{"id":379393,"date":"2020-11-12T07:03:37","date_gmt":"2020-11-12T12:03:37","guid":{"rendered":"http:\/\/www.marketnewsdesk.com\/?p=379393"},"modified":"2020-11-12T07:03:37","modified_gmt":"2020-11-12T12:03:37","slug":"surrozen-to-present-at-the-stifel-2020-virtual-healthcare-conference","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/surrozen-to-present-at-the-stifel-2020-virtual-healthcare-conference\/","title":{"rendered":"Surrozen to Present at the Stifel 2020 Virtual Healthcare Conference"},"content":{"rendered":"<div class=\"mw_release\">\n<p align=\"left\">SOUTH SAN FRANCISCO, Calif., Nov.  12, 2020  (GLOBE NEWSWIRE) &#8212; Surrozen Inc., a biotechnology company pioneering a new class of targeted regenerative antibodies, today announced that Craig Parker, president and chief executive officer of Surrozen, will be presenting at the Stifel 2020 Virtual Healthcare Conference. The presentation will begin at 10:40 a.m. Eastern on Monday November 16<sup>th<\/sup>, 2020. The public may access the event live via webcast at: <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=OuIPbFzixuapq62kmNLADQbIXtAEN3P3zNYQDVOP776Xl9yhVGLCFIMc8lkGCeQTMsfDc-r4fDCOgJhU49UqIy09KtkL_3Wpf7BYeVNoUxi6FdFc2nbeNgc1iSzOLPCiMGedJbdIpKsFAnmRYWK30A==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">https:\/\/wsw.com\/webcast\/stifel27\/surr\/2139584<\/a><\/p>\n<p>\n        <strong>About Wnt Signaling<\/strong><br \/>\n        <br \/>Wnt signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including liver, intestine, lung, kidney, central nervous system, cochlea, bone, and others. Modulation of Wnt signaling pathways has potential for treatment of degenerative diseases and tissue injuries. There are 19 Wnt ligands (Wnts) in mammals, and they signal through Frizzled receptors 1-10 and co-receptors LRP5 or 6, two families of receptors. Endogenous Wnts bind to multiple Frizzled receptors and are heavily modified post-translationally, making them difficult to manufacture consistently. R-spondin stabilizes Frizzled receptors, enhancing the body\u2019s response to endogenous Wnts.\u00a0<\/p>\n<p>\n        <strong>About Surrozen\u2019s\u00a0Proprietary Antibody Platforms and Harnessing Wnt Signaling<\/strong><br \/>\n        <br \/>Since its founding in 2016, Surrozen has developed two proprietary platforms to selectively modulate the Wnt pathway for the potential treatment of injury and disease. Surrozen Wnt-mimetics, also referred to as SWAP (Surrozen\u00a0Wnt signal\u00a0activating\u00a0proteins), are bi-specific full-length human (IgG) antibodies that directly activate the canonical Wnt signaling pathway in target tissue. Surrozen R-spondin-mimetics, also referred to as SWEETS (Surrozen\u00a0Wnt signal enhancers engineered for\u00a0tissue\u00a0specificity), are antibody-based molecules that enhance Wnt signaling by stabilizing Frizzled receptors\u00a0on targeted cells.<\/p>\n<p>\n        <strong>About Surrozen Preclinical Candidates<\/strong><br \/>\n        <br \/>SZN-043 is the first development candidate designed using Surrozen\u2019s SWEETS platform. In preclinical animal models of liver injury and fibrosis, SZN-043 has been shown to selectively activate Wnt signaling in the liver, stimulate hepatocyte proliferation, improve synthetic function, and reduce fibrosis. Surrozen will develop SZN-043 for severe liver diseases, including severe alcoholic hepatitis and decompensated cirrhosis.<\/p>\n<p>SZN-1326 is the first development candidate designed using Surrozen\u2019s SWAP platform. SZN-1326 targets the Wnt-signaling pathway in the intestinal epithelium. In preclinical animal models of acute and chronic colitis, SZN-1326 has been shown to activate Wnt signaling in the intestine, stimulate intestinal epithelial regeneration, and reduce disease activity. Surrozen will develop SZN-1326 for moderate to severe inflammatory bowel disease.