{"id":450437,"date":"2021-03-04T07:03:47","date_gmt":"2021-03-04T12:03:47","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=450437"},"modified":"2021-03-04T07:03:47","modified_gmt":"2021-03-04T12:03:47","slug":"hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\/","title":{"rendered":"Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity"},"content":{"rendered":"<h2>\nCompany to Host Annual Results Call &amp; Webcast Today at 1 p.m. GMT \/ 8 a.m. EST \/ 9 p.m. HKT<br \/>\n<\/h2>\n<div class=\"mw_release\">\n<p align=\"justify\">HONG KONG and SHANGHAI and FLORHAM PARK, N.J., March  04, 2021  (GLOBE NEWSWIRE) &#8212; Hutchison China MediTech Limited (\u201c<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=wvWoD-QhUdtz5IPLLbM6pFBQcGiBtW8HjZUDyD-GioNRstFBsypaKgendskzjJr7OS2RjsXdBKW5IkBjUO1UlA==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">HUTCHMED<\/a>\u201d) (Nasdaq\/AIM: HCM), an innovation-driven, commercial-stage biopharmaceutical company, today reports its audited financial results for the year ended December 31, 2020 and provides updates on key clinical and commercial developments.\u00a0\u00a0 The Company also intends to seek shareholders\u2019 approval to change its name to HUTCHMED (China) Limited at its forthcoming Annual General Meeting. For more information on the new corporate name, see <em>2020 Full Year Results &amp; Business Updates\u2014VI.\u00a0Evolution of Our Corporate Identity<\/em>.<\/p>\n<p>\n        <strong>2020 FULL YEAR RESULTS &amp; BUSINESS UPDATES<\/strong>\n      <\/p>\n<p align=\"justify\">\u201cAt the heart of HUTCHMED lies a prolific in-house novel drug discovery and development engine that has produced ten clinical-stage drug candidates and a further seven late-stage preclinical assets in oncology and immunology over the past fifteen years.\u201d said Mr. Simon To, Chairman of HUTCHMED. \u201cOur aim is to bring these internally discovered and developed innovations to patients the world-over.\u201d<\/p>\n<p align=\"justify\">\u201cTo support this strategic objective, we have built an oncology and immunology operation with around 1,200 personnel based mainly in our two core markets, China and the U.S. In China, supported by a robust manufacturing infrastructure, our commercial team is now delivering impressive sales results on our first two oncology drugs, ELUNATE<sup>\u00ae<\/sup> in metastatic colorectal cancer and the recently launched SULANDA<sup>\u00ae<\/sup> in neuroendocrine tumors. A New Drug Application was also submitted mid-last year for savolitinib in lung cancer and, subject to approval, it will be our third approved oncology drug and the first-in-class selective MET inhibitor on the market in China.\u201d<\/p>\n<p align=\"justify\">\u201cOutside China, our fast expanding international organization, led mainly from the U.S., is developing five un-partnered oncology drug candidates. In 2020, it achieved three U.S. Food and Drug Administration fast track designations and initiated the rolling submission of surufatinib, our first U.S. New Drug Application filing.\u201d\u00a0\u00a0<\/p>\n<p align=\"justify\">\u201cOver the next three years, we will continue to grow our R&amp;D and commercial organizations globally to support the anticipated launch of our oncology drugs in China, the U.S. and Europe.\u201d<\/p>\n<p align=\"justify\">\n        <strong>I. COMMERCIAL OPERATIONS<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Full year 2021 Oncology\/Immunology consolidated revenues guidance $110-130 million<\/strong> (2020 actual: $30.2m) with in-house oncology commercial organization in China now expanded to over 420 personnel (end 2019: about 90) covering over 2,300 oncology hospitals and over 20,000 oncology physicians;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>ELUNATE<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae <\/strong><br \/>\n          <\/sup><br \/>\n          <strong>(fruquintinib) in-market sales increased 91% to $33.7 million<\/strong><br \/>\n          <sup><br \/>\n            <strong>1<\/strong><br \/>\n          <\/sup> (2019: $17.6m), as provided by Lilly<sup>2<\/sup>, during 2020 as a result of inclusion in the 2020 China NRDL<sup>3<\/sup>;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Accelerating sales growth on ELUNATE<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae <\/strong><br \/>\n          <\/sup>since Q4 2020 when HUTCHMED assumed responsibility for all on-the-ground medical detailing, promotion and local and regional marketing activities in China;\u00a0\u00a0 <\/li>\n<\/ul>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"border-top: solid black 1pt;vertical-align: top\">\n            <em>(Growth vs. Prior Period)<\/em>\n          <\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Lilly Sales Team<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">HUTCHMED Sales Team<\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">2020<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Q1-Q3 2020<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Q4 2020<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Jan-Feb 2021*<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">ELUNATE<sup>\u00ae<\/sup> In-market Sales<em>**<\/em><\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: top\">$33.7m <em>(+91%)<\/em><\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: top\">$23.5m (+37%)<\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$10.2m <em>(+2,051%)<\/em><\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$14.3m <em>(+116%)<\/em><\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: top\">ELUNATE<sup>\u00ae <\/sup>Revenues consolidated by HUTCHMED<em>***<\/em><\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$20.0m <em>(+85%)<\/em><\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$12.8m (+53%)<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$7.2m <em>(+192%)<\/em><\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$10.2m <em>(+269%)<\/em><\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <em>* = Unaudited; ** = Represents total sales to third parties as provided by Lilly; *** = Represents manufacturing fees, commercial service fees and royalties paid by Lilly to HUTCHMED, and sales to other third parties invoiced by HUTCHMED.<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Launched SULANDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> (surufatinib) <\/strong>as a treatment for patients with advanced non-pancreatic NET<sup>4<\/sup> in China in mid-January 2021 within three weeks of approval. Unaudited sales of SULANDA<sup>\u00ae<\/sup> in January-February 2021, in its first two months on the market, were $4.9 million; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Established our U.S. commercial organization<\/strong> with the recruitment of senior leadership team based in New Jersey to prepare launch readiness for the potential surufatinib U.S. approval in late 2021 or early 2022.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>II. REGULATORY ACHIEVEMENTS<\/strong>\n      <\/p>\n<p align=\"justify\">\n        <strong>China<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Received China approval for SULANDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup> from the China NMPA<sup>5<\/sup> as a treatment for patients with advanced non-pancreatic NET in December 2020;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Submitted a China NDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>6<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> for savolitinib <\/strong>as a treatment for patients with MET<sup>7<\/sup> Exon 14 skipping alteration NSCLC<sup>8<\/sup>. The NDA was accepted in May 2020. Priority Review status was granted in July 2020 and review is underway;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Submitted a second China NDA for SULANDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup> as a treatment for patients with advanced pancreatic NET. The NDA was accepted in September 2020 and review is underway; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>IND<\/strong><br \/>\n          <sup><br \/>\n            <strong>9<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> cleared for HMPL-295<\/strong>, a novel ERK<sup>10<\/sup> inhibitor in the MAPK pathway<sup>11<\/sup>, in late 2020.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>United States &amp; Europe<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiated surufatinib U.S. FDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>12<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> rolling submission <\/strong>of a NDA for the treatment of both pancreatic and non-pancreatic NET in December 2020;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Secured U.S. FDA Fast Track Designations for surufatinib<\/strong> for the treatment of both pancreatic and non-pancreatic NET in April 2020;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Received scientific advice from the EMA<\/strong><br \/>\n          <sup><br \/>\n            <strong>13<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> CHMP<\/strong><br \/>\n          <sup><br \/>\n            <strong>14<\/strong><br \/>\n          <\/sup> for surufatinib for the treatment of both pancreatic and non-pancreatic NET with no MAA<sup>15<\/sup> filing issues identified;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Secured U.S. FDA Fast Track Designation for fruquintinib<\/strong> for the treatment of advanced CRC<sup>16<\/sup> in June 2020; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Cleared two U.S. FDA INDs for HMPL-306 <\/strong>in late 2020, in hematological malignancies and solid tumors.