{"id":1013140,"date":"2026-10-23T09:05:00","date_gmt":"2026-10-23T13:05:00","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/"},"modified":"2026-10-23T09:05:00","modified_gmt":"2026-10-23T13:05:00","slug":"elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/","title":{"rendered":"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine"},"content":{"rendered":"<div class=\"mw_release\">\n<ul type=\"disc\">\n<li style=\"margin-bottom:7pt\">\n          <strong><br \/>\n            <em>Multiple pre-specified subgroup analyses favored camupepimut (ELI-002 7P)<\/em><br \/>\n          <\/strong><br \/>\n          <em>, including patients with and without detectable baseline ctDNA.<\/em>\n        <\/li>\n<li style=\"margin-bottom:7pt\">\n          <strong><br \/>\n            <em>Encouraging disease-free survival outcomes were observed in both ctDNA-negative (HR 0.51) and ctDNA-positive (HR 0.57) patients<\/em><br \/>\n          <\/strong><br \/>\n          <em>.<\/em>\n        <\/li>\n<li style=\"margin-bottom:7pt\">\n          <strong><br \/>\n            <em>Baseline prognostic imbalances provide important context for the intent-to-treat results<\/em><br \/>\n          <\/strong><br \/>\n          <em>, including a 53% lower risk of recurrence or death with camupepimut (multivariable adjusted HR 0.47; p=0.0086).<\/em>\n        <\/li>\n<li style=\"margin-bottom:7pt\">\n          <strong><br \/>\n            <em>Integrated clinical and translational findings provide clear direction<\/em><br \/>\n          <\/strong><br \/>\n          <em> for refining patient stratification, optimizing dosing and advancing Phase 3 development.<\/em>\n        <\/li>\n<\/ul>\n<p>BOSTON, Oct.  23, 2026  (GLOBE NEWSWIRE) &#8212; Elicio Therapeutics, Inc. (Nasdaq: ELTX) (\u201cElicio\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing next-generation immunotherapies for KRAS-driven cancers, today announced results from the randomized Phase 2 AMPLIFY-7P study of camupepimut (ELI-002 7P), presented in a late-breaking Proffered Paper oral session at the European Society for Medical Oncology (\u201cESMO\u201d) Congress 2026 in Madrid, Spain, and simultaneously published in Nature Medicine:\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=qv6VVeO550ZugGdQP27LZmNBPDZpTPkArpNoZBxOeuCEU3M6Grmxa2CXcdzSmDEdk_xjC5mk16-G7QgV18WZ-8I6jXxbAPfpPEJhMJ0ggTzRgU9aIggDIUiiKIdBDDiNZ3jYWVVbYWucdhXoFNXru9ewnYQF4y9FtMTZpmbGlKeEx2SmluRUPXVKGp2WAHkh6iEPflxXZrNL4UVgwYiuDXbqjsWhZZ0zPSM4pItKQmKwK3y0qSLHqFWymTQn_ofl_1zPCCpxBgCHpG26Au6Xyg==\" rel=\"nofollow\" target=\"_blank\">&#8220;Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic cancer: the randomized phase 2 AMPLIFY-7P trial&#8221;<\/a>.<\/p>\n<p>Across multiple pre-specified analyses, camupepimut demonstrated consistent and favorable treatment-effect trends in patients with and without detectable baseline ctDNA and in patients without prior radiation. While the study did not meet its pre-specified primary disease-free survival (\u201cDFS\u201d) endpoint in the intent-to-treat (\u201cITT\u201d) population (HR 0.85), the results should be considered in the context of a baseline imbalance in ctDNA positivity, a strong predictor of recurrence, which was more prevalent in the camupepimut arm (20.8% vs. 12.5%). Translational analyses also demonstrated broad, persistent mutant KRAS-specific T-cell responses associated with longer DFS. Together, these findings inform a refined Phase 3 development strategy.<\/p>\n<p>\u201cThe AMPLIFY-7P results provide important new insights into camupepimut\u2019s clinical activity and reinforce our confidence in its potential for patients with pancreatic cancer,\u201d said Robert Connelly, President and Chief Executive Officer of Elicio. \u201cWe are encouraged by the consistent treatment-effect trends across pre-specified patient groups, including patients with and without detectable baseline ctDNA, and by the strong mKRAS-specific immune responses associated with clinical outcomes. These insights give us clear direction for our potential Phase 3 strategy.\u201d<\/p>\n<p>\n        <strong>Pre-Specified Analyses Show Consistent Treatment-Effect Direction Across Baseline ctDNA Subgroups<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:7pt\">In the 93 patients with baseline ctDNA-negative status, median DFS was not reached in the camupepimut arm vs. 21.2 months in the observation arm (HR 0.51; nominal p=0.0280). Recurrence or death was observed in 27.4% (17\/62) of camupepimut-treated patients vs. 48.4% (15\/31) of patients in observation.