{"id":1007303,"date":"2026-10-01T01:06:07","date_gmt":"2026-10-01T05:06:07","guid":{"rendered":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/"},"modified":"2026-10-01T01:06:07","modified_gmt":"2026-10-01T05:06:07","slug":"regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies","status":"publish","type":"post","link":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/","title":{"rendered":"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies"},"content":{"rendered":"<div class=\"mw_release\">\n<p>\n        <strong>REGN20423, a clinical-stage long-acting IL-13 monoclonal antibody invented and developed by Regeneron, is added to the alliance, along with a long-acting IL-4xIL-13 bispecific and two other long-acting preclinical antibodies from Regeneron<\/strong>\n      <\/p>\n<p>\n        <strong>Regeneron to receive $1 billion upfront with potential for up to an additional $7 billion in future milestone payments; companies to equally share development and commercialization costs, as well as any future profits<\/strong>\n      <\/p>\n<p>\n        <strong>Regeneron and Sanofi to host a conference call for investors and analysts today at 8:00 am ET\/2:00 pm CET<\/strong>\n      <\/p>\n<p>TARRYTOWN, N.Y. and PARIS, Oct.  01, 2026  (GLOBE NEWSWIRE) &#8212; Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced an expansion of their long-standing antibody collaboration, adding multiple next-generation, long-acting antibodies to the alliance that has jointly established Dupixent<sup>\u00ae<\/sup> (dupilumab) as the world-leading treatment for diseases driven by type 2 inflammation. The agreement builds on the companies\u2019 more than 20-year collaboration, through which more than 1.5 million people are currently receiving Dupixent across nine indications, making it one of the most widely used antibody medicines in the world.<\/p>\n<p>\u201cThe Regeneron-Sanofi alliance has been one of the most productive in biopharma history. This agreement builds on that foundation to bring the next generation of immunology medicines to patients even faster,\u201d said Leonard S. Schleifer, M.D., Ph.D., Board co-Chair, President and Chief Executive Officer of Regeneron. \u201cBy expanding our alliance, we are positioning promising new long-acting antibodies for the kind of rapid, global impact that our shared work on Dupixent has already achieved.\u201d<\/p>\n<p>Under the expanded license and collaboration agreement, the companies will co-develop and co-commercialize four new long-acting, Regeneron-invented antibodies targeting interleukin-13 (IL-13), IL-4xIL-13 bispecific, interleukin-4 (IL-4) and interleukin-4 receptor alpha (IL-4R\u03b1). IL-13 antibody REGN20423 is currently in a Phase 1 clinical trial for atopic dermatitis, and the other three antibodies are expected to enter clinical studies in 2027. Regeneron will also have the option to include in the collaboration Sanofi\u2019s lunsekimig, an investigational bispecific Nanobody<sup>\u00ae<\/sup> VHH therapy targeting TSLP and IL-13, exercisable upon completion of its Phase 3 trials for chronic obstructive pulmonary disease.<\/p>\n<p align=\"justify\">\u201cThis is a deliberate first step in igniting Sanofi\u2019s innovation engine. Our longstanding Alliance with Regeneron has transformed the treatment landscape for millions of patients living with diseases driven by type 2 inflammation and created one of the world&#8217;s leading immunology businesses,\u201d said Bel\u00e9n Garijo, Chief Executive Officer of Sanofi. \u201cBy deepening our collaboration, we will make rapid progress in creating the next generation of meaningful therapies for patients with immune-mediated diseases, while contributing to Sanofi\u2019s long-term future.\u201d<\/p>\n<p>Under the terms of the agreement, Regeneron will receive an upfront payment of $1 billion from Sanofi, with the potential for development, regulatory and commercial milestone payments of up to an additional $7 billion. The companies will share development and commercialization costs for the new programs and will split future profits from these potential products 50:50 on a global basis. Regeneron will lead research and development activities, and Sanofi will lead global commercial efforts. The existing profit-sharing agreement regarding Dupixent will not change.<\/p>\n<p>\u201cThe companies\u2019 clinical and commercial alliance dates to 2003 and has resulted in multiple approved medicines to date, including Dupixent which has redefined the standard of care for people with type 2 inflammatory diseases and is now one of the most widely used antibodies for any disease, with over 1.5 million active patients worldwide,\u201d said\u00a0George\u00a0D. Yancopoulos, M.D., Ph.D., Board co-Chair, President and Chief Scientific Officer at\u00a0Regeneron, and a principal inventor of Dupixent. \u201cBy combining Regeneron\u2019s world-class scientific discovery and antibody development expertise with Sanofi\u2019s global capabilities and reach, we hope to once again deliver the next wave of innovation in immunology.