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>III. CLINICAL DEVELOPMENT ACTIVITIES <\/strong>\n      <\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>Surufatinib<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em> (SULANDA<\/em><br \/>\n        <sup><br \/>\n          <em>\u00ae<\/em><br \/>\n        <\/sup><br \/>\n        <em> in China), a small molecule inhibitor of VEGFR<\/em><br \/>\n        <sup><br \/>\n          <em>17<\/em><br \/>\n        <\/sup><br \/>\n        <em>, FGFR<\/em><br \/>\n        <sup><br \/>\n          <em>18<\/em><br \/>\n        <\/sup><br \/>\n        <em> and CSF-1R<\/em><br \/>\n        <sup><br \/>\n          <em>19<\/em><br \/>\n        <\/sup><br \/>\n        <em> designed to inhibit tumor angiogenesis and promote the body\u2019s immune response against tumor cells via tumor associated macrophage regulation; approved and launched in China<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase III study in pancreatic NET (SANET-p)<\/strong> (NCT02589821) at the ESMO<sup>20<\/sup> Congress 2020 and published simultaneously in The Lancet Oncology. The study met all primary and secondary endpoints and supported NMPA NDA submission;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented preliminary data of U.S. Phase Ib NET cohorts<\/strong> (NCT02549937) at the ASCO<sup>21<\/sup> Conference 2020 in heavily pretreated patients with pancreatic or non-pancreatic NET, demonstrating encouraging efficacy in patients refractory or intolerant to AFINITOR<sup>\u00ae<\/sup> and SUTENT<sup>\u00ae<\/sup>;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented pharmacokinetic and safety data of U.S. Phase Ib NET cohorts<\/strong> (NCT02549937) at the AACR<sup>22<\/sup> Conference 2020, demonstrating similar profiles of surufatinib between Chinese and U.S. patients; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase I dose-finding study for surufatinib plus TUOYI<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup>, Junshi\u2019s<sup>23<\/sup> anti-PD-1<sup>24<\/sup> antibody, (NCT04169672) at the AACR Conference 2020. Data demonstrated that surufatinib plus TUOYI<sup>\u00ae<\/sup> were well tolerated with encouraging antitumor activity in patients with advanced solid tumors. In January 2020, we initiated a Phase II study in nine solid tumor indications in China.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for Surufatinib:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete the U.S. FDA rolling NDA submission<\/strong> for the treatment of both pancreatic and non-pancreatic NET in the first half of 2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase Ib\/II study of surufatinib in combination with tislelizumab<\/strong> (NCT04579757), BeiGene\u2019s<sup>25<\/sup> PD-1 antibody, in the U.S. in the first half of 2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Submit the EU MAA<\/strong> for the treatment of both pancreatic and non-pancreatic NET in mid-2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Present Phase II data for the SULANDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> plus TUOYI<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup> combination in select indications in mid-2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Receive China approval for patients with advanced pancreatic NET<\/strong> which may occur as early as the second half of 2021; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate Phase III pivotal studies for the SULANDA<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> plus TUOYI<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup> combination in select indications in the second half of 2021 and beyond.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>Fruquintinib<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em>(ELUNATE<\/em><br \/>\n        <sup><br \/>\n          <em>\u00ae<\/em><br \/>\n        <\/sup><br \/>\n        <em> in China),<\/em><br \/>\n        <em>a highly selective small molecule inhibitor of VEGFR 1\/2\/3 designed to improve kinase selectivity to minimize off-target toxicity and thereby improve tolerability; approved and launched in China<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiated a global Phase III registration study<\/strong> (NCT04322539), the FRESCO-2 study, in refractory metastatic CRC. FRESCO-2 is expected to enroll over 680 patients from over 150 sites in 14 countries. The first patient was dosed in September 2020 in the U.S.;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented preliminary data of U.S. Phase I\/Ib colorectal cancer cohorts<\/strong> (NCT03251378) at the ESMO Congress 2020 in heavily pretreated metastatic CRC patients, demonstrating encouraging efficacy and tolerability in patients refractory or intolerant to STIVARGA<sup>\u00ae<\/sup> and LONSURF<sup>\u00ae<\/sup>;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Completed second planned interim data review for a Phase III<\/strong> registration study (NCT03223376), the FRUTIGA study, in advanced gastric cancer. Based on preset criteria the IDMC<sup>26<\/sup> and Joint Steering Committees recommended that the trial continue with a sample size increase to ~700 patients; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiated a Phase II study for fruquintinib in combination with TYVYT<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup>, Innovent\u2019s<sup>27<\/sup> PD-1 antibody, in four solid tumor indications (NCT03903705) in Q4 2020.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for Fruquintinib:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase Ib\/II study in the U.S. for fruquintinib in combination with tislelizumab <\/strong>(NCT04577963) in patients with advanced, refractory triple negative breast cancer in the first half of 2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Present Phase Ib U.S. expansion data<\/strong> in metastatic CRC (NCT03251378) in mid-2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Present preliminary Phase Ib data for fruquintinib plus TYVYT<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> (NCT04179084) and<\/strong><br \/>\n          <strong>fruquintinib plus geptanolimab<\/strong><br \/>\n          <strong>(NCT03977090)<\/strong> in CRC in mid-2021;\u00a0\u00a0<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate pivotal studies for the ELUNATE<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> plus anti-PD-1 antibody<\/strong> combination in select indications in the second half of\u00a02021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete enrollment of the FRESCO-2 study<\/strong> (NCT04322539) in refractory metastatic CRC in late-2021; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete enrollment of the FRUTIGA study<\/strong> (NCT03223376) in advanced gastric cancer in late-2021;<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>Savolitinib<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n          <em>,<\/em><br \/>\n        <\/strong><br \/>\n        <em>a highly selective small molecule inhibitor of MET being developed broadly across MET-driven patient populations in lung and gastric cancer and renal cell carcinoma \u00a0<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase II registration study<\/strong> (NCT02897479) for savolitinib in MET Exon 14 skipping mutation patients at the ASCO Conference 2020 which met study endpoints and supported NMPA NDA submission;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase II data for the CALYPSO study<\/strong> (NCT02819596) for savolitinib in combination with IMFINZI<sup>\u00ae<\/sup>, AstraZeneca\u2019s<sup>28<\/sup> PD-L1<sup>29<\/sup> antibody, in PRCC<sup>30<\/sup> patients at the ASCO GU<sup>31<\/sup> Conference 2020 demonstrating encouraging synergy in efficacy and tolerability in line with single agent safety profiles;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase III data for the SAVOIR study<\/strong> (NCT03091192) for savolitinib in MET positive PRCC patients at the ASCO Conference 2020 showing a clear trend to superiority in efficacy and tolerability versus SUTENT<sup>\u00ae<\/sup> in first 60 patient data; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented final Phase II data for TATTON<\/strong> (NCT02143466) at WCLC<sup>32<\/sup> 2020, a global exploratory study in NSCLC aiming to recruit patients with MET amplification who had progressed after prior treatment with EGFR<sup>33<\/sup> inhibitors. TATTON clearly confirmed the importance of the savolitinib plus TAGRISSO<sup>\u00ae<\/sup> combination.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for Savolitinib:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Potential receipt of approval in China<\/strong> for the treatment of patients with MET Exon 14 skipping alteration NSCLC which may occur as early as Q2 2021, enabling a $25 million first sale milestone payment from AstraZeneca. If approved, savolitinib would be the first-in-class selective MET inhibitor in China;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate global Phase III pivotal studies for the savolitinib plus IMFINZI<\/strong><br \/>\n          <sup><br \/>\n            <strong>\u00ae<\/strong><br \/>\n          <\/sup> combination in MET positive PRCC in mid-2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate Phase II study with potential for registration<\/strong> intent for savolitinib in metastatic gastric cancer in China in mid-2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Conclude the SAVANNAH Phase II study<\/strong> (NCT03778229) for the savolitinib plus TAGRISSO<sup>\u00ae<\/sup> combination in NSCLC patients harboring EGFR mutation and MET amplification or overexpression. SAVANNAH will inform final regulatory, biomarker and dose regimen strategy for global Phase III development in the second half of 2021; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate two further pivotal Phase III studies<\/strong> in China in NSCLC patients in the second half of 2021.