{"id":416940,"date":"2021-01-19T09:33:23","date_gmt":"2021-01-19T14:33:23","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=416940"},"modified":"2021-01-19T09:33:23","modified_gmt":"2021-01-19T14:33:23","slug":"therapeutic-solutions-international-reports-successful-treatment-of-breast-cancer-using-stemvacs-cellular-immunotherapy","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/therapeutic-solutions-international-reports-successful-treatment-of-breast-cancer-using-stemvacs-cellular-immunotherapy\/","title":{"rendered":"Therapeutic Solutions International Reports Successful Treatment of Breast Cancer using StemVacs\u2122 Cellular Immunotherapy"},"content":{"rendered":"<div class=\"xn-newslines\">\n<h2 class=\"xn-hedline\">Understanding Mechanism of Action of Novel Cancer Therapy Previously Used Outside of USA Supports Response to FDA Regarding Currently Pending Investigational New Drug Application<\/h2>\n<p class=\"xn-distributor\">PR Newswire<\/p>\n<\/p><\/div>\n<div class=\"xn-content\">\n<p>\n        <span class=\"xn-location\">OCEANSIDE, Calif.<\/span>, <span class=\"xn-chron\">Jan. 19, 2021<\/span> \/PRNewswire\/ &#8212; Therapeutic Solutions International, Inc., (OTC Markets: TSOI), reported positive animal data in the 4T1 breast cancer model using its clinically tested StemVacs\u2122 cellular immunotherapy.\u00a0 <\/p>\n<p>In a series of experiments, it was demonstrated that StemVacs\u2122 administration resulted in a) regression of established breast cancer in mice; b) that regression was dependent on natural killer cells, and c) that immunity to breast cancer could be transferred by CD4 T cells to na\u00efve mice.\u00a0 <\/p>\n<p>Previously the Company announced positive safety data in 10 patients treated with StemVacs\u2122<sup>1<\/sup>.\u00a0 Additionally, the Company has filed an Investigational New Drug Application (IND) which is currently pending based on the Company responding to questions posed by the FDA.<\/p>\n<p>&#8220;The current data, which conclusively demonstrates the induction of immunological memory to cancer, as well as the natural killer cell as a mechanism of action, will position us to provide the FDA responses to their questions from our submitted IND,&#8221; said Dr. <span class=\"xn-person\">James Veltmeyer<\/span>, Chief Medical Officer of the Company and voted Top Doctor of <span class=\"xn-location\">San Diego<\/span>. &#8220;Given the fact that we have human safety data from outside of <span class=\"xn-location\">the United States<\/span>, combined with these new mechanistic findings, we are confident in a smooth interaction with the FDA as we get closer to clearing of our IND application.&#8221;<\/p>\n<p>&#8220;It is known that numerous immunotherapies such as Herceptin\u00ae are dependent on the ability of natural killer cells to function properly,&#8221; said <span class=\"xn-person\">Famela Ramos<\/span>, Vice President of Business Development. &#8220;The current data provides a scientific basis for us to collaborate with other immuno-oncology companies to identify and leverage possible synergies with other drugs that work via the natural killer pathway of the innate immune system.&#8221;<\/p>\n<p>&#8220;Therapeutic Solutions International is a &#8216;science-driven&#8217; organization,&#8221; said <span class=\"xn-person\">Timothy Dixon<\/span>, President and CEO. &#8220;Having key opinion leaders such as Drs. <span class=\"xn-person\">Santosh Kesari<\/span> and <span class=\"xn-person\">Francesco Marincola<\/span> as advisors allows us to design and execute experiments with the highest level of academic rigor.\u00a0We believe that the FDA and our scientific and medical peers will appreciate our philosophy.&#8221;<\/p>\n<p>\n        <b>About Therapeutic Solutions International, Inc.