{"id":430570,"date":"2021-02-08T08:33:30","date_gmt":"2021-02-08T13:33:30","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=430570"},"modified":"2021-02-08T08:33:30","modified_gmt":"2021-02-08T13:33:30","slug":"cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/","title":{"rendered":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"justify\">AUSTIN, Texas, Feb.  08, 2021  (GLOBE NEWSWIRE) &#8212; Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company developing product candidates for Alzheimer\u2019s disease, today announced significant program progress and expected milestones for 2021.<\/p>\n<p align=\"justify\">\u201cWe started 2021 with tremendous momentum, led by results of a 6-month interim analysis from an open-label study of simufilam, our drug candidate for Alzheimer\u2019s disease,\u201d said Remi Barbier, President &amp; CEO. \u201cI believe the rest of the year may be equally exciting.\u201d<\/p>\n<p align=\"justify\">Cassava Sciences\u2019 strategic focus for 2021 is to advance simufilam in a Phase 3 clinical program in Alzheimer\u2019s disease, to expand drug manufacturing capabilities in support of the clinical program, and to continue to lead the Company to deliver the full potential of its product portfolio.<\/p>\n<p align=\"justify\">\n        <strong>Cassava Sciences\u2019 2021 Scientific and Clinical Outlook<\/strong><br \/>\n        <br \/>Cassava Sciences\u2019 product portfolio includes a small molecule drug for the treatment of Alzheimer\u2019s disease, called simufilam, and an investigational blood-based diagnostic to detect and monitor the progression of Alzheimer\u2019s disease, called SavaDx.<\/p>\n<p align=\"justify\">Expected progress and key milestones in 2021 across Cassava Sciences\u2019 product portfolio are summarized below.<\/p>\n<ul type=\"square\">\n<li style=\"text-align:justify\">Based on recent positive clinical results and inbound demand from clinical sites, patients, and their caregivers, Cassava Sciences plans to expand the size of the ongoing open-label study of simufilam. The target enrollment will be increased by up to 50 additional patients with mild-to-moderate Alzheimer\u2019s disease, for a total target enrollment of up to 150 patients.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences has enrolled approximately 80 patients in the open-label study to date. To accommodate increased enrollment, the Company plans to open new clinical sites across the U.S. and Canada.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences expects to announce results of a second interim analysis of the ongoing open-label study when approximately 50 patients complete 12 months of drug treatment. This second interim analysis is expected to include clinical data around long-term safety, cognition and Alzheimer\u2019s-related behavior.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences plans to initiate a 6-month, double-blind, randomized, placebo-controlled study in patients with Alzheimer\u2019s disease who complete at least one year of open-label treatment with simufilam. This is a <em>Cognition Maintenance Study<\/em> (CMS), in which patients who complete one year of open-label treatment will subsequently be randomized (1:1) to simufilam or placebo for six months. The CMS is designed to compare simufilam\u2019s effects on cognition and behavior in patients who continue with drug treatment versus those who discontinue drug treatment. For ethical and other reasons, patients who successfully complete the six-month CMS will have the option to receive open-label simufilam.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences\u2019 clinical and regulatory strategy for simufilam is progressing as planned. In January 2021, the Company concluded a successful End-of-phase 2 (EOP2) meeting with the U.S Food and Drug Administration (FDA). The purpose of the EOP2 was to gain general agreement around a Phase 3 program to treat Alzheimer\u2019s disease dementia.\n<\/li>\n<\/ul>\n<ul type=\"square\">\n<li style=\"text-align:justify\">As a result of the EOP2 meeting, Cassava Sciences believes its clinical program for simufilam is green-lighted to commence a large, Phase 3 clinical program in patients with Alzheimer\u2019s disease, pending official FDA meeting minutes of the EOP2 meeting.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences plans to initiate a Phase 3 program of simufilam in Alzheimer\u2019s disease in the second half of 2021.