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>HMPL-689, <\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em>an investigative and highly selective small molecule inhibitor of PI3K<\/em><br \/>\n        <em>\u03b4<\/em><br \/>\n        <sup><br \/>\n          <em>34<\/em><br \/>\n        <\/sup><br \/>\n        <em> designed to address the gastrointestinal and hepatotoxicity associated with currently approved and clinical-stage PI3K\u03b4 inhibitors\u00a0 <\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Presented Phase I dose escalation data<\/strong> (NCT03128164) for HMPL-689 in patients in China with relapsed\/refractory lymphoma at the ASH<sup>35<\/sup> Annual Meeting 2020 demonstrating encouraging efficacy and tolerability profile.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for HMPL-689:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete Phase Ib expansion study <\/strong>(NCT03128164) and present interim data in the second half of 2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate Phase II studies with potential for registration<\/strong> intent in China in multiple relapsed\/refractory non-Hodgkin\u2019s lymphoma indications during 2021;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete Phase I dose escalation in the U.S. and Europe<\/strong> (NCT03786926) in Q2 2021 and initiate Phase Ib expansion studies in multiple non-Hodgkin\u2019s lymphoma indications; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Complete U.S. FDA regulatory discussions<\/strong> in the second half of 2021 followed by the initiation of registration intent studies in indolent non-Hodgkin\u2019s lymphoma by the end of 2021.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>HMPL-523<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em><br \/>\n          <em>, <\/em><br \/>\n        <\/em><br \/>\n        <em>an investigative and highly selective small molecule inhibitor of Syk<\/em><br \/>\n        <sup><br \/>\n          <em>36<\/em><br \/>\n        <\/sup><br \/>\n        <em>, an important component of the B-cell receptor signaling pathway, <\/em><br \/>\n        <em>for the treatment of hematological cancers and immune disease<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Completed enrollment of Phase I<\/strong> dose escalation study (NCT03779113) in the U.S. and Europe; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Completed enrollment of Phase I\/Ib <\/strong>study (NCT03951623) in China of HMPL-523 in ITP<sup>37<\/sup>.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for HMPL-523:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase III study<\/strong> in ITP in China in the second half of 2021. <\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>HMPL-453,<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em>an investigative and highly selective small molecule inhibitor of FGFR 1\/2\/3<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiated a Phase II study<\/strong> (NCT04353375) in China in patients with advanced IHCC<sup>38<\/sup> with FGFR2<sup>39<\/sup> fusion that had failed at least one line of systemic therapy.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>HMPL-306, <\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em>an investigative and highly selective small molecule inhibitor of IDH1\/2<\/em><br \/>\n        <sup><br \/>\n          <em>40<\/em><br \/>\n        <\/sup><br \/>\n        <em> designed to address resistance to the currently marketed IDH inhibitors<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiated a Phase I dose escalation study<\/strong> (NCT04272957) in China in patients with relapsed or refractory hematological malignancies with an IDH1 and\/or IDH2 mutation.<\/li>\n<\/ul>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for HMPL-306:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase I dose escalation study<\/strong> in the U.S. in patients with relapsed or refractory hematological malignancies with an IDH1 and\/or IDH2 mutation in the first half of 2021; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase I dose escalation study<\/strong> in the U.S. in patients with solid tumors with an IDH1 and\/or IDH2 mutation in the first half of 2021.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>HMPL-295<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em><br \/>\n          <em>, <\/em><br \/>\n        <\/em><br \/>\n        <em>an investigative and highly selective small molecule inhibitor of ERK in the MAPK pathway with the potential to address intrinsic or acquired resistance from upstream mechanisms such as RAS-RAF-MEK. <\/em>\n      <\/p>\n<p>\n        <em>Potential upcoming clinical and regulatory milestones for HMPL-295:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Initiate a Phase I study in China <\/strong>in mid-2021<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong><br \/>\n          <strong><br \/>\n            <em><br \/>\n              <em>Discovery<\/em><br \/>\n            <\/em><br \/>\n          <\/strong><br \/>\n        <\/strong><br \/>\n        <em>, our in-house scientific team has been responsible for the discovery of all ten of our clinical drug candidates including our two approved oncology drugs ELUNATE<\/em><br \/>\n        <sup><br \/>\n          <em>\u00ae<\/em><br \/>\n        <\/sup><br \/>\n        <em> and SULANDA<\/em><br \/>\n        <sup><br \/>\n          <em>\u00ae<\/em><br \/>\n        <\/sup>\n      <\/p>\n<p>\n        <em>Potential upcoming discovery milestones:<\/em>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>IND-enabling toxicity studies are underway for three additional in-house discovered oncology drug candidates<\/strong>, two small molecules and one antibody. If the outcomes of these studies are as we anticipate, we will follow with IND submissions during 2021.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>IV. MANUFACTURING OPERATIONS<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Received surufatinib update to drug manufacturing license <\/strong>at our Suzhou manufacturing facility, following the NMPA approval in December 2020; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Broke ground in December 2020 on our $130 million new Shanghai manufacturing facility<\/strong> designed to support a five-fold increase in small molecule drug product manufacturing capacity relative to our existing Suzhou facilities. We plan also that in the future the Shanghai facility will also establish scale biologics manufacturing capability.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>V. OTHER CORPORATE DEVELOPMENTS<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Announced a clinical collaboration agreement with BeiGene<\/strong> in May 2020 to evaluate combining surufatinib and fruquintinib with BeiGene\u2019s anti-PD-1 antibody tislelizumab, for the treatment of various solid tumor cancers, in the U.S., Europe, China and Australia;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Announced a land compensation agreement<\/strong> in June 2020 with the Guangzhou government for the return of the remaining 34-year land-use rights on an unused plot of land under our HBYS<sup>41<\/sup> joint venture in consideration for cash compensation of up to approximately $100 million; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Announced a strategic partnership with Inmagene<\/strong><br \/>\n          <sup><br \/>\n            <strong>42<\/strong><br \/>\n          <\/sup> in January 2021 to further develop four novel preclinical drug candidates discovered by HUTCHMED for the potential treatment of multiple immunological diseases.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>VI. EVOLUTION OF OUR CORPORATE IDENTITY<\/strong>\n      <\/p>\n<p align=\"justify\">Today we announce the consolidation of the two corporate identities that we have used since our inception. Hutchison China MediTech, or Chi-Med, has been used as our group identity, while Hutchison MediPharma has been the identity of our novel drug R&amp;D<sup>43<\/sup> operations under which our oncology products have been developed and are now being marketed. We believe now is the right time to consolidate to a single and ubiquitous corporate identity that captures the history and brand equity we have built over the past twenty years.<\/p>\n<p align=\"justify\">Therefore, we have chosen to rename ourselves HUTCHMED. The brand HUTCHMED will immediately replace Chi-Med as our abbreviated name. We plan to formally change our group company name at our Annual General Meeting in April 2021, and the names of our key subsidiary companies over the balance of 2021. Our ticker symbol, HCM, will remain unchanged on the Nasdaq Global Select Market and the AIM market of the London Stock Exchange. We have also changed our website to www.hutch-med.com. The information required pursuant to AIM Rule 26 may be found at this address.<\/p>\n<p align=\"justify\">\n        <strong>VII. IMPACT OF COVID-19<\/strong>\n      <\/p>\n<p align=\"justify\">The COVID-19 outbreak initially posed some challenges to our operations in 2020 resulting from restrictions in travel. Our teams adapted quickly and were able to minimize the effect across our businesses. We will continue to closely monitor the evolving situation.