\u201d<\/p>\n<p>The companies have settled their prior collaboration-related litigation.<\/p>\n<p>\n        <strong>Conference call for investors and analysts<\/strong><br \/>\n        <br \/>Regeneron and Sanofi will host a conference call for investors and analysts today at 8:00 am ET\/2:00 pm CET. A presentation will be available for download from the Investor Relations section of regeneron.com and sanofi.com when the conference call starts.<\/p>\n<p>Participants may access today&#8217;s conference call live via webcast on the &#8216;Investors and Media&#8217; page of Regeneron&#8217;s website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B-jOTYJYAlGZjH2hYywIHS-Rri4wdpCLGUR-dgU9ICEA6Iqv3V4U8zeRnSzV6FiOQJ7bBCDCjvWClj-pxNESW43VA9EI3Jo8b0sriqZiUuJbsznCtFkft0hUNK3YA_wzFQ-n8gnSgZ68UAoeuJFj96tgrJ4ufuX0Ju9fcc6xZRcz6muJgMXa5ueqjedHTGg5\" rel=\"nofollow\" target=\"_blank\">https:\/\/investor.regeneron.com\/events-and-presentations<\/a> and on the \u2018Upcoming Events\u2019 page of Sanofi\u2019s website at\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B-jOTYJYAlGZjH2hYywIHV3vFJ3ZY0PW5cePMLZ2QMBLD0e-Q5ggoNmN3G4QeZprqeF5iCjM6VH-C-V3MNgvm8SBHjfnSFf7OqdM2NX6JwGwg3Q2OumgaWe7wTzHBFlt3VEG_wRPMOxx5oF0FrNIdOL0tpuFMM7LUpT4Lmgqh0lX-blQEugNtcNj4fF9DKCcVMmq95MbLSinOwpj6n8tjQ==\" rel=\"nofollow\" target=\"_blank\">https:\/\/www.sanofi.com\/en\/investors\/news-events\/upcoming-events<\/a>. To participate via telephone, please register in advance <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=nPDSYGy3crMY9hZg0swb3r71HQxhNbwDy4HYHLgzomdiP_OtUdjEBIEvjCoOogrJse1Pm-2bPROJ4-_i52ES9PY1EOahEVsUscIfwMC5ycUAbcybF08C87Uz04RExZRrPPaXipWPTu18T6p1E5n4y8FlmXSECoq_raWejJC_m_E=\" rel=\"nofollow\" target=\"_blank\">at this link<\/a>. Upon registration, all telephone participants will receive a confirmation email detailing how to join the conference call, including the dial-in number along with a unique passcode and registrant ID that can be used to access the call.<\/p>\n<p align=\"justify\">\n        <strong>About Dupixent<\/strong><br \/>\n        <br \/>Dupixent, which was invented using Regeneron\u2019s proprietary <em>VelocImmune<sup>\u00ae<\/sup><\/em>technology, is a fully human monoclonal antibody that inhibits the signaling of the interleukin-4 (IL-4) and interleukin-13 (IL-13) pathways and is not an immunosuppressant. The Dupixent development program has shown significant clinical benefit and a decrease in type 2 inflammation in Phase 3 studies, establishing that IL-4 and IL-13 are two of the key and central drivers of the type 2 inflammation that plays a major role in multiple related and often co-morbid diseases.<\/p>\n<p>Dupixent has received regulatory approvals in more than 60 countries in one or more indications including certain patients with atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, prurigo nodularis, chronic spontaneous urticaria, chronic obstructive pulmonary disease, bullous pemphigoid, and allergic fungal rhinosinusitis in different age populations. In addition to the currently approved indications, Sanofi and Regeneron are studying dupilumab in a broad range of diseases driven by type 2 inflammation or other allergic processes in phase 3 studies, including chronic pruritus of unknown origin. These potential uses of dupilumab are currently under clinical investigation, and the safety and efficacy in these conditions have not been fully evaluated by any regulatory authority.<\/p>\n<p>\n        <strong>Select Dupixent Safety Information for US Patients<\/strong><br \/>\n        <br \/>Dupixent is contraindicated in patients with known hypersensitivity to dupilumab or any of its excipients. Warnings and precautions include hypersensitivity reactions; conjunctivitis,\u00a0keratitis,\u00a0and blepharitis; eosinophilic conditions; acute asthma\u00a0symptoms or chronic obstructive pulmonary disease or acute deteriorating disease; risk associated with abrupt reduction of corticosteroid dosage; psoriasis;\u00a0arthralgia and psoriatic arthritis; parasitic (helminth) infections; and avoidance of live vaccines. The most common adverse reactions vary by indication and include injection site reactions, conjunctivitis, blepharitis, oral herpes, keratitis, eye pruritus, other herpes viral infection, dry eye, eosinophilia,\u00a0oropharyngeal pain, insomnia, toothache, gastritis, arthralgia, upper respiratory tract infections, nasopharyngitis, dizziness, myalgia, diarrhea, viral infection, headache, back pain, urinary tract infection, rhinitis, and blurred vision.