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences\u2019 Phase 3 program for simufilam consists of two large, double-blind, randomized, placebo-controlled studies of simufilam in patients with mild-to-moderate Alzheimer\u2019s disease dementia. The Company expects to announce details of its Phase 3 program in Q1 2021, pending official FDA meeting minutes of the EOP2 meeting.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences\u2019 first Phase 3 study will evaluate disease-modifying effects in Alzheimer\u2019s disease patients over 18 months. The goal of this study is to show a slower rate of decline in cognition and daily function in patients treated with simufilam, compared to patients treated with placebo.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences\u2019 second Phase 3 study will evaluate symptomatic improvement in Alzheimer\u2019s disease patients over 6 months. The goal of this study is to show improvement in cognition and daily function in patients treated with simufilam, compared to patients treated with placebo.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences believes its manufacturing strategy is on-track to ensure sufficient drug supply for a Phase 3 program, including both drug substance (i.e., active ingredient) and drug product (i.e., oral tablets).\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences expects to conclude a long-term, commercial drug supply agreement for simufilam with a contract manufacturing organization. The goal is to ensure the integrity of the drug supply chain on a worldwide basis, in compliance with FDA standards.\n<\/li>\n<\/ul>\n<ul type=\"square\">\n<li style=\"text-align:justify\">Cassava Sciences expects to initiate a validation study with SavaDx, its investigational diagnostic for the detection of Alzheimer\u2019s disease.\n<\/li>\n<li style=\"text-align:justify\">Cassava Sciences is in discussions with scientific and clinical advisors about potentially expanding therapeutic indications for simufilam outside of Alzheimer\u2019s disease, but still within neurodegenerative conditions.\n<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Other Expected Milestones and Announcements for 2021<\/strong>\n      <\/p>\n<ul type=\"square\">\n<li style=\"text-align:justify\">Cassava Sciences expects to announce publication of Phase 2b results in a peer-reviewed technical journal.\n<\/li>\n<li style=\"text-align:justify\">Net cash use for full-year 2021 is expected to be in the range of $20 to $25 million, depending on enrollment rates in its clinical programs and other factors. On December 31, 2020, unaudited cash and cash equivalents were approximately $93 million.<\/li>\n<\/ul>\n<p align=\"justify\">\n        <strong>Slide Deck<\/strong><br \/>\n        <br \/>A copy of Cassava Sciences\u2019 latest corporate presentation is available on its website <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TK9sLZzEVqGSyCw_33H65pKu8BXHuxgJtZKTGnrgzSl2gFwIDHi4EjXd-cfUtpMEJUsfUPI58t-jcefZjMnMsWFTyO_opeNn6gcWim_dpodWG3U3IW4RlrnNzSew4A5l\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">https:\/\/www.CassavaSciences.com<\/a>, under the Investors\/Presentations page.<\/p>\n<p align=\"justify\">\n        <strong>About Alzheimer&#8217;s Disease <\/strong><br \/>\n        <br \/>Alzheimer\u2019s disease is a progressive brain disorder that destroys memory and thinking skills. Currently, there are no drug therapies to halt Alzheimer\u2019s disease, much less reverse its course. In the U.S. alone, approximately 5.8 million people are currently living with Alzheimer\u2019s disease, and approximately 487,000 people age 65 or older developed Alzheimer\u2019s in 2019.<sup>1<\/sup> The number of people living with Alzheimer\u2019s disease is expected to grow dramatically in the years ahead, resulting in a growing social and economic burden.<sup>2<\/sup><\/p>\n<p align=\"justify\">\n        <strong>About Simufilam<\/strong><br \/>\n        <br \/>Simufilam is a proprietary, small molecule (oral) drug that restores the normal shape and function of altered filamin A (FLNA), a scaffolding protein, in the brain. Altered FLNA in the brain disrupts the normal function of neurons, leading to Alzheimer\u2019s pathology, neurodegeneration and neuroinflammation. The underlying science for simufilam is published in peer-reviewed journals, including <em>Journal of Neuroscience<\/em>, <em>Neurobiology of Aging<\/em>, <em>Journal of Biological Chemistry, Neuroimmunology and Neuroinflammation <\/em>and<em> Journal of Prevention of Alzheimer\u2019s Disease. <\/em><\/p>\n<p align=\"justify\">Cassava Sciences is also developing an investigational diagnostic, called SavaDx, to detect Alzheimer\u2019s disease with a simple blood test.