<\/p>\n<p>\n        <strong>FULL YEAR 2020 FINANCIAL RESULTS<\/strong>\n      <\/p>\n<p align=\"justify\">\n        <strong>Change in Segment Reporting: <\/strong>\n      <\/p>\n<p align=\"justify\">As a consequence of our recent commercialization of both ELUNATE<sup>\u00ae<\/sup> and SULANDA<sup>\u00ae<\/sup> and the possible approval and launch of savolitinib during 2021, we have decided to change the manner in which we report segment results in our financial statements. Effective from the year ended December 31, 2020, we will report two segments, (1) Oncology\/Immunology, covering all activities related to oncology\/immunology including sales, marketing, manufacturing and research and development with respect to our drugs and drug candidates; and (2) Other Ventures, which includes all other HUTCHMED businesses. We have retrospectively revised prior period segment information to conform to current period presentation in the financial information contained in this announcement.<\/p>\n<p align=\"justify\">\n        <strong>Cash, Cash Equivalents and Short-Term Investments were $435.2 million as of December 31, 2020 compared to $217.2 million as of December 31, 2019.<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">Adjusted Group (non-GAAP<sup>44<\/sup>) net cash flows excluding financing activities were -$78.4 million (2019: -$82.3m) mainly due to Oncology\/Immunology R&amp;D spending and partially offset by dividends received from our non-consolidated joint ventures totaling $86.7 million (2019: $28.1m); and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">Net cash generated from financing activities in 2020 totaled $296.4 million (2019: -$1.5m) mainly resulting from a Nasdaq follow-on offering in January 2020 and two private placements to General Atlantic<sup>45<\/sup> and CPP Investments<sup>46<\/sup> completed in July and November 2020 respectively.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Revenues for the year ended December 31, 2020 was $228.0 million compared to $204.9 million in\u00a02019. <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Oncology\/Immunology consolidated revenues<\/strong> were $30.2 million (2019: $26.8m) comprised of $20.0 million (2019: $10.8m) in manufacturing revenues, promotion and marketing service revenues and royalties from the commercial sale of ELUNATE<sup>\u00ae<\/sup>; and $10.2 million (2019: $16.0m) in research and development service fee revenues primarily from AstraZeneca and Lilly; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Other Ventures consolidated revenues<\/strong> increased 11% (11% at CER<sup>47<\/sup>) to $197.8 million (2019: $178.1m) mainly due to continued sales growth of third-party prescription drug products.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Net Expenses<\/strong><br \/>\n        <strong>for the year ended December 31, 2020 were $353.7 million compared to $310.9 million in 2019. <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Cost of Sales<\/strong> were $188.5 million (2019: $160.2m), the majority of which was the cost of third-party prescription drug products marketed through our profitable Other Ventures;<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>R&amp;D Expenses <\/strong>were $174.8 million (2019: $138.2m) mainly as a result of an expansion in the development of our ten novel oncology drug candidates. With six now in global development, our rapidly scaling international clinical and regulatory operations in the U.S. and Europe incurred expenses of $63.3 million (2019: $21.7m) while R&amp;D expense in China was stable at $111.5 million (2019: $116.5m);<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>SG&amp;A<\/strong><br \/>\n          <sup><br \/>\n            <strong>48<\/strong><br \/>\n          <\/sup><br \/>\n          <strong> Expenses <\/strong>were $61.3 million (2019: $52.9m) primarily due to increases in staff costs and share-based compensation to support expanding operations. This included the build-up of a large-scale national oncology commercial infrastructure in China to support the launch of SULANDA<sup>\u00ae<\/sup> and the assumption of commercial responsibility on ELUNATE<sup>\u00ae<\/sup>; and<\/li>\n<li style=\"margin-top:9pt;text-align:justify\">\n          <strong>Other Items<\/strong><br \/>\n          <sup><br \/>\n            <strong>49<\/strong><br \/>\n          <\/sup> generated net income of $70.9 million (2019: $40.4m) resulting primarily from an increase in our share of equity in the earnings from equity investees under our Other Ventures in China which delivered solid underlying net income growth of 7% (9% at CER) in 2020 and also benefited from a one-time land compensation gain of $28.8 million (2019: nil).<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Net Loss<\/strong><br \/>\n        <strong>attributable to HUTCHMED for the year ended December 31, 2020 was $125.7 million compared to $106.0 million in 2019. <\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-top:9pt;text-align:justify\">As a result, the net loss attributable to HUTCHMED in 2020 was $0.18 per ordinary share\u00a0\/ $0.90 per ADS<sup>50<\/sup> compared to net loss attributable to HUTCHMED of $0.16 per ordinary share\u00a0\/ $0.80 per ADS, in 2019. <\/li>\n<\/ul>\n<p>\n        <strong>FINANCIAL SUMMARY<\/strong>\n      <\/p>\n<p>\n        <strong>Condensed Consolidated Balance Sheet Data<br \/><\/strong>(in $\u2019000)<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td colspan=\"3\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>As of December 31,<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:74%;width:74%;min-width:74%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;vertical-align: top\">\u00a0<\/td>\n<td style=\"max-width:12%;width:12%;min-width:12%;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2020<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:12%;width:12%;min-width:12%;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2019<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Assets<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Cash and cash equivalents and short term investments<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">435,176<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">217,168<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Accounts receivable<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">47,870<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">43,254<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Other current assets<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">47,694<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">56,600<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Property, plant and equipment<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">24,170<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">20,855<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Investments in equity investees<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">139,505<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">98,944<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Other non-current assets<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">29,703<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">28,301<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Total assets<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>724,118<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>465,122<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Liabilities and shareholders\u2019 equity<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Accounts payable<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">31,612<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">23,961<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Other payables, accruals and advance receipts<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">120,882<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">81,624<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Long-term bank borrowings<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">26,861<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">26,818<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: top\">Other liabilities<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">25,814<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">19,816<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Total liabilities<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>205,169<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>152,219<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Total Company\u2019s shareholders\u2019 equity<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>484,116<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>288,012<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">Non-controlling interests<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">34,833<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">24,891<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Total liabilities and shareholders\u2019 equity<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>724,118<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>465,122<\/strong>\n          <\/td>\n<\/tr>\n<\/table>\n<p>\n        <strong>Condensed Consolidated Statement of Operations Data<\/strong>\n      <\/p>\n<p align=\"justify\">(in $\u2019000, except share and per share data)<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"5\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Year Ended December 31,<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:75%;width:75%;min-width:75%;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2020<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>2019<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Revenues:<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Oncology\/Immunology \u2013 Marketed