{"id":439789,"date":"2021-02-19T07:33:15","date_gmt":"2021-02-19T12:33:15","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=439789"},"modified":"2021-02-19T07:33:15","modified_gmt":"2021-02-19T12:33:15","slug":"bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/","title":{"rendered":"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">SAN FRANCISCO, Feb.  19, 2021  (GLOBE NEWSWIRE) &#8212; BridgeBio\u00a0Pharma, Inc. (Nasdaq: BBIO),\u202fa clinical-stage biopharmaceutical company founded to discover, create, test and deliver meaningful medicines for patients with genetic diseases and cancers with clear genetic drivers,\u202fand\u00a0affiliate\u00a0ML Bio\u00a0Solutions\u00a0today announced\u00a0that\u00a0the\u00a0first patient has been dosed in\u00a0a\u00a0Phase\u00a02\u00a0trial of\u00a0BBP-418 in patients with LGMD2i.\u00a0BridgeBio\u00a0and ML Bio\u2019s BBP-418 is\u00a0the first-ever oral disease-modifying investigational treatment for LGMD2i.\u00a0BBP-418\u00a0was\u00a0granted Orphan Drug Designation for LGMD2i by the US Food and Drug Administration (FDA) in 2019,\u00a0and\u00a0for LGMD by the European Medicines Agency (EMA) in 2020.<\/p>\n<p>LGMD2i\u00a0is an\u00a0inherited\u00a0recessive\u00a0muscular dystrophy caused by\u00a0mutation of\u00a0fukutin-related protein (FKRP).\u00a0FKRP is an enzyme that adds a sugar molecule\u00a0to a critical\u00a0muscle cell\u00a0structural protein\u00a0called alpha-dystroglycan\u00a0(\u03b1DG). Due to defective FKRP enzyme function, muscle cells of patients affected by LGMD2i\u00a0lack the structural integrity that is provided by fully glycosylated\u00a0\u03b1DG protein. This leads to chronic muscle injury and loss, muscle weakness and disability.\u00a0Many affected\u00a0patients\u00a0ultimately\u00a0lose their ability to walk,\u00a0and some\u00a0develop a need for ventilatory support or\u00a0die from heart failure.\u00a0Currently,\u00a0there are no disease-modifying therapies for\u00a0people with\u00a0LGMD2i.\u00a0<\/p>\n<p>BBP-418 is designed to bypass the metabolic defect in LGMD2i\u00a0by\u00a0providing the\u00a0FKRP\u00a0enzyme\u00a0with precursor sugar molecules\u00a0that\u00a0supplement\u00a0the\u00a0body\u2019s\u00a0natural sugars\u00a0used by FKRP\u00a0to glycosylate the\u00a0\u03b1DG\u00a0protein\u00a0on muscle cells. BBP-418 represents a novel substrate\u00a0rescue\u00a0approach\u00a0with the potential to improve muscle strength and function.\u00a0<\/p>\n<p>The Phase 2 trial is expected to enroll up to 16 patients with a genetically-confirmed diagnosis of LGMD2i. In addition to safety, key efficacy measurements include changes in muscle \u03b1DG glycosylation levels, and changes in functional measures including 10 meter walk and North Star for Dysferlinopathy (NSAD).<\/p>\n<p>\u201cThe start of our Phase 2 trial is a key milestone in our effort to develop a safe and efficacious therapy for patients with\u00a0LGMD2i\u00a0who lack treatment options,\u201d said\u00a0Dr.\u00a0Douglas Sproule, M.D. M.Sc.,\u00a0Chief\u00a0Medical\u00a0Officer\u00a0of ML Bio\u00a0Solutions.\u00a0\u201cThis trial launch is an outgrowth of our strong partnership with the GRASP-LGMD consortium based at Virginia Commonwealth University, where we are currently enrolling a lead-in study to define\u00a0LGMD2i-specific biomarkers and functional endpoints. Our hope is that the ongoing lead-in study, together with early data from our Phase 2 trial, will hasten the successful execution of a future registrational trial and ultimately advance a meaningful medicine for patients in need.\u201d\u00a0<\/p>\n<p>\u201cWe are pleased to\u00a0continue\u00a0our\u00a0collaboration with\u00a0ML Bio Solutions\u00a0on the lead-in\u00a0study that is currently\u00a0enrolling\u00a0and\u00a0look forward to\u00a0further\u00a0extending it\u00a0by\u00a0launching\u00a0the first-in-patient\u00a0treatment study for BBP-418.