<\/p>\n<p>\n        <em>Please<\/em><br \/>\n        <em>s<\/em><br \/>\n        <em>e<\/em><br \/>\n        <em>e full <\/em><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=Vz9zhA32zhqB7y2aUQoqx7UdiBJxXr0NASZ0gsnBRNUAWU5jvGUxcnxS_D3wyHZ8ut4KbvZge2c9PH0yZQvtLm8rrivygEG_PuQgaGxleKcMdlshSRkJPFIKZyvDJreIfmxHGoDEJ47gWLG8XtStYw==\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <em>Dupixent Prescribing Information<\/em><br \/>\n        <\/a><br \/>\n        <em>i<\/em><br \/>\n        <em>nc<\/em><br \/>\n        <em>l<\/em><br \/>\n        <em>ud<\/em><br \/>\n        <em>i<\/em><br \/>\n        <em>n<\/em><br \/>\n        <em>g Patient Information for complete safety information.<\/em>\n      <\/p>\n<p>\n        <strong>About Regeneron <\/strong><br \/>\n        <br \/>Regeneron (NASDAQ: REGN) is a leading biotechnology company that invents, develops and commercializes life-transforming medicines for people with serious diseases. Founded and led by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to numerous approved treatments and product candidates in development, most of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurological diseases, hematologic conditions, infectious diseases, and rare diseases.<\/p>\n<p>Regeneron pushes the boundaries of scientific discovery and accelerates drug development using our proprietary technologies, such as <em>VelociSuite<sup>\u00ae<\/sup><\/em>, which produces optimized fully human antibodies and new classes of bispecific antibodies. We are shaping the next frontier of medicine with data-powered insights from the Regeneron Genetics Center<sup>\u00ae<\/sup> and pioneering genetic medicine platforms, enabling us to identify innovative targets and complementary approaches to potentially treat or cure diseases. For more information, please visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=xamJ1sgz2oWROY-F9tD8jEBUDAl8CBjm2WH2aNWA7_K2QKj5oxkSfXKemWxf4l2jb3LF2m1NEc9lX0Cjh7MhCd7QGwmqwqECmi6sPMCKAQ4=\" rel=\"nofollow\" target=\"_blank\">www.Regeneron.com<\/a> or follow Regeneron on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=bCrpIuOExr2LEUrNJnSc-Les5nYd5wakBwy-thSp1NiGdtnIVW-FysiSw4hLhSTdbMIk1uHyDIPGRwHxOtIMfS0vhrmWJAj_RtKohmy4UCOAlYz8fbvFtNfBL625KG-c\" rel=\"nofollow\" target=\"_blank\">LinkedIn<\/a>, <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=HL1Chxa4lKnr6IAxa58_soSfR4iXc6uOjKFDrEdVQs-J3AaptoCLfOT8r_g_8Y8LSlRzGYpEeg1UT_4s6D3cfCOKc_-iqGrzB5u9WYceXfs=\" rel=\"nofollow\" target=\"_blank\">Instagram<\/a>, <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=76FrRQ5T0XGXBe_Y47Hfx85dMtOhQgVUk8q7ge480xwO6hMe7nd74XbEPIRqht0PppDl7vaFTXebbKjIByWcRt9fcKq_Zdc6waCLs2KNHTo=\" rel=\"nofollow\" target=\"_blank\">Facebook<\/a> or <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=vLF2z5Lf_Kp4Hwb8Meez1WRyww1mf7pochYO0ZjaXXibCSKSGvlhYvVs-CYpboYGZPXU6WFoaiAgNmx_N4bDiw==\" rel=\"nofollow\" target=\"_blank\">X<\/a>.<\/p>\n<p>\n        <strong>About Sanofi<\/strong><br \/>\n        <br \/>Sanofi is an R&amp;D driven, AI-powered biopharma company committed to improving people\u2019s lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more.\u202fOur team is guided by one purpose: we chase the miracles of science to improve people\u2019s lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time.<\/p>\n<p>Sanofi is listed on EURONEXT: SAN and NASDAQ: SNY.<\/p>\n<p>\n        <strong>Regeneron Media Relations<\/strong><br \/>\n        <br \/>Christina Chan\u00a0|\u00a0+1 914-383-6374 | <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=VZyqZrpZmuh_O-FuwDzowPC2CzJxE196PzUxcm6C71IF348Mil8EYljRCgv1brWvEts-6Y9_lwvzm2BTMFxC-Abx-1_le6j6o7NDQ9dDER0ETWi1fbg2jhHfO8lBVMIc\" rel=\"nofollow\" target=\"_blank\">christina.chan@regeneron.com<\/a><u>\u00a0<\/u><br \/>Alexandra Bowie\u00a0|\u00a0+1 914-346-0588 |\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=x_gM3sQZEHGu-xvfmkfrvFxXnn_N-I-XxXsWP-7SIgQRCx-sVNOdW-2hTnsfpFAV23x9RW6xe6d_U6--f4qjW5w8LZ2rVsW523VBI9Ur2sFDyQjUeqBZ9ZYKgkZ9s9Vn\" rel=\"nofollow\" target=\"_blank\">alexandra.bowie@regeneron.com<\/a><u>\u00a0<\/u><\/p>\n<p>\n        <strong>Regeneron Investor Relations<\/strong><br \/>\n        <br \/>Ryan Crowe\u00a0|\u00a0+1 914-847-8790 |\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=7Z9ZfnZpjzivO9f8I27_Jgtjnv4sbTKKGzHJiWAegA19jSvT7PLObXkdI3DHAT-x0bTOXHMEsWrYrXucZ7pMa5RyTKndHkhtRupzC6HSIW86GmUmJSi-Ji0moadJZX0m\" rel=\"nofollow\" target=\"_blank\">ryan.crowe@regeneron.com<\/a><br \/>Mark Hudson\u00a0|\u00a0+1 914-847-3482\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=H45NpwqUJbzEBM9cEJb5PwX57r-YmoSgvPP9Ae2_GHSz20fS2JTvK3FJ_Jzlnb948-7vPcKoSxFeifUdGefHuwkPHEz5HQ4pcmeCWTqPntinho9Evk8aJJEC90wJqCP6\" rel=\"nofollow\" target=\"_blank\">mark.hudson@regeneron.com<\/a><\/p>\n<p>\n        <strong>Sanofi Media Relations<\/strong><br \/>\n        <br \/>Sandrine Guendoul\u00a0|\u00a0+33 6 25 09 14 25\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=__7mre0OltkdXCCXsXKbT7rk4f8gqI0D83r8Lecb1Sguj88gczHVIkQErvdXM1MOxrONaJN6rWz2UybpQ_mzOq2EL2plsH3YaeXUKZIDigstdjvS1jrbLr51ezRI1ZdO\" rel=\"nofollow\" target=\"_blank\">sandrine.guendoul@sanofi.com<\/a><br \/>Evan Berland\u00a0|\u00a0+1 215 432 0234\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=SjdUGG3w6N31SVF0obsZaULfTx7kfNwJTK2jgCRmADqms9ViiAqv0_1rYZCzO_RHhSWgm2Wf4AKD_WtAUd9E6DpegTVWQ3zIdaCfQ_hogyhMC7BE_RU78hFqnciktioJ\" rel=\"nofollow\" target=\"_blank\">evan.berland@sanofi.com<\/a><br \/>L\u00e9o Le Bourhis\u00a0|\u00a0+33 6 75 06 43 81\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=crhC2DW0km-R_ii1rj1yGnT_Vcxvqq0GG-X_FTFcBYDCkIMegSvyBln17_rFvTu3sPHydhFtBUPn8_LTGUBUoGXbjp6H8ALRjuSnwoEdZlMgN2XI5tG6tnsG7EfuqL4j\" rel=\"nofollow\" target=\"_blank\">leo.lebourhis@sanofi.com<\/a><br \/>Victor Rouault\u00a0|\u00a0+1 617 356 4751\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=G1hmEqGGJxyASk96fz-PloWSlgWcdtNnodJplgy1ICRbN_WMlVRWUgIGFqXAM1SoPwI9Rh7Dl509P4Bvu8PRFNgdWhaen2Wq1Z33zN8UzbMo8hZsExYM7rcqh_DaeiZG\" rel=\"nofollow\" target=\"_blank\">victor.rouault@sanofi.com<\/a><br \/>Timothy Gilbert\u00a0|\u00a0+1 516 521 2929\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=NCEE7k5NklmpkI0einBM023nB_0_Q2SILITXDER98EXZdpzwjTy7GukN6VoPXikYE2wsD778hUnQdYZUzIUhPXP3fsntj3sSwNmEJDe4Z7PgfQId_caPIQxnytkT3zh_\" rel=\"nofollow\" target=\"_blank\">timothy.gilbert@sanofi.com<\/a><br \/>L\u00e9a Ubaldi\u202f|\u00a0+33 6 30 19 66 46\u00a0|\u202f<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=3cyjkXll0AOGdWiBFG-zZVeVEDmTkA_KX5Dz7DOxrwEFGmlrEyw7x148K-EWcOj_EoGVYFsvdes-jVg_psXhMlLMWwDwWIiGGC00i6-5SZ4=\" rel=\"nofollow\" target=\"_blank\">lea.ubaldi@sanofi.com<\/a><br \/>Ekaterina Pesheva\u00a0|\u00a0+1 410 926 6780\u00a0|\u202f<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UfvtvJrUQQBW5t8eUCEJhaJCxm2byxA6QRSn6V7FADgKSupUGvCdnk6NDMuZRPhcybTE_WoQ9YGGZl5XXbs9fQQdY-eiluAoAaXxHx98QWDMjTBSFOf1ytuUxRBIn_I2\" rel=\"nofollow\" target=\"_blank\">ekaterina.pesheva@sanofi.com<\/a><\/p>\n<p>\n        <strong>Sanofi Investor Relations<\/strong><br \/>\n        <br \/>Thomas Kudsk Larsen\u00a0|\u00a0+44 7545 513 693\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=KzLG5ppE0xE-pERrMpKWvMJkkqNG-9p7CUu7fy8jr0Q6LMQKjLJaasZ_LWbaFj-W77mR8dDzJ9H8cQoz8kxVNOBYG4u8UceGSkeLRPLaEhB1TiLJtMnAb3Z2wKhuyWhz\" rel=\"nofollow\" target=\"_blank\">thomas.larsen@sanofi.com<\/a><br \/>Aliz\u00e9 Kaisserian\u00a0|\u00a0+33 6 47 04 12 11\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=H-RPme10vFIxr9RCFhCq04ZofJuyWfJ8vBTpGNIi0qNnoziV9DCf_A2QfzviHZvgE5YGOhUARsKS0VEXZfGdjm_Go3aVu2FpjpF0FdXdnodGysOrvPXGxXO2epEAs-nW\" rel=\"nofollow\" target=\"_blank\">alize.kaisserian@sanofi.com<\/a><br \/>Keita Browne\u00a0|\u00a0+1 781 249 1766\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=UMD74UFJshO6m0es3dbTurXQTUrjxjN5KuKOCcyBmZ6wqnkvHreBv45N3A9Z7T-NPOCRmLarVnZsVb9ljupqhlgtQwEj_cYnZke0SSJe-AhNDZg0PkBWQARkXhRN3Hk6\" rel=\"nofollow\" target=\"_blank\">keita.browne@sanofi.com<\/a><br \/>Nathalie Pham\u00a0|\u00a0+33 7 85 93 30 17\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=8styRd6u5N0fPCWFPdDi2_Iw50E-tjxZjnQYuBMb6ZPIIYbbOf31T8LeJIRNUFLg3IiHYGcFzvE72nBCJHO8ufknnp-FyUQtzVn1aNzPZFRMcy29Iybm89TPHIGLK4B1\" rel=\"nofollow\" target=\"_blank\">nathalie.pham@sanofi.com<\/a><br \/>Nina Goworek\u00a0|\u00a0+1 908 569 7086\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fUOkUJJGA3l8mUtkv_U4qfsBk1mWU5xIqiK3Hs2-8UMlgd6lJCkLouz-hEwN2idNdbVSOx8Kum5LkgGRy1rBmlnMElC760Tl_tZHBBkdz4__6VGPdkfq8DArgbw8q1GK\" rel=\"nofollow\" target=\"_blank\">nina.goworek@sanofi.com<\/a><br \/>Thibaud Ch\u00e2telet\u00a0|\u00a0+33 6 80 80 89 90\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=OsDlXEFLCU_nOO_1dJPAaC7s-ECVtByySZZc5BRLCuVr6LhiLZWOhdyw2Tdh5OvkECfJAVahAICNg4q47ViDRluCXGso2PviaP4QzTJKANVvss9CzxTPAy4BOJB3V8fD\" rel=\"nofollow\" target=\"_blank\">thibaud.chatelet@sanofi.com<\/a><br \/>Yun Li\u00a0|\u00a0+33 6 84 00 90 72\u00a0|\u00a0<a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fAKcZrTxzajleKdnWVVJP9x2PwzPtW3W94FoT5-KBIWzsV69X0pikyFOl-1OLMrzth32cLWaYuP1ug5fC0WxN6R5NNBcVkz3g9qBamQ0js0=\" rel=\"nofollow\" target=\"_blank\">yun.li3@sanofi.com<\/a><\/p>\n<p>\n        <strong>Regeneron Forward-Looking Statements and Use of Digital Media<\/strong><br \/>\n        <br \/>\n        <em>This press release includes forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals, Inc. (\u201cRegeneron\u201d or the \u201cCompany\u201d), and actual events or results may differ materially