Products<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">19,953<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">10,766<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Oncology\/Immunology \u2013 R&amp;D<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">10,262<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">16,026<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Oncology\/Immunology consolidated revenues<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">30,215<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">26,792<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Other Ventures<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">197,761<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">178,098<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<strong> Total revenues<\/strong><\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>227,976<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>204,890<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Expenses:<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-top: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-top: double black 3pt;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Costs of revenues<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(188,519<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(160,152<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Research and development expenses<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(174,776<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(138,190<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Selling and general administrative expenses<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(61,349<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(52,934<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong> Total expenses<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(424,644<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(351,276<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Loss from Operations<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(196,668<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(146,386<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Other income<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">6,934<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">5,281<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Loss before income taxes and equity in earnings of equity investees<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(189,734<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(141,105<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Income tax expense<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(4,829<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(3,274<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 15.0px;vertical-align: bottom\">Equity in earnings of equity investees, net of tax<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">79,046<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">40,700<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Net loss<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(115,517<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(103,679<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Less: Net income attributable to non-controlling interests<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(10,213<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(2,345<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n            <strong>Net loss attributable to HUTCHMED<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(125,730<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(106,024<\/strong>\n          <\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: double 15px 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n<p>            <strong>Losses per share attributable to HUTCHMED &#8211; basic and diluted<\/strong>\n          <\/td>\n<td style=\"border-top: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(0.18<\/strong>\n          <\/td>\n<td style=\"border-top: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-top: double black 3pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(0.16<\/strong>\n          <\/td>\n<td style=\"border-top: double black 3pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Number of shares used in per share calculation &#8211; basic and diluted<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">697,931,437<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">665,683,145<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">\n<p>            <strong>Losses per ADS attributable to HUTCHMED &#8211; basic and diluted<\/strong>\n          <\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(0.90<\/strong>\n          <\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>(0.80<\/strong>\n          <\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\n            <strong>)<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: bottom\">Number of ADSs used in per share calculation &#8211; basic and diluted<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">139,586,287<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">133,136,629<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <em>All amounts are expressed in U.S. dollar currency unless otherwise stated.<\/em>\n      <\/p>\n<p>\n        <strong>FINANCIAL GUIDANCE<\/strong>\n      <\/p>\n<p align=\"justify\">We provide select Financial Guidance for 2021 below reflecting expected commercial progress on ELUNATE<sup>\u00ae<\/sup> and SULANDA<sup>\u00ae<\/sup> as well as the potential launch of savolitinib in mid-2021. While we do not provide net cash flow guidance for 2021, we do expect an increase in investment to support the many new potential registration studies we plan this year as well as the continued expansion of our organization in China, the U.S. and Europe.\u00a0<\/p>\n<p align=\"justify\">To support our growth plans, we continue to actively evaluate non-core assets divestment opportunities as well as monitor market conditions for seeking further listings on other stock exchanges such as Hong Kong and Shanghai.<\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"max-width:70%;width:70%;min-width:70%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">\u00a0<\/td>\n<td style=\"max-width:15%;width:15%;min-width:15%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\n            <strong>2020<\/strong><br \/>\n            <br \/>\n            <strong>Actual<\/strong>\n          <\/td>\n<td style=\"max-width:15%;width:15%;min-width:15%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: middle\">\n            <strong>2021<\/strong><br \/>\n            <br \/>\n            <strong>Guidance<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"border-top: solid black 1pt;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: top\">Oncology\/Immunology consolidated revenues<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$30.2 million<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">$110 \u2013 130 million<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <strong><br \/>\n          <em>Use of Non-GAAP Financial Measures and Reconciliation<\/em><br \/>\n        <\/strong> \u2013 References in this announcement to adjusted Group net cash flows excluding financing activities and financial measures reported at CER are based on non-GAAP financial measures. Please see the \u201cUse of Non-GAAP Financial Measures and Reconciliation\u201d below for further information relevant to the interpretation of these financial measures and reconciliations of these financial measures to the most comparable GAAP measures, respectively.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <em>Conference Call and Audio Webcast Presentation Scheduled Today at 1 p.m. GMT \/ 8 a.m. EST \/ 9 p.m. HKT<\/em><br \/>\n        <\/strong> \u2013 Investors may participate in the call as follows: +44\u00a020\u00a03194\u00a00569 (U.K.) \/ +1\u00a0646\u00a0722\u00a04977 (U.S.) \/ +852 3027\u00a06500 (Hong Kong), or access a <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=HNR67Njsj-Um7_8LuBMv271V6hO2C2KbD_mx-DZQSQ1syiu23BlQUfOGSaLf-ATmPsFERQyoOIGPGZudpg4m_K0x_5FoqGMEE58LTXsqMfLlFUR4jd2npv3GXihxNdH2-eM04FA24zqjL8TDBR1RHXmLtdDB6A0tCzhGHqeJKm7DZKTC_-Y8exZVTXk2jTUFJCox10fLaSSjabzsEocNMx5lIeffeNo1pfBgGiVlu2k=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">live audio webcast<\/a> of the call via HUTCHMED\u2019s website at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=vGnPEwF9iScuapPrrYHBc7vquiASKoBy_8dssHGrqn477T-CxY0d5Y1Vlrfj9En0dYy0kY5MXkjU1iWploS-Yzlbsjfj8wYzR9c3huqmpC0m570GgZPomqdFEcIdAg3Es7DxAl2A48xQPVMs7ZZayg==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">www.hutch-med.com\/event\/<\/a>.<\/p>\n<p align=\"justify\">Additional dial-in numbers are also available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=wvWoD-QhUdtz5IPLLbM6pLKLzx1XfUUX898_9s5STZNA811tNF_ZUG6IMSkvGiHVBaly4aiix1u9KB8geLTXTgdZmuuCv8SIdQKlcCrNjm8s0aENMYU3lMLsokK1pAdS\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">HUTCHMED&#8217;s website<\/a>. Please use participant access code \u201c<strong>38028560#<\/strong>.\u201d<\/p>\n<p align=\"justify\">This announcement in its entirety is available at:\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UjkEC-1YY2y2Os3PD8Vwodmltuco4h0lnkcG7pVxsJaQ7sOZTctCT4h2wTvuHQJv7FqcZNanj_o-n3GvaA12vmBkzKRcZpF484cGitxl7yU8VsPUD8kgK7ffh2aIOmFuOvwXOaQ2r_e7EQrjF-e4rdfwNaZVQWT2C9IBy1KTZnsQvfWa0zlXJo2rRK0DipAGlCW6vxZhTFMkLimZGd2LyMeltqdh8XpBtuSp2AzKfbRbeE2ZHRh4k9_B1JmUthOF\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">http:\/\/ml.globenewswire.com\/Resource\/Download\/693f5edc-0aa1-45cd-b3ab-090bed0e68e3<\/a><\/p>\n<p align=\"justify\">\n        <strong>FINANCIAL STATEMENTS<\/strong>\n      <\/p>\n<p align=\"justify\">HUTCHMED will today file with the U.S. Securities and Exchange Commission its Annual Report on Form 20-F.