<br \/>Simufilam and SavaDx were both developed in-house. Both product candidates are substantially funded by peer-review research grant awards from the National Institutes of Health (NIH). Cassava Sciences owns worldwide development and commercial rights to its research programs in Alzheimer\u2019s disease, and related technologies, without royalty obligations to any third party.<\/p>\n<p align=\"justify\">\n        <strong>About Cassava Sciences, Inc.<\/strong><br \/>\n        <br \/>Cassava Sciences\u2019 mission is to discover and develop innovations for chronic, neurodegenerative conditions. Over the past 10 years, Cassava Sciences has combined state-of-the-art technology with new insights in neurobiology to develop novel solutions for Alzheimer\u2019s disease. For more information, please visit: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TK9sLZzEVqGSyCw_33H65pKu8BXHuxgJtZKTGnrgzSm0IXtORwwR8Dad1vPPs6hb4LJj7K4CEYjs2fSHdZJpj9xXW8NujvtB7WBs8MLfwjWbbsaRyRyCEa3zdevEX6sA\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">https:\/\/www.CassavaSciences.com<\/a><\/p>\n<p align=\"justify\">\n        <strong>For More Information Contact:<\/strong><br \/>\n        <br \/>Eric Schoen, Chief Financial Officer<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=J7zYlTB1pIau3MSvIQmcw3rj3NwUQbDIDGewcDoQPUH7wYL3zH69nk4fN04608GWfN4noZRGfQGXYO6T74uOZ0CHSvwXe3_Lya-BFeSGoEPbViEI1g3itY42i0rM1Uuj\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">eschoen@CassavaSciences.com<\/a><br \/>(512) 501-2450<\/p>\n<p align=\"center\">\n        <em>Cassava Sciences\u2019 open-label study of simufilam in Alzheimer\u2019s disease is funded by clinical research grant #AG065152 from the National Institutes of Health (NIH\/NIA). <\/em>\n      <\/p>\n<p align=\"center\">\n        <em>The content of this press release is solely the responsibility of Cassava Sciences and does not necessarily represent the official views of the NIH\/NIA. <\/em>\n      <\/p>\n<p align=\"justify\">\n        <strong>Cassava Sciences Safe Harbor<\/strong><br \/>\n        <br \/>\n        <em>This news release contains forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, relating to: our strategy and plans; the treatment of Alzheimer\u2019s disease; <\/em><br \/>\n        <em>the status of current and future clinical studies with simufilam, including the interpretation of an interim analysis of open-label study results; planned enrollment and other changes to the open-label program; our intention to initiate a Phase 3 clinical program with simufilam in 2<\/em><br \/>\n        <sup>nd<\/sup><br \/>\n        <em> half 2021; results of our EOP2 meeting with FDA and the timing of further announcements; our ability to manufacture drug supply for a Phase 3 program and to enter into a long-term commercial drug supply agreement; <\/em><br \/>\n        <em>the timing of validation studies with SavaDx; our ability to expand therapeutic indications for simufilam outside of Alzheimer\u2019s disease;<\/em><br \/>\n        <em>expected cash use in future periods;<\/em><br \/>\n        <em>plans to publish results of a Phase 2b study in a peer-reviewed journal; verbal commentaries made by our employees; and potential benefits, if any, of the our product candidates. <\/em><br \/>\n        <em>These statements may be identified by words such as \u201cmay,\u201d \u201canticipate,\u201d \u201cbelieve,\u201d \u201ccould,\u201d \u201cexpect,\u201d \u201cforecast,\u201d \u201cintend,\u201d \u201cplan,\u201d \u201cpossible,\u201d \u201cpotential,\u201d and other words and terms of similar meaning. Drug development and commercialization involve a high degree of risk, and only a small number of research and development programs result in commercialization of a product. Our clinical results from earlier-stage clinical trials may not be indicative of full results or results from later-stage or larger scale clinical trials and do not ensure regulatory approval. You should not place undue reliance on these statements or any scientific data we present or publish.