from these forward-looking statements. Words such as \u201canticipate,\u201d \u201cexpect,\u201d \u201cintend,\u201d \u201cplan,\u201d \u201cbelieve,\u201d \u201cseek,\u201d \u201cestimate,\u201d variations of such words, and similar expressions are intended to identify such forward-looking statements, although not all forward-looking statements contain these identifying words. These statements concern, and these risks and uncertainties include, among others, the nature, timing, and possible success and therapeutic applications of products marketed or otherwise commercialized by Regeneron and\/or its collaborators or licensees (collectively, \u201cRegeneron\u2019s Products\u201d) and product candidates being developed by Regeneron and\/or its collaborators or licensees (collectively, \u201cRegeneron\u2019s Product Candidates\u201d) and research and clinical programs now underway or planned, including without limitation<\/em><br \/>\n        <em>the research and clinical programs discussed or referenced in this press release such as those evaluating Regeneron-discovered antibodies targeting interleukin-13 (IL-13), interleukin-4 (IL-4), and interleukin-4 receptor alpha (IL-4R\u03b1) as well as a bispecific antibody targeting IL-4xIL-13; the potential for any license, collaboration, or supply agreement, including Regeneron\u2019s amended license and collaboration agreement with Sanofi discussed in this press release, to be cancelled or terminated without realizing the expected benefits of such agreement; uncertainty of the utilization, market acceptance, and\/or commercial success of Regeneron\u2019s Products and Regeneron\u2019s Product Candidates and the impact of studies (whether conducted by Regeneron or others and whether mandated or voluntary), including the studies discussed or referenced in this press release, on any of the foregoing or any potential regulatory approval of Regeneron\u2019s Products and Regeneron\u2019s Product Candidates (such as those referenced above); the extent to which the results from the research and development programs conducted by Regeneron and\/or its collaborators or licensees (including based on the amended license and collaboration agreement discussed in this press release) may be replicated in other studies and\/or lead to advancement of product candidates to clinical trials, therapeutic applications, or regulatory approval; the likelihood, timing, and scope of possible regulatory approval and commercial launch of Regeneron\u2019s Product Candidates and new indications for Regeneron\u2019s Products, such as those referenced above; the ability of Regeneron\u2019s collaborators, licensees, suppliers, or other third parties (as applicable) to perform manufacturing, filling, finishing, packaging, labeling, distribution, and other steps related to Regeneron\u2019s Products and Regeneron\u2019s Product Candidates; the ability of Regeneron to manage supply chains for multiple products and product candidates and risks associated with tariffs and other trade restrictions; safety issues resulting from the administration of Regeneron\u2019s Products and Regeneron\u2019s Product Candidates (such as those referenced above) in patients, including serious complications or side effects in connection with the use of Regeneron\u2019s Products and Regeneron\u2019s Product Candidates in clinical trials; determinations by regulatory and administrative governmental authorities which may delay or restrict Regeneron\u2019s ability to continue to develop or commercialize Regeneron\u2019s Products and Regeneron\u2019s Product Candidates; ongoing regulatory obligations and oversight impacting Regeneron\u2019s Products, research and clinical programs, and business, including those relating to patient privacy; the availability and extent of reimbursement or copay assistance for Regeneron\u2019s Products from third-party payors and other third parties, including private payor healthcare and insurance programs, health maintenance organizations, pharmacy benefit management companies, and government programs such as Medicare and Medicaid; coverage and reimbursement determinations by such payors and other third parties and new policies and procedures adopted by such payors and other third parties; changes to drug pricing regulations and requirements and Regeneron\u2019s pricing strategy, including in connection with Regeneron\u2019s April 2026 agreements with the U.S. government; other changes in laws, regulations, and policies affecting the healthcare industry; competing products and product candidates (including biosimilar products) that may be superior to, or more cost effective than, Regeneron\u2019s Products and Regeneron\u2019s Product Candidates; unanticipated expenses; the costs of