{"id":454564,"date":"2021-03-10T07:08:06","date_gmt":"2021-03-10T12:08:06","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=454564"},"modified":"2021-03-10T07:08:06","modified_gmt":"2021-03-10T12:08:06","slug":"ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/","title":{"rendered":"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases"},"content":{"rendered":"
\n

COPENHAGEN, Denmark, March 10, 2021 (GLOBE NEWSWIRE) — Ascendis Pharma A\/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon\u2122 technologies to address unmet medical needs, today announced seven presentations at ENDO 2021, the Endocrine Society\u2019s annual meeting, taking place virtually from March 20-23, 2021.<\/p>\n

\u201cWe are excited to present the 6-month data from our phase 2 PaTH Forward trial in adult hypoparathyroidism for the first time at a scientific conference. These data demonstrate that TransCon PTH can help to reduce or eliminate standard of care treatment, while maintaining serum calcium within the normal range, improving quality of life and driving expected increases in bone remodeling for people with hypoparathyroidism,\u201d said Mark Bach, M.D., Ph.D., Senior Vice President of Endocrine Medical Sciences at Ascendis Pharma. \u201cWe also will present two years of follow-up data for TransCon hGH (lonapegsomatropin), our investigational once-weekly growth hormone, which show durable results in children treated for pediatric growth hormone deficiency, and we will provide additional updates on each of our clinical programs in endocrinology.\u201d<\/p>\n

\n ENDO 2021 Annual Meeting Virtual Event: Presentation Details<\/strong>\n <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n Oral Presentation<\/strong>\n <\/td>\n<\/tr>\n
\n Title<\/strong>\n <\/td>\n\n Date\/Time<\/strong>\n <\/td>\n<\/tr>\n
TransCon PTH as a Hormone Replacement Therapy for Patients with Hypoparathyroidism: 6-Month Update from the PaTH Forward Open-Label Extension.<\/td>\nAbstract Number: 7216.
Oral Session: OR06. Novel Treatments for Metabolic Bone Diseases.
Mar 23, 2021, 2:00\u20133:00 PM.<\/td>\n<\/tr>\n
\n Poster Presentations<\/strong>\n <\/td>\n<\/tr>\n
\n Title<\/strong>\n <\/td>\n\n Date\/Time<\/strong>\n <\/td>\n<\/tr>\n
Efficacy and Safety of up to 2 Years of Treatment with TransCon hGH (lonapegsomatropin) in Treatment-Na\u00efve and Treatment-Experienced Children with Growth Hormone Deficiency.<\/td>\nAbstract Number: 7215.
Poster Session: P33. Growth and Growth Hormone.<\/td>\n<\/tr>\n
Design of the foresiGHt Trial: A Multicenter, Randomized, Placebo- and Active-Controlled Trial to Compare Once-Weekly TransCon hGH (lonapegsomatropin) to Placebo and Daily Somatropin in Adults with Growth Hormone Deficiency (GHD).<\/td>\nAbstract Number: 7942.
Poster Session: P30. Clinical Trials and Study Updates in Neuroendocrinology and Pituitary.<\/td>\n<\/tr>\n
Economic Burden of Growth Hormone Deficiency in a U.S. Pediatric Population.<\/td>\nAbstract Number: 7212.
Poster Session: P33. Growth and Growth Hormone.<\/td>\n<\/tr>\n
Design and Baseline Demographics of a Five-Year, Multi-National Observational Cohort Study of Children with Achondroplasia (ACHieve study)<\/td>\nAbstract Number: 7218.
Poster Session: P35. Pediatric Endocrinology: Adrenal, Thyroid and Genetic Disorders.<\/td>\n<\/tr>\n
Design of the ACcomplisH Trial: A Phase 2, Multicenter, Placebo-controlled, Dose Escalation Trial Evaluating Safety, Efficacy, and Pharmacokinetics of Weekly TransCon CNP in Children with Achondroplasia.<\/td>\nAbstract Number: 7210.
Poster Session: P35. Pediatric Endocrinology: Adrenal, Thyroid, and Genetic Disorders.<\/td>\n<\/tr>\n
Disease Burden of Patients Living with Hypoparathyroidism: Results from the Voices of Hypopara Survey.<\/td>\nAbstract Number: 8810
Poster Session: P08. Parathyroid and Rare Bone Disease<\/td>\n<\/tr>\n<\/table>\n

The posters will be available on the Ascendis website under Selected Publications in the Pipeline section: https:\/\/ascendispharma.us\/pipeline\/publications\/<\/a>. If you are a healthcare provider who would like more information, please contact: medicalaffairs@ascendispharma.com.<\/p>\n

