{"id":455358,"date":"2021-03-10T17:30:17","date_gmt":"2021-03-10T22:30:17","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=455358"},"modified":"2021-03-10T17:30:17","modified_gmt":"2021-03-10T22:30:17","slug":"zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/","title":{"rendered":"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021"},"content":{"rendered":"<p>        <!--.bwalignc { text-align: center; list-style-position: inside }\n.bwmarginl1 { margin-left: 30px }\n.bwuline { text-decoration: underline }body {font:normal small Arial,Helvetica,sans-serif;color:#000;background-color:#fff;padding:24px;margin:0;} a img {border:0;} h3 {font-size:medium;color:#000;margin:0 0 1em 0; text-align:center;}-->  <\/p>\n<p class=\"bwalignc\"><b>Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021<\/b><\/p>\n<p>VANCOUVER, British Columbia&#8211;(<a href=\"http:\/\/www.businesswire.com\">BUSINESS WIRE<\/a>)&#8211;<br \/>\nZymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today announced the acceptance of five abstracts for poster presentation at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2021 taking place virtually from April 10 \u2013 15, 2021.\n<\/p>\n<p>\nThe poster presentations will be available on Saturday, April 10 at 8:30 am ET on the conference website as well as the Zymeworks website.\n<\/p>\n<p><b>Presentation Details<\/b><\/p>\n<p class=\"bwmarginl1\">\nTitle: <i>PROTECT\u2122, a novel antibody platform for integrating tumor-specific immune modulation and enhancing the therapeutic window of targeted multispecific biologics<br \/>\n<span class=\"bwuline\"><br \/><\/span><\/i>Abstract: 924<br \/>\n<br \/>Session Category: Experimental and Molecular Therapeutics<br \/>\n<br \/>Session Title: Antibody Technologies\n<\/p>\n<p class=\"bwmarginl1\">\nTitle: <i>Increasing the therapeutic index of IL-12 by engineering for tumor-specific protease activation<br \/>\n<span class=\"bwuline\"><br \/><\/span><\/i>Abstract: 1788<br \/>\n<br \/>Session Category: Immunology<br \/>\n<br \/>Session Title: Modifiers of the Tumor Microenvironment\n<\/p>\n<p class=\"bwmarginl1\">\nTitle: <i>Understanding the geometry and valency of bispecific antibodies in the optimization of tumor-dependent activation of 4-1BB<br \/>\n<span class=\"bwuline\"><br \/><\/span><\/i>Abstract: 1737<br \/>\n<br \/>Session Category: Immunology<br \/>\n<br \/>Session Title: Immunomodulatory Agents and Interventions\n<\/p>\n<p class=\"bwmarginl1\">\nTitle: <i>Super-resolution imaging studies of zanidatamab: providing insights into its bispecific mode of action<br \/>\n<span class=\"bwuline\"><br \/><\/span><\/i>Abstract: 1032<br \/>\n<br \/>Session Category: Experimental and Molecular Therapeutics<br \/>\n<br \/>Session Title: Cellular Responses to Anticancer Drugs\n<\/p>\n<p class=\"bwmarginl1\">\nTitle: <i>The bispecific antibody zanidatamab\u2019s (ZW25\u2019s) unique mechanisms of action and durable anti-tumor activity in HER2-expressing cancers<br \/>\n<span class=\"bwuline\"><br \/><\/span><\/i>Abstract: 1005<br \/>\n<br \/>Session Category: Experimental and Molecular Therapeutics<br \/>\n<br \/>Session Title: Cellular Responses to Anticancer Drugs\n<\/p>\n<p><b>About Zymeworks Inc. <\/b><\/p>\n<p>\nZymeworks is a clinical-stage biopharmaceutical company dedicated to the development of next-generation multifunctional biotherapeutics. Zymeworks\u2019 suite of therapeutic platforms and its fully integrated drug development engine enable precise engineering of highly differentiated product candidates. Zymeworks\u2019 lead clinical candidate, zanidatamab (ZW25), is a novel Azymetric\u2122 bispecific antibody which has been granted Breakthrough Therapy designation by the FDA and is currently enrolling in a pivotal clinical trial for refractory HER2-amplified biliary tract cancer (HERIZON-BTC-01) as well as several Phase 2 clinical trials for HER2-expressing gastroesophageal and breast cancers. Zymeworks\u2019 second clinical candidate, ZW49, is a novel bispecific HER2-targeting antibody-drug conjugate currently in Phase 1 clinical development and combines the unique design and antibody framework of zanidatamab with Zymeworks\u2019 proprietary ZymeLink\u2122 linker and cytotoxin. Zymeworks is also advancing a deep preclinical pipeline in oncology (including immuno-oncology agents) and other therapeutic areas. In addition, its therapeutic platforms are being leveraged through strategic partnerships with nine biopharmaceutical companies. For additional information about Zymeworks, visit <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.zymeworks.com&amp;esheet=52393569&amp;newsitemid=20210310005992&amp;lan=en-US&amp;anchor=www.zymeworks.com&amp;index=1&amp;md5=6a96774b7bb1fcce88a69e79ad0a33db\">www.zymeworks.com<\/a> and follow <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=https%3A%2F%2Ftwitter.com%2FZymeworksInc&amp;esheet=52393569&amp;newsitemid=20210310005992&amp;lan=en-US&amp;anchor=%40ZymeworksInc&amp;index=2&amp;md5=833043fd7e70e9d67c7ef92828bb989d\">@ZymeworksInc<\/a> on Twitter.