<\/p>\n<p align=\"justify\">\n        <strong>ANNUAL GENERAL MEETING<\/strong>\n      <\/p>\n<p align=\"justify\">The Annual General Meeting of HUTCHMED will be held on Wednesday, April 28, 2021. Notice of the 2021 Annual General Meeting will be published and issued to shareholders in due course.<\/p>\n<p align=\"justify\">\n        <strong>About HUTCHMED<\/strong>\n      <\/p>\n<p align=\"justify\">HUTCHMED (Nasdaq\/AIM: HCM) is an innovative, commercial-stage, biopharmaceutical company committed, over the past twenty years, to the discovery and global development of targeted therapies and immunotherapies for the treatment of cancer and immunological diseases. It has advanced ten cancer drug candidates from discovery into clinical studies around the world and has an extensive commercial infrastructure in its home market of China. For more information, please visit: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=vGnPEwF9iScuapPrrYHBc3wd4vAONVFoO9VUMCA2SGcnntQmLpTdswtls64JRW_wiKSTPaVrghp-mEkUoeHwSQ==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">www.hutch-med.com<\/a>.<\/p>\n<p align=\"justify\">\n        <strong>CONTACTS<\/strong>\n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Investor Enquiries<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: top\">Mark Lee, Senior Vice President<\/td>\n<td style=\"vertical-align: top\">+852\u00a02121\u00a08200<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: top\">Annie Cheng, Vice President<\/td>\n<td style=\"vertical-align: top\">+1\u00a0(973)\u00a0567\u00a03786<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Media Enquiries<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Americas<\/strong> \u2013 Brad Miles, Solebury Trout<\/td>\n<td style=\"vertical-align: top\">+1\u00a0(917)\u00a0570\u00a07340\u00a0(Mobile) <br \/><a href=\"mailto:bmiles@troutgroup.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">bmiles@troutgroup.com<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Europe <\/strong>\u2013 Ben Atwell \/ Alex Shaw, FTI Consulting<\/td>\n<td style=\"vertical-align: top\">+44\u00a020\u00a03727\u00a01030 \/ +44\u00a07771\u00a0913\u00a0902\u00a0(Mobile) \/ +44\u00a07779\u00a0545\u00a0055\u00a0(Mobile) <br \/><a href=\"mailto:hutchmed@fticonsulting.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">HUTCHMED@fticonsulting.com<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Asia <\/strong>\u2013 Joseph Chi Lo \/ Zhou Yi, Brunswick<\/td>\n<td style=\"vertical-align: top\">+852\u00a09850\u00a05033 (Mobile), <a href=\"mailto:jlo@brunswickgroup.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">jlo@brunswickgroup.com<\/a> \/ <br \/>+852\u00a09783\u00a06894\u00a0(Mobile), <a href=\"mailto:yzhou@brunswickgroup.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">yzhou@brunswickgroup.com<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: top\">\n            <strong>Nominated Advisor<\/strong>\n          <\/td>\n<td style=\"vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;vertical-align: top\">Freddy Crossley \/ Atholl Tweedie, Panmure Gordon (UK)\u00a0Limited<\/td>\n<td style=\"vertical-align: top\">+44\u00a0(20)\u00a07886\u00a02500<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <strong>References<\/strong>\n      <\/p>\n<p align=\"justify\">Unless the context requires otherwise, references in this announcement to the \u201cGroup,\u201d the \u201cCompany,\u201d \u201cHUTCHMED,\u201d \u201cHUTCHMED Group,\u201d \u201cwe,\u201d \u201cus,\u201d and \u201cour,\u201d mean Hutchison China MediTech Limited and its consolidated subsidiaries and joint ventures unless otherwise stated or indicated by context.<\/p>\n<p align=\"justify\">\n        <strong><br \/>\n          <em>Past Performance and Forward-Looking Statements<\/em><br \/>\n        <\/strong>\n      <\/p>\n<p align=\"justify\">\n        <em>The performance and results of operations of the Group contained within this announcement are historical in nature, and past performance is no guarantee of future results of the Group. This announcement contains forward-looking statements within the meaning of the \u201csafe harbor\u201d provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements can be identified by words like \u201cwill,\u201d \u201cexpects,\u201d \u201canticipates,\u201d \u201cfuture,\u201d \u201cintends,\u201d \u201cplans,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cpipeline,\u201d \u201ccould,\u201d \u201cpotential,\u201d \u201cfirst-in-class,\u201d \u201cdesigned to,\u201d \u201cobjective,\u201d \u201cguidance,\u201d \u201cpursue,\u201d or similar terms, or by express or implied discussions regarding potential drug candidates, potential indications for drug candidates or by discussions of strategy, plans, expectations or intentions. You should not place undue reliance on these statements. Such forward-looking statements are based on the current beliefs and expectations of management regarding future events, and are subject to significant known and unknown risks and uncertainties. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those set forth in the forward-looking statements. There can be no guarantee that any of our drug candidates will be approved for sale in any market, or that any approvals which are obtained will be obtained at any particular time, or that any such drug candidates will achieve any particular revenue or net income levels. In particular, management\u2019s expectations could be affected by, among other things: unexpected regulatory actions or delays or government regulation generally; the uncertainties inherent in research and development, including the inability to meet our key study assumptions regarding enrollment rates, timing and availability of subjects meeting a study\u2019s inclusion and exclusion criteria and funding requirements, changes to clinical protocols, unexpected adverse events or safety, quality or manufacturing issues; the inability of a drug candidate to meet the primary or secondary endpoint of a study; the impact of the COVID-19 pandemic or other health crises in China or globally; the inability of a drug candidate to obtain regulatory approval in different jurisdictions or gain commercial acceptance after obtaining regulatory approval; global trends toward health care cost containment, including ongoing pricing pressures; uncertainties regarding actual or potential legal proceedings, including, among others, actual or potential product liability litigation, litigation and investigations regarding sales and marketing practices, intellectual property disputes, and government investigations generally; and general economic and industry conditions, including uncertainties regarding the effects of the persistently weak economic and financial environment in many countries and uncertainties regarding future global exchange rates. For further discussion of these and other risks, see HUTCHMED\u2019s filings with the U.S. Securities and Exchange Commission and on AIM. HUTCHMED is providing the information in this announcement as of this date and does not undertake any obligation to update any forward-looking statements as a result of new information, future events or otherwise.<\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>In addition, this announcement contains statistical data and estimates that HUTCHMED obtained from industry publications and reports generated by third-party market research firms. Although HUTCHMED believes that the publications, reports and surveys are reliable, HUTCHMED has not independently verified the data and cannot guarantee the accuracy or completeness of such data. You are cautioned not to give undue weight to this data. Such data involves risks and uncertainties and are subject to change based on various factors, including those discussed above. <\/em>\n      <\/p>\n<p align=\"justify\">\n        <strong>Inside Information<\/strong>\n      <\/p>\n<p align=\"justify\">This announcement contains inside information for the purposes of Article 7 of Regulation (EU) No 596\/2014.<\/p>\n<p align=\"justify\">\n        <strong>REFERENCES AND ABBREVIATIONS<\/strong>\n      <\/p>\n<p align=\"justify\">\n        <em>1<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Sales of Elunate\u00ae to third parties invoiced by Lilly were $32.7 million (2019: $17.6m) &amp; invoiced by HUTCHMED were $1.0 million (2019: nil).