\n About TransCon\u2122 Technology<\/strong>\n <\/p>\n

TransCon refers to \u201ctransient conjugation.\u201d The proprietary TransCon platform is an innovative technology to create new therapies that are designed to optimize therapeutic effect, including efficacy, safety and dosing frequency. TransCon molecules have three components: a parent drug, an inert carrier that protects it, and a linker that temporarily binds the two. When bound, the carrier inactivates and shields the parent drug from clearance. When injected into the body, physiologic conditions (e.g., pH and temperature) initiate the release of the active parent drug in a predictable manner. Once the parent drug is released from the carrier, the parent drug\u2019s distribution and original mode of action is expected to be maintained. TransCon technology can be applied broadly to a protein, peptide or small molecule in multiple therapeutic areas, and can be used systemically or locally.<\/p>\n

\n About\u00a0Ascendis Pharma A\/S\u00a0<\/strong>\n <\/p>\n

Ascendis Pharma\u00a0is applying its innovative platform technology to build a leading, fully integrated biopharma company focused on making a meaningful difference in patients\u2019 lives. Guided by its core values of patients, science and passion, the company utilizes its TransCon technologies to create new and potentially best-in-class therapies.<\/p>\n

Ascendis Pharma currently has a pipeline of three independent endocrinology rare disease product candidates and one oncology product candidate in clinical development. The company continues to expand into additional therapeutic areas to address unmet patient needs.<\/p>\n

Ascendis is headquartered in\u00a0Copenhagen, Denmark, with additional offices in Heidelberg and\u00a0Berlin, Germany, in\u00a0Palo Alto\u00a0and\u00a0Redwood City, California, and in Princeton, New Jersey.<\/p>\n

Please visit www.ascendispharma.com<\/a> (for global information) or www.ascendispharma.us<\/a> (for U.S. information.).<\/p>\n

\n Forward-Looking Statements <\/strong>
\n
This press release contains forward-looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, included in this press release regarding Ascendis\u2019 future operations, plans and objectives of management are forward-looking statements. Examples of such statements include, but are not limited to, statements relating to (i) Ascendis\u2019 ability to apply its platform technology to build a leading, fully integrated biopharmaceutical company, (ii) Ascendis\u2019 product pipeline and expansion into additional therapeutic areas and (iii) Ascendis\u2019 expectations regarding its ability to utilize its TransCon technologies to create new and potentially best-in-class therapies. Ascendis may not actually achieve the plans, carry out the intentions or meet the expectations or projections disclosed in the forward-looking statements and you should not place undue reliance on these forward-looking statements. Actual results or events could differ materially from the plans, intentions, expectations and projections disclosed in the forward-looking statements. Various important factors could cause actual results or events to differ materially from the forward-looking statements that Ascendis makes, including the following: unforeseen safety or efficacy results in its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs; unforeseen expenses related to the development and potential commercialization of its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs, selling, general and administrative expenses, other research and development expenses and Ascendis\u2019 business generally; delays in the development of its oncology programs, TransCon hGH, TransCon PTH and TransCon CNP or other development programs related to manufacturing, regulatory requirements, speed of patient recruitment or other unforeseen delays; dependence on third party manufacturers to supply study drug for planned clinical studies; Ascendis\u2019 ability to obtain additional funding, if needed, to support its business activities and the effects on its business from the worldwide COVID-19 pandemic. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to Ascendis\u2019 business in general, see Ascendis\u2019 prospectus supplement filed on\u00a0July 9, 2020\u00a0and Ascendis\u2019 current and future reports filed with, or submitted to, the\u00a0U.S. Securities and Exchange Commission\u00a0(SEC), including its Annual Report on Form 20-F filed with the\u00a0SEC\u00a0on\u00a0April 3, 2020. Forward-looking statements do not reflect the potential impact of any future in-licensing, collaborations, acquisitions, mergers, dispositions, joint ventures, or investments that Ascendis may enter into or make. Ascendis does not assume any obligation to update any forward-looking statements, except as required by law.<\/p>\n