\n<\/p>\n<p><b>Cautionary Note Regarding Forward-Looking Statements<\/b><\/p>\n<p>\nThis press release includes \u201cforward-looking statements\u201d within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 and \u201cforward-looking information\u201d within the meaning of Canadian securities laws, or collectively, forward-looking statements. Forward-looking statements in this news release include, but are not limited to, statements that relate to Zymeworks\u2019 clinical and preclinical development of its product candidates, related clinical trials, and other information that is not historical information. When used herein, words such as \u201cwill\u201d, \u201cmay\u201d, and similar expressions are intended to identify forward-looking statements. In addition, any statements or information that refer to expectations, beliefs, plans, projections, objectives, performance or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking. All forward-looking statements are based upon Zymeworks\u2019 current expectations and various assumptions. Zymeworks believes there is a reasonable basis for its expectations and beliefs, but they are inherently uncertain. Zymeworks may not realize its expectations, and its beliefs may not prove correct. Actual results could differ materially from those described or implied by such forward-looking statements as a result of various factors, including, without limitation, market conditions and the factors described under \u201cRisk Factors\u201d in Zymeworks\u2019 Annual Report on Form 10-K for its fiscal year ended December 31, 2020 (a copy of which may be obtained at <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sec.gov&amp;esheet=52393569&amp;newsitemid=20210310005992&amp;lan=en-US&amp;anchor=www.sec.gov&amp;index=3&amp;md5=c3d5ec01f8edf94529eae2de58ae1d64\">www.sec.gov<\/a> and <a rel=\"nofollow\" href=\"https:\/\/cts.businesswire.com\/ct\/CT?id=smartlink&amp;url=http%3A%2F%2Fwww.sedar.com&amp;esheet=52393569&amp;newsitemid=20210310005992&amp;lan=en-US&amp;anchor=www.sedar.com&amp;index=4&amp;md5=66f0cba1c227805f1c05d40d8f00035a\">www.sedar.com<\/a>). Consequently, forward-looking statements should be regarded solely as Zymeworks\u2019 current plans, estimates and beliefs. Investors should not place undue reliance on forward-looking statements. Zymeworks cannot guarantee future results, events, levels of activity, performance or achievements. Zymeworks does not undertake and specifically declines any obligation to update, republish, or revise any forward-looking statements to reflect new information, future events or circumstances or to reflect the occurrences of unanticipated events, except as may be required by law.\n<\/p>\n<p><img decoding=\"async\" alt=\"\" src=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20210310005992r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" style=\"width:0;height:0\" \/><span class=\"bwct31415\" \/><\/p>\n<p id=\"mmgallerylink\"><span id=\"mmgallerylink-phrase\">View source version on businesswire.com: <\/span><span id=\"mmgallerylink-link\"><a href=\"https:\/\/www.businesswire.com\/news\/home\/20210310005992\/en\/\" rel=\"nofollow\">https:\/\/www.businesswire.com\/news\/home\/20210310005992\/en\/<\/a><\/span><\/p>\n<p>\nInvestor Inquiries:<br \/>\n<br \/>Ryan Dercho, Ph.D.