<\/li>\n<li style=\"margin-bottom:7pt\">A consistent treatment effect was also observed in the smaller, higher-risk baseline ctDNA-positive subgroup (n=26). Median DFS was 4.3 months with camupepimut vs. 1.9 months with observation (HR 0.57; nominal p=0.0489).<\/li>\n<li style=\"margin-bottom:7pt\">Prior radiation predicted lower baseline lymphocyte counts and reduced camupepimut-induced mKRAS T cell responses. In pre-specified analysis, patients who had not received prior radiation (n=106) had median DFS of 23.8 months with camupepimut vs. 10.4 months with observation (HR 0.59; nominal p=0.0221).\n<\/li>\n<\/ul>\n<table style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;border-collapse: collapse;width:100%;border-collapse:collapse\">\n<tr>\n<td style=\"max-width:24%;width:24%;min-width:24%;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;vertical-align: top\">\n            <strong>Pre-specified Subgroup<\/strong>\n          <\/td>\n<td style=\"max-width:22%;width:22%;min-width:22%;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\n            <strong>Arm<\/strong>\n          <\/td>\n<td style=\"max-width:10%;width:10%;min-width:10%;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\n            <strong>N<\/strong>\n          <\/td>\n<td style=\"max-width:22%;width:22%;min-width:22%;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\n            <strong>Median DFS<\/strong>\n          <\/td>\n<td style=\"max-width:22%;width:22%;min-width:22%;border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">\n            <strong>HR, p-value<\/strong>\n          <\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: middle\">ctDNA negative<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Camupepimut<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">62<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Not Reached<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">HR 0.51<\/td>\n<\/tr>\n<tr>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Observation<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">31<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">21.2 Months<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">P=0.0280<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: middle\">ctDNA positive<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Camupepimut<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">20<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">4.3 Months<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">HR 0.57<\/td>\n<\/tr>\n<tr>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Observation<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">6<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">1.9 Months<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">P=0.0489<\/td>\n<\/tr>\n<tr>\n<td rowspan=\"2\" style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: middle\">No Prior Radiation<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Camupepimut<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">73<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">23.8 Months<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">HR 0.59<\/td>\n<\/tr>\n<tr>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">Observation<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">33<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">10.4 Months<\/td>\n<td style=\"border-top: solid black 1pt;border-right: solid black 1pt;border-bottom: solid black 1pt;border-left: solid black 1pt;text-align: center;vertical-align: middle;vertical-align: top\">P=0.0221<\/td>\n<\/tr>\n<\/table>\n<p>\n        <strong><br \/>\n          <br \/>Baseline Prognostic Imbalance Provides Important Context for ITT Results<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:7pt\">Baseline ctDNA status emerged as a particularly strong prognostic marker. In a pooled analysis across treatment groups, median DFS was 4.2 months for ctDNA-positive patients versus 24.0 months for ctDNA-negative patients (HR 6.56; nominal p&lt;0.000001). Patients with baseline ctDNA positivity were more prevalent in the camupepimut arm (20.8%; 20\/96) than in the observation arm (12.5%; 6\/48).<\/li>\n<li style=\"margin-bottom:7pt\">A multivariable model adjusting for baseline factors estimated an association between camupepimut treatment and lower recurrence risk (adjusted HR 0.47; p=0.0086), while elevated CA19-9 (adjusted HR 3.16; p&lt;0.0001) and positive baseline ctDNA (adjusted HR 5.99; p&lt;0.0001) were associated with higher risk.