\n Ascendis,\u00a0Ascendis Pharma, the\u00a0Ascendis Pharma\u00a0logo, the company logo and TransCon are trademarks owned by the\u00a0Ascendis Pharma Group. \u00a9\u00a0March 2021\u00a0Ascendis Pharma A\/S.<\/em>\n <\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
\n Investor contacts:<\/u>
\n <\/strong>\n <\/td>\n		\n
\n Media contact:<\/u>
\n <\/strong>\n <\/td>\n<\/tr>\n
Tim Lee<\/td>\nRon Rogers<\/td>\n<\/tr>\n
Ascendis Pharma<\/td>\nAscendis Pharma<\/td>\n<\/tr>\n
(650) 374-6343<\/td>\n(650) 507-5208<\/td>\n<\/tr>\n
\n tle@ascendispharma.com<\/a>\u00a0<\/td>\n\n rrs@ascendispharma.com<\/a>\u00a0<\/td>\n<\/tr>\n
\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
Patti Bank<\/td>\n\u00a0<\/td>\n<\/tr>\n
Westwicke Partners<\/td>\n\u00a0<\/td>\n<\/tr>\n
(415) 513-1284<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n patti.bank@westwicke.com<\/a>\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n
\n ir@ascendispharma.com<\/a>\u00a0<\/td>\n\u00a0<\/td>\n<\/tr>\n<\/table>\n


\n
\n \n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

COPENHAGEN, Denmark, March 10, 2021 (GLOBE NEWSWIRE) — Ascendis Pharma A\/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon\u2122 technologies to address unmet medical needs, today announced seven presentations at ENDO 2021, the Endocrine Society\u2019s annual meeting, taking place virtually from March 20-23, 2021. \u201cWe are excited to present the 6-month data from our phase 2 PaTH Forward trial in adult hypoparathyroidism for the first time at a scientific conference. These data demonstrate that TransCon PTH can help to reduce or eliminate standard of care treatment, while maintaining serum calcium within the normal range, improving quality of life and driving expected increases in bone remodeling for people with hypoparathyroidism,\u201d said Mark Bach, M.D., Ph.D., Senior Vice President of … <\/p>\n

Continue reading “Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-454564","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nAscendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"COPENHAGEN, Denmark, March 10, 2021 (GLOBE NEWSWIRE) — Ascendis Pharma A\/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon\u2122 technologies to address unmet medical needs, today announced seven presentations at ENDO 2021, the Endocrine Society\u2019s annual meeting, taking place virtually from March 20-23, 2021. \u201cWe are excited to present the 6-month data from our phase 2 PaTH Forward trial in adult hypoparathyroidism for the first time at a scientific conference. These data demonstrate that TransCon PTH can help to reduce or eliminate standard of care treatment, while maintaining serum calcium within the normal range, improving quality of life and driving expected increases in bone remodeling for people with hypoparathyroidism,\u201d said Mark Bach, M.D., Ph.D., Senior Vice President of … Continue reading "Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases"\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-10T12:08:06+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE4NzE1NSM0MDU2MDA3IzIwMTEyMzQ=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Ascendis Pharma A\\\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases\",\"datePublished\":\"2021-03-10T12:08:06+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/\"},\"wordCount\":1199,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE4NzE1NSM0MDU2MDA3IzIwMTEyMzQ=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\\\/\",\"name\":\"Ascendis Pharma A\\\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/","og_locale":"en_US","og_type":"article","og_title":"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases - Market Newsdesk","og_description":"COPENHAGEN, Denmark, March 10, 2021 (GLOBE NEWSWIRE) — Ascendis Pharma A\/S (Nasdaq: ASND), a biopharmaceutical company that utilizes its innovative TransCon\u2122 technologies to address unmet medical needs, today announced seven presentations at ENDO 2021, the Endocrine Society\u2019s annual meeting, taking place virtually from March 20-23, 2021. \u201cWe are excited to present the 6-month data from our phase 2 PaTH Forward trial in adult hypoparathyroidism for the first time at a scientific conference. These data demonstrate that TransCon PTH can help to reduce or eliminate standard of care treatment, while maintaining serum calcium within the normal range, improving quality of life and driving expected increases in bone remodeling for people with hypoparathyroidism,\u201d said Mark Bach, M.D., Ph.D., Senior Vice President of … Continue reading \"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/","og_site_name":"Market Newsdesk","article_published_time":"2021-03-10T12:08:06+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE4NzE1NSM0MDU2MDA3IzIwMTEyMzQ=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases","datePublished":"2021-03-10T12:08:06+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/"},"wordCount":1199,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE4NzE1NSM0MDU2MDA3IzIwMTEyMzQ=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/ascendis-pharma-a-s-announces-seven-presentations-at-endo-2021-demonstrating-commitment-to-people-with-rare-endocrine-diseases\/","name":"Ascendis Pharma A\/S Announces Seven Presentations at ENDO 2021,\u00a0Demonstrating Commitment to People with Rare Endocrine Diseases - 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