\u00a0Our\u00a0clinical\u00a0partnership\u00a0is seeking to\u00a0validate the biomarker assays and\u00a0establish the registrational\u00a0clinical outcome measures that are needed to bring BBP-418 to LGMD2i\u00a0patients,\u201d said Dr. Nicholas Johnson M.D.\u00a0M.S.C.I., Associate Professor of Neurology and Chair of Research at Virginia Commonwealth University and Director of the GRASP-LGMD\u00a0consortium.\u00a0\u00a0<\/p>\n<p>\n        <strong>About\u00a0GRASP-LGMD (Genetic Resolution and Assessments Solving Phenotypes in LGMD)\u00a0Consortium\u00a0<\/strong>\u00a0<br \/>The GRASP-LGMD\u00a0consortium\u00a0assembles\u00a0an international\u00a0team of neuromuscular specialists, basic scientists, physical therapists, geneticists, informaticians, and patient advocates to address issues related\u00a0to:\u00a0diagnostics; outcome measure development, patient engagement; and therapeutic development, to advance the\u00a0state of LGMD research and readiness to support translation of science into therapeutic development.\u00a0<strong>\u00a0<\/strong>For more information visit:\u00a0<strong>http:\/\/www.grasp-lgmd.org<\/strong>\u00a0<\/p>\n<p>\n        <strong>About ML Bio Solutions<\/strong>\u00a0<br \/>ML Bio Solutions,\u00a0an\u00a0affiliate\u00a0of\u00a0BridgeBio\u00a0Pharma\u00a0based in a Charlotte, NC, is a biotechnology company focused on developing a small molecule as an oral substrate supplementation therapy for LGMD2i. ML Bio Solutions is led by a team of veteran biotechnology executives, and together with patients and physicians, aims to bring safe, effective treatments to market as quickly as possible.\u00a0For more information, visit\u00a0<strong><u>mlbiosolutions.com.<\/u><\/strong>\u00a0<\/p>\n<p>\n        <strong>About\u00a0BridgeBio\u00a0Pharma<\/strong>\u00a0<br \/>BridgeBio\u00a0is a team of experienced drug discoverers, developers and innovators working to create life-altering medicines that target well-characterized genetic diseases at their source.\u00a0BridgeBio\u00a0was founded in 2015 to identify and advance transformative medicines to treat patients who suffer from Mendelian diseases, which are diseases that arise from defects in a single gene, and cancers with clear genetic drivers.\u00a0BridgeBio\u2019s\u00a0pipeline of over 20 development programs includes product candidates ranging from early discovery to late-stage development. For more information, visit\u202f<strong>bridgebio.com<\/strong>.\u00a0<\/p>\n<p>\n        <strong>BridgeBio\u00a0Pharma Forward-Looking Statements<\/strong>\u00a0<br \/>This press release contains forward-looking statements. Statements we make in this press release may include statements that are not historical facts and are considered forward-looking within the meaning of Section 27A of the Securities Act of 1933, as amended (the \u201cSecurities Act\u201d), and Section 21E of the Securities Exchange Act of 1934, as amended (the \u201cExchange Act\u201d), which are usually identified by the use of words such as \u201canticipates,\u201d \u201cbelieves,\u201d \u201cestimates,\u201d \u201cexpects,\u201d \u201cintends,\u201d \u201cmay,\u201d \u201cplans,\u201d \u201cprojects,\u201d \u201cseeks,\u201d \u201cshould,\u201d \u201cwill,\u201d and variations of such words or similar expressions.\u202f We intend these forward-looking statements to be covered by the safe harbor provisions for forward-looking statements contained in Section 27A of the Securities Act and Section 21E of the Exchange Act and are making this statement for purposes of complying with those safe harbor provisions.