<\/li>\n<\/ul>\n<p>\n        <strong>Early DFS Separation and Immune Findings Support Further Evaluation<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:7pt\">Six-month DFS was 75.7% with camupepimut vs. 61.7% with observation, a 14.0 percentage-point difference immediately following the treatment period supports evaluating treatment duration in future studies.<\/li>\n<li style=\"margin-bottom:7pt\">Camupepimut induced mutant KRAS-specific T-cell responses in 99% of evaluable treated patients (median 44.3-fold increase from baseline. Among patients evaluated for T-cell subsets, 85% generated both CD4 and CD8 responses. Responses persisted at least 46 weeks from baseline in 95.5% of evaluable treated patients; 13 of 15 patients in a selected subset showed responses to additional tumor targets.<\/li>\n<li style=\"margin-bottom:7pt\">In an exploratory analysis, stronger camupepimut-induced mutant KRAS-specific T-cell responses were associated with significantly longer DFS. Median DFS was not reached among patients with immune responses above a previously identified threshold (82%, 74\/90) vs. 6.08 months among those below the threshold (HR 0.22; nominal p&lt;0.0001).<\/li>\n<\/ul>\n<p>\n        <strong>Generally Well-Tolerated Safety Profile<\/strong>\n      <\/p>\n<ul type=\"disc\">\n<li style=\"margin-bottom:7pt\">Camupepimut was generally well tolerated, with no new safety signals observed. Grade 3 or higher adverse events occurred in 10.4% of patients receiving camupepimut vs. 14.6% under observation; serious adverse events occurred in 6.3% and 8.3%, respectively. No adverse events led to withdrawal of study medication.<\/li>\n<\/ul>\n<p>\u201cThe Phase 2 translational findings build on and reinforce our Phase 1 observations, demonstrating that camupepimut generates broad and persistent mutant KRAS-specific T-cell responses, with stronger immune responses associated with longer DFS,\u201d said Christopher Haqq, M.D., Ph.D., Executive Vice President, Head of Research and Development and Chief Medical Officer of Elicio. \u201cThese observations across both baseline ctDNA subgroups and camupepimut\u2019s favorable safety and tolerability profile provide a strong scientific and clinical rationale for a refined Phase 3 design incorporating optimized patient stratification, extended treatment duration and potential combination approaches.\u201d<\/p>\n<p>\n        <strong>Implications for Further Development<\/strong>\n      <\/p>\n<p>Elicio plans to discuss the totality of AMPLIFY-7P findings with the U.S. Food and Drug Administration to inform a potential Phase 3 study in adjuvant pancreatic cancer. Areas for consideration include baseline ctDNA and other prognostic factors in stratification and patient selection, treatment duration, and combination strategies intended to deepen or sustain mutant KRAS-specific immune activity. Any future study design remains subject to regulatory discussion and further development planning.<\/p>\n<p>\n        <strong>About the AMPLIFY-7P Phase 2 Study<\/strong>\n      <\/p>\n<p>AMPLIFY-7P Phase 2 is a randomized study evaluating camupepimut versus observation in patients with mutant KRAS-driven pancreatic ductal adenocarcinoma following completion of standard locoregional therapy. The study enrolled 144 patients across 24 U.S. clinical sites.<\/p>\n<p>\n        <strong>About ELI-002<\/strong>\n      <\/p>\n<p>Elicio\u2019s lead product candidate, ELI-002, is a structurally novel investigational Amphiphile (\u201cAMP\u201d) cancer immunotherapy that targets cancers driven by mutations in the KRAS gene, a prevalent driver of many human cancers. ELI-002 is comprised of AMP-modified mutant KRAS peptide antigens and ELI-004, an AMP-modified CpG oligodeoxynucleotide adjuvant, and is available as an off-the-shelf subcutaneous administration.<\/p>\n<p>Camupepimut (ELI-002 7P), the seven-peptide formulation, was evaluated in the randomized Phase 2 AMPLIFY-7P trial in patients with mKRAS-driven pancreatic cancer. The ELI-002 7P formulation is designed to provide immune response coverage against seven of the most common KRAS mutations present across multiple solid tumors.<\/p>\n<p>\n        <strong>About Elicio Therapeutics<\/strong>\n      <\/p>\n<p>Elicio Therapeutics, Inc. (Nasdaq: ELTX) is a clinical-stage biotechnology company advancing next-generation immunotherapies for the treatment of KRAS-driven cancers, including mKRAS-positive pancreatic and colorectal cancers. Elicio intends to build on recent clinical findings in the personalized cancer immunotherapy space to develop effective, off-the-shelf immunotherapies.