. <\/p>\n

Glioma is a broad term describing neuroepithelial tumors originating from glial cells of the central nervous system, including astrocytic tumors such as glioblastomas (GBM). GBM is one of the most aggressive primary brain tumors and has median survival of 12 to 15 months, despite advances in surgery, chemotherapy, and radiation therapy1<\/sup>.\u00a0 Gan & Lee’s current clinical development program for GLR2007, a cyclin-dependent kinase 4\/6 (CDK 4\/6) inhibitor, is investigating the treatment of advanced solid tumors which has the potential to provide physicians and patients with a much-needed treatment option.<\/p>\n

“The EMA’s positive decision for GLR2007’s orphan drug designation is another milestone in the clinical development program as this compound was also recently granted ODD by the FDA,” Dr. Michelle Mazuranic<\/span>, Head of Global Medical Affairs, Gan & Lee.\u00a0 The granting of an orphan designation request does not alter the standard regulatory requirements and process for obtaining market approval. <\/p>\n

Orphan drug designation in the\u00a0European Union\u00a0(EU) is granted by the\u00a0European Commission\u00a0based on a positive opinion issued by the\u00a0EMA Committee for Orphan Medicinal Products. To qualify, an investigational medicine must be intended to treat a seriously debilitating or life-threatening condition that affects fewer than five in 10,000 people in the EU, and there must be sufficient non-clinical or clinical data to suggest the investigational medicine may produce clinically relevant outcomes and the potential for significant benefit over currently approved products. The EMA orphan drug designation can provide companies with clinical protocol assistance, differentiated evaluation procedures for Health Technology Assessments in certain countries, access to a centralized marketing authorization procedure valid in all EU member states, and reduced regulatory fees. After being granted marketing approval, compounds with orphan designation are eligible for 10 years of market exclusivity. <\/p>\n

\n About Gan & Lee <\/b>\n <\/p>\n

Gan & Lee successfully developed the first Chinese domestic biosynthetic human insulin. The company has five recombinant insulin analogs commercialized in China<\/span> including long-acting glargine injection (Basalin\u00ae), fast-acting lispro injection (Prandilin\u00ae), fast-acting aspart injection (Rapilin\u2122), mixed protamine zinc lispro injection (25R) (Prandilin\u00ae25), aspart 30 injection (Rapilin\u212230), reusable insulin injection pen (GanleePen\u2122), and disposable pen needle (Ganlee Fine\u2122).<\/p>\n

In the future, Gan & Lee strives to achieve a comprehensive coverage in the field of diabetes diagnosis and treatment. Moving forward to advance Gan & Lee’s goal of becoming a world-class pharmaceutical company, we will also take an active part in developing new chemical entities to treat various forms of cardiovascular diseases, metabolic diseases, cancer, and other therapeutics. For more information, please contact investorrelations@ganlee.us<\/a>. <\/p>\n

\n References<\/b>\n <\/p>\n

1. Galanis E, et. al. https:\/\/doi.org\/10.1200\/JCO.2005.23.622<\/a><\/p>\n

\n Contact<\/b>: Gina Antonucci<\/span>, #: 888-288-5395, investorrelations@ganlee.us<\/a><\/p>\n

\u00a0<\/p>\n

\u00a0<\/p>\n

\n \"Cision\" View original content:http:\/\/www.prnewswire.com\/news-releases\/gan–lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma-301262904.html<\/a><\/p>\n

SOURCE Gan & Lee Pharmaceuticals Co., Ltd.<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

PR Newswire BEIJING and BRIDGEWATER, N.J., April 6, 2021 \/PRNewswire\/ —\u00a0Gan & Lee Pharmaceuticals Co., Ltd. (hereinafter referred to as Gan & Lee, stock code: 603087.SH), a global biopharmaceutical company, today announced that the European Medicine Agency (EMA) Committee for Orphan Medicinal Products granted orphan drug designation for the investigational compound GLR2007, for the treatment of glioma. Glioma is a broad term describing neuroepithelial tumors originating from glial cells of the central nervous system, including astrocytic tumors such as glioblastomas (GBM). GBM is one of the most aggressive primary brain tumors and has median survival of 12 to 15 months, despite advances in surgery, chemotherapy, and radiation therapy1.\u00a0 Gan & Lee’s current clinical development program for GLR2007, a cyclin-dependent kinase … <\/p>\n

Continue reading “Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-471452","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nGan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire BEIJING and BRIDGEWATER, N.J., April 6, 2021 \/PRNewswire\/ —\u00a0Gan & Lee Pharmaceuticals Co., Ltd. (hereinafter referred to as Gan & Lee, stock code: 603087.SH), a global biopharmaceutical company, today announced that the European Medicine Agency (EMA) Committee for Orphan Medicinal Products granted orphan drug designation for the investigational compound GLR2007, for the treatment of glioma. Glioma is a broad term describing neuroepithelial tumors originating from glial cells of the central nervous system, including astrocytic tumors such as glioblastomas (GBM). GBM is one of the most aggressive primary brain tumors and has median survival of 12 to 15 months, despite advances in surgery, chemotherapy, and radiation therapy1.\u00a0 Gan & Lee’s current clinical development program for GLR2007, a cyclin-dependent kinase … Continue reading "Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-06T11:30:50+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/c212.net\/c\/img\/favicon.png?sn=LN33244&sd=2021-04-06\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma\",\"datePublished\":\"2021-04-06T11:30:50+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/\"},\"wordCount\":521,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/c212.net\\\/c\\\/img\\\/favicon.png?sn=LN33244&sd=2021-04-06\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/gan-lee-receives-ema-orphan-drug-designation-for-phase-i-drug-candidate-glr2007-for-the-treatment-of-glioma\\\/\",\"name\":\"Gan & Lee receives EMA orphan drug designation for Phase I drug candidate GLR2007 for the treatment of glioma - 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