\u202f These forward-looking statements, including statements relating to\u00a0the timing and success of ML Bio\u00a0Solutions\u2019 Phase 2 clinical trial of BBP-418\u00a0for the treatment of LGMD2i,\u00a0expectations, plans and prospects regarding ML Bio\u00a0Solutions\u2019 regulatory approval process for BBP-418,\u00a0the ability of BBP-418 to treat LGMD2i\u00a0in humans,\u00a0and\u00a0the timing and success of\u00a0initial top-line Phase 2 date of BBP-418, reflect our current views about our plans, intentions, expectations, strategies and prospects, which are based on the information currently available to us and on assumptions we have made. Although we believe that our plans, intentions, expectations, strategies and prospects as reflected in or suggested by those forward-looking statements are reasonable, we can give no assurance that the plans, intentions, expectations or strategies will be attained or achieved.\u202f Furthermore, actual results may differ materially from those described in the forward-looking statements and will be affected by\u00a0a number of\u00a0risks, uncertainties and assumptions, including, but not limited to,\u00a0ML\u00a0Bio\u00a0Solutions\u2019\u00a0ability\u00a0to continue and complete its Phase 2 clinical trial of BBP-418\u00a0for the treatment of LDMD2i,\u00a0the continuing success of ML Bio\u00a0Solutions\u2019 collaboration with the GRASP-LGMD\u00a0consortium\u00a0based at Virginia Commonwealth University,\u00a0past data\u00a0from preclinical studies\u00a0not being indicative of future data\u00a0from clinical trials,\u00a0ML Bio\u00a0Solutions\u2019\u00a0ability to advance\u00a0BBP-418\u00a0in clinical development according to its plans, the ability of BBP-418 to treat LGMD2i, as well as those risks set forth in the Risk Factors section of\u00a0BridgeBio\u00a0Pharma\u2019s most recent Quarterly Report on Form 10-Q and\u00a0BridgeBio\u00a0Pharma\u2019s other SEC filings. Moreover,\u00a0ML BioSolutions\u00a0operates in a very competitive and rapidly changing environment in which new risks emerge from time to time. Except as required by applicable law, we assume no obligation to update publicly any forward-looking statements, whether as a result of new information, future events or otherwise.\u00a0<\/p>\n<p>Contact:\u00a0<br \/>Grace Rauh,\u00a0BridgeBio\u00a0Pharma\u00a0<br \/>grace.rauh@bridgebio.com\u00a0<br \/>917-232-5478\u00a0<\/p>\n<p>Source:\u00a0BridgeBio\u00a0Pharma\u00a0\u00a0<\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE1NjA0NCMzOTg0OTEwIzIxNTY5MjY=\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/4f90ec65-66fc-4a36-81c0-dc5ad4e961a2\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>SAN FRANCISCO, Feb. 19, 2021 (GLOBE NEWSWIRE) &#8212; BridgeBio\u00a0Pharma, Inc. (Nasdaq: BBIO),\u202fa clinical-stage biopharmaceutical company founded to discover, create, test and deliver meaningful medicines for patients with genetic diseases and cancers with clear genetic drivers,\u202fand\u00a0affiliate\u00a0ML Bio\u00a0Solutions\u00a0today announced\u00a0that\u00a0the\u00a0first patient has been dosed in\u00a0a\u00a0Phase\u00a02\u00a0trial of\u00a0BBP-418 in patients with LGMD2i.\u00a0BridgeBio\u00a0and ML Bio\u2019s BBP-418 is\u00a0the first-ever oral disease-modifying investigational treatment for LGMD2i.\u00a0BBP-418\u00a0was\u00a0granted Orphan Drug Designation for LGMD2i by the US Food and Drug Administration (FDA) in 2019,\u00a0and\u00a0for LGMD by the European Medicines Agency (EMA) in 2020. LGMD2i\u00a0is an\u00a0inherited\u00a0recessive\u00a0muscular dystrophy caused by\u00a0mutation of\u00a0fukutin-related protein (FKRP).\u00a0FKRP is an enzyme that adds a sugar molecule\u00a0to a critical\u00a0muscle cell\u00a0structural protein\u00a0called alpha-dystroglycan\u00a0(\u03b1DG). Due to defective FKRP enzyme function, muscle cells of patients affected by LGMD2i\u00a0lack the structural integrity that &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-439789","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i) - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i) - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"SAN FRANCISCO, Feb. 19, 2021 (GLOBE NEWSWIRE) &#8212; BridgeBio\u00a0Pharma, Inc. (Nasdaq: BBIO),\u202fa clinical-stage biopharmaceutical company founded to discover, create, test and deliver meaningful medicines for patients with genetic diseases and cancers with clear genetic drivers,\u202fand\u00a0affiliate\u00a0ML Bio\u00a0Solutions\u00a0today announced\u00a0that\u00a0the\u00a0first patient has been dosed in\u00a0a\u00a0Phase\u00a02\u00a0trial of\u00a0BBP-418 in patients with LGMD2i.