<\/p>\n<p>Elicio\u2019s AMP technology aims to enhance the education, activation and amplification of cancer-specific T cells relative to conventional immunotherapy strategies, with the goal of promoting durable cancer immunosurveillance in patients. Elicio\u2019s ELI-002 7P lead program is an off-the-shelf immunotherapy candidate targeting the most common KRAS mutations, which drive approximately 25% of all solid tumors.<\/p>\n<p>Off-the-shelf immunotherapy approaches have the potential benefits of low cost, rapid, commercial-scale manufacturing and rapid availability of drug to patients, especially in neoadjuvant settings and for prophylaxis in high-risk patients, contrary to personalized immunotherapy approaches.<\/p>\n<p>Elicio\u2019s pipeline includes additional off-the-shelf therapeutic cancer immunotherapy candidates, including ELI-007 and ELI-008, which target BRAF-driven cancers and p53 hotspot mutations, respectively.<\/p>\n<p>For more information, please visit www.elicio.com.<\/p>\n<p>\n        <strong>Elicio Cautionary Note on Forward-Looking Statements<\/strong>\n      <\/p>\n<p>Certain statements contained in this communication regarding matters that are not historical facts are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended, and the Private Securities Litigation Reform Act of 1995, known as the PSLRA.<\/p>\n<p>These include statements regarding the timing and content of Elicio\u2019s presentation at ESMO Congress 2026; the clinical activity, therapeutic potential and potential benefits of camupepimut (ELI-002 7P); the interpretation and potential implications of results and analyses from the AMPLIFY-7P study; the potential for new pre-specified analyses to further characterize the clinical activity of camupepimut (ELI-002 7P); the potential for such analyses and the totality of AMPLIFY-7P findings to inform or support a refined Phase 3 development strategy; the potential benefits and effectiveness of off-the-shelf immunotherapy approaches; and other statements regarding management\u2019s intentions, plans, beliefs, expectations or forecasts for the future and, therefore, you are cautioned not to place undue reliance on them.<\/p>\n<p>No forward-looking statement can be guaranteed, and actual results may differ materially from those projected. Elicio undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise, except to the extent required by law.<\/p>\n<p>Elicio uses words such as \u201canticipates,\u201d \u201cbelieves,\u201d \u201cplans,\u201d \u201cexpects,\u201d \u201cprojects,\u201d \u201cfuture,\u201d \u201cintends,\u201d \u201cmay,\u201d \u201cwill,\u201d \u201cshould,\u201d \u201ccould,\u201d \u201cestimates,\u201d \u201cpredicts,\u201d \u201cpotential,\u201d \u201ccontinue,\u201d \u201cguidance,\u201d and similar expressions to identify forward-looking statements intended to be covered by the safe-harbor provisions of the PSLRA.<\/p>\n<p>Such forward-looking statements are based on Elicio\u2019s expectations and involve risks and uncertainties; consequently, actual results may differ materially from those expressed or implied in the statements due to a number of factors, including, but not limited to, Elicio\u2019s plans to develop and commercialize its product candidates, including camupepimut; the timing of the availability and presentation of data from Elicio\u2019s clinical trials; Elicio\u2019s plans to research, develop and commercialize its current and future product candidates; the design and timing of future clinical trials; and Elicio\u2019s estimates regarding future revenue, expenses, capital requirements and need for additional financing.<\/p>\n<p>New factors emerge from time to time, and it is not possible for Elicio to predict all such factors, nor can Elicio assess the impact of each such factor on the business or the extent to which any factor, or combination of factors, may cause actual results to differ materially from those contained in any forward-looking statements.<\/p>\n<p>These risks are more fully discussed under the heading \u201cRisk Factors\u201d in Elicio\u2019s Annual Report on Form 10-K for the year ended December 31, 2025, filed with the SEC on March 12, 2026, as amended on April 29, 2026, Elicio\u2019s Quarterly Report on Form 10-Q for the quarter ended March 31, 2026, filed with the SEC on May 11, 2026, and Elicio\u2019s Quarterly Report on Form 10-Q for the quarter ended June 30, 2026, filed with the SEC on August 13, 2026 , as updated by subsequent reports and other documents filed from time to time with the SEC.