<br \/>\n<br \/>(604) 678-1388<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:ir@zymeworks.com\">ir@zymeworks.com<\/a><\/p>\n<p>\nTiffany Tolmie<br \/>\n<br \/>(604) 678-1388<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:ir@zymeworks.com\">ir@zymeworks.com<\/a><\/p>\n<p>\nMedia Inquiries:<br \/>\n<br \/>Mary Klem<br \/>\n<br \/>(604) 678-1388<br \/>\n<br \/><a rel=\"nofollow\" href=\"mailto:media@zymeworks.com\">media@zymeworks.com<\/a><\/p>\n<p><b>KEYWORDS:<\/b> North America Canada<\/p>\n<p><b>INDUSTRY KEYWORDS:<\/b> Biotechnology Health Pharmaceutical Clinical Trials Oncology<\/p>\n<p><b>MEDIA:<\/b><\/p>\n<table cellpadding=\"3\" cellspacing=\"3\">\n<tr>\n<td><font face=\"Arial\" size=\"2\"><b>Logo<\/b><\/font><\/td>\n<\/tr>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/mms.businesswire.com\/media\/20210310005992\/en\/183056\/3\/Logo.jpg\" alt=\"Logo\" \/><\/td>\n<\/tr>\n<tr>\n<td><font face=\"Arial\" size=\"2\"><\/font><\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 VANCOUVER, British Columbia&#8211;(BUSINESS WIRE)&#8211; Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today announced the acceptance of five abstracts for poster presentation at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2021 taking place virtually from April 10 \u2013 15, 2021. The poster presentations will be available on Saturday, April 10 at 8:30 am ET on the conference website as well as the Zymeworks website. Presentation Details Title: PROTECT\u2122, a novel antibody platform for integrating tumor-specific immune modulation and enhancing the therapeutic window of targeted multispecific biologics Abstract: 924 Session Category: Experimental and Molecular Therapeutics Session Title: Antibody Technologies Title: &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-455358","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 VANCOUVER, British Columbia&#8211;(BUSINESS WIRE)&#8211; Zymeworks Inc. (NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today announced the acceptance of five abstracts for poster presentation at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2021 taking place virtually from April 10 \u2013 15, 2021. The poster presentations will be available on Saturday, April 10 at 8:30 am ET on the conference website as well as the Zymeworks website. Presentation Details Title: PROTECT\u2122, a novel antibody platform for integrating tumor-specific immune modulation and enhancing the therapeutic window of targeted multispecific biologics Abstract: 924 Session Category: Experimental and Molecular Therapeutics Session Title: Antibody Technologies Title: &hellip; Continue reading &quot;Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-10T22:30:17+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20210310005992r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021\",\"datePublished\":\"2021-03-10T22:30:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/\"},\"wordCount\":759,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/cts.businesswire.com\\\/ct\\\/CT?id=bwnews&amp;sty=20210310005992r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\\\/\",\"name\":\"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 - 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(NYSE: ZYME), a clinical-stage biopharmaceutical company developing multifunctional biotherapeutics, today announced the acceptance of five abstracts for poster presentation at the upcoming American Association for Cancer Research (AACR) Annual Meeting 2021 taking place virtually from April 10 \u2013 15, 2021. The poster presentations will be available on Saturday, April 10 at 8:30 am ET on the conference website as well as the Zymeworks website. Presentation Details Title: PROTECT\u2122, a novel antibody platform for integrating tumor-specific immune modulation and enhancing the therapeutic window of targeted multispecific biologics Abstract: 924 Session Category: Experimental and Molecular Therapeutics Session Title: Antibody Technologies Title: &hellip; Continue reading \"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/","og_site_name":"Market Newsdesk","article_published_time":"2021-03-10T22:30:17+00:00","og_image":[{"url":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20210310005992r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021","datePublished":"2021-03-10T22:30:17+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/"},"wordCount":759,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/#primaryimage"},"thumbnailUrl":"https:\/\/cts.businesswire.com\/ct\/CT?id=bwnews&amp;sty=20210310005992r1&amp;sid=flmnd&amp;distro=nx&amp;lang=en","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/zymeworks-announces-five-presentations-at-the-american-association-for-cancer-research-aacr-annual-meeting-2021\/","name":"Zymeworks Announces Five Presentations at the American Association for Cancer Research (AACR) Annual Meeting 2021 - 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