<\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>Such statements are based largely on our current expectations and projections about future events. Such statements speak only as of the date of this news release and are subject to a number of risks, uncertainties and assumptions, including, but not limited to, those risks relating to the ability to conduct or complete clinical studies on expected timelines, to demonstrate the specificity, safety, efficacy or potential health benefits of our product candidates, the severity and duration of health care precautions given the COVID-19 pandemic, any unanticipated impacts of the pandemic on our business operations, and including those described in the section entitled \u201cRisk Factors\u201d in our Annual Report on Form 10-K for the year ended December 31, 2019 and future reports to be filed with the SEC. <\/em><br \/>\n        <em>The foregoing sets forth many, but not all, of the factors that could cause actual results to differ from expectations in any forward-looking statement. <\/em><br \/>\n        <em>In light of these risks, uncertainties and assumptions, the forward-looking statements and events discussed in this news release are inherently uncertain and may not occur, and actual results could differ materially and adversely from those anticipated or implied in the forward-looking statements. Accordingly, you should not rely upon forward-looking statements as predictions of future events. Except as required by law, we disclaim any intention or responsibility for updating or revising any forward-looking statements contained in this news release.<\/em><br \/>\n        <em>\u00a0<\/em><br \/>\n        <em>For further information regarding these and other risks related to our business, investors should consult our filings with the SEC, which are available on the SEC&#8217;s website at <\/em><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=pIphCzj5yvVQ7cbV-DmUQJBSLc3RLr8LhHuj-RFMFuFTyZ3qBiqjscW6xKzm9Zeep4YVZypnkArqve2Rz7bzCd5qiUyijMjMs4l_T414mCf_iZ1cYFtM4R58O3_7qlTZQa3oFUeUPK9ToxEmo7s3fco-pp3lo-kMt9fUB4ChmAdCsgNOOVxJa-LxF90-kPWm_OE8QK2fQSwHc69ek_JLbK6Hs3JfEjeLgc4UiM-T9GI=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\"><br \/>\n          <em><br \/>\n            <u>www.sec.gov<\/u><br \/>\n          <\/em><br \/>\n        <\/a><br \/>\n        <em>.<\/em>\n      <\/p>\n<p>\n        <sup><br \/>\n          <em>4, 5<\/em><br \/>\n        <\/sup><br \/>\n        <em> Source: Alzheimer\u2019s Association. <\/em>Disease Facts and Figures<em>. <\/em><em><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TK9sLZzEVqGSyCw_33H65nfYBxdNPW6PGk4mDM4XLDf_mC0ASdoeTXfdsUhoWTkTZOgL0sfOMJzXUE7ZBRs73BxLMS66ld8TlKUAeJPaf-5SCJM1V1Joiem83B50KEjIzT5UR5M9hGBTtEouaJLckeNoX9zQZVoZYEdE5jFvM8nXjBy-SGKbeqtgNSAljpA6CnhVyhLNuuYeMkHBz2EgXvJyQ877QjNx_GgGSxnm_DI=\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">https:\/\/www.alz.org\/media\/documents\/alzheimers-facts-and-figures-2019-r.pdf<\/a><\/em><\/p>\n<\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/21328a70-5163-4f02-823f-bc837ec5aca5\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>AUSTIN, Texas, Feb. 08, 2021 (GLOBE NEWSWIRE) &#8212; Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company developing product candidates for Alzheimer\u2019s disease, today announced significant program progress and expected milestones for 2021. \u201cWe started 2021 with tremendous momentum, led by results of a 6-month interim analysis from an open-label study of simufilam, our drug candidate for Alzheimer\u2019s disease,\u201d said Remi Barbier, President &amp; CEO. \u201cI believe the rest of the year may be equally exciting.\u201d Cassava Sciences\u2019 strategic focus for 2021 is to advance simufilam in a Phase 3 clinical program in Alzheimer\u2019s disease, to expand drug manufacturing capabilities in support of the clinical program, and to continue to lead the Company to deliver the full potential of its &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-430570","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"AUSTIN, Texas, Feb. 08, 2021 (GLOBE NEWSWIRE) &#8212; Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company developing product candidates for Alzheimer\u2019s disease, today announced significant program progress and expected milestones for 2021. \u201cWe started 2021 with tremendous momentum, led by results of a 6-month interim analysis from an open-label study of simufilam, our drug candidate for Alzheimer\u2019s disease,\u201d said Remi Barbier, President &amp; CEO. \u201cI believe the rest of the year may be equally exciting.