{"id":453447,"date":"2021-03-09T07:03:45","date_gmt":"2021-03-09T12:03:45","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=453447"},"modified":"2021-03-09T07:03:45","modified_gmt":"2021-03-09T12:03:45","slug":"kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/","title":{"rendered":"Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS"},"content":{"rendered":"
\n

PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n NESS<\/span> ZIONA, Israel<\/span>, March 9, 2021<\/span> \/PRNewswire\/ — Kadimastem Ltd.<\/a><\/u> (TASE: KDST), a clinical stage cell therapy company, announced that it has been granted a patent by The Israel Patent Office for its differentiated human astrocytes from human pluripotent stem cells for use in the treatment and drug screening of Amyotrophic Lateral Sclerosis (ALS).<\/p>\n

Specifically, the patent allows for the innovative method of non-genetically modifying a cell population of human progenitor astrocytes or astrocytes, for use in the treatment or prevention of the progression of ALS in a human subject in need and screening an agent for preventing or treating Amyotrophic Lateral Sclerosis (ALS) by using this cell population.<\/p>\n

Kadimastem’s flagship product, AstroRx\u00ae<\/sup>, is comprised of a differentiated cell population of human astrocytes derived from human pluripotent stem cells and is in clinical development as a therapeutic treatment for ALS.\u00a0 Kadimastem recently announced encouraging results of the Cohort B of its Phase 1\/2a Clinical Trial of AstroRx\u00ae for ALS. See press release here<\/a>. <\/p>\n

The technology was first initiated at the Weizmann Institute of Science while Professor Michel Revel<\/span>, the co-founder of Kadimastem, was a principal investigator there.\u00a0 It continues to be developed by the experienced and dedicated team in the laboratories of Kadimastem, where Professor Revel serves as the Chief Scientific Officer.<\/p>\n

\n Kadimastem CEO Asaf Shiloni<\/span> said,<\/b>\u00a0“The patent granted by the Israel Patent Office\u00a0is a significant step forward towards bringing AstroRx\u00ae to market for the benefit of ALS patients worldwide.\u00a0 We aim to have a pre-IND meeting with the US FDA in the near future, with the goal of setting in motion the next stage of clinical trials as soon as possible.\u00a0 In the meantime, we shall continue our groundbreaking research and development programs for both our ALS and diabetes products.” <\/p>\n

\n Kadimastem Chief Scientific Officer Professor\u00a0Michel Revel <\/b>added, “Israel<\/span> is an important market for research and development and for setting international medical standards and precedent. Today’s patent is an important milestone that supports producing the cells for AstroRx\u00ae in Israel<\/span> for use worldwide.”<\/p>\n

\n
\n About Kadimastem<\/a>
\n <\/b>\u00a0<\/p>\n

Kadimastem is a clinical stage cell therapy company, developing and manufacturing “off-the-shelf”, allogeneic, proprietary cell products based on its technology platform for the expansion and differentiation of Human Embryonic Stem Cells (hESCs) into functional cells.\u00a0 AstroRx\u00ae, the Company’s lead product, is an astrocyte cell therapy in clinical development as a treatment for ALS.\u00a0 IsletRx is the Company’s second product in development.\u00a0 IsletRx is comprised of functional pancreatic islet cells intended to treat patients with insulin dependent diabetes.\u00a0 IsletRx demonstrated safety and efficacy in a proof-of-concept preclinical study.\u00a0 Kadimastem was founded by Professor Michel Revel<\/span>, CSO of the Company and Professor Emeritus of Molecular Genetics at the Weizmann Institute of Science.\u00a0 Professor Revel received the Israel Prize for the invention and development of Rebif\u00ae, a multiple sclerosis blockbuster drug sold worldwide. Kadimastem is traded on the Tel Aviv Stock Exchange (TASE: KDST).<\/p>\n

\n Forward Looking Statement<\/b>\n <\/p>\n

This document may include forward-looking information as defined in the Securities Law, 5728 \u2013 1968. Forward-looking information is uncertain and mostly is not under the Company’s control and the realization or non-realization of forward-looking information will be affected, among other things, by the risk factors characterizing the Company’s activity, as well as developments in the general environment and external factors affecting the Company’s activity. The Company’s results and achievements in the future may differ materially from any presented herein and the Company makes no undertaking to update or revise such projection or estimate and does not undertake to update this document. This document does not constitute a proposal to purchase the Company’s securities or an invitation to receive such offers. Investment in securities in general and in the Company in particular bears risks. One should consider that past performance does not necessarily indicate performance in the future.<\/p>\n

Social Media: LinkedIn<\/a>, Twitter<\/a>, Facebook<\/a><\/p>\n

\n Company Contacts:
<\/b>Yossi Nizhar
CFO
y.nizhar@kadimastem.com<\/a>
+972-73-797-1604 <\/p>\n

\n Marjie Hadad<\/span>
\n
General Manager
Must Have Communications
917-790-1178
marjie@mhc-pr.com<\/a>\u00a0<\/p>\n

\u00a0<\/p>\n

\u00a0<\/p>\n

\n \"Cision\" View original content:http:\/\/www.prnewswire.com\/news-releases\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als-301243132.html<\/a><\/p>\n

SOURCE Kadimastem<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

PR Newswire NESS ZIONA, Israel, March 9, 2021 \/PRNewswire\/ — Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company, announced that it has been granted a patent by The Israel Patent Office for its differentiated human astrocytes from human pluripotent stem cells for use in the treatment and drug screening of Amyotrophic Lateral Sclerosis (ALS). Specifically, the patent allows for the innovative method of non-genetically modifying a cell population of human progenitor astrocytes or astrocytes, for use in the treatment or prevention of the progression of ALS in a human subject in need and screening an agent for preventing or treating Amyotrophic Lateral Sclerosis (ALS) by using this cell population. Kadimastem’s flagship product, AstroRx\u00ae, is comprised of a differentiated … <\/p>\n

Continue reading “Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-453447","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nKadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"PR Newswire NESS ZIONA, Israel, March 9, 2021 \/PRNewswire\/ — Kadimastem Ltd. 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(TASE: KDST), a clinical stage cell therapy company, announced that it has been granted a patent by The Israel Patent Office for its differentiated human astrocytes from human pluripotent stem cells for use in the treatment and drug screening of Amyotrophic Lateral Sclerosis (ALS). Specifically, the patent allows for the innovative method of non-genetically modifying a cell population of human progenitor astrocytes or astrocytes, for use in the treatment or prevention of the progression of ALS in a human subject in need and screening an agent for preventing or treating Amyotrophic Lateral Sclerosis (ALS) by using this cell population. Kadimastem’s flagship product, AstroRx\u00ae, is comprised of a differentiated … Continue reading \"Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/","og_site_name":"Market Newsdesk","article_published_time":"2021-03-09T12:03:45+00:00","og_image":[{"url":"https:\/\/c212.net\/c\/img\/favicon.png?sn=LN03369&sd=2021-03-09","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"3 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS","datePublished":"2021-03-09T12:03:45+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/"},"wordCount":693,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/#primaryimage"},"thumbnailUrl":"https:\/\/c212.net\/c\/img\/favicon.png?sn=LN03369&sd=2021-03-09","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/kadimastem-granted-a-patent-in-israel-for-the-directed-differentiation-of-astrocytes-from-human-pluripotent-stem-cells-astrorx-for-use-in-drug-screening-and-the-treatment-of-als\/","name":"Kadimastem Granted a Patent in Israel for the Directed Differentiation of Astrocytes from Human Pluripotent Stem Cells (AstroRx\u00ae) for use in Drug Screening and the Treatment of ALS - 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