developing, producing, and selling products; the ability of Regeneron to meet any of its financial projections or guidance and changes to the assumptions underlying those projections or guidance; the impact of public health outbreaks, epidemics, or pandemics on Regeneron&#8217;s business; and risks associated with litigation and other proceedings and government investigations relating to the Company and\/or its operations (including the pending civil proceedings initiated or joined by the U.S. Department of Justice and the U.S. Attorney&#8217;s Office for the District of Massachusetts), risks associated with intellectual property of other parties and pending or future litigation relating thereto (including without limitation the patent litigation and other related proceedings relating to EYLEA<sup>\u00ae<\/sup> (aflibercept) Injection), the ultimate outcome of any such proceedings and investigations, and the impact any of the foregoing may have on Regeneron\u2019s business, prospects, operating results, and financial condition. A more complete description of these and other material risks can be found in Regeneron\u2019s filings with the U.S. Securities and Exchange Commission, including its Form 10-K for the year ended December 31, 2025 and its Form 10-Q for the quarterly period ended June 30, 2026. Any forward-looking statements are made based on management\u2019s current beliefs and judgment, and the reader is cautioned not to rely on any forward-looking statements made by Regeneron. Regeneron does not undertake any obligation to update (publicly or otherwise) any forward-looking statement, including without limitation any financial projection or guidance, whether as a result of new information, future events, or otherwise.<\/em>\n      <\/p>\n<p>\n        <em>Regeneron uses its media and investor relations website and social media outlets to publish important information about the Company, including information that may be deemed material to investors. Financial and other information about Regeneron is routinely posted and is accessible on Regeneron&#8217;s media and investor relations website (<\/em><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B-jOTYJYAlGZjH2hYywIHS-Rri4wdpCLGUR-dgU9ICHsmJIzU8Y5jwM49zCPr0UWS5WNYSsF9XsVkfSLitwr27LjPb--NIqI_9HmSSD1po3FAGCWcELWIyF5Ich4EeNS\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <em>https:\/\/investor.regeneron.com<\/em><br \/>\n        <\/a><br \/>\n        <em>) and its LinkedIn page (<\/em><br \/>\n        <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=B-jOTYJYAlGZjH2hYywIHfqMTnnGWr_Ie9nGav_njNgogyIpcsRHglxhvGptqJinT3_m33e_XWYW0kLES02jbE7vJE7K-Nhln4ljpL_gmhzlsEOwUsADe8kISnvfre-PzgojYScVrZtA5Pf7ypLsz4GZbTiaSjhTiblBQtI8SyniGaxdZ8BQmt8FWcM19OMqvnx69lbBxVprmK2cDv2ScA==\" rel=\"nofollow\" target=\"_blank\"><br \/>\n          <em>https:\/\/www.linkedin.com\/company\/regeneron-pharmaceuticals<\/em><br \/>\n        <\/a><br \/>\n        <em>).<\/em>\n      <\/p>\n<p>\n        <strong><br \/>\n          <em>Sanofi forward-looking statements<\/em><br \/>\n        <\/strong>\n      <\/p>\n<p align=\"justify\">\n        <em>This press release contains forward-looking statements within the meaning of applicable securities laws, including the Private Securities Litigation Reform Act of 1995, as amended. <\/em><br \/>\n        <br \/>\n        <em>Forward-looking statements are statements that are not historical facts. These statements include projections and estimates and their underlying assumptions, statements regarding plans, objectives, intentions, and expectations with respect to future financial results, events, operations, services, product development and potential, and statements regarding future events and economic performance. Words such as \u201cexpect,\u201d \u201canticipate,\u201d \u201cbelieve,\u201d \u201cintend,\u201d \u201cestimate,\u201d \u201cplan,\u201d \u201ccan,\u201d \u201ccontemplate,\u201d \u201ccould,\u201d \u201cis designed to,\u201d \u201cmay,\u201d \u201cmight,\u201d \u201cpotential,\u201d \u201cobjective,\u201d &#8220;attempt,&#8221; \u201ctarget,\u201d \u201cproject,\u201d &#8220;strategy,&#8221; &#8220;strive,&#8221; &#8220;desire,&#8221; \u201cpredict,\u201d \u201cforecast,\u201d \u201cambition,\u201d \u201cguideline,\u201d &#8220;seek,&#8221; \u201cshould,\u201d \u201cwill,\u201d &#8220;goal,&#8221; or the negative of these, and similar expressions are intended to identify forward-looking statements. <\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>Although Sanofi\u2019s management believes that the expectations reflected in such forward-looking statements are reasonable, investors are cautioned that forward-looking information and statements are subject to various risks and uncertainties, many