<\/p>\n<p>Forward-looking statements included in this release are based on information available to Elicio as of the date of this release. Elicio does not undertake any obligation to update such forward-looking statements to reflect events or circumstances after the date of this release, except to the extent required by law.<\/p>\n<p>\n        <strong>Elicio Investor Relations Contact<\/strong>\n      <\/p>\n<p>Brian Ritchie<br \/>LifeSci Advisors<br \/>(212) 915-2578<br \/>britchie@lifesciadvisors.com<\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTg1MTk1OCM3OTEyODY0IzIyMDg2Nzk=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/ZGNiMjk3MzUtZjgxMi00NWM5LTgxNDktOGFhZGI0MmNlNTI0LTEyMjAyMzItMjAyNi0xMC0yMy1lbg==\/tiny\/Elicio-Therapeutics-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Multiple pre-specified subgroup analyses favored camupepimut (ELI-002 7P) , including patients with and without detectable baseline ctDNA. Encouraging disease-free survival outcomes were observed in both ctDNA-negative (HR 0.51) and ctDNA-positive (HR 0.57) patients . Baseline prognostic imbalances provide important context for the intent-to-treat results , including a 53% lower risk of recurrence or death with camupepimut (multivariable adjusted HR 0.47; p=0.0086). Integrated clinical and translational findings provide clear direction for refining patient stratification, optimizing dosing and advancing Phase 3 development. BOSTON, Oct. 23, 2026 (GLOBE NEWSWIRE) &#8212; Elicio Therapeutics, Inc. (Nasdaq: ELTX) (\u201cElicio\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing next-generation immunotherapies for KRAS-driven cancers, today announced results from the randomized Phase 2 AMPLIFY-7P study of camupepimut (ELI-002 7P), &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-1013140","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"Multiple pre-specified subgroup analyses favored camupepimut (ELI-002 7P) , including patients with and without detectable baseline ctDNA. Encouraging disease-free survival outcomes were observed in both ctDNA-negative (HR 0.51) and ctDNA-positive (HR 0.57) patients . Baseline prognostic imbalances provide important context for the intent-to-treat results , including a 53% lower risk of recurrence or death with camupepimut (multivariable adjusted HR 0.47; p=0.0086). Integrated clinical and translational findings provide clear direction for refining patient stratification, optimizing dosing and advancing Phase 3 development. BOSTON, Oct. 23, 2026 (GLOBE NEWSWIRE) &#8212; Elicio Therapeutics, Inc. (Nasdaq: ELTX) (\u201cElicio\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing next-generation immunotherapies for KRAS-driven cancers, today announced results from the randomized Phase 2 AMPLIFY-7P study of camupepimut (ELI-002 7P), &hellip; Continue reading &quot;Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-23T13:05:00+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTg1MTk1OCM3OTEyODY0IzIyMDg2Nzk=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"9 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine\",\"datePublished\":\"2026-10-23T13:05:00+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/\"},\"wordCount\":1786,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTg1MTk1OCM3OTEyODY0IzIyMDg2Nzk=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\\\/\",\"name\":\"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine - 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(Nasdaq: ELTX) (\u201cElicio\u201d or the \u201cCompany\u201d), a clinical-stage biotechnology company developing next-generation immunotherapies for KRAS-driven cancers, today announced results from the randomized Phase 2 AMPLIFY-7P study of camupepimut (ELI-002 7P), &hellip; Continue reading \"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/","og_site_name":"Market Newsdesk","article_published_time":"2026-10-23T13:05:00+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTg1MTk1OCM3OTEyODY0IzIyMDg2Nzk=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"9 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine","datePublished":"2026-10-23T13:05:00+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/"},"wordCount":1786,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTg1MTk1OCM3OTEyODY0IzIyMDg2Nzk=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/elicio-therapeutics-presents-late-breaking-phase-2-amplify-7p-results-at-esmo-congress-2026-and-announces-simultaneous-publication-in-nature-medicine\/","name":"Elicio Therapeutics Presents Late-Breaking Phase 2 AMPLIFY-7P Results at ESMO Congress 2026 and Announces Simultaneous Publication in Nature Medicine - 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