{"id":469565,"date":"2021-04-01T08:03:32","date_gmt":"2021-04-01T12:03:32","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=469565"},"modified":"2021-04-01T08:03:32","modified_gmt":"2021-04-01T12:03:32","slug":"egenesis-expands-research-collaboration-with-leading-academic-medical-center","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/","title":{"rendered":"eGenesis Expands Research Collaboration with Leading Academic Medical Center"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"center\">\n        <em>Collaboration will now include<\/em> in vivo<em> testing of lead kidney xenotransplant program in addition to pancreatic islet xenotransplant program<\/em><\/p>\n<p>CAMBRIDGE, Mass., April  01, 2021  (GLOBE NEWSWIRE) &#8212; eGenesis, a gene-editing and genome-engineering company developing human-compatible organs, tissues, and cells, today announced the expansion of a research collaboration with Duke University School of Medicine. The expanded collaboration now includes preclinical research of gene-edited kidneys implanted in non-human primate (NHP) recipients, which builds on the original research collaboration for the implantation of the Company\u2019s gene-edited pancreatic islet cells in NHPs that began in 2020. This collaboration is in addition to eGenesis\u2019 successful partnership evaluating gene edited kidneys and other organs in NHPs with Massachusetts General Hospital, which was initiated in 2017.\u00a0<\/p>\n<p>Dr. Stuart Knechtle, M.D., William R. Kenan, Jr. Professor of Surgery in the School of Medicine, and Executive Director of the Duke Transplant Center, will lead the research.<\/p>\n<p>\u201cOrgan transplantation extends the lifespan and improves the quality of life for patients suffering from organ failure,\u201d said Dr. Knechtle. \u201cSince the advent of successful transplants, there has been a shortage of transplantable organs, resulting in unnecessary patient suffering and death. Xenotransplantation could potentially ease the organ shortage crisis by providing immediate access to transplantable organs for patients in need.\u201d<\/p>\n<p>Michael Curtis, Ph.D., President of Research &amp; Development of eGenesis added, \u201cThe Duke Medical team under Dr. Knechtle\u2019s leadership is a leading transplant program with strong research capabilities in preventing organ rejection. This collaboration will accelerate research and validation of our gene edited kidneys, leading to their evaluation in clinical trials. We look forward to working with our colleagues at Duke and to advancing the field of transplantation.\u201d<\/p>\n<p>\n        <strong>About Transplantation and Xenotransplantation<\/strong><br \/>\n        <br \/>The demand for lifesaving organs far outnumbers available supply. In the U.S. today, 20 people die every day due to lack of available organs for transplant and every 10 minutes an additional name is added to the national transplant waitlist. There are more than 110,000 people in need of an organ transplant in the U.S. alone.<\/p>\n<p>The concept of xenotransplantation, or the transplantation of organs, tissue and cells from one species to another, has been explored for several decades, with the pig considered the most suitable donor for humans. However, until the development of modern gene editing tools, hurdles related to virology and immunology have prevented porcine organ xenotransplantation from advancing beyond early preclinical research.<\/p>\n<p>\n        <strong>About eGenesis<\/strong><br \/>\n        <br \/>eGenesis\u2019s goal is to transform the field of transplantation by offering safe and effective organs, tissues, and cells to patients in need. The company harnesses gene editing technology including CRISPR, to address the key issues that have impeded xenotransplantation to date. eGenesis\u2019s development pipeline includes lead programs for kidney and islet cell transplant as well as earlier-stage programs focused on other solid organs. Learn more at egenesisbio.com.<\/p>\n<p>\n        <strong>Contacts:<\/strong><br \/>\n        <br \/>\n        <strong>Investors<\/strong><br \/>\n        <br \/>John Grimaldi<br \/>Burns McClellan, Inc.<br \/>212-213-0006<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=bOli-_f-mtJc6pIeuVdPbLNIbSxGS5P2QDSuXCQhXL7sZDHuW6xb-kRSxJJv-rAOXwMpMqa9f2VPYA2reEbcwIfnWcqiXAkxoMBuX4g1Hig=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">jgrimaldi@burnsmc.com<\/a><\/p>\n<p>\n        <strong>Media<\/strong><br \/>\n        <br \/>Ryo Imai \/ Robert Flamm, Ph.D.<br \/>Burns McClellan, Inc.