of which are difficult to predict and generally beyond the control of Sanofi, that could cause actual results and developments to differ materially from those expressed in, or implied or projected by, the forward-looking information and statements. These risks and uncertainties include among other things, the uncertainties inherent in research and development, future clinical data and analysis, including post marketing, decisions by regulatory authorities, such as the U.S Food and Drug Administration or the European Medicines Agency, regarding whether and when to approve any drug, device or biological application that may be filed for any such product candidates as well as their decisions regarding labelling and other matters that could affect the availability or commercial potential of such product candidates; the fact that product candidates if approved may not be commercially successful; unexpected regulatory actions or delays, or government regulation generally; authorities\u2019 decisions regarding whether and when to approve a product candidate; political pressure in the United States to mandate lower drug prices including \u201cmost favored nation\u201d pricing for State Medicaid programs; the future approval and commercial success of therapeutic alternatives; Sanofi\u2019s ability to benefit from external growth opportunities, to complete related transactions and\/or obtain regulatory clearances, including future clinical data and analysis of existing clinical data relating to the product, including post marketing, unexpected safety, quality or manufacturing issues, competition in general; risks associated with intellectual property and any related pending or future litigation and the ultimate outcome of such litigation;\u00a0 trends in exchange rates and prevailing interest rates, volatile economic and market conditions, cost containment initiatives and subsequent changes thereto, and the impact that global crises may have on us, our customers, suppliers, vendors, and other business partners, and the financial condition of any one of them, as well as on our employees and on the global economy as a whole.\u00a0 The risks and uncertainties also include the uncertainties discussed or identified in the public filings with the SEC and the French Markest Authority (AMF) made by Sanofi, including those listed under \u201cRisk Factors\u201d and \u201cCautionary Statement Regarding Forward-Looking Statements\u201d in Sanofi\u2019s annual report on Form 20-F for the year ended December 31, 2025 or contained in our periodic reports on Form 6-K. Other than as required by applicable law, Sanofi does not undertake any obligation to update or revise any forward-looking information or statements. In light of these risks, uncertainties and assumptions, you should not place undue reliance on any forward-looking statements contained herein.<\/em>\n      <\/p>\n<p align=\"justify\">\n        <em>All trademarks mentioned in this press release are the property of the Sanofi group except for VelociSuite and Regeneron Genetics Center.<\/em>\n      <\/p>\n<p>      <img decoding=\"async\" alt=\"\" class=\"__GNW8366DE3E__IMG\" src=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgzNzU5OSM3ODczMzYyIzIwMDYyNTA=\" \/><br \/>\n      <br \/>\n      <img decoding=\"async\" alt=\"\" src=\"https:\/\/ml.globenewswire.com\/media\/MWQ2NGNmNjctMzA1Yi00MzNjLWE4ZTktNWRhMTU5MDlmMjJkLTEwMTc4MjMtMjAyNi0xMC0wMS1lbg==\/tiny\/Regeneron-Pharmaceuticals-Inc-.png\" \/>\n    <\/div>\n<div class=\"mw_contactinfo\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>REGN20423, a clinical-stage long-acting IL-13 monoclonal antibody invented and developed by Regeneron, is added to the alliance, along with a long-acting IL-4xIL-13 bispecific and two other long-acting preclinical antibodies from Regeneron Regeneron to receive $1 billion upfront with potential for up to an additional $7 billion in future milestone payments; companies to equally share development and commercialization costs, as well as any future profits Regeneron and Sanofi to host a conference call for investors and analysts today at 8:00 am ET\/2:00 pm CET TARRYTOWN, N.Y. and PARIS, Oct. 01, 2026 (GLOBE NEWSWIRE) &#8212; Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced an expansion of their long-standing antibody collaboration, adding multiple next-generation, long-acting antibodies to the alliance that has jointly &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-1007303","post","type-post","status-publish","format-standard","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies - Market Newsdesk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies - Market Newsdesk\" \/>\n<meta property=\"og:description\" content=\"REGN20423, a clinical-stage long-acting