\u00a0BridgeBio\u00a0and ML Bio\u2019s BBP-418 is\u00a0the first-ever oral disease-modifying investigational treatment for LGMD2i.\u00a0BBP-418\u00a0was\u00a0granted Orphan Drug Designation for LGMD2i by the US Food and Drug Administration (FDA) in 2019,\u00a0and\u00a0for LGMD by the European Medicines Agency (EMA) in 2020. LGMD2i\u00a0is an\u00a0inherited\u00a0recessive\u00a0muscular dystrophy caused by\u00a0mutation of\u00a0fukutin-related protein (FKRP).\u00a0FKRP is an enzyme that adds a sugar molecule\u00a0to a critical\u00a0muscle cell\u00a0structural protein\u00a0called alpha-dystroglycan\u00a0(\u03b1DG). Due to defective FKRP enzyme function, muscle cells of patients affected by LGMD2i\u00a0lack the structural integrity that &hellip; Continue reading &quot;BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-19T12:33:15+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE1NjA0NCMzOTg0OTEwIzIxNTY5MjY=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)\",\"datePublished\":\"2021-02-19T12:33:15+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/\"},\"wordCount\":1221,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE1NjA0NCMzOTg0OTEwIzIxNTY5MjY=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\\\/\",\"name\":\"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i) - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/","og_locale":"en_US","og_type":"article","og_title":"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i) - Market Newsdesk","og_description":"SAN FRANCISCO, Feb. 19, 2021 (GLOBE NEWSWIRE) &#8212; BridgeBio\u00a0Pharma, Inc. (Nasdaq: BBIO),\u202fa clinical-stage biopharmaceutical company founded to discover, create, test and deliver meaningful medicines for patients with genetic diseases and cancers with clear genetic drivers,\u202fand\u00a0affiliate\u00a0ML Bio\u00a0Solutions\u00a0today announced\u00a0that\u00a0the\u00a0first patient has been dosed in\u00a0a\u00a0Phase\u00a02\u00a0trial of\u00a0BBP-418 in patients with LGMD2i.\u00a0BridgeBio\u00a0and ML Bio\u2019s BBP-418 is\u00a0the first-ever oral disease-modifying investigational treatment for LGMD2i.\u00a0BBP-418\u00a0was\u00a0granted Orphan Drug Designation for LGMD2i by the US Food and Drug Administration (FDA) in 2019,\u00a0and\u00a0for LGMD by the European Medicines Agency (EMA) in 2020. LGMD2i\u00a0is an\u00a0inherited\u00a0recessive\u00a0muscular dystrophy caused by\u00a0mutation of\u00a0fukutin-related protein (FKRP).\u00a0FKRP is an enzyme that adds a sugar molecule\u00a0to a critical\u00a0muscle cell\u00a0structural protein\u00a0called alpha-dystroglycan\u00a0(\u03b1DG). Due to defective FKRP enzyme function, muscle cells of patients affected by LGMD2i\u00a0lack the structural integrity that &hellip; Continue reading \"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/","og_site_name":"Market Newsdesk","article_published_time":"2021-02-19T12:33:15+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE1NjA0NCMzOTg0OTEwIzIxNTY5MjY=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"6 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i)","datePublished":"2021-02-19T12:33:15+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/"},"wordCount":1221,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE1NjA0NCMzOTg0OTEwIzIxNTY5MjY=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/bridgebio-pharma-and-affiliate-ml-bio-solutions-announce-dosing-of-first-patient-in-phase-2-trial-of-bbp-418-in-limb-girdle-muscular-dystrophy-type-2i-lgmd2i\/","name":"BridgeBio Pharma and Affiliate ML Bio Solutions Announce Dosing of First Patient in Phase 2 Trial of BBP-418 in Limb Girdle Muscular Dystrophy Type 2i (LGMD2i) - 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