{"id":394171,"date":"2020-12-07T08:03:16","date_gmt":"2020-12-07T13:03:16","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=394171"},"modified":"2020-12-07T08:03:16","modified_gmt":"2020-12-07T13:03:16","slug":"scpharmaceuticals-inc-receives-complete-response-letter-from-fda-for-furoscix","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/scpharmaceuticals-inc-receives-complete-response-letter-from-fda-for-furoscix\/","title":{"rendered":"scPharmaceuticals Inc. Receives Complete Response Letter from FDA for FUROSCIX\u00ae"},"content":{"rendered":"

\nCRL did not identify clinical deficiencies
\n<\/h2>\n
\n

BURLINGTON, Mass., Dec. 07, 2020 (GLOBE NEWSWIRE) — scPharmaceuticals Inc. (Nasdaq: SCPH), a pharmaceutical company focused on developing and commercializing products that have the potential to optimize the delivery of infused therapies, advance patient care, and reduce healthcare costs, today announced it received a Complete Response Letter (\u201cCRL\u201d) from the U.S. Food and Drug Administration (\u201cFDA\u201d) on December 3, 2020 regarding the Company\u2019s New Drug Application (\u201cNDA\u201d) for FUROSCIX\u00ae.<\/p>\n

In the CRL, the FDA cited their need to conduct pre-approval inspections at two of the company\u2019s third-party manufacturing facilities that could not be conducted due to travel restrictions. In addition, the FDA raised questions related to testing, labeling, and features of the combination product unrelated to the drug constituent. In addition, the FDA indicated that there were deficiencies at the third-party facility where the Company\u2019s off-the-shelf alcohol swabs are manufactured. scPharmaceuticals will request a Type A meeting with the FDA to discuss the issues described in the CRL and steps required for the resubmission of the NDA for FUROSCIX\u00ae.<\/p>\n

scPharmaceuticals ended the third quarter with cash, cash equivalents, restricted cash, and investments of $114.5 million, which the Company estimates is sufficient to fund operations into 2023 at the projected burn rate.<\/p>\n

John Tucker, Chief Executive Officer of scPharmaceuticals, stated: \u201cWhile we are disappointed that these on-site inspections, and other issues raised in the CRL, will not be resolved by our previously granted December 30, 2020 PDUFA date, we are committed to working with our manufacturing partners and responding to the agency\u2019s concerns as expeditiously as possible. We continue to believe that FUROSCIX\u00ae can play a significant role in preventing heart failure hospital admissions and readmissions due to fluid overload by intervening with this novel therapy at home.\u201d<\/p>\n

\n About FUROSCIX<\/strong>
\n \u00ae <\/strong>(furosemide injection) for subcutaneous injection
FUROSCIX is a proprietary furosemide solution formulated to a neutral pH to allow for subcutaneous infusion via a wearable, pre-programmed on-body drug delivery system, for outpatient self-administration. FUROSCIX is currently under development for the treatment of congestion due to fluid overload in adult patients with worsening\u00a0New York Heart Association\u00a0(NYHA) Class II and Class III heart failure who display reduced responsiveness to oral diuretics and who do not require hospitalization. FUROSCIX has the potential to provide an outpatient alternative for the treatment of worsening heart failure due to congestion.<\/p>\n

\n About scPharmaceuticals
<\/strong>scPharmaceuticals is a pharmaceutical company focused on developing and commercializing products that are designed to reduce healthcare costs and improve health outcomes. The Company develops, internally and through strategic partnerships, innovative products and solutions that aim to expand and advance the outpatient care of select acute conditions. The Company\u2019s lead programs focus on the subcutaneous, self-administration of IV-strength treatments in heart failure and infectious disease. scPharmaceuticals is headquartered in Burlington, MA. For more information, please visit www.scPharmaceuticals.com<\/a><\/u>.<\/p>\n

\n Forward-Looking Statement
<\/strong>
\n This press release contains \u201cforward-looking statements\u201d within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, statements regarding the<\/em>
\n Company\u2019s request for a Type A meeting with the FDA, the outcome of the Type A meeting, the Company\u2019s ability to address the comments raised in the Complete Response Letter and resubmit the FUROSCIX NDA<\/em>
\n ,<\/em>
\n and the Company\u2019s<\/em>
\n cash runway<\/em>
\n . Any forward-looking statements in this press release are based on management\u2019s current expectations of future events and are subject to a number of risks and uncertainties that could cause actual results to differ materially and adversely from those set forth in or implied by such forward-looking statements. These risks and uncertainties include, but are not limited to, the risk of the ability of the FUROSCIX On-Body Infusor to appropriately deliver therapy, the receipt of regulatory approval for the FUROSCIX On-Body Infusor or any of our other product candidates or, if approved, the successful commercialization of such products, the risk of cessation or delay of any of the ongoing or planned clinical trials and\/or our development of our product candidates, and the risk that the current COVID-19 pandemic will impact the Company\u2019s device validation, drug stability testing, the <\/em>
\n resubmission of<\/em>
\n the Company\u2019s FUROSCIX NDA and other operations. For a discussion of other risks and uncertainties, and other important factors, any of which could cause our actual results to differ from those contained in the forward-looking statements, see the section entitled \u201cRisk Factors\u201d in its Annual Report on Form 10-K for the year ended\u00a0December 31, 2019\u00a0on file with the\u00a0Securities and Exchange Commission, available at the Securities and Exchange Commission\u2019s website at\u00a0<\/em>
\n
\n www.sec.gov<\/a>
\n <\/em>
\n , and as well as discussions of potential risks, uncertainties and other important factors in the Company\u2019s subsequent filings with the\u00a0Securities and Exchange Commission. All information in this press release is as of the date of the release, and the Company undertakes no duty to update this information unless required by law.<\/em>\n <\/p>\n

Katherine Taudvin
scPharmaceuticals Inc., 781-301-6706
ktaudvin@scpharma.com<\/a><\/p>\n

Investors:
Hans Vitzthum
LifeSci Advisors, 617-430-7578
hans@lifesciadvisors.com<\/a><\/p>\n


\n
\n \n <\/div>\n

<\/div>\n","protected":false},"excerpt":{"rendered":"

CRL did not identify clinical deficiencies BURLINGTON, Mass., Dec. 07, 2020 (GLOBE NEWSWIRE) — scPharmaceuticals Inc. (Nasdaq: SCPH), a pharmaceutical company focused on developing and commercializing products that have the potential to optimize the delivery of infused therapies, advance patient care, and reduce healthcare costs, today announced it received a Complete Response Letter (\u201cCRL\u201d) from the U.S. Food and Drug Administration (\u201cFDA\u201d) on December 3, 2020 regarding the Company\u2019s New Drug Application (\u201cNDA\u201d) for FUROSCIX\u00ae. In the CRL, the FDA cited their need to conduct pre-approval inspections at two of the company\u2019s third-party manufacturing facilities that could not be conducted due to travel restrictions. In addition, the FDA raised questions related to testing, labeling, and features of the combination product … <\/p>\n

Continue reading “scPharmaceuticals Inc. Receives Complete Response Letter from FDA for FUROSCIX\u00ae”<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-394171","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"\nscPharmaceuticals Inc. Receives Complete Response Letter from FDA for FUROSCIX\u00ae - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/scpharmaceuticals-inc-receives-complete-response-letter-from-fda-for-furoscix\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"scPharmaceuticals Inc. 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