{"id":460830,"date":"2021-03-18T10:20:27","date_gmt":"2021-03-18T14:20:27","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=460830"},"modified":"2021-03-18T10:20:27","modified_gmt":"2021-03-18T14:20:27","slug":"anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/","title":{"rendered":"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">BERNARDSVILLE, N.J., March  18, 2021  (GLOBE NEWSWIRE) &#8212; Anima Biotech, the leader in the discovery of small molecule drugs that selectively control mRNA translation, today announced that the company has entered into a strategic collaboration with Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d) to discover and develop a new class of medicines for genetically-defined neurological diseases.<\/p>\n<p>Under the terms of the agreement, Anima will use its Translation Control Therapeutics platform to discover novel mRNA translation modulators against the collaboration targets. The parties will collaborate to advance the molecules to clinical candidates, which Takeda has the exclusive rights to develop and commercialize.<\/p>\n<p>The preclinical research collaboration will initially include Anima\u2019s early Huntington\u2019s Disease program against the HTT target, selectively inhibiting the mutated protein with small molecules and two additional targets named by Takeda, related to neurological diseases. Takeda will pay Anima up to approximately $120 million in upfront and preclinical research milestone payments and up to $1.1 billion in clinical and commercial milestones, assuming success of the three programs. Anima is also eligible to receive tiered royalties on net sales of each product resulting from the collaboration. Takeda has a time limited option to expand the collaboration with up to three additional targets subject to additional payments to Anima of up to $1.2 billion and tiered royalties, assuming success of these programs.<\/p>\n<p>\u201cAnima Biotech\u2019s expertise in understanding the complex regulatory mechanisms of protein expression in the central nervous system makes them an ideal partner to explore this novel area of drug discovery,\u201d said Ceri Davies, Head, Neuroscience Drug Discovery Unit at Takeda. \u201cBy combining Anima\u2019s platform with our strength in translational medicine and clinical development, we aim to develop medicines that deliver greater benefits to patients with genetically-defined neurological diseases where there are non-existent or ineffective treatment options.\u201d<\/p>\n<p>\u201cPartnering is a core strategy of Anima and our model is to build collaborations that maximize the probability of success by combining our discovery platform and expertise in translation control biology with the scientific, clinical and commercial capabilities of our partners,\u201d said Yochi Slonim, Anima\u2019s co-founder &amp; CEO. \u201cTakeda\u2018s leadership and depth of scientific expertise in the CNS area is ideally suited for our second Pharma partnership in Neuroscience and further validates our leadership in mRNA translation control. We are looking forward to working together with Takeda in a true collaboration model.\u201d<\/p>\n<p>\n        <strong>About Anima Biotech<\/strong><\/p>\n<p>Anima Biotech is pioneering Translation Control Therapeutics, a novel approach for the discovery of small molecules that selectively control mRNA translation as a new strategy against undruggable proteins. With our proprietary technology that emits light pulses from ribosomes, we identify drug candidates that selectively decrease or increase the translation of proteins and elucidate their mechanism of action in a new target space. Our pipeline includes programs in Fibrosis (tissue selective Collagen I translation inhibitors), Oncology (c-Myc translation inhibitors and K-Ras translation inhibitors), RSV (viral translation inhibitors) and Repeat Associated Diseases (translation malfunctions in multiple neurological diseases). In addition to our pipeline, we have established partnerships for the discovery and development of mRNA translation modulators in Neuroscience, including our strategic partnerships with Lilly and Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d). Our science was further validated with seven patents, 15 peer reviewed publications and 17 scientific collaborations. To learn more about us, visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=cQ96Tx866_tICxJxWnDqaTRq6Nq1TMU9smx2wVs3zE9yLrW6s6f-N48yM71M0cv2GfZOgoDYi6A99Mu-0A1abNNHsuFjcBocVcCYlXLgZ7o=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">https:\/\/www.animabiotech.com<\/a>.<\/p>\n<p>\n        <strong>Media Contact:<\/strong><br \/>\n        <br \/>Andrew Mielach <br \/>LifeSci Communications<br \/>+1.646.876.5868<br \/>amielach@lifescicomms.com<\/p>\n<p \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE5MTk1MSM0MDY5MzQ0IzUwMDA1MjgzMQ==\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/9d65633b-e8e5-4f66-bd9b-515297b4b5b9\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>BERNARDSVILLE, N.J., March 18, 2021 (GLOBE NEWSWIRE) &#8212; Anima Biotech, the leader in the discovery of small molecule drugs that selectively control mRNA translation, today announced that the company has entered into a strategic collaboration with Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d) to discover and develop a new class of medicines for genetically-defined neurological diseases. Under the terms of the agreement, Anima will use its Translation Control Therapeutics platform to discover novel mRNA translation modulators against the collaboration targets. The parties will collaborate to advance the molecules to clinical candidates, which Takeda has the exclusive rights to develop and commercialize. The preclinical research collaboration will initially include Anima\u2019s early Huntington\u2019s Disease program against the HTT target, selectively inhibiting the mutated protein &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-460830","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"BERNARDSVILLE, N.J., March 18, 2021 (GLOBE NEWSWIRE) &#8212; Anima Biotech, the leader in the discovery of small molecule drugs that selectively control mRNA translation, today announced that the company has entered into a strategic collaboration with Takeda Pharmaceutical Company Limited (\u201cTakeda\u201d) to discover and develop a new class of medicines for genetically-defined neurological diseases. Under the terms of the agreement, Anima will use its Translation Control Therapeutics platform to discover novel mRNA translation modulators against the collaboration targets. The parties will collaborate to advance the molecules to clinical candidates, which Takeda has the exclusive rights to develop and commercialize. The preclinical research collaboration will initially include Anima\u2019s early Huntington\u2019s Disease program against the HTT target, selectively inhibiting the mutated protein &hellip; Continue reading &quot;Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-18T14:20:27+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE5MTk1MSM0MDY5MzQ0IzUwMDA1MjgzMQ==\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases\",\"datePublished\":\"2021-03-18T14:20:27+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/\"},\"wordCount\":570,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE5MTk1MSM0MDY5MzQ0IzUwMDA1MjgzMQ==\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\\\/\",\"name\":\"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases - 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Under the terms of the agreement, Anima will use its Translation Control Therapeutics platform to discover novel mRNA translation modulators against the collaboration targets. The parties will collaborate to advance the molecules to clinical candidates, which Takeda has the exclusive rights to develop and commercialize. The preclinical research collaboration will initially include Anima\u2019s early Huntington\u2019s Disease program against the HTT target, selectively inhibiting the mutated protein &hellip; Continue reading \"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/","og_site_name":"Market Newsdesk","article_published_time":"2021-03-18T14:20:27+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE5MTk1MSM0MDY5MzQ0IzUwMDA1MjgzMQ==","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases","datePublished":"2021-03-18T14:20:27+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/"},"wordCount":570,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE5MTk1MSM0MDY5MzQ0IzUwMDA1MjgzMQ==","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/anima-biotech-announces-strategic-collaboration-with-takeda-to-discover-and-develop-mrna-translation-modulators-for-neurological-diseases\/","name":"Anima Biotech Announces Strategic Collaboration with Takeda\u00a0to Discover and Develop mRNA Translation Modulators\u00a0for Neurological Diseases - 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