<\/p>\n<p>\n        <strong>About Surrozen<\/strong><br \/>\n        <br \/>Surrozen is a biotechnology company pioneering a new class of targeted regenerative antibodies to repair a broad range of tissues and organs damaged by serious disease. Surrozen is designing tissue-specific antibodies that engage the body\u2019s own biological repair mechanisms resulting in a broad pipeline of disease-specific therapies to help patients across multiple disease areas, including severe liver diseases, inflammatory bowel disease, retinopathies, hearing loss, lung and airway diseases, and\u00a0certain neurological disorders. For more information, please visit\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=_sOIlWdDjLyUcm-lRVt9eBjiZ2jCO-Fd1eyA9TVVJdoMBlBsOXCZvAhIGvJwzAxF1skkd6I30R0TL-6YNqUwWQ==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">surrozen.com<\/a>.<\/p>\n<p>\n        <strong>Investors\/Partners\/Media:<\/strong><br \/>\n        <br \/>Reza Afkhami<br \/>VP, Corporate Development and Strategy<br \/>Surrozen, Inc.<br \/><a href=\"https:\/\/www.globenewswire.com\/Tracker?data=YR9xrW2sUORU2YtaVlfIpnEX_c0HoEg97TMTaIanoTCclqeqILnp7vMk2Wjg7OL7FU5vpGlhnFTkePzSjaV6zg==\" rel=\"nofollow noopener noreferrer\" target=\"_blank\">reza@surrozen.com<\/a><\/p>\n<p \/>\n      <img loading=\"lazy\" decoding=\"async\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=ODA4NDU1MyMzODIzMTg0IzIxOTU5MzM=\" width=\"1\" height=\"1\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>SOUTH SAN FRANCISCO, Calif., Nov. 12, 2020 (GLOBE NEWSWIRE) &#8212; Surrozen Inc., a biotechnology company pioneering a new class of targeted regenerative antibodies, today announced that Craig Parker, president and chief executive officer of Surrozen, will be presenting at the Stifel 2020 Virtual Healthcare Conference. The presentation will begin at 10:40 a.m. Eastern on Monday November 16th, 2020. The public may access the event live via webcast at: https:\/\/wsw.com\/webcast\/stifel27\/surr\/2139584 About Wnt Signaling Wnt signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including liver, intestine, lung, kidney, central nervous system, cochlea, bone, and others. Modulation of Wnt signaling pathways has potential for treatment of degenerative diseases and tissue injuries. There are &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/surrozen-to-present-at-the-stifel-2020-virtual-healthcare-conference\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Surrozen to Present at the Stifel 2020 Virtual Healthcare Conference&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-379393","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Surrozen to Present at the Stifel 2020 Virtual Healthcare Conference - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/surrozen-to-present-at-the-stifel-2020-virtual-healthcare-conference\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Surrozen to Present at the Stifel 2020 Virtual Healthcare Conference - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"SOUTH SAN FRANCISCO, Calif., Nov. 12, 2020 (GLOBE NEWSWIRE) &#8212; Surrozen Inc., a biotechnology company pioneering a new class of targeted regenerative antibodies, today announced that Craig Parker, president and chief executive officer of Surrozen, will be presenting at the Stifel 2020 Virtual Healthcare Conference. The presentation will begin at 10:40 a.m. Eastern on Monday November 16th, 2020. The public may access the event live via webcast at: https:\/\/wsw.com\/webcast\/stifel27\/surr\/2139584 About Wnt Signaling Wnt signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including liver, intestine, lung, kidney, central nervous system, cochlea, bone, and others. Modulation of Wnt signaling pathways has potential for treatment of degenerative diseases and tissue injuries. 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The presentation will begin at 10:40 a.m. Eastern on Monday November 16th, 2020. The public may access the event live via webcast at: https:\/\/wsw.com\/webcast\/stifel27\/surr\/2139584 About Wnt Signaling Wnt signaling plays key roles in the control of development, homeostasis, and regeneration of many essential organs and tissues, including liver, intestine, lung, kidney, central nervous system, cochlea, bone, and others. Modulation of Wnt signaling pathways has potential for treatment of degenerative diseases and tissue injuries. 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