{"id":404329,"date":"2020-12-22T07:48:25","date_gmt":"2020-12-22T12:48:25","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=404329"},"modified":"2020-12-22T07:48:25","modified_gmt":"2020-12-22T12:48:25","slug":"creative-medical-technology-holdings-identifies-mechanism-of-action-of-immcelz-stroke-regenerative-activity","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/creative-medical-technology-holdings-identifies-mechanism-of-action-of-immcelz-stroke-regenerative-activity\/","title":{"rendered":"Creative Medical Technology Holdings Identifies Mechanism of Action of ImmCelz\u00ae Stroke Regenerative Activity"},"content":{"rendered":"
\n

Company Reports Superior Production of Growth Factors and Therapeutic Immune Cells as Compared with Other Stem Cell Types<\/h2>\n

PR Newswire<\/p>\n<\/p><\/div>\n

\n

\n PHOENIX<\/span>, Dec. 22, 2020<\/span> \/PRNewswire\/ —\u00a0Creative Medical Technology Holdings Inc. (OTC \u2013 CELZ)\u00a0 announced today data identifying one of the primary mechanisms of action of its ImmCelz\u00ae product in the treatment of stroke. The Company reported that animals having previously been treated with ImmCelz\u00ae have an increase in what is called “endogenous neurogenesis”.\u00a0 This process allows for certain parts of the brain to heal themselves more effectively after injury, for example, such as in stroke. The stimulation of endogenous neurogenesis was approximately 85% higher than in animals treatment with a popular type of stem cell termed mesenchymal stem cells. Additionally, the Company reported that depletion of animals of T regulatory cells resulted in suppression of endogenous neurogenesis. <\/p>\n

\n

\n
\n \"Creative
\n <\/a>\n <\/p>\n<\/p><\/div>\n

“These findings are continuation of work initiated years ago in which we sought to dissect not only immunological mechanisms of ImmCelz\u00ae activity, but also other physiological systems, including the nervous system.” Said Dr. Amit Patel<\/span>, Board Member of the Company. “The elucidation of a mechanism of action makes ImmCelz\u00ae an increasingly viable candidate for FDA IND application and initiation of clinical trials.”<\/p>\n

In contrast to stem cell based approaches, ImmCelz\u00ae is an immunotherapy product in which stem cells are used to “educate” immune cells to endow them with regenerative activity.\u00a0 <\/p>\n

The Company believes that “educated” immune cells may be superior to stem cells because of their: a) ability to replicate and form “memory” cells; b) substantially smaller size, which allows for superior biodistribution than stem cells; and c) adeptness at surviving in conditions such as hypoxia or acidosis, which would inactivate stem cells.<\/p>\n

“I would like to thank my colleagues who have steadily worked tirelessly on this project for years. The possibility of immune cells being coaxed into possessing regenerative activity is quite a revolutionary concept, which thanks to these recent experiments appears to be becoming a reality.” Said Thomas E Ichim, Ph.D, Chief Scientific Officer and co-inventor of ImmCelz\u00ae. <\/p>\n

“Stroke represents a significant unmet medical need for which numerous other approaches have failed.” Said Timothy Warbington<\/span>, President and CEO of the Company. “By understanding the biological switches that ImmCelz\u00ae activates to reduce stroke in animals, we believe that our path through the FDA will be less challenging, as well as our road to eventual commercialization.”<\/p>\n

\n About Creative Medical Technology Holdings<\/b>\n <\/p>\n

Creative Medical Technology Holdings, Inc. is a commercial stage biotechnology company specializing in stem cell technology in the fields of urology, neurology and orthopedics and trades on the OTC under the ticker symbol CELZ. For further information about the company, please visit\u00a0www.creativemedicaltechnology.com<\/a>.\u00a0<\/b><\/p>\n

\n Forward Looking Statements<\/b>\n <\/p>\n

OTC Markets has not reviewed and does not accept responsibility for the adequacy or accuracy of this release. This news release may contain forward-looking statements including but not limited to comments regarding the timing and content of upcoming clinical trials and laboratory results, marketing efforts, funding, etc. Forward-looking statements address future events and conditions and, therefore, involve inherent risks and uncertainties. Actual results may differ materially from those currently anticipated in such statements. See the periodic and other reports filed by Creative Medical Technology Holdings, Inc. with the Securities and Exchange Commission and available on the Commission’s website at\u00a0www.sec.gov<\/a>.<\/p>\n

\n Timothy Warbington<\/span>, CEO\u00a0
CEO@CreativeMedicalHealth.com<\/a><\/p>\n

\n Creativemedicaltechnology.com<\/a>
\n
\n www.StemSpine.com<\/a>
\n
\n www.Caverstem.com<\/a>
\n
\n www.Femcelz.com<\/a>\n <\/p>\n

<\/div>\n

\n \"Cision\" View original content to download multimedia:http:\/\/www.prnewswire.com\/news-releases\/creative-medical-technology-holdings-identifies-mechanism-of-action-of-immcelz-stroke-regenerative-activity-301197267.html<\/a><\/p>\n

SOURCE Creative Medical Technology Holdings, Inc.<\/p>\n<\/p><\/div>\n

\"\"<\/p>\n","protected":false},"excerpt":{"rendered":"

Company Reports Superior Production of Growth Factors and Therapeutic Immune Cells as Compared with Other Stem Cell Types PR Newswire PHOENIX, Dec. 22, 2020 \/PRNewswire\/ —\u00a0Creative Medical Technology Holdings Inc. (OTC \u2013 CELZ)\u00a0 announced today data identifying one of the primary mechanisms of action of its ImmCelz\u00ae product in the treatment of stroke. The Company reported that animals having previously been treated with ImmCelz\u00ae have an increase in what is called “endogenous neurogenesis”.\u00a0 This process allows for certain parts of the brain to heal themselves more effectively after injury, for example, such as in stroke. The stimulation of endogenous neurogenesis was approximately 85% higher than in animals treatment with a popular type of stem cell termed mesenchymal stem cells. Additionally, … <\/p>\n

Continue reading “Creative Medical Technology Holdings Identifies Mechanism of Action of ImmCelz\u00ae Stroke Regenerative Activity”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-404329","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nCreative Medical Technology Holdings Identifies Mechanism of Action of ImmCelz\u00ae Stroke Regenerative Activity - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/creative-medical-technology-holdings-identifies-mechanism-of-action-of-immcelz-stroke-regenerative-activity\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Creative Medical Technology Holdings Identifies Mechanism of Action of ImmCelz\u00ae Stroke Regenerative Activity - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Company Reports Superior Production of Growth Factors and Therapeutic Immune Cells as Compared with Other Stem Cell Types PR Newswire PHOENIX, Dec. 22, 2020 \/PRNewswire\/ —\u00a0Creative Medical Technology Holdings Inc. (OTC \u2013 CELZ)\u00a0 announced today data identifying one of the primary mechanisms of action of its ImmCelz\u00ae product in the treatment of stroke. The Company reported that animals having previously been treated with ImmCelz\u00ae have an increase in what is called “endogenous neurogenesis”.\u00a0 This process allows for certain parts of the brain to heal themselves more effectively after injury, for example, such as in stroke. The stimulation of endogenous neurogenesis was approximately 85% higher than in animals treatment with a popular type of stem cell termed mesenchymal stem cells. 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