<\/em><br \/>\n        <br \/>\n        <em>2<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Lilly = Eli Lilly and Company<\/em><br \/>\n        <br \/>\n        <em>3<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>NRDL = National Reimbursement Drug List<\/em><br \/>\n        <br \/>\n        <em>4<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>NET = Neuroendocrine tumors<\/em><br \/>\n        <br \/>\n        <em>5<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>NMPA = National Medical Products Administration<\/em><br \/>\n        <br \/>\n        <em>6<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>NDA = New Drug Application<\/em><br \/>\n        <br \/>\n        <em>7<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>MET = Mesenchymal epithelial transition receptor<\/em><br \/>\n        <br \/>\n        <em>8<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>NSCLC = Non-small cell lung cancer<\/em><br \/>\n        <br \/>\n        <em>9<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>IND = Investigational new drug application<\/em><br \/>\n        <br \/>\n        <em>10<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ERK = Extracellular signal-regulated kinase<\/em><br \/>\n        <br \/>\n        <em>11<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>MAPK pathway = RAS-RAF-MEK-ERK signaling cascade<\/em><br \/>\n        <br \/>\n        <em>12<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>FDA = Food and Drug Administration<\/em><br \/>\n        <br \/>\n        <em>13<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>EMA = European Medicines Agency<\/em><br \/>\n        <br \/>\n        <em>14<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>CHMP = Committee for Medicinal Products for Human Use<\/em><br \/>\n        <br \/>\n        <em>15<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>MAA = Marketing Authorisation Application<\/em><br \/>\n        <br \/>\n        <em>16<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>CRC = Colorectal cancer<\/em><br \/>\n        <br \/>\n        <em>17<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>VEGFR = Vascular endothelial growth factor receptor<\/em><br \/>\n        <br \/>\n        <em>18<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>FGFR = Fibroblast growth factor receptor<\/em><br \/>\n        <br \/>\n        <em>19<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>CSF-1R = Colony stimulating factor-1 receptor<\/em><br \/>\n        <br \/>\n        <em>20<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ESMO = European Society for Medical Oncology Annual Congress<\/em><br \/>\n        <br \/>\n        <em>21<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ASCO = American Society of Clinical Oncology Annual Meeting<\/em><br \/>\n        <br \/>\n        <em>22<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>AACR = American Association of Cancer Research Annual Meeting<\/em><br \/>\n        <br \/>\n        <em>23<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Junshi = Shanghai Junshi Biosciences Co. Ltd.<\/em><br \/>\n        <br \/>\n        <em>24<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>PD-1 = Programmed Cell Death Protein-1<\/em><br \/>\n        <br \/>\n        <em>25<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>BeiGene = BeiGene Ltd.<\/em><br \/>\n        <br \/>\n        <em>26<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>IDMC = Independent data monitoring committee<\/em><br \/>\n        <br \/>\n        <em>27<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Innovent = Innovent Biologics, Inc.<\/em><br \/>\n        <br \/>\n        <em>28<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>AstraZeneca = AstraZeneca AB (publ)<\/em><br \/>\n        <br \/>\n        <em>29<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>PD-L1 = Programmed death-ligand 1<\/em><br \/>\n        <br \/>\n        <em>30<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>PRCC = Papillary renal cell carcinoma<\/em><br \/>\n        <br \/>\n        <em>31<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ASCO GU = American Society of Clinical Oncology Genitourinary Symposium<\/em><br \/>\n        <br \/>\n        <em>32<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>WCLC = World Conference on Lung Cancer<\/em><br \/>\n        <br \/>\n        <em>33<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>EGFR = Epidermal growth factor receptor<\/em><br \/>\n        <br \/>\n        <em>34<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>PI3K\u03b4 = Phosphoinositide 3-kinase delta<\/em><br \/>\n        <br \/>\n        <em>35<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ASH = American Society of Hematology Annual Meeting<\/em><br \/>\n        <br \/>\n        <em>36<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Syk = Spleen tyrosine kinase<\/em><br \/>\n        <br \/>\n        <em>37<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ITP = Immune thrombocytopenia purpura<\/em><br \/>\n        <br \/>\n        <em>38<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>IHCC = Intrahepatic cholangiocarcinoma<\/em><br \/>\n        <br \/>\n        <em>39<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>FGFR2 = Fibroblast growth factor receptor 2<\/em><br \/>\n        <br \/>\n        <em>40<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>IDH1\/2 = Isocitrate dehydrogenase 1\/2<\/em><br \/>\n        <br \/>\n        <em>41<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>HBYS = Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Company Limited<\/em><br \/>\n        <br \/>\n        <em>42<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Inmagene = Inmagene Biopharmaceuticals Co. Ltd.<\/em><br \/>\n        <br \/>\n        <em>43<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>R&amp;D = Research and development<\/em><br \/>\n        <br \/>\n        <em>44<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>GAAP = Generally Accepted Accounting Principles<\/em><br \/>\n        <br \/>\n        <em>45<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>General Atlantic = General Atlantic Singapore HCM Pte. Ltd<\/em><br \/>\n        <br \/>\n        <em>46<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>CPP Investments = Canada Pension Plan Investment Board<\/em><br \/>\n        <br \/>\n        <em>47<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>We also report changes in performance at constant exchange rate (\u201cCER\u201d) which is a non-GAAP measure. Please refer to \u201cUse of Non-GAAP Financial Measures and Reconciliation\u201d below for further information relevant to the interpretation of these financial measures and reconciliations of these financial measures to the most comparable GAAP measures.<\/em><br \/>\n        <br \/>\n        <em>48<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>SG&amp;A = Selling, general and administrative<\/em><br \/>\n        <br \/>\n        <em>49<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>Other items = includes other income, income tax expense, equity in earnings of equity investees, net of tax and net income attributable to non-controlling interests<\/em><br \/>\n        <br \/>\n        <em>50<\/em><br \/>\n        <em>\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/em><br \/>\n        <em>ADS = American depositary share<\/em>\n      <\/p>\n<p align=\"center\">\n        <strong>USE OF NON-GAAP FINANCIAL MEASURES AND\u00a0RECONCILIATION<\/strong>\n      <\/p>\n<p align=\"justify\">In addition to financial information prepared in accordance with U.S. GAAP, this announcement also contains certain non-GAAP financial measures based on management\u2019s view of performance including:<\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:9pt;text-align:justify\">Adjusted Group net cash flows excluding financing activities<\/li>\n<li style=\"margin-bottom:9pt;text-align:justify\">CER<\/li>\n<\/ul>\n<p align=\"justify\">Management uses such measures internally for planning and forecasting purposes and to measure the HUTCHMED Group\u2019s overall performance. We believe these adjusted financial measures provide useful and meaningful information to us and investors because they enhance investors\u2019 understanding of the continuing operating performance of our business and facilitate the comparison of performance between past and future periods. These adjusted financial measures are non-GAAP measures and should be considered in addition to, but not as a substitute for, the information prepared in accordance with U.S. GAAP. Other companies may define these measures in different ways.<\/p>\n<p align=\"justify\">\n        <em>Adjusted Group net cash flows excluding financing activities:<\/em> We include the change in short-term investments for the period to the change in cash and cash equivalents for the period, and exclude the net cash (generated from)\/used in financing activities for the period to derive our adjusted Group net cash flows excluding financing activities. We believe the presentation of adjusted Group net cash flows excluding financing activities provides useful and meaningful information about the change in our cash resources excluding those from financing activities which may present significant period-to-period differences.<\/p>\n<p align=\"justify\">\n        <em>CER:<\/em> We remove the effects of currency movements from year-to-year comparisons by retranslating the current year\u2019s performance at previous year\u2019s foreign currency exchange rates. Because we have significant operations in China, the RMB to U.S. dollar exchange rates used for translation may have a significant effect on our reported results. We believe the presentation at CER provides useful and meaningful information because it facilitates year-to-year comparisons of our results and increases the transparency of our underlying performance.