<br \/>212-213-0006 ext. 315 \/ 364<br \/><u><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=gSnoQQUlb8z_815uOb2jDsyBldeK1vHEAtnPmU1aK2nIAcdbi1AqCdqjB_8FrExN-YPCSGZNuX07i0wiRJ-mdA==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">Rimai@burnsmc.com<\/a><\/u>\u00a0\/\u00a0<u><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=W3cUwmbj-zb4mnj4v8Tzy9ZHsLbgFTO6a0CgzmAgnsCI0WFB7On7NXlYkUMOYUvhL4pdGMVOdRmRtSLys3C7SBmm0KMMXbiGVfDQfFAzP5M=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">rflamm@burnsmc.com<\/a><\/u><\/p>\n<p>\u00a0<\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODIwOTQ4NCM0MDk4ODUxIzIxODgzMjg=\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/e8ff69ae-42df-4bce-aed4-0b0b4b307ddf\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Collaboration will now include in vivo testing of lead kidney xenotransplant program in addition to pancreatic islet xenotransplant program CAMBRIDGE, Mass., April 01, 2021 (GLOBE NEWSWIRE) &#8212; eGenesis, a gene-editing and genome-engineering company developing human-compatible organs, tissues, and cells, today announced the expansion of a research collaboration with Duke University School of Medicine. The expanded collaboration now includes preclinical research of gene-edited kidneys implanted in non-human primate (NHP) recipients, which builds on the original research collaboration for the implantation of the Company\u2019s gene-edited pancreatic islet cells in NHPs that began in 2020. This collaboration is in addition to eGenesis\u2019 successful partnership evaluating gene edited kidneys and other organs in NHPs with Massachusetts General Hospital, which was initiated in 2017.\u00a0 Dr. &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;eGenesis Expands Research Collaboration with Leading Academic Medical Center&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-469565","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>eGenesis Expands Research Collaboration with Leading Academic Medical Center - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"eGenesis Expands Research Collaboration with Leading Academic Medical Center - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Collaboration will now include in vivo testing of lead kidney xenotransplant program in addition to pancreatic islet xenotransplant program CAMBRIDGE, Mass., April 01, 2021 (GLOBE NEWSWIRE) &#8212; eGenesis, a gene-editing and genome-engineering company developing human-compatible organs, tissues, and cells, today announced the expansion of a research collaboration with Duke University School of Medicine. The expanded collaboration now includes preclinical research of gene-edited kidneys implanted in non-human primate (NHP) recipients, which builds on the original research collaboration for the implantation of the Company\u2019s gene-edited pancreatic islet cells in NHPs that began in 2020. This collaboration is in addition to eGenesis\u2019 successful partnership evaluating gene edited kidneys and other organs in NHPs with Massachusetts General Hospital, which was initiated in 2017.\u00a0 Dr. &hellip; Continue reading &quot;eGenesis Expands Research Collaboration with Leading Academic Medical Center&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-04-01T12:03:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODIwOTQ4NCM0MDk4ODUxIzIxODgzMjg=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"eGenesis Expands Research Collaboration with Leading Academic Medical Center\",\"datePublished\":\"2021-04-01T12:03:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/\"},\"wordCount\":504,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODIwOTQ4NCM0MDk4ODUxIzIxODgzMjg=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\\\/\",\"name\":\"eGenesis Expands Research Collaboration with Leading Academic Medical Center - 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The expanded collaboration now includes preclinical research of gene-edited kidneys implanted in non-human primate (NHP) recipients, which builds on the original research collaboration for the implantation of the Company\u2019s gene-edited pancreatic islet cells in NHPs that began in 2020. This collaboration is in addition to eGenesis\u2019 successful partnership evaluating gene edited kidneys and other organs in NHPs with Massachusetts General Hospital, which was initiated in 2017.\u00a0 Dr. &hellip; Continue reading \"eGenesis Expands Research Collaboration with Leading Academic Medical Center\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/","og_site_name":"Market Newsdesk","article_published_time":"2021-04-01T12:03:32+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODIwOTQ4NCM0MDk4ODUxIzIxODgzMjg=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"eGenesis Expands Research Collaboration with Leading Academic Medical Center","datePublished":"2021-04-01T12:03:32+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/"},"wordCount":504,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODIwOTQ4NCM0MDk4ODUxIzIxODgzMjg=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/egenesis-expands-research-collaboration-with-leading-academic-medical-center\/","name":"eGenesis Expands Research Collaboration with Leading Academic Medical Center - 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