<br \/><\/b>Therapeutic Solutions International is focused on immune modulation for the treatment of several specific diseases. The Company&#8217;s corporate website is <a target=\"_blank\" href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=3039867-1&amp;h=2336185127&amp;u=http%3A%2F%2Fwww.therapeuticsolutionsint.com%2F&amp;a=www.therapeuticsolutionsint.com\" rel=\"nofollow noopener noreferrer\">www.therapeuticsolutionsint.com<\/a>, and our public forum is <a target=\"_blank\" href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=3039867-1&amp;h=2456799524&amp;u=https%3A%2F%2Fboard.therapeuticsolutionsint.com%2F&amp;a=https%3A%2F%2Fboard.therapeuticsolutionsint.com%2F\" rel=\"nofollow noopener noreferrer\">https:\/\/board.therapeuticsolutionsint.com\/<\/a> \u00a0<\/p>\n<p><sup><b>1 <\/b><\/sup><a target=\"_blank\" href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=en&amp;o=3039867-1&amp;h=4273370208&amp;u=https%3A%2F%2Fimmuno-oncologynews.com%2F2018%2F09%2F11%2Fstemvacs-cancer-vaccine-shows-safety-in-trial-may-be-eligible-for-right-to-try-therapeutic-solutions-says%2F&amp;a=StemVacs+Cancer+Vaccine+Shows+Safety+and+May+Be+Eligible+for+Right+to+Try%2C+Therapeutic+Solutions+Says+(immuno-oncologynews.com)\" rel=\"nofollow noopener noreferrer\">StemVacs Cancer Vaccine Shows Safety and May Be Eligible for Right to Try, Therapeutic Solutions Says (immuno-oncologynews.com)<\/a><\/p>\n<p>\n        <a target=\"_blank\" href=\"mailto:ir@tsoimail.com\" rel=\"nofollow noopener noreferrer\">ir@tsoimail.com<\/a>\n      <\/p>\n<p id=\"PURL\">\n        <img loading=\"lazy\" decoding=\"async\" title=\"Cision\" width=\"12\" height=\"12\" alt=\"Cision\" src=\"https:\/\/c212.net\/c\/img\/favicon.png?sn=AQ51415&amp;sd=2021-01-19\" \/> View original content:<a id=\"PRNURL\" rel=\"nofollow\" href=\"http:\/\/www.prnewswire.com\/news-releases\/therapeutic-solutions-international-reports-successful-treatment-of-breast-cancer-using-stemvacs-cellular-immunotherapy-301210088.html\">http:\/\/www.prnewswire.com\/news-releases\/therapeutic-solutions-international-reports-successful-treatment-of-breast-cancer-using-stemvacs-cellular-immunotherapy-301210088.html<\/a><\/p>\n<p>SOURCE  Therapeutic Solutions International<\/p>\n<\/p><\/div>\n<p>    <img decoding=\"async\" alt=\"\" src=\"https:\/\/rt.prnewswire.com\/rt.gif?NewsItemId=AQ51415&amp;Transmission_Id=202101190930PR_NEWS_USPR_____AQ51415&amp;DateId=20210119\" style=\"border:0px;width:1px;height:1px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Understanding Mechanism of Action of Novel Cancer Therapy Previously Used Outside of USA Supports Response to FDA Regarding Currently Pending Investigational New Drug Application PR Newswire OCEANSIDE, Calif., Jan. 19, 2021 \/PRNewswire\/ &#8212; Therapeutic Solutions International, Inc., (OTC Markets: TSOI), reported positive animal data in the 4T1 breast cancer model using its clinically tested StemVacs\u2122 cellular immunotherapy.\u00a0 In a series of experiments, it was demonstrated that StemVacs\u2122 administration resulted in a) regression of established breast cancer in mice; b) that regression was dependent on natural killer cells, and c) that immunity to breast cancer could be transferred by CD4 T cells to na\u00efve mice.\u00a0 Previously the Company announced positive safety data in 10 patients treated with StemVacs\u21221.\u00a0 Additionally, the Company &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/therapeutic-solutions-international-reports-successful-treatment-of-breast-cancer-using-stemvacs-cellular-immunotherapy\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Therapeutic Solutions International Reports Successful Treatment of Breast Cancer using StemVacs\u2122 Cellular Immunotherapy&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-416940","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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