<\/p>\n<p align=\"justify\">\n        <strong>Reconciliation of GAAP change in cash and cash equivalents and short-term investments to Adjusted Group net cash flows excluding financing activities:<\/strong>\n      <\/p>\n<table style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"max-width:75%;width:75%;min-width:75%;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">$\u2019millions<\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>2020<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"max-width:11%;width:11%;min-width:11%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>2019<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;border-top: solid black 1pt;vertical-align: top\">Cash and cash equivalents and short-term investments at end of year<\/td>\n<td style=\"border-top: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">435.2<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">217.2<\/td>\n<td style=\"border-top: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;vertical-align: top\">Excludes: Cash and cash equivalents and short-term investments at <br \/>beginning of year<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(217.2<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<td style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(301.0<\/td>\n<td style=\"padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;border-bottom: solid black 1pt;vertical-align: top\">Excludes: Net cash (generated from)\/used in financing activities for the year<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(296.4<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">1.5<\/td>\n<td style=\"border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 10.0px;border-top: solid black 1pt;border-bottom: solid black 1pt;vertical-align: top\">Adjusted Group net cash flows excluding financing activities<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(78.4<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(82.3<\/td>\n<td style=\"border-top: solid black 1pt;border-bottom: solid black 1pt;padding-left: 0;text-align: left;vertical-align: middle;vertical-align: top\">)<\/td>\n<\/tr>\n<\/table>\n<p align=\"justify\">\n        <strong>Reconciliation of GAAP revenues, net income attributable to HUTCHMED from Other Ventures to CER:<\/strong>\n      <\/p>\n<table style=\"border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td rowspan=\"2\" style=\"border-bottom: solid black 1pt;vertical-align: top\">$\u2019millions (except %)<\/p>\n<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Year Ended<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"6\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Change Amount<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"6\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Change %<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>December 31, 2020<\/strong>\n          <\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>December 31, 2019<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Actual<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>CER<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Exchange effect<\/strong>\n          <\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Actual <\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>CER <\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\n            <strong>Exchange effect <\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"max-width:34%;width:34%;min-width:34%;vertical-align: middle\">\n            <strong>Consolidated Revenues <\/strong>\u2014<strong> Other Ventures<\/strong><\/td>\n<td style=\"max-width:8%;width:8%;min-width:8%;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>197.8<\/strong>\n          <\/td>\n<td style=\"max-width:8%;width:8%;min-width:8%;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>178.1<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>19.7 <\/strong>\u00a0<\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>20.5 <\/strong>\u00a0<\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>(0.8<\/strong><br \/>\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"max-width:1%;width:1%;min-width:1%;text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>11<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>11<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"max-width:8%;width:8%;min-width:8%;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">\n            <strong>0<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: middle\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Consolidated net income attributable to HUTCHMED <\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Excluding one-time HBYS land compensation gain <\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;vertical-align: middle\">\n            <strong>\u00a0 Other Ventures<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong> 44.0 <\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong> 41.5 <\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong> 2.5<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong> 3.3<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong> (0.8<\/strong><br \/>\n            <strong>)<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>6<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>8<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">\n            <strong>-2<\/strong><br \/>\n            <strong>%<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;vertical-align: middle\">\u00a0\u00a0\u2014 Consolidated entities<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">2.8<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">2.9<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(0.1)<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">(0.1)<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">-5%<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">-5%<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">0%<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;vertical-align: middle\">\u00a0\u00a0 \u2014 Equity investees<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">41.2<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">38.6<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">2.6<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">3.4<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">(0.8)<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">7%<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">9%<\/td>\n<td colspan=\"2\" style=\"padding-right: 0;text-align: right;vertical-align: middle;vertical-align: bottom\">-2%<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle;text-align: left;padding-left: 20.0px;vertical-align: middle\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: bottom\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"vertical-align: middle\">\n            <strong>Land compensation gain<\/strong>\n          <\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td style=\"border-bottom: solid black 1pt;vertical-align: middle\">\u2014 HBYS<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">28.8<\/td>\n<td style=\"border-bottom: solid black 1pt;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">28.8<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">28.8<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;<\/td>\n<td style=\"text-align: right;vertical-align: middle;vertical-align: top\">\u00a0<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;<\/td>\n<td colspan=\"2\" style=\"border-bottom: solid black 1pt;padding-right: 0;text-align: right;vertical-align: middle;vertical-align: top\">&#8211;<\/td>\n<\/tr>\n<\/table>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE4NDQzMiM0MDQ4Mzk5IzIwOTY3MTU=\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/79f479e9-3589-46e4-9f27-90d97ea73f51\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Company to Host Annual Results Call &amp; Webcast Today at 1 p.m. GMT \/ 8 a.m. EST \/ 9 p.m. HKT HONG KONG and SHANGHAI and FLORHAM PARK, N.J., March 04, 2021 (GLOBE NEWSWIRE) &#8212; Hutchison China MediTech Limited (\u201cHUTCHMED\u201d) (Nasdaq\/AIM: HCM), an innovation-driven, commercial-stage biopharmaceutical company, today reports its audited financial results for the year ended December 31, 2020 and provides updates on key clinical and commercial developments.\u00a0\u00a0 The Company also intends to seek shareholders\u2019 approval to change its name to HUTCHMED (China) Limited at its forthcoming Annual General Meeting. For more information on the new corporate name, see 2020 Full Year Results &amp; Business Updates\u2014VI.\u00a0Evolution of Our Corporate Identity. 2020 FULL YEAR RESULTS &amp; BUSINESS UPDATES \u201cAt the &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-450437","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Company to Host Annual Results Call &amp; Webcast Today at 1 p.m. GMT \/ 8 a.m. EST \/ 9 p.m. HKT HONG KONG and SHANGHAI and FLORHAM PARK, N.J., March 04, 2021 (GLOBE NEWSWIRE) &#8212; Hutchison China MediTech Limited (\u201cHUTCHMED\u201d) (Nasdaq\/AIM: HCM), an innovation-driven, commercial-stage biopharmaceutical company, today reports its audited financial results for the year ended December 31, 2020 and provides updates on key clinical and commercial developments.\u00a0\u00a0 The Company also intends to seek shareholders\u2019 approval to change its name to HUTCHMED (China) Limited at its forthcoming Annual General Meeting. For more information on the new corporate name, see 2020 Full Year Results &amp; Business Updates\u2014VI.\u00a0Evolution of Our Corporate Identity. 2020 FULL YEAR RESULTS &amp; BUSINESS UPDATES \u201cAt the &hellip; Continue reading &quot;Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-03-04T12:03:47+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE4NDQzMiM0MDQ4Mzk5IzIwOTY3MTU=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"26 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity\",\"datePublished\":\"2021-03-04T12:03:47+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/\"},\"wordCount\":5218,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE4NDQzMiM0MDQ4Mzk5IzIwOTY3MTU=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/hutchison-china-meditech-limited-reports-2020-full-year-results-and-provides-business-updates-and-evolves-corporate-identity\\\/\",\"name\":\"Hutchison China MediTech Limited Reports\u00a02020\u00a0Full Year Results and Provides Business\u00a0Updates and Evolves Corporate Identity - 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