IL-13 monoclonal antibody invented and developed by Regeneron, is added to the alliance, along with a long-acting IL-4xIL-13 bispecific and two other long-acting preclinical antibodies from Regeneron Regeneron to receive $1 billion upfront with potential for up to an additional $7 billion in future milestone payments; companies to equally share development and commercialization costs, as well as any future profits Regeneron and Sanofi to host a conference call for investors and analysts today at 8:00 am ET\/2:00 pm CET TARRYTOWN, N.Y. and PARIS, Oct. 01, 2026 (GLOBE NEWSWIRE) &#8212; Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced an expansion of their long-standing antibody collaboration, adding multiple next-generation, long-acting antibodies to the alliance that has jointly &hellip; Continue reading &quot;Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies&quot;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/\" \/>\n<meta property=\"og:site_name\" content=\"Market Newsdesk\" \/>\n<meta property=\"article:published_time\" content=\"2026-10-01T05:06:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgzNzU5OSM3ODczMzYyIzIwMDYyNTA=\" \/>\n<meta name=\"author\" content=\"Newsdesk\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Newsdesk\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"15 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/\"},\"author\":{\"name\":\"Newsdesk\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/#\\\/schema\\\/person\\\/482f27a394d4fda80ecb5499e519d979\"},\"headline\":\"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies\",\"datePublished\":\"2026-10-01T05:06:07+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/\"},\"wordCount\":3066,\"image\":{\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.globenewswire.com\\\/newsroom\\\/ti?nf=OTgzNzU5OSM3ODczMzYyIzIwMDYyNTA=\",\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/\",\"url\":\"https:\\\/\\\/www.marketnewsdesk.com\\\/index.php\\\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\\\/\",\"name\":\"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies - 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Market Newsdesk","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/","og_locale":"en_US","og_type":"article","og_title":"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies - Market Newsdesk","og_description":"REGN20423, a clinical-stage long-acting IL-13 monoclonal antibody invented and developed by Regeneron, is added to the alliance, along with a long-acting IL-4xIL-13 bispecific and two other long-acting preclinical antibodies from Regeneron Regeneron to receive $1 billion upfront with potential for up to an additional $7 billion in future milestone payments; companies to equally share development and commercialization costs, as well as any future profits Regeneron and Sanofi to host a conference call for investors and analysts today at 8:00 am ET\/2:00 pm CET TARRYTOWN, N.Y. and PARIS, Oct. 01, 2026 (GLOBE NEWSWIRE) &#8212; Regeneron Pharmaceuticals, Inc. (NASDAQ: REGN) and Sanofi today announced an expansion of their long-standing antibody collaboration, adding multiple next-generation, long-acting antibodies to the alliance that has jointly &hellip; Continue reading \"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies\"","og_url":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/","og_site_name":"Market Newsdesk","article_published_time":"2026-10-01T05:06:07+00:00","og_image":[{"url":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgzNzU5OSM3ODczMzYyIzIwMDYyNTA=","type":"","width":"","height":""}],"author":"Newsdesk","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Newsdesk","Est. reading time":"15 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/#article","isPartOf":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/"},"author":{"name":"Newsdesk","@id":"https:\/\/www.marketnewsdesk.com\/#\/schema\/person\/482f27a394d4fda80ecb5499e519d979"},"headline":"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies","datePublished":"2026-10-01T05:06:07+00:00","mainEntityOfPage":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/"},"wordCount":3066,"image":{"@id":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/#primaryimage"},"thumbnailUrl":"https:\/\/www.globenewswire.com\/newsroom\/ti?nf=OTgzNzU5OSM3ODczMzYyIzIwMDYyNTA=","inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/","url":"https:\/\/www.marketnewsdesk.com\/index.php\/regeneron-and-sanofi-expand-global-alliance-with-multiple-next-generation-long-acting-immunology-antibodies\/","name":"Regeneron and Sanofi Expand Global Alliance with Multiple Next-Generation, Long-Acting Immunology Antibodies - 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