{"id":407550,"date":"2021-01-04T09:03:32","date_gmt":"2021-01-04T14:03:32","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=407550"},"modified":"2021-01-04T09:03:32","modified_gmt":"2021-01-04T14:03:32","slug":"positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\/","title":{"rendered":"Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">VANCOUVER, British Columbia, Jan.  04, 2021  (GLOBE NEWSWIRE) &#8212; Qu Biologics Inc., a private clinical stage biopharmaceutical company developing <a href=\"http:\/\/www.qubiologics.com\/what-we-do\/how-ssis-work\/\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">Site Specific Immunomodulators<\/a> (SSIs), a novel platform of immunotherapies designed to restore innate immune function, is pleased to report positive signs of clinical, endoscopic and histologic response in subjects participating in Stage 1 of their Phase 2 RESTORE trial for the treatment of patients with moderate-to-severe Crohn\u2019s disease. These positive signals emerged from a recently completed interim analysis of Stage 1, which is designed to assess the optimal timepoint to measure endoscopic response induction in patients treated with QBECO, Qu\u2019s gastrointestinal-targeted SSI.<\/p>\n<p>Crohn\u2019s disease is a type of chronic inflammatory bowel disease (IBD) that is clinically characterized by abdominal pain, severe diarrhea, fatigue, malabsorption, and gastrointestinal distress. Current treatments are focused on symptom management through aggressive immune suppression, which can be associated with an increased risk of infection and certain types of cancers. In contrast, Qu\u2019s QBECO is designed to restore immune and barrier function in the gastrointestinal tract to overcome the damaging unproductive inflammation that patients with IBD experience.<\/p>\n<p>\u201cWe are very encouraged to see QBECO demonstrate an objective biologic effect in the gastrointestinal tract of patients with Crohn\u2019s disease, especially since this has been difficult to achieve and maintain with current therapies,\u201d said Jim Pankovich, Qu\u2019s VP of Clinical Operations and Drug Development. \u201cThese therapeutic signals were noted across a range of important endoscopic, histological and serological parameters,\u201d noted Dr. Hal Gunn, CEO of Qu, \u201cWe are excited at QBECO\u2019s potential to transform the way Crohn\u2019s disease is treated and to meaningfully improve health outcomes of people living with this challenging disease.\u201d<\/p>\n<p>Results from Stage 1 of the RESTORE Trial are anticipated to be available in February 2021. This data will inform the design of Stage 2 of the study, which is planned to be a larger international randomized placebo-controlled trial (n=150) for the treatment of patients with moderate-to-severe Crohn\u2019s disease.<\/p>\n<p>For more information about Qu Biologics and the science behind SSIs, please visit <a href=\"http:\/\/www.qubiologics.com\/\" rel=\"nofollow noopener noreferrer\" target=\"_blank\"><u>www.qubiologics.com<\/u><\/a>.<\/p>\n<p>\n        <strong>About Qu Biologics<\/strong><br \/>\n        <br \/>Qu Biologics is a clinical stage biotechnology company developing Site Specific Immunomodulators (SSI), a novel class of immunotherapies designed to stimulate an innate immune response in targeted organs to reverse the chronic inflammation underlying many important diseases including inflammatory bowel disease, cancer, inflammatory lung disease and arthritis. Qu has completed three Phase 2 studies in Crohn\u2019s disease, ulcerative colitis and lung cancer and has two Phase 2 studies underway in Crohn\u2019s disease and colon cancer.<\/p>\n<p>Backed by a prestigious group of scientific advisors and board members, Qu Biologics is led by a management team that includes co-founder and CEO Dr. Hal Gunn, a physician and expert on the body\u2019s immune response to chronic disease; and Chief Medical Officer Dr. Simon Sutcliffe, former CEO of the BC Cancer Agency and a distinguished clinician, scientist and leader in cancer control in Canada and internationally.<\/p>\n<p>For more information regarding this press release, contact:<\/p>\n<p>Hal Gunn, MD<br \/>CEO<br \/>Qu Biologics Inc.<br \/>Phone: 604.734.1450 <br \/>Email: <a href=\"mailto:media@qubiologics.com\" rel=\"nofollow noopener noreferrer\" target=\"_blank\"><u>media@qubiologics.com<\/u><\/a><\/p>\n<p>\n        <em>Qu Biologics Inc. cautions you that statements included in this press release that are not a description of historical facts may be forward-looking statements. Forward-looking statements are only predictions based upon current expectations and involve known and unknown risks and uncertainties. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of release of the relevant information, unless explicitly stated otherwise. Actual results, performance or achievement could differ materially from those expressed in, or implied by, Qu Biologics\u2019 forward-looking statements due to the risks and uncertainties inherent in Qu Biologics\u2019 business including, without limitation, statements about: the progress and timing of its clinical trials; difficulties or delays in development, testing, obtaining regulatory approval, producing and marketing its products; unexpected adverse side effects or inadequate therapeutic efficacy of its products that could delay or prevent product development or commercialization; the scope and validity of patent protection for its products; competition from other pharmaceutical or biotechnology companies; and its ability to obtain additional financing to support its operations. Qu Biologics does not assume any obligation to update any forward-looking statements except as required by law.<\/em>\n      <\/p>\n<p>      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODExOTM1MiMzOTAxMTYwIzIwODQ4MDM=\" width=\"1\" height=\"1\" \/><br \/>\n      <br \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/ml.globenewswire.com\/release\/track\/2fee1f79-6864-42e4-a23e-035d0acd412e\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>VANCOUVER, British Columbia, Jan. 04, 2021 (GLOBE NEWSWIRE) &#8212; Qu Biologics Inc., a private clinical stage biopharmaceutical company developing Site Specific Immunomodulators (SSIs), a novel platform of immunotherapies designed to restore innate immune function, is pleased to report positive signs of clinical, endoscopic and histologic response in subjects participating in Stage 1 of their Phase 2 RESTORE trial for the treatment of patients with moderate-to-severe Crohn\u2019s disease. These positive signals emerged from a recently completed interim analysis of Stage 1, which is designed to assess the optimal timepoint to measure endoscopic response induction in patients treated with QBECO, Qu\u2019s gastrointestinal-targeted SSI. Crohn\u2019s disease is a type of chronic inflammatory bowel disease (IBD) that is clinically characterized by abdominal pain, severe &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-407550","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"VANCOUVER, British Columbia, Jan. 04, 2021 (GLOBE NEWSWIRE) &#8212; Qu Biologics Inc., a private clinical stage biopharmaceutical company developing Site Specific Immunomodulators (SSIs), a novel platform of immunotherapies designed to restore innate immune function, is pleased to report positive signs of clinical, endoscopic and histologic response in subjects participating in Stage 1 of their Phase 2 RESTORE trial for the treatment of patients with moderate-to-severe Crohn\u2019s disease. These positive signals emerged from a recently completed interim analysis of Stage 1, which is designed to assess the optimal timepoint to measure endoscopic response induction in patients treated with QBECO, Qu\u2019s gastrointestinal-targeted SSI. Crohn\u2019s disease is a type of chronic inflammatory bowel disease (IBD) that is clinically characterized by abdominal pain, severe &hellip; Continue reading &quot;Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2021-01-04T14:03:32+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODExOTM1MiMzOTAxMTYwIzIwODQ4MDM=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"3 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO\",\"datePublished\":\"2021-01-04T14:03:32+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/\"},\"wordCount\":713,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=ODExOTM1MiMzOTAxMTYwIzIwODQ4MDM=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/positive-signals-for-endoscopic-and-histologic-response-in-patients-with-crohns-disease-treated-with-qu-biologics-qbeco\\\/\",\"name\":\"Positive Signals for Endoscopic and Histologic Response in Patients with Crohn\u2019s Disease Treated with Qu Biologics\u2019 QBECO - 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These positive signals emerged from a recently completed interim analysis of Stage 1, which is designed to assess the optimal timepoint to measure endoscopic response induction in patients treated with QBECO, Qu\u2019s gastrointestinal-targeted SSI. 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