\u201d Cassava Sciences\u2019 strategic focus for 2021 is to advance simufilam in a Phase 3 clinical program in Alzheimer\u2019s disease, to expand drug manufacturing capabilities in support of the clinical program, and to continue to lead the Company to deliver the full potential of its &hellip; Continue reading &quot;Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-02-08T13:33:30+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease\",\"datePublished\":\"2021-02-08T13:33:30+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/\"},\"wordCount\":1750,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/\",\"name\":\"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\",\"datePublished\":\"2021-02-08T13:33:30+00:00\",\"author\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\",\"contentUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#website\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/\",\"name\":\"Market Newsdesk\",\"description\":\"Latest Business News in Real Time\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\",\"name\":\"Newsdesk\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g\",\"caption\":\"Newsdesk\"},\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/author\\\/newsdesk\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/","og_locale":"en_US","og_type":"article","og_title":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk","og_description":"AUSTIN, Texas, Feb. 08, 2021 (GLOBE NEWSWIRE) &#8212; Cassava Sciences, Inc. (Nasdaq: SAVA), a clinical-stage biotechnology company developing product candidates for Alzheimer\u2019s disease, today announced significant program progress and expected milestones for 2021. \u201cWe started 2021 with tremendous momentum, led by results of a 6-month interim analysis from an open-label study of simufilam, our drug candidate for Alzheimer\u2019s disease,\u201d said Remi Barbier, President &amp; CEO. \u201cI believe the rest of the year may be equally exciting.\u201d Cassava Sciences\u2019 strategic focus for 2021 is to advance simufilam in a Phase 3 clinical program in Alzheimer\u2019s disease, to expand drug manufacturing capabilities in support of the clinical program, and to continue to lead the Company to deliver the full potential of its &hellip; Continue reading \"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/","og_site_name":"Market Newsdesk","article_published_time":"2021-02-08T13:33:30+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"9 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease","datePublished":"2021-02-08T13:33:30+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/"},"wordCount":1750,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/","name":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease - Market Newsdesk","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#primaryimage"},"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=","datePublished":"2021-02-08T13:33:30+00:00","author":{"@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"breadcrumb":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#primaryimage","url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI=","contentUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODE0ODYyOCMzOTY0NjE1IzIwMjc4MTI="},{"@type":"BreadcrumbList","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/cassava-sciences-announces-significant-program-progress-and-expected-key-milestones-in-2021-for-its-clinical-program-in-alzheimers-disease\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.marketnewsdesk.com\/"},{"@type":"ListItem","position":2,"name":"Cassava Sciences Announces Significant Program Progress and Expected Key Milestones in 2021 for Its Clinical Program in Alzheimer\u2019s Disease"}]},{"@type":"WebSite","@id":"https:\/\/www.marketnewsdesk.com\/#website","url":"https:\/\/www.marketnewsdesk.com\/","name":"Market Newsdesk","description":"Latest Business News in Real Time","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.marketnewsdesk.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979","name":"Newsdesk","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/a0d0bd5b0f0ca12a265a459b13169dac35f33776d8501eda5e68844a366f2f46?s=96&d=mm&r=g","caption":"Newsdesk"},"url":"https:\/\/www.marketnewsdesk.com\/index.php\/author\/newsdesk\/"}]}},"_links":{"self":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/430570","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/comments?post=430570"}],"version-history":[{"count":0,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/posts\/430570\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/media?parent=430570"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/categories?post=430570"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.marketnewsdesk.com\/index.php\/wp-json\/wp\/v2\/tags?post=430570"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}